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Chemistry

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Also known as: Zed-1227, 1542132-88-6, T4sr539ykf, Zed1227, Tak-227, Methyl (e,6s)-7-[[1-[2-(2-ethylbutylamino)-2-oxoethyl]-2-oxopyridin-3-yl]amino]-6-[(3-methylimidazole-4-carbonyl)amino]-7-oxohept-2-enoate
Molecular Formula
C26H36N6O6
Molecular Weight
528.6  g/mol
InChI Key
VHGWUSABWIEXKQ-BEBFYNPSSA-N
FDA UNII
T4SR539YKF

Vilagletistat
ZED-1227 is under investigation in clinical trial NCT05305599 (Different Doses of ZED1227 vs. Placebo in NAFLD).
1 2D Structure

Vilagletistat

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl (E,6S)-7-[[1-[2-(2-ethylbutylamino)-2-oxoethyl]-2-oxo-3-pyridinyl]amino]-6-[(3-methylimidazole-4-carbonyl)amino]-7-oxohept-2-enoate
2.1.2 InChI
InChI=1S/C26H36N6O6/c1-5-18(6-2)14-28-22(33)16-32-13-9-11-20(26(32)37)30-24(35)19(10-7-8-12-23(34)38-4)29-25(36)21-15-27-17-31(21)3/h8-9,11-13,15,17-19H,5-7,10,14,16H2,1-4H3,(H,28,33)(H,29,36)(H,30,35)/b12-8+/t19-/m0/s1
2.1.3 InChI Key
VHGWUSABWIEXKQ-BEBFYNPSSA-N
2.2 Other Identifiers
2.2.1 UNII
T4SR539YKF
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Zed1227

2.3.2 Depositor-Supplied Synonyms

1. Zed-1227

2. 1542132-88-6

3. T4sr539ykf

4. Zed1227

5. Tak-227

6. Methyl (e,6s)-7-[[1-[2-(2-ethylbutylamino)-2-oxoethyl]-2-oxopyridin-3-yl]amino]-6-[(3-methylimidazole-4-carbonyl)amino]-7-oxohept-2-enoate

7. Methyl (e,6s)-7-((1-(2-(2-ethylbutylamino)-2-oxoethyl)-2-oxopyridin-3-yl)amino)-6-((3-methylimidazole-4-carbonyl)amino)-7-oxohept-2-enoate

8. Refchem:195896

9. Unii-t4sr539ykf

10. Chembl4081588

11. Methyl (s,e)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-6-(1-methyl-1h-imidazole-5-carboxamido)-7-oxohept-2-enoate

12. (2e,6s)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-1,2-dihydro-2-oxo-3-pyridinyl)amino)-6-(((1-methyl-1h-imidazol-5-yl)carbonyl)amino)-7-oxo-2-heptenoic Acid Methyl Ester

13. Methyl (e,6s)-7-((1-(2-(2-ethylbutylamino)-2-oxo-ethyl)-2-oxo-3-pyridyl)amino)-6-((3-methylimidazole-4-carbonyl)amino)-7-oxo-hept-2-enoate

14. (2e,6s)-7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1h-imidazol-5-yl)carbonyl]amino]-7-oxo-2-heptenoic Acid Methyl Ester

15. 2-heptenoic Acid, 7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-1,2-dihydro-2-oxo-3-pyridinyl)amino)-6-(((1-methyl-1h-imidazol-5-yl)carbonyl)amino)-7-oxo-, Methyl Ester, (2e,6s)-

16. 2-heptenoic Acid, 7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1h-imidazol-5-yl)carbonyl]amino]-7-oxo-, Methyl Ester, (2e,6s)-

17. Methyl (2e,6s)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-1,2-dihydro-2-oxo-3-pyridinyl)amino)-6-(((1-methyl-1h-imidazol-5-yl)carbonyl)amino)-7-oxo-2-heptenoate

18. Methyl (2e,6s)-7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1h-imidazol-5-yl)carbonyl]amino]-7-oxo-2-heptenoate

19. Glutaminase

20. Vilagletistat [inn]

21. Orb1706443

22. Schembl16751074

23. Ex-a7845r

24. Gtpl12802

25. (2e,6s)-7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1h-imidazol-5-yl)carbonyl]amino]-7-oxo-2-heptenoicacidmethylester

26. Bdbm50245478

27. Akos040742843

28. Hy-19359

29. Ms-29784

30. Cs-0015432

31. G15912

32. (2e,6s)-7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1h-imidazol-5-yl)carbonyl]amino]-7-oxo-2-heptenoic Acid Methyl Ester; (2e,6s)-7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1h-imidazol-5-yl)carbonyl]amino]-7-oxo-2-heptenoic Acid Methyl Ester

2.4 Create Date
2014-03-03
3 Chemical and Physical Properties
Molecular Weight 528.6 g/mol
Molecular Formula C26H36N6O6
XLogP31.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count15
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area152
Heavy Atom Count38
Formal Charge0
Complexity958
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1542132-88-6 / Vilagletistat API manufacturers, exporters & distributors?

Vilagletistat manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Vilagletistat API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Vilagletistat manufacturer or Vilagletistat supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Vilagletistat manufacturer or Vilagletistat supplier.

API | Excipient name

Vilagletistat

Synonyms

Zed-1227, 1542132-88-6, T4sr539ykf, Zed1227, Tak-227, Methyl (e,6s)-7-[[1-[2-(2-ethylbutylamino)-2-oxoethyl]-2-oxopyridin-3-yl]amino]-6-[(3-methylimidazole-4-carbonyl)amino]-7-oxohept-2-enoate

Cas Number

1542132-88-6

Unique Ingredient Identifier (UNII)

T4SR539YKF

About Vilagletistat

ZED-1227 is under investigation in clinical trial NCT05305599 (Different Doses of ZED1227 vs. Placebo in NAFLD).

Vilagletistat Manufacturers

A Vilagletistat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Vilagletistat, including repackagers and relabelers. The FDA regulates Vilagletistat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Vilagletistat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Vilagletistat Suppliers

A Vilagletistat supplier is an individual or a company that provides Vilagletistat active pharmaceutical ingredient (API) or Vilagletistat finished formulations upon request. The Vilagletistat suppliers may include Vilagletistat API manufacturers, exporters, distributors and traders.

Vilagletistat GMP

Vilagletistat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Vilagletistat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Vilagletistat GMP manufacturer or Vilagletistat GMP API supplier for your needs.

Vilagletistat CoA

A Vilagletistat CoA (Certificate of Analysis) is a formal document that attests to Vilagletistat's compliance with Vilagletistat specifications and serves as a tool for batch-level quality control.

Vilagletistat CoA mostly includes findings from lab analyses of a specific batch. For each Vilagletistat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Vilagletistat may be tested according to a variety of international standards, such as European Pharmacopoeia (Vilagletistat EP), Vilagletistat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Vilagletistat USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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