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1. Calcium Trimetaphosphate
2. Magnesium Trimetaphosphate
3. Trimetaphosphoric Acid
4. Trimetaphosphoric Acid, 99tc-labeled Cpd
5. Trimetaphosphoric Acid, Calcium (2:3) Salt, Hexahydrate
6. Trimetaphosphoric Acid, Magnesium (2:3) Salt
7. Trimetaphosphoric Acid, Magnesium (2:3) Salt, Dodecahydrate
8. Trimetaphosphoric Acid, Ruthenium (+3) Salt
9. Trimetaphosphoric Acid, Tripotassium Salt
10. Trimetaphosphoric Acid, Trisodium Salt
1. 7785-84-4
2. Trisodium Trimetaphosphate
3. Sodium Trimetaphosphate [usan]
4. 3ih6169rl0
5. Cyclicsodiumtrimetaphosphate
6. Trisodium;2,4,6-trioxido-1,3,5,2lambda5,4lambda5,6lambda5-trioxatriphosphinane 2,4,6-trioxide
7. Sodium Trimetaphosphate (usan)
8. Trisodium Metaphosphate
9. Polyrinsan 58
10. Cyclic Sodium Trimetaphosphate
11. Sodium Phosphate ((napo3)3)
12. Hsdb 5048
13. Metaphosphoric Acid, Trisodium Salt
14. Sodium Metaphosphate (na3(p3o9))
15. Einecs 232-088-3
16. Trisodium Trimetaphosphate (na3p3o9)
17. Cyclisches Trinatriummetaphosphat [german]
18. Unii-3ih6169rl0
19. Ccris 8524
20. Cyclisches Trinatriummetaphosphat
21. Metaphosphoric Acid (h3p3o9), Trisodium Salt
22. Trimetaphosphoric Acid (h3p3o9), Trisodium Salt
23. 1,3,5,2,4,6-trioxatriphosphorinane, 2,4,6-trihydroxy-, Trisodium Salt
24. Ec 232-088-3
25. Chembl2107557
26. Dtxsid7052789
27. Trimetaphosphate Grade Iii Trisodium
28. Sodium Trimetaphosphate [ii]
29. Sodium Trimetaphosphate [mi]
30. Mfcd00867826
31. Sodium Trimetaphosphate [fcc]
32. Sodium Trimetaphosphate [hsdb]
33. Sodium Trimetaphosphate [inci]
34. Sodium Trimetaphosphate [vandf]
35. D02423
36. E75943
37. Metaphosphoric Acid (h3p3o9), Sodium Salt (1:3)
38. Q7553388
39. (triphosphoric Acid Alpha,beta,gamma-trisodium)alpha,gamma-anhydride Salt
40. 2,4,6-tris(sodiooxy)-1,3,5,2,4,6-trioxatriphosphorinane 2,4,6-trioxide
| Molecular Weight | 305.89 g/mol |
|---|---|
| Molecular Formula | Na3O9P3 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 0 |
| Exact Mass | 305.84482541 g/mol |
| Monoisotopic Mass | 305.84482541 g/mol |
| Topological Polar Surface Area | 148 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 224 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 4 |
Cariostatic Agents
National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)
EXPTL USE: A 3-YR STUDY ON SCHOOL-AGE CHILDREN USING SODIUM TRIMETAPHOSPHATE AS A CHEWING GUM ADDITIVE PRODUCED REDUCTIONS IN PROXIMAL SURFACE DENTAL CARIES INCREMENTS AS COMPARED TO A NONCHEWING GUM GROUP. THE REDUCTIONS WERE 23.3% FOR THE SODIUM TRIMETAPHOSPHATE SUCROSE GUM GROUP & 47.6% FOR THE SODIUM TRIMETAPHOSPHATE NONSUGAR GROUP AS COMPARED TO THE NO-GUM GROUP. ... A MARGINAL EFFECT ON OVERALL CARIES INCREMENTS CAN BE ASCRIBED TO THE AGENT. THIS OVERALL EFFECT RESULTED FROM A SIGNIFICANT REDUCTION OF CARIES ON THE PROXIMAL SURFACES OF TEETH, ALTHOUGH OTHER SURFACES WERE NOT AS PROTECTED. ... THE LEVEL OF PROTECTION PROVIDED BY SODIUM TRIMETAPHOSPHATE IN THIS STUDY, OR BY DIETARY PHOSPHATES IN GENERAL, APPEARS SMALL RELATIVE TO OTHER CARIES-PREVENTING AGENTS, SUCH AS TOPICAL FLUORIDES.
PMID:273637 FINN SB ET AL; J AM DENT ASSOC 96 (4): 651-5 (1978)
SODIUM TRIMETAPHOSPHATE ADDED TO CHEWING GUM IS OF MARGINAL VALUE IN REDUCING DENTAL CARIES ON PROXIMAL SURFACES OF PERMANENT TEETH.
FINN SB ET AL; US NTIS PB REP ISS PB-273581 1-70 (1976)
Cariostatic Agents
Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed) (See all compounds classified as Cariostatic Agents.)
... LITTLE, IF ANY, CYCLIC METAPHOSPHATE IS ABSORBED THRU INTESTINAL WALL WHEN ADMIN ORALLY. THE METAPHOSPHATES MUST FIRST BE HYDROLYZED TO TRIPOLYPHOSPHATE & NEXT TO ORTHOPHOSPHATE, WHICH THEN CAN BE ABSORBED.
Furia, T.E. (ed.). CRC Handbook of Food Additives. 2nd ed. Cleveland: The Chemical Rubber Co., 1972., p. 642
Condensed phosphates (CP) used as food additives depressed the growth of 7 strains of Streptococcus mutans (serotype a-g) as assessed by disk diffusion methods. Minimal inhibitory concn (MIC) of condensed phosphates on Streptococcus mutans appeared to be related to their chelating capacity. The antibacterial action of condensed phosphates seemed largely bacteriostatic. Condensed phosphates depressed lactate production from glucose and sucrose by the cells of strain Kl-R. Condensed phosphates depressed insoluble glucan production from sucrose by the cells of Kl-R. The inhibition of sugar metabolism may be due to the interference of sugar transport into Streptococcus mutans induced by the chelation effects of condensed phosphates. Hamsters were inoculated orally with strain Kl-R and reared on the high-sucrose diet No 2000 supplemented with 2% (wt/wt) condensed phosphates for 60 days. Dietary supplements of condensed phosphates were associated with reduced caries activity and plaque formation.
PMID:6961893 Shibata H, Morioka T; Arch Oral Biol 27 (10): 809-16 (1982)
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