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    Chemistry

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    Also known as:
    Molecular Formula
    C8H11N5O3
    Molecular Weight
    225.20  g/mol
    InChI Key
    MKUXAQIIEYXACX-UHFFFAOYSA-N
    Aciclovir
    1 2D Structure

    Aciclovir

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
    2.1.2 InChI
    InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
    2.1.3 InChI Key
    MKUXAQIIEYXACX-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=NC2=C(N1COCCO)NC(=NC2=O)N
    2.1.5 Isomeric SMILES
    C1=NC2=C(N1COCCO)NC(=NC2=O)N
    2.2 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 225.20 g/mol
    Molecular Formula C8H11N5O3
    XLogP3-1.6
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count4
    Exact Mass225.08618923 g/mol
    Monoisotopic Mass225.08618923 g/mol
    Topological Polar Surface Area115 A^2
    Heavy Atom Count16
    Formal Charge0
    Complexity308
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 8  
    Drug NameAcyclovir
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Capsule; Suspension
    RouteTopical; Oral
    Strength5%; 200mg/5ml; 200mg; 800mg; 400mg
    Market StatusPrescription
    CompanyAmneal Pharms; Mylan Pharms; Ranbaxy; Hetero Labs Ltd V; Hi Tech Pharma; Actavis Mid Atlantic; Teva; Cadila Pharms; Apotex; Zydus Pharms Usa; Carlsbad; Mylan; Stason; Dava Pharms

    2 of 8  
    Drug NameAcyclovir sodium
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelAcyclovir is a synthetic nucleoside analog active against herpes viruses. Acyclovir for Injection USP is a sterile lyophilized powder for intravenous administration only. Each 500 mg vial contains 500 mg of acyclovir and 49 mg of sodium, and each 100...
    Active IngredientAcyclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 50mg base/ml; eq 500mg base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyBedford; Fresenius Kabi Usa; Aurobindo Pharma

    3 of 8  
    Drug NameSitavig
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelSITAVIG (acyclovir) buccal tablet is applied topically to the gum and releases acyclovir as the buccal tablet gradually dissolves [see ClinicalPharmacology (12.3)]. Acyclovir is a synthetic purine nucleoside analogue active against herpes viruses. Th...
    Active IngredientAcyclovir
    Dosage FormTablet
    RouteBuccal
    Strength50mg
    Market StatusPrescription
    CompanyInnocutis Holdings

    4 of 8  
    Drug NameZovirax
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Cream; Capsule; Suspension
    RouteOral; Topical
    Strength200mg/5ml; 200mg; 800mg; 400mg; 5%
    Market StatusPrescription
    CompanyDelcor Asset; Valeant Bermuda

    5 of 8  
    Drug NameAcyclovir
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Capsule; Suspension
    RouteTopical; Oral
    Strength5%; 200mg/5ml; 200mg; 800mg; 400mg
    Market StatusPrescription
    CompanyAmneal Pharms; Mylan Pharms; Ranbaxy; Hetero Labs Ltd V; Hi Tech Pharma; Actavis Mid Atlantic; Teva; Cadila Pharms; Apotex; Zydus Pharms Usa; Carlsbad; Mylan; Stason; Dava Pharms

    6 of 8  
    Drug NameAcyclovir sodium
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelAcyclovir is a synthetic nucleoside analog active against herpes viruses. Acyclovir for Injection USP is a sterile lyophilized powder for intravenous administration only. Each 500 mg vial contains 500 mg of acyclovir and 49 mg of sodium, and each 100...
    Active IngredientAcyclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 50mg base/ml; eq 500mg base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyBedford; Fresenius Kabi Usa; Aurobindo Pharma

    7 of 8  
    Drug NameSitavig
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelSITAVIG (acyclovir) buccal tablet is applied topically to the gum and releases acyclovir as the buccal tablet gradually dissolves [see ClinicalPharmacology (12.3)]. Acyclovir is a synthetic purine nucleoside analogue active against herpes viruses. Th...
    Active IngredientAcyclovir
    Dosage FormTablet
    RouteBuccal
    Strength50mg
    Market StatusPrescription
    CompanyInnocutis Holdings

    8 of 8  
    Drug NameZovirax
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Cream; Capsule; Suspension
    RouteOral; Topical
    Strength200mg/5ml; 200mg; 800mg; 400mg; 5%
    Market StatusPrescription
    CompanyDelcor Asset; Valeant Bermuda

    API Reference Price

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CHINA 317321 SDNF China","customerAddress":"ACME PLAZA, ANDHERI KURLA ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1743100200,"product":"ACYCLOVIR ACYCLOVIR","address":"Floor No.22, Plot No.1, Survey No.83\/1, Galaxy Tower","city":"Hyderabad","supplier":"CHARIOTEER","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"APITORIA PHARMA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"9900.00","actualQuantity":"9900","unit":"KGS","unitRateFc":"36","totalValueFC":"359207.9","currency":"N\/A","unitRateINR":"3142.8","date":"28-Mar-2025","totalValueINR":"31113720","totalValueInUsd":"359207.9","indian_port":"Vizag Sea","hs_no":"29335990","bill_no":"9165544","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"CO LTD TONGYUANXI DAZHAN XIANJU ZHEJIANG PROVINCE PR CHINA","customerAddress":"Floor No.22, Plot No.1, Survey No.83\/1, Galaxy Tower"}]
    05-Jan-2021
    31-Mar-2025
    KGS
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    DOSAGE - CAPSULE;ORAL - 200MG **Federal Regis...DOSAGE - CAPSULE;ORAL - 200MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 18828

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    DOSAGE - SUSPENSION;ORAL - 200MG/5ML

    USFDA APPLICATION NUMBER - 19909

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    DOSAGE - TABLET;ORAL - 400MG **Federal Regist...DOSAGE - TABLET;ORAL - 400MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20089

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    DOSAGE - TABLET;ORAL - 800MG **Federal Regist...DOSAGE - TABLET;ORAL - 800MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20089

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    DOSAGE - CREAM;TOPICAL - 5%;1%

    USFDA APPLICATION NUMBER - 22436

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    01

    Brand Name : Sitavig

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    Acyclovir

    Drug Cost (USD) : 29,067

    Year : 2022

    Prescribers : 22

    Prescriptions : 26

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    Brand Name : Xerese

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    Acyclovir/Hydrocortisone

    Drug Cost (USD) : 452,625

    Year : 2022

    Prescribers : 203

    Prescriptions : 311

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    Acyclovir

    Drug Cost (USD) : 61,319

    Year : 2021

    Prescribers : 16

    Prescriptions : 32

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    04

    Brand Name : Xerese

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    Acyclovir/Hydrocortisone

    Drug Cost (USD) : 488,534

    Year : 2021

    Prescribers : 226

    Prescriptions : 322

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    Acyclovir

    Drug Cost (USD) : 58,465,531

    Year : 2020

    Prescribers : 669360

    Prescriptions : 1874611

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    Brand Name : Sitavig

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    Acyclovir

    Drug Cost (USD) : 54,435

    Year : 2020

    Prescribers : 24

    Prescriptions : 26

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    Brand Name : Xerese

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    Acyclovir/Hydrocortisone

    Drug Cost (USD) : 513,363

    Year : 2020

    Prescribers : 247

    Prescriptions : 348

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    Acyclovir

    Drug Cost (USD) : 57,743,896

    Year : 2019

    Prescribers : 688687

    Prescriptions : 1852608

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    Acyclovir/Hydrocortisone

    Drug Cost (USD) : 1,919,014

    Year : 2019

    Prescribers : 255

    Prescriptions : 364

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    Acyclovir

    Drug Cost (USD) : 4,974,615

    Year : 2019

    Prescribers : 2976

    Prescriptions : 4449

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    ABOUT THIS PAGE

    Looking for / Aciclovir API manufacturers, exporters & distributors?

    Aciclovir manufacturers, exporters & distributors 1

    59

    PharmaCompass offers a list of Aciclovir API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Aciclovir manufacturer or Aciclovir supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Aciclovir manufacturer or Aciclovir supplier.

    PharmaCompass also assists you with knowing the Aciclovir API Price utilized in the formulation of products. Aciclovir API Price is not always fixed or binding as the Aciclovir Price is obtained through a variety of data sources. The Aciclovir Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Aciclovir

    Zovirax Oral Acyclovir (ACV) Suspension Manufacturers

    A Zovirax Oral Acyclovir (ACV) Suspension manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Zovirax Oral Acyclovir (ACV) Suspension, including repackagers and relabelers. The FDA regulates Zovirax Oral Acyclovir (ACV) Suspension manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Zovirax Oral Acyclovir (ACV) Suspension API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension Suppliers

    A Zovirax Oral Acyclovir (ACV) Suspension supplier is an individual or a company that provides Zovirax Oral Acyclovir (ACV) Suspension active pharmaceutical ingredient (API) or Zovirax Oral Acyclovir (ACV) Suspension finished formulations upon request. The Zovirax Oral Acyclovir (ACV) Suspension suppliers may include Zovirax Oral Acyclovir (ACV) Suspension API manufacturers, exporters, distributors and traders.

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension USDMF

    A Zovirax Oral Acyclovir (ACV) Suspension DMF (Drug Master File) is a document detailing the whole manufacturing process of Zovirax Oral Acyclovir (ACV) Suspension active pharmaceutical ingredient (API) in detail. Different forms of Zovirax Oral Acyclovir (ACV) Suspension DMFs exist exist since differing nations have different regulations, such as Zovirax Oral Acyclovir (ACV) Suspension USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Zovirax Oral Acyclovir (ACV) Suspension DMF submitted to regulatory agencies in the US is known as a USDMF. Zovirax Oral Acyclovir (ACV) Suspension USDMF includes data on Zovirax Oral Acyclovir (ACV) Suspension's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Zovirax Oral Acyclovir (ACV) Suspension USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension suppliers with USDMF on PharmaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Zovirax Oral Acyclovir (ACV) Suspension Drug Master File in Japan (Zovirax Oral Acyclovir (ACV) Suspension JDMF) empowers Zovirax Oral Acyclovir (ACV) Suspension API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Zovirax Oral Acyclovir (ACV) Suspension JDMF during the approval evaluation for pharmaceutical products. At the time of Zovirax Oral Acyclovir (ACV) Suspension JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension suppliers with JDMF on PharmaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Zovirax Oral Acyclovir (ACV) Suspension Drug Master File in Korea (Zovirax Oral Acyclovir (ACV) Suspension KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Zovirax Oral Acyclovir (ACV) Suspension. The MFDS reviews the Zovirax Oral Acyclovir (ACV) Suspension KDMF as part of the drug registration process and uses the information provided in the Zovirax Oral Acyclovir (ACV) Suspension KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Zovirax Oral Acyclovir (ACV) Suspension KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Zovirax Oral Acyclovir (ACV) Suspension API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension suppliers with KDMF on PharmaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension CEP

    A Zovirax Oral Acyclovir (ACV) Suspension CEP of the European Pharmacopoeia monograph is often referred to as a Zovirax Oral Acyclovir (ACV) Suspension Certificate of Suitability (COS). The purpose of a Zovirax Oral Acyclovir (ACV) Suspension CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Zovirax Oral Acyclovir (ACV) Suspension EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Zovirax Oral Acyclovir (ACV) Suspension to their clients by showing that a Zovirax Oral Acyclovir (ACV) Suspension CEP has been issued for it. The manufacturer submits a Zovirax Oral Acyclovir (ACV) Suspension CEP (COS) as part of the market authorization procedure, and it takes on the role of a Zovirax Oral Acyclovir (ACV) Suspension CEP holder for the record. Additionally, the data presented in the Zovirax Oral Acyclovir (ACV) Suspension CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Zovirax Oral Acyclovir (ACV) Suspension DMF.

    A Zovirax Oral Acyclovir (ACV) Suspension CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Zovirax Oral Acyclovir (ACV) Suspension CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension suppliers with CEP (COS) on PharmaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension WC

    A Zovirax Oral Acyclovir (ACV) Suspension written confirmation (Zovirax Oral Acyclovir (ACV) Suspension WC) is an official document issued by a regulatory agency to a Zovirax Oral Acyclovir (ACV) Suspension manufacturer, verifying that the manufacturing facility of a Zovirax Oral Acyclovir (ACV) Suspension active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Zovirax Oral Acyclovir (ACV) Suspension APIs or Zovirax Oral Acyclovir (ACV) Suspension finished pharmaceutical products to another nation, regulatory agencies frequently require a Zovirax Oral Acyclovir (ACV) Suspension WC (written confirmation) as part of the regulatory process.

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension suppliers with Written Confirmation (WC) on PharmaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Zovirax Oral Acyclovir (ACV) Suspension as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Zovirax Oral Acyclovir (ACV) Suspension API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Zovirax Oral Acyclovir (ACV) Suspension as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Zovirax Oral Acyclovir (ACV) Suspension and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Zovirax Oral Acyclovir (ACV) Suspension NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Zovirax Oral Acyclovir (ACV) Suspension suppliers with NDC on PharmaCompass.

    Zovirax Oral Acyclovir (ACV) Suspension GMP

    Zovirax Oral Acyclovir (ACV) Suspension Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Zovirax Oral Acyclovir (ACV) Suspension GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Zovirax Oral Acyclovir (ACV) Suspension GMP manufacturer or Zovirax Oral Acyclovir (ACV) Suspension GMP API supplier for your needs.

    Zovirax Oral Acyclovir (ACV) Suspension CoA

    A Zovirax Oral Acyclovir (ACV) Suspension CoA (Certificate of Analysis) is a formal document that attests to Zovirax Oral Acyclovir (ACV) Suspension's compliance with Zovirax Oral Acyclovir (ACV) Suspension specifications and serves as a tool for batch-level quality control.

    Zovirax Oral Acyclovir (ACV) Suspension CoA mostly includes findings from lab analyses of a specific batch. For each Zovirax Oral Acyclovir (ACV) Suspension CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Zovirax Oral Acyclovir (ACV) Suspension may be tested according to a variety of international standards, such as European Pharmacopoeia (Zovirax Oral Acyclovir (ACV) Suspension EP), Zovirax Oral Acyclovir (ACV) Suspension JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Zovirax Oral Acyclovir (ACV) Suspension USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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