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Chemistry

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Also known as: 25416-65-3, Levothyroxine sodium, L-thyroxine sodium xhydrate, Levothyroxine sodium hydrate, L-thyroxine sodium hydrate, Monosodium l-thyroxine hydrate
Molecular Formula
C15H12I4NNaO5
Molecular Weight
816.87  g/mol
InChI Key
ANMYAHDLKVNJJO-LTCKWSDVSA-M
FDA UNII
B82379R9W0

Levothyroxine Sodium
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
1 2D Structure

Levothyroxine Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate
2.1.2 InChI
InChI=1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0../s1
2.1.3 InChI Key
ANMYAHDLKVNJJO-LTCKWSDVSA-M
2.1.4 Canonical SMILES
C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.O.[Na+]
2.1.5 Isomeric SMILES
C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)[O-])N.O.[Na+]
2.2 Other Identifiers
2.2.1 UNII
B82379R9W0
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3,5,3',5'-tetraiodothyronine

2. Berlthyrox

3. Dexnon

4. Eferox

5. Eltroxin

6. Eltroxine

7. Euthyrox

8. Eutirox

9. L Thyrox

10. L Thyroxin Beta

11. L Thyroxin Henning

12. L Thyroxine

13. L Thyroxine Roche

14. L-3,5,3',5'-tetraiodothyronine

15. L-thyrox

16. L-thyroxin Beta

17. L-thyroxin Henning

18. L-thyroxine

19. L-thyroxine Roche

20. Lvothyrox

21. Levo T

22. Levo-t

23. Levothroid

24. Levothyroid

25. Levothyroxin Deladande

26. Levothyroxin Delalande

27. Levothyroxine

28. Levothyroxine Sodium

29. Levoxine

30. Levoxyl

31. Novothyral

32. Novothyrox

33. O-(4-hydroxy-3,5-diiodophenyl) 3,5-diiodo-l-tyrosine

34. O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine

35. Oroxine

36. Sodium Levothyroxine

37. Synthroid

38. Synthrox

39. T4 Thyroid Hormone

40. Thevier

41. Thyrax

42. Thyroid Hormone, T4

43. Thyroxin

44. Thyroxine

45. Tiroidine

46. Tiroxina Leo

47. Unithroid

2.3.2 Depositor-Supplied Synonyms

1. 25416-65-3

2. Levothyroxine Sodium

3. L-thyroxine Sodium Xhydrate

4. Levothyroxine Sodium Hydrate

5. L-thyroxine Sodium Hydrate

6. Monosodium L-thyroxine Hydrate

7. 31178-59-3

8. Chebi:6447

9. Levothroid

10. Synthroid

11. Levothyrox

12. Levaxin

13. Levoxyl

14. Oroxine

15. Soloxine

16. Eferox

17. Sodium;(2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate

18. B82379r9w0

19. Thyroxine Sodium

20. Levo-t

21. Liotrix (t4)

22. Thyroxine Sodium Salt

23. L-tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, Monosodium Salt, Monohydrate

24. Latequatro

25. Letequatro

26. Levoroxin

27. Levotiron

28. Tiroxina

29. Tivoral

30. Levo-tiroxina Glaxo

31. Nsc-259940

32. L-tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, Monosodium Salt, Hydrate

33. Unii-b82379r9w0

34. Levothroid (tn)

35. Synthroid (tn)

36. Levoxyl (tn)

37. Levothyroxine Sodium [usp:inn:jan]

38. Starbld0009614

39. L-thyroxin Monosodium Salt

40. T4 (liotrix)

41. Levothyroxine Sodium (usp)

42. Schembl2327406

43. Chembl2103741

44. L-thyroxine Sodium Salt Monohydrate

45. 3,3',5,5'-tetraiodo-l-thyronine Monosodium Salt Hydrate

46. Levothyroxine Sodium Hydrate (jp17)

47. Mfcd06408007

48. Akos015895962

49. Ks-1237

50. D01010

51. E78443

52. Levothyroxine Sodium Monohydrate [who-ip]

53. 3,3',5,5'-tetraiodo-l-thyronine Monosodium Salt

54. A817851

55. Q27107209

56. Levothyroxinum Natricum Monohydrate [who-ip Latin]

57. Sodium 2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate Hydrate

58. Sodium (s)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate Xhydrate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 816.87 g/mol
Molecular Formula C15H12I4NNaO5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass816.6792 g/mol
Monoisotopic Mass816.6792 g/mol
Topological Polar Surface Area96.6 Ų
Heavy Atom Count26
Formal Charge0
Complexity426
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Information
1 of 8  
Drug NameLevo-t
Drug LabelLevothyroxine sodium tablets, USP contains synthetic crystalline L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland.Levothyroxine (T4) sodium has an empir
Active IngredientLevothyroxine sodium
Dosage FormTablet
RouteOral
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 description of spe
Market StatusPrescription
CompanyAlara Pharm

2 of 8  
Drug NameLevothroid
PubMed HealthThyroid Supplement (By mouth)
Drug ClassesDiagnostic Agent, Thyroid Function, Thyroid Supplement
Drug LabelLEVOTHROID (levothyroxine sodium tablets, USP) contains synthetic crystalline L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland. Levothyroxine (T4) sodiu
Active IngredientLevothyroxine sodium
Dosage FormTablet
RouteOral
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 description of spe
Market StatusPrescription
CompanyLloyd

3 of 8  
Drug NameLevothyroxine sodium
Active IngredientLevothyroxine sodium
Dosage FormTablet; Powder; Injectable
Routeinjection; Oral; Intravenous
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 200mcg/vial; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 descr
Market StatusPrescription
CompanyFresenius Kabi Usa; Mylan

4 of 8  
Drug NameLevoxyl
Drug LabelLEVOXYL (levothyroxine sodium tablets, USP) contain synthetic crystalline L-3,3,5,5-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland. Levothyroxine (T4) sodiu...
Active IngredientLevothyroxine sodium
Dosage FormTablet
RouteOral
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 description of spe
Market StatusPrescription
CompanyKing Pharms R And D

5 of 8  
Drug NameLevo-t
Drug LabelLevothyroxine sodium tablets, USP contains synthetic crystalline L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland.Levothyroxine (T4) sodium has an empir
Active IngredientLevothyroxine sodium
Dosage FormTablet
RouteOral
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 description of spe
Market StatusPrescription
CompanyAlara Pharm

6 of 8  
Drug NameLevothroid
PubMed HealthThyroid Supplement (By mouth)
Drug ClassesDiagnostic Agent, Thyroid Function, Thyroid Supplement
Drug LabelLEVOTHROID (levothyroxine sodium tablets, USP) contains synthetic crystalline L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland. Levothyroxine (T4) sodiu
Active IngredientLevothyroxine sodium
Dosage FormTablet
RouteOral
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 description of spe
Market StatusPrescription
CompanyLloyd

7 of 8  
Drug NameLevothyroxine sodium
Active IngredientLevothyroxine sodium
Dosage FormTablet; Powder; Injectable
Routeinjection; Oral; Intravenous
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 200mcg/vial; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 descr
Market StatusPrescription
CompanyFresenius Kabi Usa; Mylan

8 of 8  
Drug NameLevoxyl
Drug LabelLEVOXYL (levothyroxine sodium tablets, USP) contain synthetic crystalline L-3,3,5,5-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland. Levothyroxine (T4) sodiu...
Active IngredientLevothyroxine sodium
Dosage FormTablet
RouteOral
Strength0.05mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.112mg **see current annual edition, 1.8 description of special situations, levothyroxine sodium; 0.2mg **see current annual edition, 1.8 description of spe
Market StatusPrescription
CompanyKing Pharms R And D

5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
l-Thyroxine [EPC]; Thyroxine [CS]
5.2 ATC Code

H - Systemic hormonal preparations, excl. sex hormones and insulins

H03 - Thyroid therapy

H03A - Thyroid preparations

H03AA - Thyroid hormones

H03AA01 - Levothyroxine sodium


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CO.KG","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"ACME GENERICS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"7.17","actualQuantity":"7.17","unit":"KGS","unitRateFc":"4470","totalValueFC":"35526.2","currency":"EUR","unitRateINR":"411463.5","date":"08-Apr-2024","totalValueINR":"2950193.3","totalValueInUsd":"35526.2","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"2936383","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"POST BOX 30 58 40, 20318, HAMBURG ESPLANADE 39, 20354 HAMBURG Hamburg,, GERMANY GERMANY","customerAddress":"PLOT NO 75 INDUSTRIAL AREA PHASE -"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1712860200,"product":"LEVOTHYROXINE SODIUM I.P.","address":"DR ANNIE BESANT ROAD","city":"MUMBAI ,MAHARASHTRA","supplier":"WELDING GMBH & CO.KG","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"GSK","customerCountry":"INDIA","quantity":"35.00","actualQuantity":"35000","unit":"GMS","unitRateFc":"4.9","totalValueFC":"188938","currency":"EUR","unitRateINR":"448.3","date":"12-Apr-2024","totalValueINR":"15689922.5","totalValueInUsd":"188938","indian_port":"Bombay Air","hs_no":"29379090","bill_no":"2992214","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"POSTFACH 30 58 40-20318 ,HAMBURG ESPLANDE 39-20354 HAMBURG GERMANYSDNF Germany","customerAddress":"DR ANNIE BESANT ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713465000,"product":"LEVOTHYROXINE SODIUM MILLED EP\/BP\/IP\/USP\/PH.EUR.","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.51","actualQuantity":"509","unit":"GMS","unitRateFc":"7.2","totalValueFC":"3989.6","currency":"USD","unitRateINR":"650.9","date":"19-Apr-2024","totalValueINR":"331306.51","totalValueInUsd":"3989.6","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3098277","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713465000,"product":"LEVOTHYROXINE SODIUM MILLED EP\/BP\/IP\/USP\/PH.EUR.","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.91","actualQuantity":"1912","unit":"GMS","unitRateFc":"7.2","totalValueFC":"14986.4","currency":"USD","unitRateINR":"650.9","date":"19-Apr-2024","totalValueINR":"1244514.81","totalValueInUsd":"14986.4","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3098277","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713465000,"product":"LEVOTHYROXINE SODIUM MILLED EP\/BP\/IP\/USP\/PH.EUR.","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.55","actualQuantity":"2550","unit":"GMS","unitRateFc":"7.2","totalValueFC":"19987.2","currency":"USD","unitRateINR":"650.9","date":"19-Apr-2024","totalValueINR":"1659787.01","totalValueInUsd":"19987.2","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3098277","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713465000,"product":"LEVOTHYROXINE SODIUM MILLED EP\/BP\/IP\/USP\/PH.EUR.","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"4.00","actualQuantity":"3998","unit":"GMS","unitRateFc":"7.2","totalValueFC":"31336.7","currency":"USD","unitRateINR":"650.9","date":"19-Apr-2024","totalValueINR":"2602285.68","totalValueInUsd":"31336.7","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3098277","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715970600,"product":"LEVOTHYROXINE SODIUM","address":"PLOT NO 75 INDUSTRIAL AREA PHASE -","city":"CHANDIGARH,CHANDIGARH","supplier":"WELDING GMBH & CO.KG","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"ACME GENERICS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"4470","totalValueFC":"99581.3","currency":"EUR","unitRateINR":"413475","date":"18-May-2024","totalValueINR":"8269500","totalValueInUsd":"99581.3","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3548412","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"POST BOX 30 58 40, 20318, HAMBURG ESPLANADE 39, 20354 HAMBURG Hamburg,, GERMANY GERMANY","customerAddress":"PLOT NO 75 INDUSTRIAL AREA PHASE -"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718217000,"product":"LEVOTHYROXINE SODIUM EP\/BP\/IP\/USP\/PH.EUR. (LEVOTHYROXINE SODIUM MILLED 119320)","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.25","actualQuantity":"1246","unit":"GMS","unitRateFc":"7.2","totalValueFC":"9790.1","currency":"USD","unitRateINR":"652.5","date":"13-Jun-2024","totalValueINR":"812995.24","totalValueInUsd":"9790.1","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3981371","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718217000,"product":"LEVOTHYROXINE SODIUM EP\/BP\/IP\/USP\/PH.EUR. (LEVOTHYROXINE SODIUM MILLED 119320)","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.50","actualQuantity":"2499","unit":"GMS","unitRateFc":"7.2","totalValueFC":"19635.2","currency":"USD","unitRateINR":"652.5","date":"13-Jun-2024","totalValueINR":"1630557.87","totalValueInUsd":"19635.2","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3981371","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718217000,"product":"LEVOTHYROXINE SODIUM EP\/BP\/IP\/USP\/PH.EUR. (LEVOTHYROXINE SODIUM MILLED 119320)","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.75","actualQuantity":"2754","unit":"GMS","unitRateFc":"7.2","totalValueFC":"21638.8","currency":"USD","unitRateINR":"652.5","date":"13-Jun-2024","totalValueINR":"1796941.33","totalValueInUsd":"21638.8","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3981371","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718217000,"product":"LEVOTHYROXINE SODIUM EP\/BP\/IP\/USP\/PH.EUR. (LEVOTHYROXINE SODIUM MILLED 119320)","address":"2ND FLOOR, CHINUBHAI CENTRE,","city":"AHMEDABAD, GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"MUNICH","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"4.72","actualQuantity":"4718","unit":"GMS","unitRateFc":"7.2","totalValueFC":"37070.3","currency":"USD","unitRateINR":"652.5","date":"13-Jun-2024","totalValueINR":"3078420.18","totalValueInUsd":"37070.3","indian_port":"Delhi Air","hs_no":"29379090","bill_no":"3981371","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"MUNICH","supplierAddress":"61 SOUTH PARAMUS ROAD,SUITE 565 PARAMUS,NEW JERSEY 07652 UNITED STATES","customerAddress":"2ND FLOOR, CHINUBHAI CENTRE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719599400,"product":"LEVOTHYROXINE SODIUM","address":"564\/A\/22, ROAD NO.92","city":"HYDERABAD,ANDHRA PRADESH","supplier":"WELDING GMBH & CO.KG","supplierCountry":"GERMANY","foreign_port":"FRANKFURT AM MAIN","customer":"VIATRIS","customerCountry":"INDIA","quantity":"80.00","actualQuantity":"80000","unit":"GMS","unitRateFc":"5.7","totalValueFC":"464440.6","currency":"USD","unitRateINR":"482.1","date":"29-Jun-2024","totalValueINR":"38568390","totalValueInUsd":"464440.6","indian_port":"Indore-EPZ\/SEZ","hs_no":"29379090","bill_no":"1004758","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT AM MAIN","supplierAddress":"ESPLANADE 39,D - 20354,HAMBURG,","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720981800,"product":"LEVOTHYROXINE SODIUM ORAL","address":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"SANDOZ B2B","supplierCountry":"AUSTRIA","foreign_port":"LINZ","customer":"MS APL HEALTH ","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2000","unit":"GMS","unitRateFc":"15","totalValueFC":"30508.4","currency":"USD","unitRateINR":"1266.8","date":"15-Jul-2024","totalValueINR":"2533500","totalValueInUsd":"30508.4","indian_port":"APIIC MULTI PRODUCT SEZ NAIDUPET AP","hs_no":"29379090","bill_no":"1001014","productDescription":"API","marketType":"REGULATED MARKET","country":"AUSTRIA","selfForZScoreResived":"Pharma Grade","supplierPort":"LINZ","supplierAddress":"BIOCHEMIESTRASSE 10 6250 GE","customerAddress":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,"}]
11-Jan-2021
31-Aug-2024
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
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(USD/KGS)
Number of Transactions

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Registration Country : Sweden

levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 125 MICROGRAMS

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Registration Country : Sweden

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levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 150 MICROGRAM

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levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 75 MICROGRAMS

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levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 100 MICROGRAMS

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Registration Country : Sweden

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levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 175 MICROGRAMS

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levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 200 MICROGRAM

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levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 50 G

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levothyroxine sodium (hydrate)

Brand Name : Eltroxin

Dosage Form : TABLET

Dosage Strength : 25 MICROGRAMS

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Registration Country : Sweden

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09

26th North American ISSX
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Levothyroxine natricum

Brand Name : Tirosint

Dosage Form : Caps

Dosage Strength : 88mcg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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10

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Levothyroxine natricum

Brand Name : Tirosint Solution

Dosage Form : Sol

Dosage Strength : 150mcg

Packaging :

Approval Date :

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Regulatory Info :

Registration Country : Switzerland

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - TABLET;ORAL - 0.0125MG;0.0031MG

USFDA APPLICATION NUMBER - 16807

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DOSAGE - TABLET;ORAL - 0.025MG;0.0063MG

USFDA APPLICATION NUMBER - 16807

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DOSAGE - TABLET;ORAL - 0.05MG;0.0125MG

USFDA APPLICATION NUMBER - 16807

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DOSAGE - TABLET;ORAL - 0.15MG;0.0375MG

USFDA APPLICATION NUMBER - 16807

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DOSAGE - TABLET;ORAL - 0.1MG;0.025MG

USFDA APPLICATION NUMBER - 16807

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DOSAGE - POWDER;INTRAVENOUS - 100MCG/VIAL

USFDA APPLICATION NUMBER - 202231

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DOSAGE - POWDER;INTRAVENOUS - 200MCG/VIAL

USFDA APPLICATION NUMBER - 202231

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DOSAGE - POWDER;INTRAVENOUS - 500MCG/VIAL

USFDA APPLICATION NUMBER - 202231

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DOSAGE - TABLET;ORAL - 0.025MG **See current ...DOSAGE - TABLET;ORAL - 0.025MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.05MG **See current A...DOSAGE - TABLET;ORAL - 0.05MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.075MG **See current ...DOSAGE - TABLET;ORAL - 0.075MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.088MG **See current ...DOSAGE - TABLET;ORAL - 0.088MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.112MG **See current ...DOSAGE - TABLET;ORAL - 0.112MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.125MG **See current ...DOSAGE - TABLET;ORAL - 0.125MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.137MG **See current ...DOSAGE - TABLET;ORAL - 0.137MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.15MG **See current A...DOSAGE - TABLET;ORAL - 0.15MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.175MG **See current ...DOSAGE - TABLET;ORAL - 0.175MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.1MG **See current An...DOSAGE - TABLET;ORAL - 0.1MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.2MG **See current An...DOSAGE - TABLET;ORAL - 0.2MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.3MG **See current An...DOSAGE - TABLET;ORAL - 0.3MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21116

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DOSAGE - TABLET;ORAL - 0.025MG **See current ...DOSAGE - TABLET;ORAL - 0.025MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.05MG **See current A...DOSAGE - TABLET;ORAL - 0.05MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.075MG **See current ...DOSAGE - TABLET;ORAL - 0.075MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.088MG **See current ...DOSAGE - TABLET;ORAL - 0.088MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.112MG **See current ...DOSAGE - TABLET;ORAL - 0.112MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.125MG **See current ...DOSAGE - TABLET;ORAL - 0.125MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.137MG **See current ...DOSAGE - TABLET;ORAL - 0.137MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.15MG **See current A...DOSAGE - TABLET;ORAL - 0.15MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.175MG **See current ...DOSAGE - TABLET;ORAL - 0.175MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.1MG **See current An...DOSAGE - TABLET;ORAL - 0.1MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.2MG **See current An...DOSAGE - TABLET;ORAL - 0.2MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.3MG **See current An...DOSAGE - TABLET;ORAL - 0.3MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21210

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DOSAGE - TABLET;ORAL - 0.025MG **See current ...DOSAGE - TABLET;ORAL - 0.025MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.05MG **See current A...DOSAGE - TABLET;ORAL - 0.05MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.075MG **See current ...DOSAGE - TABLET;ORAL - 0.075MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.088MG **See current ...DOSAGE - TABLET;ORAL - 0.088MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.112MG **See current ...DOSAGE - TABLET;ORAL - 0.112MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.125MG **See current ...DOSAGE - TABLET;ORAL - 0.125MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.137MG **See current ...DOSAGE - TABLET;ORAL - 0.137MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.15MG **See current A...DOSAGE - TABLET;ORAL - 0.15MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.175MG **See current ...DOSAGE - TABLET;ORAL - 0.175MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.1MG **See current An...DOSAGE - TABLET;ORAL - 0.1MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.2MG **See current An...DOSAGE - TABLET;ORAL - 0.2MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - TABLET;ORAL - 0.3MG **See current An...DOSAGE - TABLET;ORAL - 0.3MG **See current Annual Edition, 1.8 Description of Special Situations, Levothyroxine Sodium

USFDA APPLICATION NUMBER - 21402

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DOSAGE - CAPSULE;ORAL - 0.013MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.025MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.0375MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.044MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.05MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.0625MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.075MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.088MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.112MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.125MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.137MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.15MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.175MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.1MG

USFDA APPLICATION NUMBER - 21924

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DOSAGE - CAPSULE;ORAL - 0.2MG

USFDA APPLICATION NUMBER - 21924

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