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Chemistry

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Also known as: 137330-13-3, Tilmicosin (phosphate), Tilmicosin phosphate [usan], Ly177370 phosphate, Micotil 300, Smh7u1s683
Molecular Formula
C46H83N2O17P
Molecular Weight
967.1  g/mol
InChI Key
NESIVXZOSKKUDP-ARVJLQODSA-N
FDA UNII
SMH7U1S683

Tilmicosin Phosphate
1 2D Structure

Tilmicosin Phosphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-7-[2-[(3S,5R)-3,5-dimethylpiperidin-1-yl]ethyl]-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione;phosphoric acid
2.1.2 InChI
InChI=1S/C46H80N2O13.H3O4P/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45;1-5(2,3)4/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3;(H3,1,2,3,4)/b15-14+,25-19+;/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-;/m1./s1
2.1.3 InChI Key
NESIVXZOSKKUDP-ARVJLQODSA-N
2.1.4 Canonical SMILES
CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)O)N(C)C)O)CCN3CC(CC(C3)C)C)C)C)COC4C(C(C(C(O4)C)O)OC)OC.OP(=O)(O)O
2.1.5 Isomeric SMILES
CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O)N(C)C)O)CCN3C[C@@H](C[C@@H](C3)C)C)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC.OP(=O)(O)O
2.2 Other Identifiers
2.2.1 UNII
SMH7U1S683
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin

2. El 870

3. El-870

4. Micotil 300

5. Tilmicosin

2.3.2 Depositor-Supplied Synonyms

1. 137330-13-3

2. Tilmicosin (phosphate)

3. Tilmicosin Phosphate [usan]

4. Ly177370 Phosphate

5. Micotil 300

6. Smh7u1s683

7. Tilmicosin Phosphate (usan)

8. (4r,5s,6s,7r,9r,11e,13e,15r,16r)-6-[(2r,3r,4s,5s,6r)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-7-[2-[(3s,5r)-3,5-dimethylpiperidin-1-yl]ethyl]-16-ethyl-4-hydroxy-15-[[(2r,3r,4r,5r,6r)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione;phosphoric Acid

9. Tilmicosinphosphate

10. Pulmotil 90

11. Unii-smh7u1s683

12. Tilmicosin Phosphate, Usp

13. Schembl1184136

14. Chembl2105782

15. Hy-b0905a

16. Ly-177370 Phosphate

17. Dtxsid201019820

18. 20-deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin Phosphate

19. Mfcd06797805

20. S5573

21. Tilmicosin Phosphate [mart.]

22. Ccg-270598

23. Cs-4729

24. Tilmicosin Phosphate [green Book]

25. 4a-o-de(2,6-dideoxy-3-c-methyl-alpha-l-ribo-hexopyranosyl)-20-deoxo-20-(cis-3,5-dimethylpiperidino)tylosin Phosphate (1:1) (salt)

26. Tylosin, 4a-o-de(2,6-dideoxy-3-c-methyl-alpha-l-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)-, (20(cis))-, Phosphate (1:1) (salt)

27. D02493

28. 330t133

29. Q-201834

30. Q27289281

31. Tilmicosin Phosphate, Antibiotic For Culture Media Use Only

32. (4r,5s,6s,7r,9r,11e,13e,15r,16r)-6-{[(2r,3r,4s,5s,6r)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-7-{2-[(3r,5s)-3,5-dimethylpiperidin-1-yl]ethyl}-16-ethyl-4-hydroxy-15-({[(2r,3r,4r,5r,6r)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione; Phosphoric Acid

33. 4 Sup(a)-o-de(2,6-dideoxy-3-c-methyl-.alpha.-l-ribo-hexopyranosyl)-20-deoxo-20-(cis-3,5-dimethylpiperidino)tylosin Phosphate (1:1) (salt)

34. 4(sup A)-o-de(2,6-dideoxy-3-c-methyl-alpha-l-ribo-hexopyranosyl)-20-deoxo-20-(cis-3,5-dimethylpiperidino)tylosin Phosphate (1:1) (salt)

35. Tylosin, 4 Sup(a)-o-de(2,6-dideoxy-3-c-methyl-.alpha.-l-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)-, (20(cis))-, Phosphate (1:1) (salt)

36. Tylosin, 4(sup A)-o-de(2,6-dideoxy-3-c-methyl-alpha-l-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)-, (20(cis))-, Phosphate (1:1) (salt)

2.4 Create Date
2005-10-11
3 Chemical and Physical Properties
Molecular Weight 967.1 g/mol
Molecular Formula C46H83N2O17P
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count19
Rotatable Bond Count12
Exact Mass966.54293618 g/mol
Monoisotopic Mass966.54293618 g/mol
Topological Polar Surface Area264 Ų
Heavy Atom Count66
Formal Charge0
Complexity1470
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


FDF Dossiers

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01

Huvepharma

Bulgaria
AACR Annual meeting
Not Confirmed
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Huvepharma

Bulgaria
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AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : To Be Desired

Dosage Form : Granule

Dosage Strength : 100mg/g

Packaging :

Approval Date : 12-08-2009

Application Number : 28104407608

Regulatory Info : Prescription

Registration Country : Denmark

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02

Huvepharma

Bulgaria
AACR Annual meeting
Not Confirmed
arrow

Huvepharma

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : To Be Desired

Dosage Form : Premix

Dosage Strength : 200g/kg

Packaging :

Approval Date : 04-03-2009

Application Number : 28104168507

Regulatory Info : Prescription

Registration Country : Denmark

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03

Huvepharma

Bulgaria
AACR Annual meeting
Not Confirmed
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Huvepharma

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : Tilmovet Vet.

Dosage Form : Concentrate For Oral Solution

Dosage Strength : 250mg/ml

Packaging :

Approval Date : 15-09-2008

Application Number : 28104106107

Regulatory Info : Prescription

Registration Country : Denmark

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04

Huvepharma

Bulgaria
AACR Annual meeting
Not Confirmed
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Huvepharma

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : To Be Desired

Dosage Form : Premix

Dosage Strength : 40g/kg

Packaging :

Approval Date : 04-03-2009

Application Number : 28104181307

Regulatory Info : Prescription

Registration Country : Denmark

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05

Huvepharma

Bulgaria
AACR Annual meeting
Not Confirmed
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Huvepharma

Bulgaria
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AACR Annual meeting
Not Confirmed

TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : TILMOVET PREMIX

Dosage Form : DRUG PREMIX

Dosage Strength : 200G/Kg

Packaging : 1KG/ 5KG/ 10KG/ 20KG

Approval Date :

Application Number : 2349507

Regulatory Info : PRESCRIPTION

Registration Country : Canada

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06

AACR Annual meeting
Not Confirmed
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AACR Annual meeting
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TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : PULMOTIL PREMIX

Dosage Form : DRUG PREMIX

Dosage Strength : 200G/Kg

Packaging : 10KG

Approval Date :

Application Number : 2240124

Regulatory Info : PRESCRIPTION

Registration Country : Canada

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07

AACR Annual meeting
Not Confirmed
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AACR Annual meeting
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TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : PULMOTIL AC

Dosage Form : SOLUTION

Dosage Strength : 250MG/ML

Packaging :

Approval Date :

Application Number : 2393638

Regulatory Info : PRESCRIPTION

Registration Country : Canada

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08

AACR Annual meeting
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AACR Annual meeting
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Tilmicosin phosphate

Brand Name : Tilmico-200

Dosage Form : WSP / Premix

Dosage Strength : 20%

Packaging : 100GM,500GM,1000GM

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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09

AACR Annual meeting
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AACR Annual meeting
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Tilmicosin Phosphate

Brand Name : Tilmotil

Dosage Form : Oral Liquid

Dosage Strength : 250MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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10

Country
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AACR Annual meeting
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Tilmicosin Phosphate

Brand Name : Tilmicosol

Dosage Form : Concentrate For Oral Solution

Dosage Strength : 250mg/ml

Packaging :

Approval Date : 02-02-2011

Application Number : 28104733810

Regulatory Info : Prescription

Registration Country : Denmark

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Europe

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01

Huvepharma Nv

Bulgaria
AACR Annual meeting
Not Confirmed
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Huvepharma Nv

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : To Be Desired

Dosage Form : Granule

Dosage Strength : 100mg/g

Packaging :

Approval Date : 12-08-2009

Application Number : 28104407608

Regulatory Info : Prescription

Registration Country : Denmark

blank

02

Huvepharma Nv

Bulgaria
AACR Annual meeting
Not Confirmed
arrow

Huvepharma Nv

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : To Be Desired

Dosage Form : Premix

Dosage Strength : 200g/kg

Packaging :

Approval Date : 04-03-2009

Application Number : 28104168507

Regulatory Info : Prescription

Registration Country : Denmark

blank

03

Huvepharma Nv

Bulgaria
AACR Annual meeting
Not Confirmed
arrow

Huvepharma Nv

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : Tilmovet Vet.

Dosage Form : Concentrate For Oral Solution

Dosage Strength : 250mg/ml

Packaging :

Approval Date : 15-09-2008

Application Number : 28104106107

Regulatory Info : Prescription

Registration Country : Denmark

blank

04

Huvepharma Nv

Bulgaria
AACR Annual meeting
Not Confirmed
arrow

Huvepharma Nv

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

Tilmicosin Phosphate

Brand Name : To Be Desired

Dosage Form : Premix

Dosage Strength : 40g/kg

Packaging :

Approval Date : 04-03-2009

Application Number : 28104181307

Regulatory Info : Prescription

Registration Country : Denmark

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05

Lavet Pharmaceuticals Ltd.

Country
AACR Annual meeting
Not Confirmed
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Lavet Pharmaceuticals Ltd.

Country
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AACR Annual meeting
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Tilmicosin Phosphate

Brand Name : Tilmicosol

Dosage Form : Concentrate For Oral Solution

Dosage Strength : 250mg/ml

Packaging :

Approval Date : 02-02-2011

Application Number : 28104733810

Regulatory Info : Prescription

Registration Country : Denmark

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06

Pharmaménta Aps

Country
AACR Annual meeting
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Pharmaménta Aps

Country
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AACR Annual meeting
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Tilmicosin Phosphate

Brand Name : To Be Desired

Dosage Form : Concentrate For Oral Solution

Dosage Strength : 250mg/ml

Packaging :

Approval Date : 03-07-2024

Application Number : 28106624921

Regulatory Info : Prescription

Registration Country : Denmark

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Canada

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AACR Annual meeting
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TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : TILMICOSIN 200

Dosage Form : DRUG PREMIX

Dosage Strength : 200G/Kg

Packaging : 10KG

Approval Date :

Application Number : 2461099

Regulatory Info : PRESCRIPTION

Registration Country : Canada

blank

02

HUVEPHARMA EOOD

Bulgaria
AACR Annual meeting
Not Confirmed
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HUVEPHARMA EOOD

Bulgaria
arrow
AACR Annual meeting
Not Confirmed

TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : TILMOVET PREMIX

Dosage Form : DRUG PREMIX

Dosage Strength : 200G/Kg

Packaging : 1KG/ 5KG/ 10KG/ 20KG

Approval Date :

Application Number : 2349507

Regulatory Info : PRESCRIPTION

Registration Country : Canada

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03

AACR Annual meeting
Not Confirmed
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AACR Annual meeting
Not Confirmed

TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : RESPOTIL

Dosage Form : SOLUTION

Dosage Strength : 250MG/ML

Packaging :

Approval Date :

Application Number : 2513811

Regulatory Info : PRESCRIPTION

Registration Country : Canada

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04

AACR Annual meeting
Not Confirmed
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AACR Annual meeting
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TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : PULMOTIL PREMIX

Dosage Form : DRUG PREMIX

Dosage Strength : 200G/Kg

Packaging : 10KG

Approval Date :

Application Number : 2240124

Regulatory Info : PRESCRIPTION

Registration Country : Canada

blank

05

AACR Annual meeting
Not Confirmed
arrow
arrow
AACR Annual meeting
Not Confirmed

TILMICOSIN (TILMICOSIN PHOSPHATE)

Brand Name : PULMOTIL AC

Dosage Form : SOLUTION

Dosage Strength : 250MG/ML

Packaging :

Approval Date :

Application Number : 2393638

Regulatory Info : PRESCRIPTION

Registration Country : Canada

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ABOUT THIS PAGE

Looking for 137330-13-3 / Tilmicosin Phosphate API manufacturers, exporters & distributors?

Tilmicosin Phosphate manufacturers, exporters & distributors 1

14

PharmaCompass offers a list of Tilmicosin Phosphate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Tilmicosin Phosphate manufacturer or Tilmicosin Phosphate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tilmicosin Phosphate manufacturer or Tilmicosin Phosphate supplier.

API | Excipient name

Tilmicosin Phosphate

Synonyms

137330-13-3, Tilmicosin (phosphate), Tilmicosin phosphate [usan], Ly177370 phosphate, Micotil 300, Smh7u1s683

Cas Number

137330-13-3

Unique Ingredient Identifier (UNII)

SMH7U1S683

Tilmicosin Phosphate Manufacturers

A Tilmicosin Phosphate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tilmicosin Phosphate, including repackagers and relabelers. The FDA regulates Tilmicosin Phosphate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tilmicosin Phosphate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Tilmicosin Phosphate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

Tilmicosin Phosphate Suppliers

A Tilmicosin Phosphate supplier is an individual or a company that provides Tilmicosin Phosphate active pharmaceutical ingredient (API) or Tilmicosin Phosphate finished formulations upon request. The Tilmicosin Phosphate suppliers may include Tilmicosin Phosphate API manufacturers, exporters, distributors and traders.

click here to find a list of Tilmicosin Phosphate suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

Tilmicosin Phosphate GMP

Tilmicosin Phosphate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tilmicosin Phosphate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Tilmicosin Phosphate GMP manufacturer or Tilmicosin Phosphate GMP API supplier for your needs.

Tilmicosin Phosphate CoA

A Tilmicosin Phosphate CoA (Certificate of Analysis) is a formal document that attests to Tilmicosin Phosphate's compliance with Tilmicosin Phosphate specifications and serves as a tool for batch-level quality control.

Tilmicosin Phosphate CoA mostly includes findings from lab analyses of a specific batch. For each Tilmicosin Phosphate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tilmicosin Phosphate may be tested according to a variety of international standards, such as European Pharmacopoeia (Tilmicosin Phosphate EP), Tilmicosin Phosphate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tilmicosin Phosphate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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