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Find Drugs in Development News & Deals for Tetrahydrocannabinol

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  • CAPSULE;ORAL - 10MG
  • CAPSULE;ORAL - 2.5MG
  • CAPSULE;ORAL - 5MG

Details:

Cannabis stimulates two receptors, cannabinoid receptor type 1 (CB1) and type 2 (CB2), within the endocannabinoid system. It is being investigated for multiple indications like post-surgical pain, depressive disorders, chronic headaches, alzheimer's agitation disorder, etc.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: Pink Kush

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 27, 2023

Medipharm CB

Iran Expo

Not Confirmed

envelop Contact Supplier

Details:

Pink Kush (delta-9 tetrahydrocannabinol) is a CB2/CB1 receptor partial agonist, which is approved in combination with Cannabigerol for the treatment of stress, pain and depression.


Lead Product(s): Tetrahydrocannabinol,Cannabigerol

Therapeutic Area: Psychiatry/Psychology Product Name: Pink Kush

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 27, 2023

Medipharm CB

Iran Expo

Not Confirmed

envelop Contact Supplier

Details:

MediPharmto design, manufacture and supply a liquid oral cannabis study drug for the Phase 2 Life’s end Benefits of cannabidiol and tetrahydrocannabinol (LiBBY) study, to be conducted in the U.S., across 20 sites, to treat hospice-eligible patients diagnosed with dementia and agitation.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: T2:C100

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: National Institutes of Health

Deal Size: $16.0 million Upfront Cash: Undisclosed

Deal Type: Funding August 09, 2022

Medipharm CB

Iran Expo

Not Confirmed

envelop Contact Supplier

Details:

Three initial proposed clinical trials will evaluate the effectiveness of proprietary THC and CBD (cannabidiol) drug candidates for multiple indications including Pain, Insomnia associated with Major Depression, and Uremic Pruritus.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: McMaster University

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 21, 2021

Medipharm CB

Iran Expo

Not Confirmed

envelop Contact Supplier

Details:

Patients in Germany are now able to access GMP-certified quality medical cannabis from STADA through local pharmacies under the brand – CannabiSTADA, distributed through STADAPHARM, a direct subsidiary of STADA.


Lead Product(s): Tetrahydrocannabinol,Cannabidiol

Therapeutic Area: Neurology Product Name: CannabiSTADA

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: European Pharmaceutical

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement April 01, 2021

Medipharm CB

Iran Expo

Not Confirmed

envelop Contact Supplier

Details:

As a result of agreement, patients in Germany are now able to access GMP-certified quality medical cannabis from STADA through local pharmacies under the brand – CannabiSTADA (cannabidiol), distributed through STADAPHARM, a direct subsidiary of STADA.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Gastroenterology Product Name: CannabiStada

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: STADA Arzneimittel

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement April 01, 2021

Medipharm CB

Iran Expo

Not Confirmed

envelop Contact Supplier

Details:

IGC-AD1 (tetrahydrocannabinol) is a small molecule drug that targets neuroinflammation and CB1 receptor dysfunction. It is being evaluated for the treatment of alzheimer disease.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: IGC-AD1

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 16, 2024

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The net proceeds will be used for the advancement of company's investigational medicines including IGC-AD1, a natural THC-based oral formulation, as a treatment for agitation in dementia from Alzheimer’s disease.


Lead Product(s): Tetrahydrocannabinol,Melatonin

Therapeutic Area: Neurology Product Name: IGC-AD1

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Bradbury Asset Management

Deal Size: $3.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement March 26, 2024

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The acquisition expands Branded Legacy's portfolio ranging from gummies to compression sleeves and pain-relieving topical creams, including Relief Gummy, which contains a balanced ratio of CBD to Nano Delta-9-THC.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: Relief Gummy

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Branded Legacy, Inc

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition March 12, 2024

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The company is aiming to concentrate on the clinical advancement of THC:CBD (Tetrahydrocannabinol), a partial agonist of the CB1 receptor with Cannabidiol. Both controlled substances will undergo evaluation for the treatment of chemotherapy-induced neuropathic pain.


Lead Product(s): Tetrahydrocannabinol,Cannabidiol

Therapeutic Area: Neurology Product Name: THC:CBD

Highest Development Status: UndisclosedProduct Type: Small molecule

Partner/Sponsor/Collaborator: German Pain Association

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 23, 2024

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IGC-AD1, a combination medicine with a CB1 receptor partial agonist with anti-neuroinflammatory properties. It is under phase 2 clinical development for the treatment of dementia due to Alzheimer’s.


Lead Product(s): Tetrahydrocannabinol,Melatonin

Therapeutic Area: Neurology Product Name: IGC-AD1

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 17, 2024

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The company will use the proceeds for developing its proprietary formulations and pharmaceutical pipeline including, RHO Phyto having diverse range of proprietary formulations including oral, sublingual, topical, and transdermal deliveries with varying ratios of cannabinoids.


Lead Product(s): Cannabidiol,Cannabigerol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: RHO Phyto

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $0.8 million Upfront Cash: Undisclosed

Deal Type: Private Placement December 04, 2023

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Trichomylin softgels, a first-in-class drug product candidate formulated with a proprietary fixed-dose cannabinoid combination, has been specifically designed for the management of chronic pain.


Lead Product(s): Cannabidiol,Cannabichromene,Tetrahydrocannabinol

Therapeutic Area: Musculoskeletal Product Name: Trichomylin

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 21, 2023

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SCI-110 contains dronabinol with the endocannabinoid palmitoylethanolamide. It is developed for Tourette Syndrome to stimulate cannabinoid receptors across the CNS and inhibit the degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 15, 2023

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Details:

SCI-110 contains dronabinol with the endocannabinoid palmitoylethanolamide. It is developed for Tourette Syndrome to stimulate cannabinoid receptors across the CNS and inhibit the degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 10, 2023

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The initial services relate to ResolutionRx’s repurposing of dronabinol and its development program for obstructive sleep apnea pursuant to which Ab Initio will, among other things, manufacture and test the new dronabinol lipid nanoparticle formulation for pharmacokinetic.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: ResolutionRx

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement October 12, 2023

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Details:

SCI-110 contains dronabinol with the endocannabinoid palmitoylethanolamide. It is developed for Tourette Syndrome to stimulate cannabinoid receptors across the CNS and inhibit the degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 07, 2023

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Under the agreement, ResolutionRx will use and exploit the Licensed IP associated with new dronabinol formulations initially to be developed for the treatment of obstructive sleep apnea.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: ResolutionRx

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement August 09, 2023

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The company will use the proceeds for developing its proprietary formulations and pharmaceutical pipeline including, RHO Phyto having diverse range of proprietary formulations including oral, sublingual, topical, and transdermal deliveries with varying ratios of cannabinoids.


Lead Product(s): Cannabidiol,Cannabigerol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: RHO Phyto

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $1.4 million Upfront Cash: Undisclosed

Deal Type: Private Placement August 02, 2023

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IGC-AD1, a low-dose tetrahydrocannabinol based formulation, currently in Phase 2 of clinical trials as a potential treatment for agitation in dementia due to alzheimer’s.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: IGC-AD1

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 02, 2023

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The proceeds will be used for production, raw material and laboratory costs associated with production of GMP cannabinoid medicines CannEpil, a high-CBD, low-THC formulation delivered by an oral mucosal solution and CogniCann, an oral spray that combines THC and CBD.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: CannEpil

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Oberon Capital

Deal Size: $2.6 million Upfront Cash: Undisclosed

Deal Type: Financing August 01, 2023

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Fortrea will manage Incannex's IND opening Phase 2/3 clinical trial investigating IHL-42X which is a synergistic composition of dronabinol, a synthetic form of Tetrahydrocannabinol, and acetazolamide, a carbonic anhydrase inhibitor, for treatment of obstructive sleep apnoea.


Lead Product(s): Acetazolamide,Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: IHL-42X

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Incannex Healthcare

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership July 18, 2023

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The funding will support IGC’s working capital needs primarily related to its Alzheimer’s research, with IGC-AD1, a low-dose tetrahydrocannabinol based formulation, currently in Phase 2 of clinical trials as a potential treatment for agitation in dementia due to Alzheimer’s.


Lead Product(s): Tetrahydrocannabinol,Melatonin

Therapeutic Area: Neurology Product Name: IGC-AD1

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: O-Bank Co., Ltd.

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Financing July 07, 2023

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The funds will support the advancement of the Company’s Phase-2 clinical trial of IGC-AD1 (tetrahydrocannabinol), the Company’s promising investigational drug candidate designed to address agitation in dementia caused by Alzheimer's disease.


Lead Product(s): Tetrahydrocannabinol,Melatonin

Therapeutic Area: Neurology Product Name: IGC-AD1

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Bradbury Asset Management

Deal Size: $3.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement July 06, 2023

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SCI-110 contains dronabinol with the endocannabinoid palmitoylethanolamide. It is developed for Tourette Syndrome to stimulate cannabinoid receptors across the CNS and inhibit the degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Hannover Medical School

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 30, 2023

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SCI-110 contains dronabinol with the endocannabinoid palmitoylethanolamide. It is developed for Tourette Syndrome to stimulate cannabinoid receptors across the CNS and inhibit the degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 21, 2023

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The collaboration aims to focus on Avicanna’s proprietary formulations and pharmaceutical pipeline including, RHO Phyto having diverse range of proprietary formulations including oral, sublingual, topical, and transdermal deliveries with varying ratios of cannabinoids.


Lead Product(s): Cannabidiol,Cannabigerol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: RHO Phyto

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Applied Research Centre at Langara College

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration June 13, 2023

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SBI-100 OE is a novel synthetically-derived molecule formulated as an eye-drop using a propriety nanoemulsion to improve delivery into the eye. It targets the CB1 receptor, which plays a key role in managing intraocular pressure associated with glaucoma.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Ophthalmology Product Name: SBI-100

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 12, 2023

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SCI-110 contains dronabinol with the endocannabinoid palmitoylethanolamide. It is developed for alzheimer's disease and agitation to stimulate cannabinoid receptors across the CNS and inhibit the degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 02, 2023

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Details:

SCI-110 contains dronabinol with the endocannabinoid palmitoylethanolamide. It is developed for alzheimer's disease and agitation to stimulate cannabinoid receptors across the CNS and inhibit the metabolic degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 02, 2023

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The objective of this clinical trial is to evaluate the efficacy, safety and tolerability of SciSparc's proprietary drug candidate SCI-110 (dronabinol) in adult patients (between 18 and 65 years of age) using daily oral treatment.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 04, 2023

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ANEB-001 is a potent, small molecule cannabinoid receptor antagonist, to address the unmet medical need for a specific antidote for acute cannabinoid intoxication.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Psychiatry/Psychology Product Name: ANEB-001

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 28, 2023

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SCI-110 is a unique and proprietary combination of Dronabinol, an FDA-Approved, synthetic version of delta-9-tetrahydrocannabinol, and CannAmide™, the Company's proprietary formulation of Palmitoylethanolamide (PEA).


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 09, 2023

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SCI-110, contains dronabinol with the endocannabinoid palmitoylethanolamide. It is designed to stimulate cannabinoid receptors across the CNS and inhibit the metabolic degradation of endocannabinoids in order to improve uptake of THC.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 06, 2023

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D9-THC (dronabinol, D9-tetrahydrocannabinol) is an oral capsule drug product that is being tested for clinical efficacy in patients with obstructive sleep apnea (OSA).


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: D9-THC

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: University of Illinois

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement January 23, 2023

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Dronabinol, delta-9-THC, is a synthetic version of the naturally occurring substance in the cannabis plant. Drug is an endocannabinoid CB1 and CB2 receptor agonist which is being developed for the treatment of Obstructive sleep apnea.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 12, 2023

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NanaBis™ (tetrahydrocannabinol) is an investigative novel analgesic for cancer patients comprising equal parts of CBD and THC encapsulated in Medlab’s patented delivery platform, NanoCelle®. NanaBis™ is applied to the oro-buccal membrane for rapid uptake.


Lead Product(s): Tetrahydrocannabinol,Cannabidiol

Therapeutic Area: Neurology Product Name: NanaBis

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 12, 2023

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SCI-110 is a unique and proprietary combination of Dronabinol, an FDA-Approved, synthetic version of delta-9-tetrahydrocannabinol, and CannAmide™, the Company's proprietary formulation of Palmitoylethanolamide (PEA).


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: UndisclosedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Soroka Medical Center

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement January 09, 2023

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REDUVO™ is a soft gel capsule used to treat chemotherapy-induced nausea and vomiting (CINV). It is also used to treat weight loss and severe nausea in people living with HIV infection.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Gastroenterology Product Name: Reduvo

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 22, 2022

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The relationship expands Reakiro’s product portfolio from CBD food supplements and cosmetics to include medicinal cannabis products that can be supplied on a prescription basis by pharmacies, clinics, and hospitals globally.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: Estratt

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: A2W Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership November 21, 2022

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REDUVO™ (dronabinol) is a soft gel capsule used to treat chemotherapy-induced nausea and vomiting (CINV). It is also used to treat weight loss and severe nausea in people living with HIV infection.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Gastroenterology Product Name: Reduvo

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 18, 2022

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SCI-110 is a unique and proprietary combination of Dronabinol, an FDA-Approved, synthetic version of delta-9-tetrahydrocannabinol (Δ⁹-THC), and CannAmide™, the Company’s proprietary formulation of Palmitoylethanolamide.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 07, 2022

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This is a phase I Multiple Ascending Dose (MAD) study to evaluate safety and tolerability of IGC-AD1 (tetrahydrocannabinol) in subjects with AD. Twelve subjects will be enrolled. Three different ascending doses of the study product will be given: low, medium and high doses.


Lead Product(s): Tetrahydrocannabinol,Melatonin

Therapeutic Area: Neurology Product Name: IGC-AD1

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 21, 2022

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SBI-100 (tetrahydrocannabinol) OE, a proprietary, synthetic cannabinoid derivative possessing a novel molecular structure and formulation that was rationally designed to enable better penetration of ocular tissue and effective topical delivery of a CB1R agonist.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Ophthalmology Product Name: SBI-100

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 20, 2022

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ABO’s financing facility, to be used at the option of Tetra Bio-Pharma, allows the Company to finance the manufacturing costs of its QIXLEEF (cannabidiol) drug candidate.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: Qixleef

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Alpha Blue Ocean

Deal Size: $7.5 million Upfront Cash: Undisclosed

Deal Type: Financing September 14, 2022

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The company intends to use the net proceeds of the Financing to finance the manufacturing costs of its Qixleef (cannabidiol) drug candidate, to repay indebtedness and for working capital.


Lead Product(s): Cannabidiol,Tetrahydrocannabinol

Therapeutic Area: Neurology Product Name: Qixleef

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Alpha Blue Ocean

Deal Size: $10.0 million Upfront Cash: Undisclosed

Deal Type: Financing September 08, 2022

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RespireRx’s ResolutionRx business unit is developing dronabinol, ∆-9-THC, a synthetic version of the naturally occurring substance in the cannabis plant, for the treatment of OSA.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Sleep Product Name: ResolutionRx

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 08, 2022

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The primary safety objective of the trial will be to assess absolute and relative frequencies of serious adverse events for the entire population and separately for the SCI-110 (dronabinol) and placebo groups.


Lead Product(s): Tetrahydrocannabinol,Palmitoylethanolamide

Therapeutic Area: Neurology Product Name: SCI-110

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Yale University

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement August 01, 2022

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THC stands for Delta-9 tetrahydrocannabinol or tetrahydrocannabinol-9 which is a cannabinoid molecule found in the Cannabis Sativa plant and tends to deliver psychoactive effects- that make people high.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Psychiatry/Psychology Product Name: Delta-9 Gummy

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 01, 2022

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Psilly™ branded functional fungi-based products will be developed by Avicanna utilizing Avicanna’s proprietary delivery systems and scientific platform.


Lead Product(s): Tetrahydrocannabinol,Cannabidiol

Therapeutic Area: Psychiatry/Psychology Product Name: Psilly

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Ei.Ventures

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement July 20, 2022

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