Saxagliptin Hydrochloride

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

17 API Suppliers, 12 USDMF, 8 EU WC, 5 NDC API, 7 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Imports

INTERMEDIATES

2 Suppliers

2 Suppliers

DOSSIERs // Finished Dosage Formulations

41 Dossiers, 30 FDA Orange Book, 2 Europe, 9 Canada

DRUG PRODUCT COMPOSITION

TABLET, EXTENDED RELEASE;ORAL - 1GM;EQ 2.5MG BASE, TABLET, EXTENDED RELEASE;ORAL - 1GM;EQ 5MG BASE, TABLET, EXTENDED RELEASE;ORAL - 500MG;EQ 5MG BASE, TABLET;ORAL - EQ 2.5MG BASE, TABLET;ORAL - EQ 5MG BASE

TABLET, EXTENDED RELEASE;ORAL - 1GM;EQ 2.5MG BASE
TABLET, EXTENDED RELEASE;ORAL - 1GM;EQ 5MG BASE
TABLET, EXTENDED RELEASE;ORAL - 500MG;EQ 5MG BASE
TABLET;ORAL - EQ 2.5MG BASE
TABLET;ORAL - EQ 5MG BASE

RELATED EXCIPIENT COMPANIES

Suppliers, 26 Kerry, 13 Microlex e.U, 11 Sigachi Industries, 10 Roquette, 8 Gangwal Healthcare, 7 Gangwal Chemicals, 6 DFE Pharma, 5 Corel Pharma Chem, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 3 Ideal Cures Pvt Ltd, 3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 3 Vasa Pharmachem, 3 Prachin Chemical, 2 Nanjing Well Pharmaceutical, 1 The Dow Chemical Company, 1 Pharmatrans-Sanaq, 1 DKSH, 1 Jai Radhe Sales, 1 Kima Chemical, 1 Rochem International Inc, 1 Clariant, 1 Aeon Procare, 1 Ingredion Pharma Solutions, 1 BASF, 1 SPI Pharma

EXCIPIENTS BY APPLICATIONS

46 Fillers, Diluents & Binders, 20 Coating Systems & Additives, 19 Direct Compression, 18 Disintegrants & Superdisintegrants, 15 Thickeners and Stabilizers, 13 Lubricants & Glidants, 11 Granulation, 10 Co-Processed Excipients, 9 Controlled & Modified Release, 6 Film Formers & Plasticizers, 5 Rheology Modifiers, 3 Parenteral, 3 Taste Masking, 3 Solubilizers, 3 Topical, 2 API Stability Enhancers, 2 Emulsifying Agents, 2 Chewable & Orodispersible Aids, 1 Surfactant & Foaming Agents

GLOBAL SALES INFORMATION

8 US Medicaid Prescriptions

8 US Medicaid Prescriptions

MARKET PLACE

1 APIs

1 APIs

PATENTS

50 US Patents, 4 US Exclusivities, 4 Health Canada Patents

DIGITAL CONTENT

2 Data Compilations & Company Tracker #PharmaFlow, 12 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

18,227

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

1,716.00

Annual Reports

820.00

FDF Market Place

EXCIPIENTS

116

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 709031-78-7

Molecular Formula

C₁₈H₂₆ClN₃O₂

Molecular Weight

351.9 g/mol

InChI Key

TUAZNHHHYVBVBR-RIKNOMPASA-N

1 2D Structure

Saxagliptin Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(1R,3R)-2-[(2R)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;hydrochloride

2.1.2 InChI

InChI=1S/C18H25N3O2.ClH/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H/t10?,11?,12?,13-,14-,15+,17?,18?;/m1./s1

2.1.3 InChI Key

TUAZNHHHYVBVBR-RIKNOMPASA-N

2.1.4 Canonical SMILES

C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N.Cl

2.1.5 Isomeric SMILES

C1[C@@H](N([C@H]2C1C2)C(=O)[C@@H](C34CC5CC(C3)CC(C5)(C4)O)N)C#N.Cl

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. 709031-78-7

2.3 Create Date

2012-03-21

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₂₆ClN₃O₂
Molecular Weight	351.9 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	351.1713548 g/mol
Monoisotopic Mass	351.1713548 g/mol
Topological Polar Surface Area	90.4 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	609
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	3
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

Find Saxagliptin Hydrochloride manufacturers, exporters & distributors on PharmaCompass

Saxagliptin Hydrochloride

Saxagliptin Hydrochloride

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

17 API Suppliers

12 USDMF

8 EU WC

5 NDC API

7 Listed Suppliers

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Imports

INTERMEDIATES

2 Suppliers

DOSSIERs // Finished Dosage Formulations

41 Dossiers

30 FDA Orange Book

2 Europe

9 Canada

DRUG PRODUCT COMPOSITION

TABLET, EXTENDED RELEASE;ORAL - 1GM;EQ 2.5MG BASE

TABLET, EXTENDED RELEASE;ORAL - 1GM;EQ 5MG BASE

TABLET, EXTENDED RELEASE;ORAL - 500MG;EQ 5MG BASE

TABLET;ORAL - EQ 2.5MG BASE

TABLET;ORAL - EQ 5MG BASE

RELATED EXCIPIENT COMPANIES

Suppliers

26 Kerry

13 Microlex e.U

11 Sigachi Industries

10 Roquette

8 Gangwal Healthcare

7 Gangwal Chemicals

6 DFE Pharma

5 Corel Pharma Chem

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

3 Ideal Cures Pvt Ltd

3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

3 Vasa Pharmachem

3 Prachin Chemical

2 Nanjing Well Pharmaceutical

1 The Dow Chemical Company

1 Pharmatrans-Sanaq

1 DKSH

1 Jai Radhe Sales

1 Kima Chemical

1 Rochem International Inc

1 Clariant

1 Aeon Procare

1 Ingredion Pharma Solutions

1 BASF

1 SPI Pharma

EXCIPIENTS BY APPLICATIONS

46 Fillers, Diluents & Binders

20 Coating Systems & Additives

19 Direct Compression

18 Disintegrants & Superdisintegrants

15 Thickeners and Stabilizers

13 Lubricants & Glidants

11 Granulation

10 Co-Processed Excipients

9 Controlled & Modified Release

6 Film Formers & Plasticizers

5 Rheology Modifiers

3 Parenteral

3 Taste Masking

3 Solubilizers

3 Topical

2 API Stability Enhancers

2 Emulsifying Agents

2 Chewable & Orodispersible Aids

1 Surfactant & Foaming Agents

GLOBAL SALES INFORMATION

8 US Medicaid Prescriptions

MARKET PLACE

1 APIs