Valacyclovir

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

14 API Suppliers, 1 EU WC, 13 Listed Suppliers

DEVELOPMENTS

17 Drug(s) in Development

17 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Exports, FDF Imports

INTERMEDIATES

6 Suppliers

6 Suppliers

DOSSIERs // Finished Dosage Formulations

189 Dossiers, 110 Europe, 47 Australia, 21 South Africa, 11 Listed Dossiers

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 89 Finished Drug Prices

MARKET PLACE

4 APIs, 3 DOSSIERS // FDF

ANALYTICAL SOLUTION(s)

11 Other Ref. Standards

11 Other Ref. Standards

DIGITAL CONTENT

6 News

6 News

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

209

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

110

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

219.00

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as:

Molecular Formula

C₁₃H₂₀N₆O₄

Molecular Weight

324.34 g/mol

InChI Key

HDOVUKNUBWVHOX-QMMMGPOBSA-N

1 2D Structure

Valacyclovir

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate

2.1.2 InChI

InChI=1S/C13H20N6O4/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20)/t8-/m0/s1

2.1.3 InChI Key

HDOVUKNUBWVHOX-QMMMGPOBSA-N

2.1.4 Canonical SMILES

CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N

2.1.5 Isomeric SMILES

CC(C)[C@@H](C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N

2.2 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₃H₂₀N₆O₄
Molecular Weight	324.34 g/mol
XLogP3	-0.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	8
Exact Mass	324.15460314 g/mol
Monoisotopic Mass	324.15460314 g/mol
Topological Polar Surface Area	147 A^2
Heavy Atom Count	23
Formal Charge	0
Complexity	483
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Valtrex
PubMed Health	Valacyclovir (By mouth)
Drug Classes	Antiviral
Drug Label	VALTREX (valacyclovir hydrochloride) is the hydrochloride salt of the L-valyl ester of the antiviral drug acyclovir.VALTREX Caplets are for oral administration. Each caplet contains valacyclovir hydrochloride equivalent to 500mg or 1gram valacycl...
Active Ingredient	Valacyclovir hydrochloride
Dosage Form	Tablet
Route	oral; Oral
Strength	eq 500mg base; eq 1gm base
Market Status	Prescription
Company	Glaxosmithkline

2 of 2
Drug Name	Valtrex
PubMed Health	Valacyclovir (By mouth)
Drug Classes	Antiviral
Drug Label	VALTREX (valacyclovir hydrochloride) is the hydrochloride salt of the L-valyl ester of the antiviral drug acyclovir.VALTREX Caplets are for oral administration. Each caplet contains valacyclovir hydrochloride equivalent to 500mg or 1gram valacycl...
Active Ingredient	Valacyclovir hydrochloride
Dosage Form	Tablet
Route	oral; Oral
Strength	eq 500mg base; eq 1gm base
Market Status	Prescription
Company	Glaxosmithkline