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Technetium Tc 99m

Synopsis, Chemistry

DOSSIERs // Finished Dosage Formulations

1 Dossiers, 1 Canada

DIGITAL CONTENT

2 News

2 News

Also known as: Technetium tc 99m pentetate, Technetium tc 99m pentetate [usp], Techneplex, Vw78417pu1, 65454-61-7, Unii-vw78417pu1

Molecular Formula

C₁₄H₁₈N₃NaO₁₀Tc-₄

Molecular Weight

510.20 g/mol

InChI Key

UBRBVRZQCLXKSZ-FCHARDOESA-I

A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents.

1 2D Structure

Technetium Tc 99m

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;2-[bis[2-[bis(carboxylatomethyl)amino]ethyl]amino]acetate;technetium-99

2.1.2 InChI

InChI=1S/C14H23N3O10.Na.Tc/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;/q;+1;/p-5/i;;1+1

2.1.3 InChI Key

UBRBVRZQCLXKSZ-FCHARDOESA-I

2.1.4 Canonical SMILES

C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Tc]

2.1.5 Isomeric SMILES

C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[99Tc]

2.2 Synonyms

2.2.1 MeSH Synonyms

1. 99m-dtpa, Tc

2. Pentetic Acid, Technetium

3. Tc 99m Dtpa

4. Tc 99m-dtpa

5. Tc-dtpa

6. Technetium (99m) Pentetate

7. Technetium Diethylenetriamine Pentaacetic Acid

8. Technetium Dtpa

9. Technetium Pentetic Acid

10. Technetium Tc 99m Pentetate

11. Technetium-dtpa

2.2.2 Depositor-Supplied Synonyms

1. Technetium Tc 99m Pentetate

2. Technetium Tc 99m Pentetate [usp]

3. Techneplex

4. Vw78417pu1

5. 65454-61-7

6. Unii-vw78417pu1

7. Technetium Tc 99m Pentetate Kit

8. Mpi Tc 99m Dtpa Kit (chelate)

9. Tc 99m Dtpa Kit

10. Tc 99m Dtpa Kit (chelate)

11. Sodium (n,n-bis(2-bis(carboxymethyl)amino)ethyl)glycinato(5-))-technetate(1-)-(sup 99m)tc

12. Human Serum Albumin Diethylenetriaminepentaacetic Acid Technetium((sup 99m)tc) Injection

13. Technetate(1-)-99tc, (n,n-bis(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))-, Sodium

14. Technetate(1-)(sup 99 M)tc, (n,n-bis(2-bis(carboxymethyl)amino)ethyl)glycinato(5-))-, Sodium

15. Technetate(1-)(sup 99m)tc, (n,n-bis(2-bis(carboxymethyl)amino)ethyl)glycinato(5-))-, Sodium

2.3 Create Date

2012-03-21

3 Chemical and Physical Properties

Molecular Formula	C₁₄H₁₈N₃NaO₁₀Tc-₄
Molecular Weight	510.20 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	13
Rotatable Bond Count	0
Exact Mass	509.995238 g/mol
Monoisotopic Mass	509.995238 g/mol
Topological Polar Surface Area	210 Å²
Heavy Atom Count	29
Formal Charge	-4
Complexity	488
Isotope Atom Count	1
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	An-dtpa
PubMed Health	Technetium Tc 99m Pentetate (Injection)
Drug Classes	Diagnostic Agent, Radiopharmaceutical Imaging
Active Ingredient	Technetium tc-99m pentetate kit
Dosage Form	Injectable
Route	Injection
Strength	n/a
Market Status	Prescription
Company	Jubilant Draximage

2 of 2
Drug Name	An-dtpa
PubMed Health	Technetium Tc 99m Pentetate (Injection)
Drug Classes	Diagnostic Agent, Radiopharmaceutical Imaging
Active Ingredient	Technetium tc-99m pentetate kit
Dosage Form	Injectable
Route	Injection
Strength	n/a
Market Status	Prescription
Company	Jubilant Draximage

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Chelating Agents

Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)

Radiopharmaceuticals

Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161) (See all compounds classified as Radiopharmaceuticals.)