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Also known as: Nn9535, Ozempic, Rybelsus, 910463-68-2, Nn 9535, Nnc 0113-0217
Molecular Formula
C187H291N45O59
Molecular Weight
4114  g/mol
InChI Key
DLSWIYLPEUIQAV-CCUURXOWSA-N

Semaglutide
1 2D Structure

Semaglutide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
18-[[(1R)-4-[2-[2-[2-[2-[2-[2-[[(5S)-5-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-2-methylpropanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-5-oxopentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[2-[[(2S)-5-carbamimidamido-1-(carboxymethylamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-6-oxohexyl]amino]-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-1-carboxy-4-oxobutyl]amino]-18-oxooctadecanoic acid
2.1.2 InChI
InChI=1S/C187H291N45O59/c1-18-105(10)154(180(282)208-108(13)159(261)216-133(86-114-89-200-119-50-40-39-49-117(114)119)170(272)218-129(82-102(4)5)171(273)228-152(103(6)7)178(280)215-121(53-44-72-199-186(192)193)162(264)201-91-141(242)209-120(52-43-71-198-185(190)191)161(263)204-94-151(257)258)230-172(274)131(83-111-45-33-31-34-46-111)219-167(269)126(64-69-149(253)254)214-166(268)122(51-41-42-70-195-144(245)98-290-79-78-289-76-74-197-145(246)99-291-80-77-288-75-73-196-139(240)66-61-127(183(285)286)211-140(241)54-37-29-27-25-23-21-19-20-22-24-26-28-30-38-55-146(247)248)212-158(260)107(12)206-157(259)106(11)207-165(267)125(60-65-138(189)239)210-142(243)92-202-163(265)123(62-67-147(249)250)213-168(270)128(81-101(2)3)217-169(271)130(85-113-56-58-116(238)59-57-113)220-175(277)135(95-233)223-177(279)137(97-235)224-179(281)153(104(8)9)229-174(276)134(88-150(255)256)221-176(278)136(96-234)225-182(284)156(110(15)237)231-173(275)132(84-112-47-35-32-36-48-112)222-181(283)155(109(14)236)227-143(244)93-203-164(266)124(63-68-148(251)252)226-184(287)187(16,17)232-160(262)118(188)87-115-90-194-100-205-115/h31-36,39-40,45-50,56-59,89-90,100-110,118,120-137,152-156,200,233-238H,18-30,37-38,41-44,51-55,60-88,91-99,188H2,1-17H3,(H2,189,239)(H,194,205)(H,195,245)(H,196,240)(H,197,246)(H,201,264)(H,202,265)(H,203,266)(H,204,263)(H,206,259)(H,207,267)(H,208,282)(H,209,242)(H,210,243)(H,211,241)(H,212,260)(H,213,270)(H,214,268)(H,215,280)(H,216,261)(H,217,271)(H,218,272)(H,219,269)(H,220,277)(H,221,278)(H,222,283)(H,223,279)(H,224,281)(H,225,284)(H,226,287)(H,227,244)(H,228,273)(H,229,276)(H,230,274)(H,231,275)(H,232,262)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,285,286)(H4,190,191,198)(H4,192,193,199)/t105-,106-,107-,108-,109+,110+,118-,120-,121-,122-,123-,124-,125-,126-,127+,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,152-,153-,154-,155-,156-/m0/s1
2.1.3 InChI Key
DLSWIYLPEUIQAV-CCUURXOWSA-N
2.1.4 Canonical SMILES
CCC(C)C(C(=O)NC(C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(C)(C)NC(=O)C(CC6=CN=CN6)N
2.1.5 Isomeric SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](CC6=CN=CN6)N
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Ozempic

2. Rybelsus

2.2.2 Depositor-Supplied Synonyms

1. Nn9535

2. Ozempic

3. Rybelsus

4. 910463-68-2

5. Nn 9535

6. Nnc 0113-0217

7. Nn-9535

8. Unii-53axn4nnhx

9. Semaglutide [usan:inn]

10. Wegovy

11. 53axn4nnhx

12. Rybelsus (oral Semaglutide)

13. Gtpl9724

14. Ozempic (injectable Semaglutide)

15. Chebi:167574

16. Ex-a2424

17. Ac-32580

18. Nnc-0113-0217

19. Rybelsus;ozempic;nn9535;og217sc;nnc 0113-0217

2.3 Create Date
2012-03-21
3 Chemical and Physical Properties
Molecular Weight 4114 g/mol
Molecular Formula C187H291N45O59
XLogP3-5.8
Hydrogen Bond Donor Count57
Hydrogen Bond Acceptor Count63
Rotatable Bond Count151
Exact Mass4112.1187318 g/mol
Monoisotopic Mass4111.1153770 g/mol
Topological Polar Surface Area1650 Ų
Heavy Atom Count291
Formal Charge0
Complexity9590
Isotope Atom Count0
Defined Atom Stereocenter Count30
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise:

- as monotherapy when metformin is considered inappropriate due to intolerance or contraindications;

- in addition to other medicinal products for the treatment of diabetes.

For study results with respect to combinations, effects on glycaemic control and cardiovascular events, and the populations studied, see sections 4. 4, 4. 5 and 5. 1.


Treatment of obesity


Treatment of type II diabetes mellitus


Rybelsus is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus to improve glycaemic control as an adjunct to diet and exercise

- as monotherapy when metformin is considered inappropriate due to intolerance or contraindications

- in combination with other medicinal products for the treatment of diabetes.

For study results with respect to combinations, effects on glycaemic control and cardiovascular events, and the populations studied, see sections 4. 4, 4. 5 and 5. 1.


Treatment of type II diabetes mellitus


Wegovy is indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in adults with an initial Body Mass Index (BMI) of

- 30 kg/m (obesity), or

- 27 kg/m to < 30 kg/m (overweight) in the presence of at least one weight-related comorbidity e. g. dysglycaemia (prediabetes or type 2 diabetes mellitus), hypertension, dyslipidaemia, obstructive sleep apnoea or cardiovascular disease.


5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Glucagon-Like Peptide 1 [CS]; Glucagon-like Peptide-1 (GLP-1) Agonists [MoA]; GLP-1 Receptor Agonist [EPC]
5.2 ATC Code

A10BJ06


A10BJ06


A10BJ06


A - Alimentary tract and metabolism

A10 - Drugs used in diabetes

A10B - Blood glucose lowering drugs, excl. insulins

A10BJ - Glucagon-like peptide-1 (glp-1) analogues

A10BJ06 - Semaglutide


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ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1767983400,"product":"SEMAGLUTIDE SEMAGLUTIDE R & D PURPOSE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL JIANGDONG","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"DR REDDY'S LABORATORIES","customerCountry":"INDIA","quantity":"0.03","actualQuantity":"0.028","unit":"KGS","unitRateFc":"170000","totalValueFC":"4763.4","currency":"USD","unitRateINR":"15436000","date":"10-Jan-2026","totalValueINR":"432208","totalValueInUsd":"4763.4","indian_port":"Bangalore Air","hs_no":"29371900","bill_no":"346","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"CO LTD NO.7278 MEILIN AVENUE, DAJIA NGDONG INDUSTRIAL CLUSTER ZONE HANG ZHOU 311228 Shanghai Pu Dong Apt, , CHINA","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1767983400,"product":"SEMAGLUTIDE [FOR TESTING PURPOSE] SEMAGLUTIDE [FOR TESTING PURPOSE]","address":"NO S 26 BOMMASANDRA INDUSTRIAL ARE","city":"BANGALORE,KARNATAKA","supplier":"LUNA CHEMICALS CO LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ALTHERA LABORATORIES INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"62076.8","totalValueFC":"6212.1","currency":"USD","unitRateINR":"5636577.4","date":"10-Jan-2026","totalValueINR":"563657.74","totalValueInUsd":"6212.1","indian_port":"Bangalore Air","hs_no":"29371900","bill_no":"1","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"FLOOR 11TH,CBD HANGZHOU YIN, 2030 J IANGHUI ROAD,HANGZHOU,ZHEJIANG,CHIN A China","customerAddress":"NO S 26 BOMMASANDRA INDUSTRIAL ARE"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1768242600,"product":"SEMAGLUTIDE SEMAGLUTIDE","address":"TORRENT HOUSE,","city":"AHMEDABAD. GUJARAT","supplier":"M\/S.CHENGDU SHENGNUO BIOPHARM CO. LTD.","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"TORRENT PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"0.26","actualQuantity":"260","unit":"GMS","unitRateFc":"157.7","totalValueFC":"41029","currency":"USD","unitRateINR":"14318.5","date":"13-Jan-2026","totalValueINR":"3722800","totalValueInUsd":"41029","indian_port":"Bombay Air","hs_no":"29371900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO.258, SECTION 1, XUESHAN AVENUE, QINGXIA STREET, DAYI COUNTY, CHENGD U, SICHUAN CHINA","customerAddress":"TORRENT HOUSE,"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1768242600,"product":"SEMAGLUTIDE BATCH NO 10332250102B SEMAGLUTIDE BATCH NO 10332250102B","address":"L\/204, MANTRI WOODLANDS, B.G. ROAD,","city":"KARNATAKA STATE","supplier":"SINOPEPALLSINO BIOPHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"INSTAPILL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"409.7","totalValueFC":"41000.4","currency":"N\/A","unitRateINR":"37202.1","date":"13-Jan-2026","totalValueINR":"3720205.71","totalValueInUsd":"41000.4","indian_port":"Bangalore Air","hs_no":"29371900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO 28, LINPU ROAD, ECONOMIC & TECHN OLOGICAL DEVELOPMENT ZONE LIANYUNGA NG, JIANGSU, PROVINCE CHINA, , Chin China","customerAddress":"L\/204, MANTRI WOODLANDS, B.G. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1768761000,"product":"SEMAGLUTIDE(SAMPLE FOC SHIPMENT) SEMAGLUTIDE(SAMPLE FOC SHIPMENT)","address":"KRISLON HOUSE, SAKI VIHAR ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"SUZHOU BIOSYNERGY PHARMACEUTICAL CO.,LTD.","supplierCountry":"CHINA","foreign_port":"CHENGDU","customer":"EVONIK INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"0.01","unit":"KGS","unitRateFc":"180000","totalValueFC":"1809.2","currency":"N\/A","unitRateINR":"16416000","date":"19-Jan-2026","totalValueINR":"164160","totalValueInUsd":"1809.2","indian_port":"Bombay Air","hs_no":"29371900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHENGDU","supplierAddress":"ROOM L5002-101, VANGUARD PARK BRANC H, 172 JINLIANG STREET, SUZHOU INDU STRIAL PARK, JIANGSU, CHINA China","customerAddress":"KRISLON HOUSE, SAKI VIHAR ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1768847400,"product":"SEMAGLUTIDE API(BATCH NO: 10332250102B)","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"SINOPEP-ALLSINO BIOPHARMACEUTIC AL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI PU DONG APT","customer":"DR REDDY'S LABORATORIES","customerCountry":"INDIA","quantity":"0.19","actualQuantity":"192","unit":"GMS","unitRateFc":"253.9","totalValueFC":"48994.6","currency":"USD","unitRateINR":"23154","date":"20-Jan-2026","totalValueINR":"4445568","totalValueInUsd":"48994.6","indian_port":"Vizag-EPZ\/SEZ","hs_no":"29371900","bill_no":"412","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI PU DONG APT","supplierAddress":"NO.28 LINPU ROAD LIANYUNGANG INDUST AREA ECO TECH DEVELOPMENT ZONE SDNF China","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1769020200,"product":"SEMAGLUTIDE SEMAGLUTIDE","address":"NO 31, RACE COURSE ROAD,BANGALORE","city":"BENGALURU,KARNATAKA","supplier":"SINOPEP ALLSINO BIOPHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"MICRO LABS LTD","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"10","unit":"GMS","unitRateFc":"650","totalValueFC":"6533.2","currency":"N\/A","unitRateINR":"59280","date":"22-Jan-2026","totalValueINR":"592800","totalValueInUsd":"6533.2","indian_port":"Madras Air","hs_no":"29371900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO. 28 LINPU ROAD LIANYUNGANG INDUSTRIAL AREA ECO & TECH DEVELOPMENT ZONE, JIANGSU CHINA","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"}]
04-Feb-2022
30-Jan-2026
KGS
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Quantity (KGS) & Unit rate (USD/KGS) over time

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Drugs in Development

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Details:

Semaglutide, a peptide targeting GLP-1 receptor, shows promise in weight loss, offering a potential breakthrough in obesity treatment.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Nutrition and Weight Loss Brand Name: Wegovy-Generic

Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable October 24, 2025

Dr Reddy Company Banner

01

Lead Product(s) : Semaglutide,Inapplicable

Therapeutic Area : Nutrition and Weight Loss

Highest Development Status : Approved FDF

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Semaglutide, a peptide targeting GLP-1 receptor, shows promise in weight loss, offering a potential breakthrough in obesity treatment.

Product Name : Wegovy-Generic

Product Type : Peptide, Unconjugated

Upfront Cash : Inapplicable

October 24, 2025

Dr Reddy Company Banner

Details:

Semaglutide is a GLP-1 receptor agonist, which is being investigated in Phase 3 for the treatment of weight loss type 2 diabetes and chronic kidney disease.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Nutrition and Weight Loss Brand Name: Semaglutide-Generic

Study Phase: Phase IIIProduct Type: Peptide, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable October 19, 2023

Dr Reddy Company Banner

02

Lead Product(s) : Semaglutide,Inapplicable

Therapeutic Area : Nutrition and Weight Loss

Highest Development Status : Phase III

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Semaglutide is a GLP-1 receptor agonist, which is being investigated in Phase 3 for the treatment of weight loss type 2 diabetes and chronic kidney disease.

Product Name : Semaglutide-Generic

Product Type : Peptide, Unconjugated

Upfront Cash : Inapplicable

October 19, 2023

Dr Reddy Company Banner

Details:

subcutaneous semaglutide is a GLP-1 receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adults.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Nutrition and Weight Loss Brand Name: Semaglutide-Generic

Study Phase: Phase IIIProduct Type: Peptide, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable October 18, 2023

Dr Reddy Company Banner

03

Lead Product(s) : Semaglutide,Inapplicable

Therapeutic Area : Nutrition and Weight Loss

Highest Development Status : Phase III

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : subcutaneous semaglutide is a GLP-1 receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adults.

Product Name : Semaglutide-Generic

Product Type : Peptide, Unconjugated

Upfront Cash : Inapplicable

October 18, 2023

Dr Reddy Company Banner

Details:

The collaboration aims to advance type 2 diabetes treatment through the development of Semaglutide, an unconjugated peptide targeting the GLP-1 receptor.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Endocrinology Brand Name: Extensior

Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

Sponsor: Abbott Laboratories

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration February 27, 2026

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04

Novo Nordisk

Denmark
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BioProcess International US West
Not Confirmed

Novo Nordisk

Denmark
arrow
BioProcess International US West
Not Confirmed

Details : The collaboration aims to advance type 2 diabetes treatment through the development of Semaglutide, an unconjugated peptide targeting the GLP-1 receptor.

Product Name : Extensior

Product Type : Peptide, Unconjugated

Upfront Cash : Undisclosed

February 27, 2026

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Details:

Semaglutide, a peptide targeting GLP-1 receptor, shows promise in treating Type 2 diabetes.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Endocrinology Brand Name: Semaglyn

Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 26, 2026

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05

BioProcess International US West
Not Confirmed
BioProcess International US West
Not Confirmed

Details : Semaglutide, a peptide targeting GLP-1 receptor, shows promise in treating Type 2 diabetes.

Product Name : Semaglyn

Product Type : Peptide, Unconjugated

Upfront Cash : Inapplicable

February 26, 2026

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Details:

The collaboration aims to advance Semaglutide, an unconjugated peptide targeting the GLP-1 receptor, for the treatment of Type 2 diabetes.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Endocrinology Brand Name: Undisclosed

Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

Sponsor: Natco Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration February 24, 2026

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06

BioProcess International US West
Not Confirmed
BioProcess International US West
Not Confirmed

Details : The collaboration aims to advance Semaglutide, an unconjugated peptide targeting the GLP-1 receptor, for the treatment of Type 2 diabetes.

Product Name : Undisclosed

Product Type : Peptide, Unconjugated

Upfront Cash : Undisclosed

February 24, 2026

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Details:

NPM-139 (Semaglutide) is a peptide drug, which is currently being evaluated in Phase I clinical studies for the treatment of obesity.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Nutrition and Weight Loss Brand Name: NPM-139

Study Phase: Phase IProduct Type: Peptide, Unconjugated

Sponsor: Avance Clinical

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 24, 2026

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07

BioProcess International US West
Not Confirmed
BioProcess International US West
Not Confirmed

Details : NPM-139 (Semaglutide) is a peptide drug, which is currently being evaluated in Phase I clinical studies for the treatment of obesity.

Product Name : NPM-139

Product Type : Peptide, Unconjugated

Upfront Cash : Inapplicable

February 24, 2026

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Details:

The peptide-based, unconjugated lead product targets GLP-1R for the treatment of type 2 diabetes.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Endocrinology Brand Name: Semaglutide-Generic

Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 15, 2026

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08

Natco Pharma

India
arrow
BioProcess International US West
Not Confirmed

Natco Pharma

India
arrow
BioProcess International US West
Not Confirmed

Details : The peptide-based, unconjugated lead product targets GLP-1R for the treatment of type 2 diabetes.

Product Name : Semaglutide-Generic

Product Type : Peptide, Unconjugated

Upfront Cash : Inapplicable

February 15, 2026

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Details:

BIO101 (20-Hydroxyecdysone) is a small molecule drug, which is currently being evaluated in Phase II clinical studies for the treatment of cachexia.


Lead Product(s): 20-Hydroxyecdysone,Semaglutide

Therapeutic Area: Nutrition and Weight Loss Brand Name: BIO101

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 13, 2026

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09

Biophytis

France
arrow
BioProcess International US West
Not Confirmed

Biophytis

France
arrow
BioProcess International US West
Not Confirmed

Details : BIO101 (20-Hydroxyecdysone) is a small molecule drug, which is currently being evaluated in Phase II clinical studies for the treatment of cachexia.

Product Name : BIO101

Product Type : Miscellaneous

Upfront Cash : Inapplicable

February 13, 2026

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  • Development Update

Details:

Semaglutide is a peptide drug, which is currently being evaluated in Approved FDF clinical studies for the treatment of obesity.


Lead Product(s): Semaglutide,Inapplicable

Therapeutic Area: Nutrition and Weight Loss Brand Name: Undisclosed

Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 05, 2026

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10

Hims & Hers

Country
arrow
BioProcess International US West
Not Confirmed

Hims & Hers

Country
arrow
BioProcess International US West
Not Confirmed

Details : Semaglutide is a peptide drug, which is currently being evaluated in Approved FDF clinical studies for the treatment of obesity.

Product Name : Undisclosed

Product Type : Peptide, Unconjugated

Upfront Cash : Inapplicable

February 05, 2026

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INTERMEDIATE SUPPLIERS

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothShanghai Minbiotech is the leading producer of biopharmaceuticals and a variety of high-end generic & innovative drugs.

CAS Number : 2061897-68-3

End Use API : Semaglutide

About The Company : Shanghai Minbiotech is specializing in the R&D and production of advanced pharmaceutical intermediates and biological APIs. There are more than 1000 square mete...

Shanghai Minbiotech CB

02

BioProcess International US West
Not Confirmed
arrow
BioProcess International US West
Not Confirmed
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CAS Number : 1143516-05-5

End Use API : Semaglutide

About The Company : CongenPharma, founded in 2013 and headquartered in Guangzhou, is a leading manufacturer of pharmaceutical peptide intermediates, cosmetic peptides, and ingredie...

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03

BioProcess International US West
Not Confirmed
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BioProcess International US West
Not Confirmed
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CAS Number : 843666-40-0

End Use API : Semaglutide

About The Company : CongenPharma, founded in 2013 and headquartered in Guangzhou, is a leading manufacturer of pharmaceutical peptide intermediates, cosmetic peptides, and ingredie...

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04

BioProcess International US West
Not Confirmed
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BioProcess International US West
Not Confirmed
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CAS Number : 2061897-68-3

End Use API : Semaglutide

About The Company : CongenPharma, founded in 2013 and headquartered in Guangzhou, is a leading manufacturer of pharmaceutical peptide intermediates, cosmetic peptides, and ingredie...

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05

BioProcess International US West
Not Confirmed
arrow
BioProcess International US West
Not Confirmed
arrow

CAS Number : 1890228-73-5

End Use API : Semaglutide

About The Company : CongenPharma, founded in 2013 and headquartered in Guangzhou, is a leading manufacturer of pharmaceutical peptide intermediates, cosmetic peptides, and ingredie...

blank

06

BioProcess International US West
Not Confirmed
arrow
BioProcess International US West
Not Confirmed
arrow

CAS Number : 1118767-16-0

End Use API : Semaglutide

About The Company : CongenPharma, founded in 2013 and headquartered in Guangzhou, is a leading manufacturer of pharmaceutical peptide intermediates, cosmetic peptides, and ingredie...

blank

07

BioProcess International US West
Not Confirmed
arrow
BioProcess International US West
Not Confirmed
arrow

CAS Number : 1662688-20-1

End Use API : Semaglutide

About The Company : CongenPharma, founded in 2013 and headquartered in Guangzhou, is a leading manufacturer of pharmaceutical peptide intermediates, cosmetic peptides, and ingredie...

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08

LinkChem

China
BioProcess International US West
Not Confirmed
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LinkChem

China
BioProcess International US West
Not Confirmed
arrow

CAS Number : 134979-01-4

End Use API : Semaglutide

About The Company : LinkChem is a leading China headquartered CMO | CRO provider within the pharmaceutical industry. Our core focus includes: custom synthesis, process development,...

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09

LinkChem

China
BioProcess International US West
Not Confirmed
arrow

LinkChem

China
BioProcess International US West
Not Confirmed
arrow

CAS Number : 1143516-05-5

End Use API : Semaglutide

About The Company : LinkChem is a leading China headquartered CMO | CRO provider within the pharmaceutical industry. Our core focus includes: custom synthesis, process development,...

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10

LinkChem

China
BioProcess International US West
Not Confirmed
arrow

LinkChem

China
BioProcess International US West
Not Confirmed
arrow

CAS Number : 1069067-08-8

End Use API : Semaglutide

About The Company : LinkChem is a leading China headquartered CMO | CRO provider within the pharmaceutical industry. Our core focus includes: custom synthesis, process development,...

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FDF Dossiers

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01

Pharmathen SA

Greece
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

Flag Greece
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Regulatory Info : USA

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 3MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : USA

Registration Country : Greece

Pharmathen

02

Pharmathen SA

Greece
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

Flag Greece
Digital Content Digital Content

Regulatory Info : USA

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 7MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : USA

Registration Country : Greece

Pharmathen

03

Pharmathen SA

Greece
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

Flag Greece
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Regulatory Info : USA

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 14MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : USA

Registration Country : Greece

Pharmathen

04

Pharmathen SA

Greece
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

Flag Greece
Digital Content Digital Content

Regulatory Info : USA

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Injection For Subcutaneous Use

Dosage Strength : 2MG/1.5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info : USA

Registration Country : Greece

Pharmathen

05

Pharmathen SA

Greece
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

Flag Greece
Digital Content Digital Content

Regulatory Info :

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Solution For Injection

Dosage Strength : 2MG/1.5ML

Packaging : Pre-filled Pen

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Greece

Pharmathen

06

Pharmathen SA

Greece
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

Flag Greece
Digital Content Digital Content

Regulatory Info :

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Solution For Injection

Dosage Strength : 4MG/3ML

Packaging : Pre-filled Pen

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Greece

Pharmathen

07

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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Digital Content Digital Content

Regulatory Info :

Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 0.25MG/0.5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

08

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 0.5MG/0.5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

09

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 1MG/0.5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya

10

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSupriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 1.7MG/0.75ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Supriya
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DRUG PRODUCT COMPOSITIONS

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DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/3ML (0.6...DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/3ML (0.68MG/ML)

USFDA APPLICATION NUMBER - 209637

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DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/1.5ML (1...DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/1.5ML (1.34MG/ML)

USFDA APPLICATION NUMBER - 209637

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DOSAGE - SOLUTION;SUBCUTANEOUS - 4MG/3ML (1.3...DOSAGE - SOLUTION;SUBCUTANEOUS - 4MG/3ML (1.34MG/ML)

USFDA APPLICATION NUMBER - 209637

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DOSAGE - SOLUTION;SUBCUTANEOUS - 8MG/3ML (2.6...DOSAGE - SOLUTION;SUBCUTANEOUS - 8MG/3ML (2.68MG/ML)

USFDA APPLICATION NUMBER - 209637

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ABOUT THIS PAGE

Looking for 910463-68-2 / Semaglutide API manufacturers, exporters & distributors?

Semaglutide manufacturers, exporters & distributors 1

35

PharmaCompass offers a list of Semaglutide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Semaglutide manufacturer or Semaglutide supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Semaglutide manufacturer or Semaglutide supplier.

PharmaCompass also assists you with knowing the Semaglutide API Price utilized in the formulation of products. Semaglutide API Price is not always fixed or binding as the Semaglutide Price is obtained through a variety of data sources. The Semaglutide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Semaglutide

Synonyms

Nn9535, Ozempic, Rybelsus, 910463-68-2, Nn 9535, Nnc 0113-0217

Cas Number

910463-68-2

Semaglutide [USAN:INN] Manufacturers

A Semaglutide [USAN:INN] manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Semaglutide [USAN:INN], including repackagers and relabelers. The FDA regulates Semaglutide [USAN:INN] manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Semaglutide [USAN:INN] API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Semaglutide [USAN:INN] manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Semaglutide [USAN:INN] Suppliers

A Semaglutide [USAN:INN] supplier is an individual or a company that provides Semaglutide [USAN:INN] active pharmaceutical ingredient (API) or Semaglutide [USAN:INN] finished formulations upon request. The Semaglutide [USAN:INN] suppliers may include Semaglutide [USAN:INN] API manufacturers, exporters, distributors and traders.

click here to find a list of Semaglutide [USAN:INN] suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Semaglutide [USAN:INN] USDMF

A Semaglutide [USAN:INN] DMF (Drug Master File) is a document detailing the whole manufacturing process of Semaglutide [USAN:INN] active pharmaceutical ingredient (API) in detail. Different forms of Semaglutide [USAN:INN] DMFs exist exist since differing nations have different regulations, such as Semaglutide [USAN:INN] USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Semaglutide [USAN:INN] DMF submitted to regulatory agencies in the US is known as a USDMF. Semaglutide [USAN:INN] USDMF includes data on Semaglutide [USAN:INN]'s chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Semaglutide [USAN:INN] USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Semaglutide [USAN:INN] suppliers with USDMF on PharmaCompass.

Semaglutide [USAN:INN] KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Semaglutide [USAN:INN] Drug Master File in Korea (Semaglutide [USAN:INN] KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Semaglutide [USAN:INN]. The MFDS reviews the Semaglutide [USAN:INN] KDMF as part of the drug registration process and uses the information provided in the Semaglutide [USAN:INN] KDMF to evaluate the safety and efficacy of the drug.

After submitting a Semaglutide [USAN:INN] KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Semaglutide [USAN:INN] API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Semaglutide [USAN:INN] suppliers with KDMF on PharmaCompass.

Semaglutide [USAN:INN] WC

A Semaglutide [USAN:INN] written confirmation (Semaglutide [USAN:INN] WC) is an official document issued by a regulatory agency to a Semaglutide [USAN:INN] manufacturer, verifying that the manufacturing facility of a Semaglutide [USAN:INN] active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Semaglutide [USAN:INN] APIs or Semaglutide [USAN:INN] finished pharmaceutical products to another nation, regulatory agencies frequently require a Semaglutide [USAN:INN] WC (written confirmation) as part of the regulatory process.

click here to find a list of Semaglutide [USAN:INN] suppliers with Written Confirmation (WC) on PharmaCompass.

Semaglutide [USAN:INN] NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Semaglutide [USAN:INN] as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Semaglutide [USAN:INN] API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Semaglutide [USAN:INN] as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Semaglutide [USAN:INN] and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Semaglutide [USAN:INN] NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Semaglutide [USAN:INN] suppliers with NDC on PharmaCompass.

Semaglutide [USAN:INN] GMP

Semaglutide [USAN:INN] Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Semaglutide [USAN:INN] GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Semaglutide [USAN:INN] GMP manufacturer or Semaglutide [USAN:INN] GMP API supplier for your needs.

Semaglutide [USAN:INN] CoA

A Semaglutide [USAN:INN] CoA (Certificate of Analysis) is a formal document that attests to Semaglutide [USAN:INN]'s compliance with Semaglutide [USAN:INN] specifications and serves as a tool for batch-level quality control.

Semaglutide [USAN:INN] CoA mostly includes findings from lab analyses of a specific batch. For each Semaglutide [USAN:INN] CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Semaglutide [USAN:INN] may be tested according to a variety of international standards, such as European Pharmacopoeia (Semaglutide [USAN:INN] EP), Semaglutide [USAN:INN] JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Semaglutide [USAN:INN] USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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