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Chemistry

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Also known as: 69388-79-0, Sulbactam pivoxyl, Pivsulbactam, Sulbactam pivoxil [usan], Cp-47904, Unii-2x0wta96kx
Molecular Formula
C14H21NO7S
Molecular Weight
347.39  g/mol
InChI Key
OHPVYKXTRACOSQ-ZJUUUORDSA-N
FDA UNII
2X0WTA96KX

Sulbactam Pivoxil
Sulbactam Pivoxil is the pivoxil prodrug form of sulbactam, a semi-synthetic beta-lactamase inhibitor, with beta-lactam antibiotic adjuvant activity. After oral administration of sulbactam pivoxil, the ester bond is cleaved, releasing active sulbactam. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme.
1 2D Structure

Sulbactam Pivoxil

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2,2-dimethylpropanoyloxymethyl (2S,5R)-3,3-dimethyl-4,4,7-trioxo-46-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
2.1.2 InChI
InChI=1S/C14H21NO7S/c1-13(2,3)12(18)22-7-21-11(17)10-14(4,5)23(19,20)9-6-8(16)15(9)10/h9-10H,6-7H2,1-5H3/t9-,10+/m1/s1
2.1.3 InChI Key
OHPVYKXTRACOSQ-ZJUUUORDSA-N
2.2 Other Identifiers
2.2.1 UNII
2X0WTA96KX
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cp 47,904

2. Cp-47,904

3. Cp-47904

4. Sulbactam Pivoxyl

2.3.2 Depositor-Supplied Synonyms

1. 69388-79-0

2. Sulbactam Pivoxyl

3. Pivsulbactam

4. Sulbactam Pivoxil [usan]

5. Cp-47904

6. Unii-2x0wta96kx

7. Pivoxil Sulbactam

8. Sulbactam Pivoxil (usan)

9. 2x0wta96kx

10. Pivsulbactam [mart.]

11. Pivsulbactam [who-dd]

12. Cp-47,904

13. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid,3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl Ester,4,4-dioxide, (2s,5r)-

14. Pivsulbactam (mart.)

15. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2,2-dimethyl-1-oxopropoxy)methyl Ester, (2s-cis)-

16. Hydroxymethyl (2s,5r)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate Pivalate (ester), 4,4-dioxide

17. (2s,5r)-(pivaloyloxy)methyl 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

18. Cp 47904; Unasyn Oral

19. Cp 47904

20. (pivaloyloxy)methyl Penicillanate S,s-dioxide

21. Schembl635112

22. Chembl423875

23. Chebi:135467

24. Mfcd00867003

25. Akos025310138

26. As-13808

27. Cp 47,904

28. Hy-108288

29. Cs-0028149

30. D03706

31. E75950

32. Q27255724

33. (2s,5r)-(pivaloyloxy)methyl3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate4,4-dioxide

34. (pivaloyloxy)methyl (2s,5r)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

35. 2,2-dimethylpropanoyloxymethyl (2s,5r)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

36. 2,2-dimethylpropanoyloxymethyl 3,3-dimethyl-4,4,7-trioxo-4

37. E6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 347.39 g/mol
Molecular Formula C14H21NO7S
XLogP30.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area115
Heavy Atom Count23
Formal Charge0
Complexity654
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 69388-79-0 / Sulbactam Pivoxil API manufacturers, exporters & distributors?

Sulbactam Pivoxil manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Sulbactam Pivoxil API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sulbactam Pivoxil manufacturer or Sulbactam Pivoxil supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sulbactam Pivoxil manufacturer or Sulbactam Pivoxil supplier.

PharmaCompass also assists you with knowing the Sulbactam Pivoxil API Price utilized in the formulation of products. Sulbactam Pivoxil API Price is not always fixed or binding as the Sulbactam Pivoxil Price is obtained through a variety of data sources. The Sulbactam Pivoxil Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Sulbactam Pivoxil

Synonyms

69388-79-0, Sulbactam pivoxyl, Pivsulbactam, Sulbactam pivoxil [usan], Cp-47904, Unii-2x0wta96kx

Cas Number

69388-79-0

Unique Ingredient Identifier (UNII)

2X0WTA96KX

About Sulbactam Pivoxil

Sulbactam Pivoxil is the pivoxil prodrug form of sulbactam, a semi-synthetic beta-lactamase inhibitor, with beta-lactam antibiotic adjuvant activity. After oral administration of sulbactam pivoxil, the ester bond is cleaved, releasing active sulbactam. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme.

Sulbactam Pivoxil Manufacturers

A Sulbactam Pivoxil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sulbactam Pivoxil, including repackagers and relabelers. The FDA regulates Sulbactam Pivoxil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sulbactam Pivoxil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sulbactam Pivoxil manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sulbactam Pivoxil Suppliers

A Sulbactam Pivoxil supplier is an individual or a company that provides Sulbactam Pivoxil active pharmaceutical ingredient (API) or Sulbactam Pivoxil finished formulations upon request. The Sulbactam Pivoxil suppliers may include Sulbactam Pivoxil API manufacturers, exporters, distributors and traders.

click here to find a list of Sulbactam Pivoxil suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sulbactam Pivoxil GMP

Sulbactam Pivoxil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sulbactam Pivoxil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sulbactam Pivoxil GMP manufacturer or Sulbactam Pivoxil GMP API supplier for your needs.

Sulbactam Pivoxil CoA

A Sulbactam Pivoxil CoA (Certificate of Analysis) is a formal document that attests to Sulbactam Pivoxil's compliance with Sulbactam Pivoxil specifications and serves as a tool for batch-level quality control.

Sulbactam Pivoxil CoA mostly includes findings from lab analyses of a specific batch. For each Sulbactam Pivoxil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sulbactam Pivoxil may be tested according to a variety of international standards, such as European Pharmacopoeia (Sulbactam Pivoxil EP), Sulbactam Pivoxil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sulbactam Pivoxil USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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