menu
    • menu

    Find Topiramate manufacturers, exporters & distributors on PharmaCompass

    LGM Topiramate

    Virtual Booth

    Contact Supplier

    Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

    Virtual Booth

    Contact Supplier

    Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

    Virtual Booth

    Contact Supplier

    Balpharma Topiramate

    Virtual Booth

    Contact Supplier

    Transo-Pharm GmbH works globally to supply Active Pharmaceutical Ingredients adhering to the highest quality & GMP standards.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2025-01-20

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    DEVELOPMENTS

    INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    DRUG PRODUCT COMPOSITIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    MARKET PLACE

    PATENTS & EXCLUSIVITIES

    REF. STANDARDS & IMPURITIES

    PharmaCompass

    Synopsis

    Related ProductsRelated Products

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: 97240-79-4, Topamax, Epitomax, Topamax sprinkle, Topina, Mcn-4853
    Molecular Formula
    C12H21NO8S
    Molecular Weight
    339.36  g/mol
    InChI Key
    KJADKKWYZYXHBB-XBWDGYHZSA-N
    FDA UNII
    0H73WJJ391
    Topiramate
    A sulfamate-substituted fructose analog that was originally identified as a hypoglycemic agent. It is used for the treatment of EPILEPSY and MIGRAINE DISORDERS, and may also promote weight loss.
    The mechanism of action of topiramate is as a Cytochrome P450 3A4 Inducer, and Cytochrome P450 2C19 Inhibitor. The physiologic effect of topiramate is by means of Decreased Central Nervous System Disorganized Electrical Activity.
    1 2D Structure

    Topiramate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl sulfamate
    2.1.2 InChI
    InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1
    2.1.3 InChI Key
    KJADKKWYZYXHBB-XBWDGYHZSA-N
    2.1.4 Canonical SMILES
    CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C
    2.1.5 Isomeric SMILES
    CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C
    2.2 Other Identifiers
    2.2.1 UNII
    0H73WJJ391
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2,3-4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose Sulfamate

    2. Epitomax

    3. Mcn 4853

    4. Mcn-4853

    5. Mcn4853

    6. Topamax

    7. Usl255

    2.3.2 Depositor-Supplied Synonyms

    1. 97240-79-4

    2. Topamax

    3. Epitomax

    4. Topamax Sprinkle

    5. Topina

    6. Mcn-4853

    7. Tipiramate

    8. Topiramatum

    9. Topimax

    10. Topomax

    11. Tipiramato

    12. Topiramato

    13. Epitoma

    14. Topamac

    15. Mcn 4853

    16. Rwj-17021

    17. Rwj-17021-000

    18. C12h21no8s

    19. 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose Sulfamate

    20. Sincronil

    21. Usl255

    22. Qudexy

    23. Usl-255

    24. 2,3:4,5-di-o-isopropylidene-beta-d-fructopyranose Sulfamate

    25. (-)-topiramate

    26. [(3as,5ar,8ar,8bs)-2,2,7,7-tetramethyltetrahydro-3ah-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl Sulfamate

    27. Chebi:63631

    28. Tipiramate [french]

    29. Tipiramato [spanish]

    30. 0h73wjj391

    31. ((3as,5ar,8ar,8bs)-2,2,7,7-tetramethyltetrahydro-3ah-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl Sulfamate

    32. Topiramatum [inn-latin]

    33. Topiramatum [latin]

    34. Topiramato [inn-spanish]

    35. Mfcd00865320

    36. Dsstox_cid_3688

    37. Dsstox_rid_77148

    38. Dsstox_gsid_23688

    39. ((3as,5ar,8ar,8bs)-2,2,7,7-tetramethyltetrahydro-3ah-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl)methyl Sulfamate

    40. [(1r,2s,6s,9r)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl Sulfamate

    41. Tpm

    42. Topiragen

    43. Topax

    44. Trokendi Xr

    45. Qudexy Xr

    46. Smr000466325

    47. Topiramate (tpm)

    48. Tor

    49. Topamax (tn)

    50. Cas-97240-79-4

    51. Rwj 17021

    52. Brn 5988957

    53. Unii-0h73wjj391

    54. Hsdb 7531

    55. Sulfamate 7

    56. 3hku

    57. 3lxe

    58. Usl 255

    59. Topiramate [usan:usp:inn:ban]

    60. Topiramate Solution

    61. Ncgc00095181-01

    62. [(3as,5ar,8ar,8bs)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[5,4-b:5',3'-d]pyran-3a-yl]methyl Sulfamate

    63. Topiramate- Bio-x

    64. Trokendi Xr (tn)

    65. Eprontia

    66. Ks-1122

    67. Topiramate [mi]

    68. Topiramate [inn]

    69. Topiramate [jan]

    70. Spectrum2_001128

    71. Topiramate [hsdb]

    72. Topiramate [inci]

    73. Topiramate [usan]

    74. Beta-d-fructopyranose, 2,3:4,5-bis-o-(1-methylethylidene)-, Sulfamate

    75. Topiramate [vandf]

    76. Cbchromo1_000352

    77. Topiramate [mart.]

    78. Topiramate [usp-rs]

    79. Topiramate [who-dd]

    80. Bidd:pxr0127

    81. Schembl34631

    82. Bspbio_002306

    83. Topiramate (jan/usp/inn)

    84. Eprontia (liquid Formulation)

    85. Mls000759431

    86. Mls001424070

    87. Bidd:gt0854

    88. Spectrum1505801

    89. Spbio_000995

    90. Chembl220492

    91. Gtpl6849

    92. Dtxsid8023688

    93. Topiramate [orange Book]

    94. Bdbm10887

    95. 2,3:4,5-di-o-isopropylidene-b-d-fructopyranose Sulfamate

    96. Topiramate [ep Monograph]

    97. Topiramate [usp Impurity]

    98. Qsymia Component Topiramate

    99. Hms1922h06

    100. Hms2051l09

    101. Hms2093d20

    102. Hms2232h21

    103. Hms3414c15

    104. Hms3678c15

    105. Hms3715i12

    106. Hms3884c17

    107. Pharmakon1600-01505801

    108. Topiramate [usp Monograph]

    109. [(3as,5ar,8ar,8bs)-2,2,7,7-tetramethyltetrahydro-3ah-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl Sulfamate (non-preferred Name)

    110. Act09031

    111. Albb-022457

    112. Hy-b0122

    113. Tox21_111472

    114. Tox21_302401

    115. Nsc759251

    116. S1438

    117. Zinc95616603

    118. Topiramate Component Of Qsymia

    119. .beta.-d-fructopyranose, 2,3:4,5-bis-o-(1-methylethylidene)-, Sulfamate

    120. Akos000424547

    121. Topiramate 1.0 Mg/ml In Acetonitrile

    122. Topiramate, >=98% (hplc), Solid

    123. Tox21_111472_1

    124. Ccg-100940

    125. Cs-1885

    126. Db00273

    127. Nc00190

    128. Nsc 759251

    129. Nsc-759251

    130. Ncgc00178714-01

    131. Ncgc00178714-04

    132. Ncgc00178714-18

    133. Ncgc00255221-01

    134. Bt167048

    135. Sbi-0206907.p001

    136. Sw197570-3

    137. C07502

    138. D00537

    139. F20536

    140. Ab00639961-06

    141. Ab00639961-08

    142. Ab00639961_09

    143. Ab00639961_10

    144. 240t794

    145. A900173

    146. Q221174

    147. Sr-01000759409

    148. W-60376

    149. Q-201845

    150. Sr-01000759409-4

    151. Z1522553470

    152. Topiramate, United States Pharmacopeia (usp) Reference Standard

    153. 2,3:4,5-bis-o-(1-methylethylidene)-?-d-fructopyranose Sulfamate

    154. 2,3:4,5-di-o-isopropylidene-.beta.-d-fructopyranose Sulfamate

    155. Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material

    156. .beta.-d-fructopyranose, 2,3:4,5-bis-o-(1-methylethylidene)-, 1-sulfamate

    157. Topiramate Solution, 1.0 Mg/ml In Methanol, Ampule Of 1 Ml, Certified Reference Material

    158. [(1r,2s,6s,9r)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl Sulfamate

    159. [(3as,5ar,8ar,8bs)-2,2,7,7-tetramethyl-5,5a,8a,8b-tetrahydrodi[1,3]dioxolo[4,5-a:5',3'-d]pyran-3a-yl]methyl Sulfamate

    160. 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose 1-sulfamate;2,3:4,5-di-o-isopropylidene-beta-d-fructopyranose Sulfamate; Topamax; Tracrium; Toiramate:

    2.4 Create Date
    2005-11-20
    3 Chemical and Physical Properties
    Molecular Weight 339.36 g/mol
    Molecular Formula C12H21NO8S
    XLogP3-0.8
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count3
    Exact Mass339.09878780 g/mol
    Monoisotopic Mass339.09878780 g/mol
    Topological Polar Surface Area124 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity556
    Isotope Atom Count0
    Defined Atom Stereocenter Count4
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 6  
    Drug NameTopamax
    PubMed HealthTopiramate (By mouth)
    Drug ClassesAnticonvulsant, Central Nervous System Agent
    Drug LabelTopiramate is a sulfamate-substituted monosaccharide. TOPAMAX (topiramate) Tablets are available as 25 mg, 50 mg, 100 mg, and 200 mg round tablets for oral administration. TOPAMAX (topiramate capsules) Sprinkle Capsules are available as 15 mg and...
    Active IngredientTopiramate
    Dosage FormTablet; Capsule
    RouteOral
    Strength200mg; 25mg; 15mg; 100mg; 50mg
    Market StatusPrescription
    CompanyJanssen Pharms