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Details:
The net proceeds from the financing will be used to support the advancement of Accent's first-in-class DHX9 inhibitor for the treatment of triple-negative breast cancer, and ovarian cancer and a potentially best-in-class KIF18A inhibitor.
Lead Product(s): ATX968
Therapeutic Area: Oncology Product Name: ATX968
Highest Development Status: IND EnablingProduct Type: Small molecule
Partner/Sponsor/Collaborator: Bristol Myers Squibb
Deal Size: $75.0 million Upfront Cash: Undisclosed
Deal Type: Series C Financing January 23, 2024
Details:
The presentation will describe the first identification of potent and selective small molecule inhibitors of DHX9 that demonstrate tumor cell killing in both in vitro and in vivo preclinical cancer models.
Lead Product(s): Undisclosed
Therapeutic Area: Oncology Product Name: Undisclosed
Highest Development Status: PreclinicalProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 06, 2023
Details:
This collaboration combines Accent’s expertise in RMP-targeting therapeutics with Ipsen’s capabilities and proven track record in Oncology medicine development and commercialization.
Lead Product(s): Undisclosed
Therapeutic Area: Oncology Product Name: Undisclosed
Highest Development Status: PreclinicalProduct Type: Small molecule
Partner/Sponsor/Collaborator: Ipsen
Deal Size: $446.0 million Upfront Cash: Undisclosed
Deal Type: Collaboration October 18, 2021
Details:
Proceeds from the financing will be used to advance the development of Accent’s novel therapies targeting RNA-modifying proteins (RMPs), including its lead programs METTL3 and ADAR1.
Lead Product(s): METTL3
Therapeutic Area: Oncology Product Name: Undisclosed
Highest Development Status: UndisclosedProduct Type: Large molecule
Partner/Sponsor/Collaborator: EcoR1 Capital
Deal Size: $63.0 million Upfront Cash: Undisclosed
Deal Type: Series B Financing April 23, 2020