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1. Triethylamine Acetate
2. Triethylamine Dinitrate
3. Triethylamine Hydrobromide
4. Triethylamine Hydrochloride
5. Triethylamine Maleate (1:1)
6. Triethylamine Phosphate
7. Triethylamine Phosphate (1:1)
8. Triethylamine Phosphonate (1:1)
9. Triethylamine Sulfate
10. Triethylamine Sulfate (2:1)
11. Triethylamine Sulfite (1:1)
12. Triethylamine Sulfite (2:1)
13. Triethylammonium Formate
1. N,n-diethylethanamine
2. 121-44-8
3. (diethylamino)ethane
4. Ethanamine, N,n-diethyl-
5. Triethylamin
6. Triethyl Amine
7. Triaethylamin
8. Trietilamina
9. N,n,n-triethylamine
10. Net3
11. Trietylamine
12. Tri-ethyl Amine
13. (c2h5)3n
14. Mfcd00009051
15. N,n-diethyl-ethanamine
16. Vou728o6ay
17. Chebi:35026
18. Diethylaminoethane
19. Triethylamine, >=99.5%
20. Triaethylamin [german]
21. Trietilamina [italian]
22. Ccris 4881
23. Hsdb 896
24. Et3n
25. Ten [base]
26. Einecs 204-469-4
27. Un1296
28. Unii-vou728o6ay
29. Triehtylamine
30. Triehylamine
31. Trieihylamine
32. Triethlyamine
33. Triethyamine
34. Triethylamine 100ml
35. Triethylamme
36. Triethylarnine
37. Thethylamine
38. Triethlamine
39. Triethyiamine
40. Triethylannine
41. Tri-ethylamine
42. Triehyl Amine
43. Triethyl Amin
44. Triethylam Ine
45. Triethylami-ne
46. Triethylamine-
47. Trietyl Amine
48. Tri Ethyl Amine
49. Triethyl- Amine
50. Ai3-15425
51. Green Tea 95%
52. N, N-diethylethanamine
53. Green Tea Pe 50%
54. Green Tea Pe 90%
55. N,n,n-triethylamine #
56. Triethylamine, 99.5%
57. Triethylamine, >=99%
58. Triethylamine [un1296] [flammable Liquid]
59. Dsstox_cid_4366
60. Triethylamine [mi]
61. Ec 204-469-4
62. N(et)3
63. Dsstox_rid_77381
64. Nciopen2_006503
65. Triethylamine [fhfi]
66. Triethylamine [hsdb]
67. Triethylamine [inci]
68. Dsstox_gsid_24366
69. Bidd:er0331
70. Triethylamine (reagent Grade)
71. Triethylamine, Lr, >=99%
72. Triethylamine [usp-rs]
73. (ch3ch2)3n
74. Chembl284057
75. N(ch2ch3)3
76. Green Tea Extract (50/30)
77. Green Tea Extract (90/40)
78. Dtxsid3024366
79. Fema No. 4246
80. Triethylamine, Hplc, 99.6%
81. Triethylamine, P.a., 99.0%
82. Green Tea Extract 50% Material
83. Triethylamine, Analytical Standard
84. Adal1185352
85. Bcp07310
86. N(c2h5)3
87. Triethylamine, For Synthesis, 99%
88. Zinc1242720
89. Tox21_200873
90. Triethylamine, 99.7%, Extra Pure
91. Green Tea Powder & Powder Extract
92. Stl282722
93. Akos000119998
94. Triethylamine, Purum, >=99% (gc)
95. Triethylamine, Zero2(tm), >=99%
96. Zinc112977393
97. Un 1296
98. Ncgc00248857-01
99. Ncgc00258427-01
100. Triethylamine 100 Microg/ml In Methanol
101. Cas-121-44-8
102. Triethylamine, Bioultra, >=99.5% (gc)
103. Triethylamine, Saj First Grade, >=98.0%
104. Ft-0688146
105. T0424
106. Triethylamine 100 Microg/ml In Acetonitrile
107. Triethylamine [un1296] [flammable Liquid]
108. Triethylamine, Trace Metals Grade, 99.99%
109. Triethylamine, Saj Special Grade, >=98.0%
110. Triethylamine, Puriss. P.a., >=99.5% (gc)
111. Q139199
112. J-004499
113. J-525077
114. F0001-0344
115. Triethylamine, For Amino Acid Analysis, >=99.5% (gc)
116. Z137796018
117. Triethylamine, For Protein Sequence Analysis, Ampule, >=99.5% (gc)
118. Triethylamine, United States Pharmacopeia (usp) Reference Standard
| Molecular Weight | 101.19 g/mol |
|---|---|
| Molecular Formula | C6H15N |
| XLogP3 | 1.4 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 3 |
| Exact Mass | 101.120449483 g/mol |
| Monoisotopic Mass | 101.120449483 g/mol |
| Topological Polar Surface Area | 3.2 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 25.7 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
The pharmacokinetics of the industrially important compound triethylamine (TEA) and its metabolite triethylamine-N-oxide (TEAO) were studied in four volunteers after oral and intravenous administration. TEA was efficiently absorbed from the gastrointestinal (GI) tract, rapidly distributed, and in part metabolized into TEAO. There was no significant first pass metabolism. TEAO was also well absorbed from the GI tract. Within the GI tract, TEAO was reduced into TEA (19%) and dealkylated into diethylamine (DEA; 10%). The apparent volumes of distribution during the elimination phase were 192 liters for TEA and 103 liters for TEAO. Gastric intubation showed that there was a close association between levels of TEA in plasma and gastric juice, the latter levels being 30 times higher. The TEA and TEAO in plasma had half-lives of about 3 and 4 hr, respectively. Exhalation of TEA was minimal. More than 90% of the dose was recovered in the urine as TEA and TEAO. The urinary clearances of TEA and TEAO indicated that in addition to glomerular filtration, tubular secretion takes place. For TEAO at high levels, the secretion appears to be saturable. The present data, in combination with those of earlier studies, indicate that the sum of TEA and TEAO in urine may be used for biological monitoring of exposure to TEA.
PMID:2781570 Akesson B et al; Toxicol Appl Pharmacol 100 (3): 529-38 (1989)
The objectives of the study were to assess triethylamine (TEA) exposure in cold-box core making and to study the applicability of urinary TEA measurement in exposure evaluation. Air samples were collected by pumping of air through activated-charcoal-filled glass tubes, and pre- and postshift urine samples were collected. The TEA concentrations were determined by gas chromatography. TEA was measured in air and urine samples from the same shift. Breathing-zone measurements of 19 workers in 3 foundries were included in the study, and stationary and continuous air measurements were also made in the same foundries. Pre- and postshift urine samples were analyzed for their TEA and triethylamine-N-oxide (TEAO) concentrations. The TEA concentration range was 0.3-23 mg/cu m in the breathing zone of the core makers. The mean 8-hr time-weighted average exposure levels were 1.3, 4.0, and 13 mg/cu m for the three foundries. Most of the preshift urinary TEA concentrations were under the detection limit, whereas the postshift urinary TEA concentrations ranged between 5.6 and 171 mmol/mol creatinine. The TEAO concentrations were 4-34% (mean 19%) of the summed TEA + TEAO concentrations. The correlation between air and urine measurements was high (r=0.96, p<0.001). A TEA air concentration of 4.1 mg/cu m (the current ACGIH 8-hr time-weighted average threshold limit value) corresponded to a urinary concentration of 36 mmol/mol creatinine.
PMID:9439991 Jarvinen P, Engstrom K; Int Arch Occup Environ Health 70(6): 424-7 (1997)
In 20 workers studied before, during, and after exposure to triethylamine (TEA) in a polyurethane-foam producing plant the amount of TEA and its metabolite triethylamine-N-oxide (TEAO) excreted in urine corresponded to an average of 80% of the inhaled amount. An average of 27% was TEAO, but with a pronounced interindividual variation. Older subjects excreted more than younger ones; less than 0.3% was excreted as diethylamine.
PMID:2782314 Akesson B et al; Am J Ind Med; 16 (3): 255-65 (1989)
There have been few studies on the metabolism of industrially important aliphatic amines such as triethylamine. It is generally assumed that amines not normally present in the body are metabolized by monoamine oxidase and diamine oxidase (histaminase). Monoamine oxidase catalyzes the deamination of primary, secondary, and tertiary amines. ... Ultimately ammonia is formed and will be converted to urea. The hydrogen peroxide formed is acted upon by catalase and the aldehyde formed is thought to be converted to the corresponding carboxylic acid by the action of aldehyde oxidase.
Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 131
Five healthy volunteers were exposed by inhalation to triethylamine (TEA; four or eight hours at about 10, 20, 35, and 50 mg/cu m), a compound widely used as a curing agent in polyurethane systems. Analysis of plasma and urine showed that an average of 24% of the TEA was biotransformed into triethylamine-N-oxide (TEAO) but with a wide interindividual variation (15-36%). The TEA and TEAO were quantitatively eliminated in the urine. The plasma and urinary concentrations of TEA and TEAO decreased rapidly after the end of exposure (average half time of TEA was 3.2 hr).
PMID:3378003 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1007987 Akesson B et al; Br J Ind Med 45 (4): 262-8 (1988)
In 20 workers studied before, during, and after exposure to triethylamine (TEA) in a polyurethane-foam producing plant the amount of TEA and its metabolite triethylamine-N-oxide (TEAO) excreted in urine corresponded to an average of 80% of the inhaled amount. An average of 27% was TEAO, but with a pronounced interindividual variation. Older subjects excreted more than younger ones; less than 0.3% was excreted as diethylamine.
PMID:2782314 Akesson B et al; Am J Ind Med; 16 (3): 255-65 (1989)
After oral dose of triethylamine to four men, triethylamine in plasma had a half-life of about 3 hr (range, 2.4-3.5 hr).
PMID:2781570 Akesson B et al; Toxicol Appl Pharmacol 100 (3): 529-38 (1989)
Plasma half-life after inhalation exposure to five volunteers was 3.2 hr.
PMID:3378003 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1007987 Akesson B et al; Br J Ind Med 45 (4): 262-8 (1988)
In 20 workers studied before, during, and after exposure to triethylamine (TEA) in a polyurethane-foam producing plant the amount of TEA and its metabolite triethylamine-N-oxide (TEAO) excreted in urine corresponded to an average of 80% of the inhaled amount. ... The data indicate half-lives for TEA and TEAO excretion in urine of about 3 hr.
PMID:2782314 Akesson B et al; Am J Ind Med; 16 (3): 255-65 (1989)
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