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    Also known as: 69388-84-7, Sulbactam sodium salt, Sodium sulbactam, Combactam, Sulbactam (sodium), Sulbactam (as sodium)
    Molecular Formula
    C8H10NNaO5S
    Molecular Weight
    255.23  g/mol
    InChI Key
    NKZMPZCWBSWAOX-IBTYICNHSA-M
    FDA UNII
    DKQ4T82YE6
    Sulbactam Sodium
    A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
    1 2D Structure

    Sulbactam Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;(2S,5R)-3,3-dimethyl-4,4,7-trioxo-46-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
    2.1.2 InChI
    InChI=1S/C8H11NO5S.Na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6H,3H2,1-2H3,(H,11,12);/q;+1/p-1/t5-,6+;/m1./s1
    2.1.3 InChI Key
    NKZMPZCWBSWAOX-IBTYICNHSA-M
    2.1.4 Canonical SMILES
    CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])C.[Na+]
    2.1.5 Isomeric SMILES
    CC1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])C.[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    DKQ4T82YE6
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Btamaze

    2. Combactam

    3. Cp 45899

    4. Cp-45899

    5. Cp45899

    6. Penicillanic Acid Sulfone

    7. Sodium, Sulbactam

    8. Sulbactam

    9. Sulfone, Penicillanic Acid

    2.3.2 Depositor-Supplied Synonyms

    1. 69388-84-7

    2. Sulbactam Sodium Salt

    3. Sodium Sulbactam

    4. Combactam

    5. Sulbactam (sodium)

    6. Sulbactam (as Sodium)

    7. Dkq4t82ye6

    8. Sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

    9. Sodium;(2s,5r)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

    10. Cp-45899-2

    11. Cp-45,899-2

    12. Sodium 1,1-dioxopenicillanate

    13. Cp-458992

    14. Sulbactam Sodium (unasyn)

    15. Sodium Penicillanate 1,1-dioxide

    16. Sulbactam Natrium

    17. Cp 45899 Sodium Salt

    18. Penicillanic Acid Dioxide Sodium Salt

    19. Penicillanic Acid Sulfone Sodium Salt

    20. Unii-dkq4t82ye6

    21. Cp 45899-2

    22. Sulbactam Sodium [usan:usp:jan]

    23. Sodium (2s,5r)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate 4,4-dioxide

    24. Sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate 4,4-dioxide

    25. Einecs 273-984-4

    26. Cp 45899 Sodium

    27. Penicillanic Acid 1,1-dioxide Sodium Salt

    28. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, Sodium Salt, (2s,5r)- (9ci)

    29. Schembl667857

    30. Sulbactam Sodium [jan]

    31. Sulbactam Sodium (jp17/usp)

    32. Sulbactam Sodium [usan]

    33. Chembl1200944

    34. Sulbactam Sodium [vandf]

    35. Hy-b0334a

    36. Sulbactam Sodium [mart.]

    37. Chebi:157785

    38. Sulbactam Sodium [who-dd]

    39. Dtxsid401026661

    40. Hms3651h07

    41. Sulbactam Sodium Salt [mi]

    42. Akos015963378

    43. Sulbactam Sodium [ep Impurity]

    44. Sulbactam Sodium [orange Book]

    45. Ccg-267009

    46. Sulbactam Sodium [ep Monograph]

    47. Sulbactam Sodium [usp Impurity]

    48. Sulbactam Sodium [usp Monograph]

    49. Ac-20083

    50. Cs-0013161

    51. S2551

    52. Sulperazone Component Sulbactam Sodium

    53. D02223

    54. Sulbactam Sodium Component Of Sulperazone

    55. W-104633

    56. Q27276453

    57. Sulbactam Sodium, Antibiotic For Culture Media Use Only

    58. (2s,5r)-3,3-dimethyl-4,4,7-trioxo-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

    59. (2s,5r)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide Sodium Salt

    60. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, Sodium Salt, (2s-cis)-

    61. Sodium(2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate4,4-dioxide

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 255.23 g/mol
    Molecular Formula C8H10NNaO5S
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count1
    Exact Mass255.01773788 g/mol
    Monoisotopic Mass255.01773788 g/mol
    Topological Polar Surface Area103 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity452
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    beta-Lactamase Inhibitors

    Endogenous substances and drugs that inhibit or block the activity of BETA-LACTAMASES. (See all compounds classified as beta-Lactamase Inhibitors.)

    API Reference Price

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    02-Jan-2021
    29-Aug-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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