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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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API Suppliers

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USDMF

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CEP/COS

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JDMF

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EU WC

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KDMF

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NDC API

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VMF

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Listed Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

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FDA Orange Book

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Europe

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Canada

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Australia

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South Africa

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DRUG PRODUCT COMPOSITIONS

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PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Regulatory FDF Prices

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API

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Chemistry

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Also known as: 1268454-23-4, Mln1117, Mln-1117, Ink1117, Ink-1117, Agn-pc-0db6fl
Molecular Formula
C19H17N5O3
Molecular Weight
363.4  g/mol
InChI Key
BLGWHBSBBJNKJO-UHFFFAOYSA-N
FDA UNII
43J9Q56T3W

Serabelisib
an investigational PI3Kalpha-selective inhibitor
1 2D Structure

Serabelisib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[6-(2-amino-1,3-benzoxazol-5-yl)imidazo[1,2-a]pyridin-3-yl]-morpholin-4-ylmethanone
2.1.2 InChI
InChI=1S/C19H17N5O3/c20-19-22-14-9-12(1-3-16(14)27-19)13-2-4-17-21-10-15(24(17)11-13)18(25)23-5-7-26-8-6-23/h1-4,9-11H,5-8H2,(H2,20,22)
2.1.3 InChI Key
BLGWHBSBBJNKJO-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
43J9Q56T3W
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (6-(2-amino-1,3-benzoxazol-5-yl)imidazo(1,2-a)pyridin-3-yl)(4-morpholinyl)methanone

2. Tak-117

3. Ink1117

4. Mln1117

2.3.2 Depositor-Supplied Synonyms

1. 1268454-23-4

2. Mln1117

3. Mln-1117

4. Ink1117

5. Ink-1117

6. Agn-pc-0db6fl

7. Tak-117

8. [6-(2-amino-1,3-benzoxazol-5-yl)imidazo[1,2-a]pyridin-3-yl]-morpholin-4-ylmethanone

9. Methanone, [6-(2-amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinyl-

10. 43j9q56t3w

11. 5-[3-(morpholine-4-carbonyl)imidazo[1,2-a]pyridin-6-yl]-1,3-benzoxazol-2-amine

12. (6-(2-amino-5-benzoxazolyl)imidazo(1,2-a)pyridin-3-yl)-4-morpholinylmethanone

13. Methanone, (6-(2-amino-5-benzoxazolyl)imidazo(1,2-a)pyridin-3-yl)-4-morpholinyl-

14. (6-(2-amino-1,3-benzoxazol-5-yl)imidazo(1,2-a)pyridin-3-yl)(4-morpholinyl)methanone

15. Serabelisibum

16. (6-(2-amino-1,3-benzoxazol-5-yl)imidazo(1,2-a)pyridin-3-yl)-morpholin-4-ylmethanone

17. [6-(2-amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinylmethanone

18. 5-(3-(morpholine-4-carbonyl)imidazo(1,2-a)pyridin-6-yl)-1,3-benzoxazol-2-amine

19. Refchem:182491

20. Tak 117

21. (6-(2-aminobenzo[d]oxazol-5-yl)imidazo[1,2-a]pyridin-3-yl)(morpholino)methanone

22. Serabelisib [inn]

23. Mfcd15146372

24. Mln 1117

25. [6-(2-amino-1,3-benzoxazol-5-yl)imidazo[1,2-a]pyridin-3-yl]-morpholino-methanone

26. [6-(2-amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinyl-methanone

27. Unii-43j9q56t3w

28. C19h17n5o3

29. Serabelisib [who-dd]

30. Gtpl8969

31. Orb1304485

32. Chembl3935857

33. Schembl12928418

34. Schembl29382156

35. Bdbm119531

36. Ex-a1112

37. Ink 1117

38. Mln1117; Ink1117

39. Nsc795384

40. S8581

41. Akos030526373

42. Ccg-268203

43. Cs-5490

44. Db14935

45. Ebc-520105

46. Nsc-795384

47. 1428967-74-1

48. Ac-33667

49. As-73722

50. Hy-12285

51. Db-084944

52. Ink-1117,mln-1117,tak-117

53. Serabelisib(tak-117,ink1117,mln1117)

54. Serabelisib(tak-117,ink1117,mln1117)?

55. Us9682141, 54

56. Serabelisib (ink-1117,mln-1117,tak-117)

57. Us9682141, 529

58. Brd-k73877023-001-01-9

59. Q27078071

2.4 Create Date
2013-03-21
3 Chemical and Physical Properties
Molecular Weight 363.4 g/mol
Molecular Formula C19H17N5O3
XLogP32.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area98.9
Heavy Atom Count27
Formal Charge0
Complexity557
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.


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API | Excipient name

Serabelisib

Synonyms

1268454-23-4, Mln1117, Mln-1117, Ink1117, Ink-1117, Agn-pc-0db6fl

Cas Number

1268454-23-4

Unique Ingredient Identifier (UNII)

43J9Q56T3W

About Serabelisib

an investigational PI3Kalpha-selective inhibitor

Serabelisib Manufacturers

A Serabelisib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Serabelisib, including repackagers and relabelers. The FDA regulates Serabelisib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Serabelisib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Serabelisib Suppliers

A Serabelisib supplier is an individual or a company that provides Serabelisib active pharmaceutical ingredient (API) or Serabelisib finished formulations upon request. The Serabelisib suppliers may include Serabelisib API manufacturers, exporters, distributors and traders.

Serabelisib GMP

Serabelisib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Serabelisib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Serabelisib GMP manufacturer or Serabelisib GMP API supplier for your needs.

Serabelisib CoA

A Serabelisib CoA (Certificate of Analysis) is a formal document that attests to Serabelisib's compliance with Serabelisib specifications and serves as a tool for batch-level quality control.

Serabelisib CoA mostly includes findings from lab analyses of a specific batch. For each Serabelisib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Serabelisib may be tested according to a variety of international standards, such as European Pharmacopoeia (Serabelisib EP), Serabelisib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Serabelisib USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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