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Norepinephrine Bitartrate is an adrenergic receptor agonist, small molecule drug candidate. Along with Dextrose it is indicated for the treatment of severe, acute hypotension.
Lead Product(s): Norepinephrine Bitartrate,Dextrose
Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 11, 2024
Details:
Through agreement, Baxter’s exclusive rights to commercialize Toraymyxin (polymyxin B), a therapeutic hemoperfusion device that removes endotoxin, which can cause sepsis, from the bloodstream and is guided by Spectral’s Endotoxin Activity Assay.
Lead Product(s): Polymyxin B Sulfate
Therapeutic Area: Infections and Infectious Diseases Product Name: Toraymyxin
Highest Development Status: ApprovedProduct Type: Small molecule
Recipient: Spectral Medical
Deal Size: Undisclosed Upfront Cash: $5.0 million
Deal Type: Agreement February 21, 2024
Details:
Zosyn is a combination of piperacillin sodium, which exerts bactericidal activity by inhibiting septum formation and cell wall synthesis of susceptible bacteria and tazobactam sodium having activity against bacteria due to its reduced affinity to penicillin-binding proteins.
Lead Product(s): Piperacillin Sodium,Tazobactam Sodium
Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Zosyn
Highest Development Status: ApprovedProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 04, 2023
Details:
As part of the collaboration, Miromatrix has created a new liver therapy called miroliverELAP that combines a Miromatrix single-use bioengineered liver with Baxter’s PrisMax system for patients with acute liver failure (ALF) in need of organ support therapies.
Lead Product(s): MiroliverELAP
Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: MiroliverELAP
Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy
Recipient: United Therapeutics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration February 01, 2023
Details:
Inpremzia is an approved medicine used to treat people with diabetes who need insulin to keep their blood glucose (sugar) level controlled. It contains the active substance insulin human.
Lead Product(s): Insulin Lispro
Therapeutic Area: Endocrinology Product Name: Inpremzia
Highest Development Status: ApprovedProduct Type: Peptide
Partner/Sponsor/Collaborator: Biocon
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 25, 2022
Details:
Proceeds will be used for the development of companies lead drug AVT02. As part of the first round Shinhan from Korea, Baxter Healthcare SA from the US and ATHOS (Strüngmann Family Office) from Germany invested in Alvotech.
Lead Product(s): Adalimumab
Therapeutic Area: Dermatology Product Name: AVT02
Highest Development Status: Phase IIIProduct Type: Large molecule
Recipient: Alvotech
Deal Size: $100.0 million Upfront Cash: Undisclosed
Deal Type: Private Placement March 17, 2021
Details:
Baxter BioPharma Solutions will provide fill/finish sterile manufacturing services and supply packaging for approximately 60-90 million doses of the Moderna COVID-19 Vaccine in 2021.
Lead Product(s): mRNA-1273
Therapeutic Area: Infections and Infectious Diseases Product Name: mRNA-1273
Highest Development Status: ApprovedProduct Type: Vaccine
Partner/Sponsor/Collaborator: Moderna Therapeutics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Agreement March 08, 2021
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