Sulfathiazole Sodium

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Also known as: 144-74-1, Sodium sulfathiazole, Sulfathiazole sodium salt, Sulfathiazole (sodium), Pv16n742vm, Sodium norsulfazole

Molecular Formula

C₉H₈N₃NaO₂S₂

Molecular Weight

277.3 g/mol

InChI Key

GWIJGCIVKLITQK-UHFFFAOYSA-N

FDA UNII

PV16N742VM

A sulfathiazole compound that is used as a short-acting anti-infective agent. It is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine.

1 2D Structure

Sulfathiazole Sodium

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;(4-aminophenyl)sulfonyl-(1,3-thiazol-2-yl)azanide

2.1.2 InChI

InChI=1S/C9H8N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2;/q-1;+1

2.1.3 InChI Key

GWIJGCIVKLITQK-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=CC(=CC=C1N)S(=O)(=O)[N-]C2=NC=CS2.[Na+]

2.2 Other Identifiers

2.2.1 UNII

PV16N742VM

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4-amino-n-2-thiazolyl Benzenesulfonamide

2. Alphadol

3. Benzenesulfonamide, 4 Amino N 2 Thiazolyl

4. Benzenesulfonamide, 4-amino-n-2-thiazolyl

5. N(1)-2-thiazolylsulfanilamide

6. Norsulfazole

7. Sulfathiazole

8. Sulfathiazole, Monosodium Salt

2.3.2 Depositor-Supplied Synonyms

1. 144-74-1

2. Sodium Sulfathiazole

3. Sulfathiazole Sodium Salt

4. Sulfathiazole (sodium)

5. Pv16n742vm

6. Sodium Norsulfazole

7. Benzenesulfonamide, 4-amino-n-2-thiazolyl-, Monosodium Salt

8. Sodium;(4-aminophenyl)sulfonyl-(1,3-thiazol-2-yl)azanide

9. Sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide

10. Sodium Sulphathiazole

11. Soluble Sulfathiazole

12. Sodium 2-sulfanilamidothiazole

13. Monosodium 2-sulfanilamidothiazole

14. 2-sulfanilamidothiazole Sodium Salt

15. Einecs 205-638-5

16. Sulfathiazole Sodium [nf]

17. Unii-pv16n742vm

18. Soluthiazomide

19. Ai3-26815

20. N(sup 1)-2-thiazolylsulfanilamide Sodium Salt

21. Sodium, (n(sup 1)-2-thiazolylsulfanilamido)-

22. Mfcd00072133

23. Sulphathiazole Sodium

24. 4-amino-n-(2-thiazolyl)benzenesulfonamide Sodium Salt

25. Sulfathiazole Sodium 5h2o

26. Dsstox_cid_30279

27. Dsstox_gsid_51724

28. Schembl1639401

29. Chembl2107243

30. Dtxsid6051724

31. Sulfanilamide, N(sup 1)-2-thiazolyl-, Monosodium Salt

32. Hy-b0507a

33. Sulfathiazole Sodium Salt, >=99%

34. Bcp13309

35. Sulfanilamide, N(sup 1)-2-thiazolyl-, N(sup 1)-sodium Deriv.

36. Tox21_303846

37. S5963

38. Stk177341

39. Sulfathiazole Sodium [mart.]

40. Sulfathiazole Sodium [who-dd]

41. Akos005410678

42. Akos024307512

43. Akos032953796

44. S12091

45. Ncgc00357116-01

46. (n(sup1)-2-thiazolylsulfanilamido)-sodiu

47. As-82169

48. Cas-144-74-1

49. Db-042746

50. Ft-0631837

51. N-(2-thiazolyl)-n-sodio-4-aminobenzenesulfonamide

52. Sodium (4-aminophenylsulfonyl)(thiazol-2-yl)amide

53. Sr-01000883699

54. Sodium((4-aminophenyl)sulfonyl)(thiazol-2-yl)amide

55. Sr-01000883699-1

56. W-108149

57. Q27286771

58. Sodium ((4-aminophenyl)sulfonyl)(thiazol-2-yl)amide

59. Benzenesulfonamide, 4-amino-n-2-thiazolyl-, Sodium Salt (1:1)

2.4 Create Date

2007-02-07

3 Chemical and Physical Properties

Molecular Formula	C₉H₈N₃NaO₂S₂
Molecular Weight	277.3 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	276.99556314 g/mol
Monoisotopic Mass	276.99556314 g/mol
Topological Polar Surface Area	111 Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	326
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)