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Synopsis

Synopsis

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Chemistry

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Also known as: 24237-54-5, Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate, Nonflamin (free base), Tinoridine [inn], Y 3642, Y-3642
Molecular Formula
C17H20N2O2S
Molecular Weight
316.4  g/mol
InChI Key
PFENFDGYVLAFBR-UHFFFAOYSA-N
FDA UNII
C9Z9ICZ7YR

Tinoridine
Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
1 2D Structure

Tinoridine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
ethyl 2-amino-6-benzyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
2.1.2 InChI
InChI=1S/C17H20N2O2S/c1-2-21-17(20)15-13-8-9-19(11-14(13)22-16(15)18)10-12-6-4-3-5-7-12/h3-7H,2,8-11,18H2,1H3
2.1.3 InChI Key
PFENFDGYVLAFBR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC(=O)C1=C(SC2=C1CCN(C2)CC3=CC=CC=C3)N
2.2 Other Identifiers
2.2.1 UNII
C9Z9ICZ7YR
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)-pyridine-3-carboxylic Acid Ethyl Ester

2. Nonflamin

3. Nonflamine

4. Tinoridin

5. Tinoridine Hydrochloride

6. Tinoridine Monohydrochloride

7. Y 3642

8. Y-3642

2.3.2 Depositor-Supplied Synonyms

1. 24237-54-5

2. Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate

3. Nonflamin (free Base)

4. Tinoridine [inn]

5. Y 3642

6. Y-3642

7. Nsc 158555

8. C9z9icz7yr

9. Nsc-158555

10. Ethyl 2-amino-6-benzyl-5,7-dihydro-4h-thieno[2,3-c]pyridine-3-carboxylate

11. Chembl592943

12. Dtxsid9023677

13. Tinoridine (inn)

14. 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine

15. Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine-3-carboxylate

16. Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno-[2,3-c]pyridine-3-carboxylate

17. 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine-3-carboxylic Acid Ethyl Ester

18. Ncgc00159451-02

19. Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c]pyridine-3-carboxylate

20. Thieno(2,3-c)pyridine-3-carboxylic Acid, 2-amino-6-benzyl-4,5,6,7-tetrahydro-, Ethyl Ester

21. Thieno[2,3-c]pyridine-3-carboxylic Acid, 2-amino-4,5,6,7-tetrahydro-6-(phenylmethyl)-, Ethyl Ester

22. Dtxcid403677

23. Tinoridino

24. Tinoridinum

25. Tinoridinum [inn-latin]

26. Tinoridino [inn-spanish]

27. 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic Acid Ethyl Ester

28. Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (tinoridine)

29. Thieno(2,3-c)pyridine-3-carboxylic Acid, 2-amino-4,5,6,7-tetrahydro-6-(phenylmethyl)-, Ethyl Ester

30. Cas-24237-54-5

31. Einecs 246-102-0

32. Unii-c9z9icz7yr

33. Brn 1082341

34. Tinoridine [mi]

35. Maybridge2_000001

36. Cbmicro_018439

37. 2-amino-3-aethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridin

38. 2-amino-3-aethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridin [german]

39. Tinoridine [who-dd]

40. Oprea1_041651

41. Oprea1_798781

42. Schembl24761

43. Mls004774001

44. Chebi:135353

45. Pfenfdgyvlafbr-uhfffaoysa-n

46. Hms1303a01

47. Bcp12825

48. Ccg-6706

49. Tox21_111678

50. Bdbm50304470

51. Mfcd00401417

52. Nsc158555

53. Akos000267028

54. Tox21_111678_1

55. Db13001

56. Hy-w032848

57. 2-amino-6-benzyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic Acid Ethyl Ester

58. Idi1_001041

59. Thieno(2,3-c)pyridine-3-carboxylic Acid, 4,5,6,7-tetrahydro-2-amino-6-benzyl-, Ethyl Ester

60. Ncgc00159451-03

61. Ncgc00159451-04

62. Ncgc00159451-05

63. Ncgc00159451-06

64. Ac-27457

65. As-35595

66. Smr000103196

67. Bim-0018431.p001

68. Cs-0076872

69. Ft-0645518

70. Ns00027593

71. En300-03920

72. D08602

73. J-015409

74. J-524972

75. Sr-01000644920-1

76. Q27275368

77. Z56176137

78. F1673-2635

79. Thieno[2, 2-amino-6-benzyl-4,5,6,7-tetrahydro-, Ethyl Ester

80. Ethyl 2-amino-6-benzyl-4h,5h,6h,7h-thieno[2,3-c]pyridine-3-carboxylate

81. Thieno[2, 2-amino-4,5,6,7-tetrahydro-6-(phenylmethyl)-, Ethyl Ester

82. Ethyl 2-amino-6-(phenylmethyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate

83. Ethyl 2-amino-6-benzyl-5, 7-dihydro-4h-thieno[2, 3-c]pyridine-3-carboxylate

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 316.4 g/mol
Molecular Formula C17H20N2O2S
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area83.8
Heavy Atom Count22
Formal Charge0
Complexity387
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


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Looking for 24237-54-5 / Tinoridine API manufacturers, exporters & distributors?

Tinoridine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Tinoridine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Tinoridine manufacturer or Tinoridine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tinoridine manufacturer or Tinoridine supplier.

PharmaCompass also assists you with knowing the Tinoridine API Price utilized in the formulation of products. Tinoridine API Price is not always fixed or binding as the Tinoridine Price is obtained through a variety of data sources. The Tinoridine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Tinoridine

Synonyms

24237-54-5, Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate, Nonflamin (free base), Tinoridine [inn], Y 3642, Y-3642

Cas Number

24237-54-5

Unique Ingredient Identifier (UNII)

C9Z9ICZ7YR

About Tinoridine

Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).

Tinoridine Manufacturers

A Tinoridine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tinoridine, including repackagers and relabelers. The FDA regulates Tinoridine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tinoridine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Tinoridine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Tinoridine Suppliers

A Tinoridine supplier is an individual or a company that provides Tinoridine active pharmaceutical ingredient (API) or Tinoridine finished formulations upon request. The Tinoridine suppliers may include Tinoridine API manufacturers, exporters, distributors and traders.

click here to find a list of Tinoridine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Tinoridine GMP

Tinoridine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tinoridine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tinoridine GMP manufacturer or Tinoridine GMP API supplier for your needs.

Tinoridine CoA

A Tinoridine CoA (Certificate of Analysis) is a formal document that attests to Tinoridine's compliance with Tinoridine specifications and serves as a tool for batch-level quality control.

Tinoridine CoA mostly includes findings from lab analyses of a specific batch. For each Tinoridine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tinoridine may be tested according to a variety of international standards, such as European Pharmacopoeia (Tinoridine EP), Tinoridine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tinoridine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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