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Chemistry

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Also known as: Cc-930, 899805-25-5, Tanzisertib [usan], Cc 930, Chembl1950289, Jnk-930; jnki-1
Molecular Formula
C21H23F3N6O2
Molecular Weight
448.4  g/mol
InChI Key
IBGLGMOPHJQDJB-MOKVOYLWSA-N
FDA UNII
M5O06306UO

Tanzisertib
Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.
1 2D Structure

Tanzisertib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[[9-[(3S)-oxolan-3-yl]-8-(2,4,6-trifluoroanilino)purin-2-yl]amino]cyclohexan-1-ol
2.1.2 InChI
InChI=1S/C21H23F3N6O2/c22-11-7-15(23)18(16(24)8-11)28-21-27-17-9-25-20(26-12-1-3-14(31)4-2-12)29-19(17)30(21)13-5-6-32-10-13/h7-9,12-14,31H,1-6,10H2,(H,27,28)(H,25,26,29)/t12?,13-,14?/m0/s1
2.1.3 InChI Key
IBGLGMOPHJQDJB-MOKVOYLWSA-N
2.1.4 Canonical SMILES
C1CC(CCC1NC2=NC=C3C(=N2)N(C(=N3)NC4=C(C=C(C=C4F)F)F)C5CCOC5)O
2.1.5 Isomeric SMILES
C1COC[C@H]1N2C3=NC(=NC=C3N=C2NC4=C(C=C(C=C4F)F)F)NC5CCC(CC5)O
2.2 Other Identifiers
2.2.1 UNII
M5O06306UO
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (141c)tanzisertib

2. 4-(9-(tetrahydrofuran-3-yl)-8-(2,4,6-trifluorophenylamino)-9h-purin-2-ylamino)cyclohexanol

2.3.2 Depositor-Supplied Synonyms

1. Cc-930

2. 899805-25-5

3. Tanzisertib [usan]

4. Cc 930

5. Chembl1950289

6. Jnk-930; Jnki-1

7. Jnk 930

8. Jnk-930

9. Cc930

10. M5o06306uo

11. Tanzisertib (usan)

12. (1s,4r)-4-((9-((s)-tetrahydrofuran-3-yl)-8-((2,4,6-trifluorophenyl)amino)-9h-purin-2-yl)amino)cyclohexanol

13. Trans-4-((9-((3s)-tetrahydrofuran-3-yl)-8-((2,4,6-trifluorophenyl)amino)-9h-purin-2-yl)amino)cyclohexanol

14. Cyclohexanol, 4-((9-((3s)-tetrahydro-3-furanyl)-8-((2,4,6-trifluorophenyl)amino)-9h-purin-2-yl)amino)-, Trans-

15. Trans-4-({9-[(3s)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9h-purin-2-yl}amino)cyclohexanol

16. Tanzisertib [usan:inn]

17. Unii-m5o06306uo

18. 3tti

19. Cc-930(tanzisertib)

20. Tanzisertib [inn]

21. Gtpl9836

22. Schembl2133055

23. Schembl2133061

24. Schembl4760419

25. Schembl8082102

26. Chembl1950305

27. Schembl10179476

28. Schembl15589918

29. Dtxsid601025671

30. Dtxsid901026042

31. Bcp16541

32. Ex-a3115

33. Bdbm50364378

34. Cc-930cc-930

35. Nsc800943

36. Zb1592

37. Zinc100285204

38. Zinc102930548

39. Compound 1 [pmid: 22244937]

40. Cs-1544

41. Db11798

42. Nsc-800943

43. Ncgc00378972-01

44. Ac-33706

45. Hy-15495

46. Trans-4-((9-((3s)-tetrahydrofuran-3-yl)-8-((2,4,6-trifluorophenyl)amino)-9h-purin-2- Yl)amino)cyclohexanol

47. C77038

48. D10168

49. A900102

50. Q21547222

51. 4-[[9-[(3s)-oxolan-3-yl]-8-(2,4,6-trifluoroanilino)purin-2-yl]amino]cyclohexan-1-ol

52. (1s,4r)-4-((9-((s)-tetrahydrofuran-3-yl)-8-((2,4,6-trifluorophenyl)amino)-9h-purin-2-yl)amino)cyclohexan-1-ol

53. 1629774-47-5

54. 4-[[9-[(3s)-tetrahydro-3-furanyl]-8-[(2,4,6-trifluorophenyl)amino]-9h-purin-2-yl]amino]cyclohexanol

55. Kbi

56. Trans-4-((9-((s)-tetrahydrofuran-3-yl)-8-((2,4,6-trifluorophenyl)amino)-9h-purin-2-yl)amino)cyclohexanol

57. Trans-4-(9-((s)-tetrahydrofuran-3-yl)-8-(2,4,6-trifluorophenylamino)-9h-purin-2-ylamino)cyclohexanol

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 448.4 g/mol
Molecular Formula C21H23F3N6O2
XLogP33.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass448.18345848 g/mol
Monoisotopic Mass448.18345848 g/mol
Topological Polar Surface Area97.1 Ų
Heavy Atom Count32
Formal Charge0
Complexity618
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 899805-25-5 / Tanzisertib API manufacturers, exporters & distributors?

Tanzisertib manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Tanzisertib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Tanzisertib manufacturer or Tanzisertib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Tanzisertib manufacturer or Tanzisertib supplier.

PharmaCompass also assists you with knowing the Tanzisertib API Price utilized in the formulation of products. Tanzisertib API Price is not always fixed or binding as the Tanzisertib Price is obtained through a variety of data sources. The Tanzisertib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Tanzisertib

Synonyms

Cc-930, 899805-25-5, Tanzisertib [usan], Cc 930, Chembl1950289, Jnk-930; jnki-1

Cas Number

899805-25-5

Unique Ingredient Identifier (UNII)

M5O06306UO

About Tanzisertib

Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.

Tanzisertib Manufacturers

A Tanzisertib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Tanzisertib, including repackagers and relabelers. The FDA regulates Tanzisertib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Tanzisertib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Tanzisertib Suppliers

A Tanzisertib supplier is an individual or a company that provides Tanzisertib active pharmaceutical ingredient (API) or Tanzisertib finished formulations upon request. The Tanzisertib suppliers may include Tanzisertib API manufacturers, exporters, distributors and traders.

Tanzisertib GMP

Tanzisertib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Tanzisertib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Tanzisertib GMP manufacturer or Tanzisertib GMP API supplier for your needs.

Tanzisertib CoA

A Tanzisertib CoA (Certificate of Analysis) is a formal document that attests to Tanzisertib's compliance with Tanzisertib specifications and serves as a tool for batch-level quality control.

Tanzisertib CoA mostly includes findings from lab analyses of a specific batch. For each Tanzisertib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Tanzisertib may be tested according to a variety of international standards, such as European Pharmacopoeia (Tanzisertib EP), Tanzisertib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Tanzisertib USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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