Find Rostaporfin manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Tin ethyl etiopurpurin, Purlytin, Snet2, Rostaporfin [mi], Rostaporfin [inn], Rostaporfin [usan]
Molecular Formula
C37H42Cl2N4O2Sn-4
Molecular Weight
764.4  g/mol
InChI Key
XRJWACZWBZYJTB-HQTZEDFWSA-K
FDA UNII
466G63QE7G

Rostaporfin
Tin Ethyl Etiopurpurin is a synthetic purpurin with photosensitizing activity. Tin ethyl etiopurpurin preferentially accumulates in tumor cells due to an increased rate of metabolism. Upon exposure to a light source, this agent absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen with local cytotoxic effects. (NCI04)
1 2D Structure

Rostaporfin

2 Identification
2.1 Computed Descriptors
2.1.1 InChI
InChI=1S/C37H43N4O2.2ClH.Sn/c1-10-23-19(6)29-17-33-25(12-3)21(8)34(40-33)26-15-27(36(42)43-14-5)37(13-4)22(9)30(41-35(26)37)18-32-24(11-2)20(7)28(39-32)16-31(23)38-29;;;/h15-18,22H,10-14H2,1-9H3,(H-,38,39,40,41,42);2*1H;/q-1;;;/p-3/t22-,37-;;;/m1.../s1
2.1.2 InChI Key
XRJWACZWBZYJTB-HQTZEDFWSA-K
2.2 Other Identifiers
2.2.1 UNII
466G63QE7G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Etiopurpurin, Tin

2. Snet2

3. Tin Etiopurpurin

4. Tin Etiopurpurin Dichloride

2.3.2 Depositor-Supplied Synonyms

1. Tin Ethyl Etiopurpurin

2. Purlytin

3. Snet2

4. Rostaporfin [mi]

5. Rostaporfin [inn]

6. Rostaporfin [usan]

7. Snet-2

8. Rostaporfin [mart.]

9. 466g63qe7g

10. (oc-6-13)-dichloro(rel-ethyl(18r,19s)-3,4,20,21-tetradehydro-4,9,14,19-tetraethyl-18,19-dihydro-3,8,13,18-tetramethyl-20-phorbinecarboxylato(2-)-.kappa.n(sup 23), .kappa.n(sup 24), .kappa.n(sup 25), .kappa.n(sup 26))tin

11. Tin, Dichloro(rel-ethyl (18r,19s)-3,4,20,21-tetradehydro-4,9,14,19-tetraethyl-18,19-dihydro-3,8,13,18-tetramethyl-20-phorbinecarboxylato(2-)-.kappa.n23,.kappa.n24,.kappa.n25,.kappa.n26)-, (oc-6-13)-

12. Tin, Dichloro(rel-ethyl(18r,19s)-3,4,20,21-tetradehydro-4,9,14,19-tetraethyl-18,19-dihydro-3,8,13,18-tetramethyl-20-phorbinecarboxylato(2-)-.kappa.-n(sup 23),-.kappa.-n(sup 24),-.kappa.-n(sup 25),-.kappa.-n(sup 26))-, (oc-6-13)-

2.4 Create Date
2021-02-16
3 Chemical and Physical Properties
Molecular Weight 764.4 g/mol
Molecular Formula C37H42Cl2N4O2Sn-4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area54.1
Heavy Atom Count46
Formal Charge-4
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count4
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Photosensitizing Agents

Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms. (See all compounds classified as Photosensitizing Agents.)


Radiation-Sensitizing Agents

Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells. (See all compounds classified as Radiation-Sensitizing Agents.)


ABOUT THIS PAGE

Looking for 284041-10-7 / Rostaporfin API manufacturers, exporters & distributors?

Rostaporfin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Rostaporfin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Rostaporfin manufacturer or Rostaporfin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Rostaporfin manufacturer or Rostaporfin supplier.

PharmaCompass also assists you with knowing the Rostaporfin API Price utilized in the formulation of products. Rostaporfin API Price is not always fixed or binding as the Rostaporfin Price is obtained through a variety of data sources. The Rostaporfin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Rostaporfin

Synonyms

Tin ethyl etiopurpurin, Purlytin, Snet2, Rostaporfin [mi], Rostaporfin [inn], Rostaporfin [usan]

Cas Number

284041-10-7

Unique Ingredient Identifier (UNII)

466G63QE7G

About Rostaporfin

Tin Ethyl Etiopurpurin is a synthetic purpurin with photosensitizing activity. Tin ethyl etiopurpurin preferentially accumulates in tumor cells due to an increased rate of metabolism. Upon exposure to a light source, this agent absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen with local cytotoxic effects. (NCI04)

Rostaporfin Manufacturers

A Rostaporfin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Rostaporfin, including repackagers and relabelers. The FDA regulates Rostaporfin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Rostaporfin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Rostaporfin Suppliers

A Rostaporfin supplier is an individual or a company that provides Rostaporfin active pharmaceutical ingredient (API) or Rostaporfin finished formulations upon request. The Rostaporfin suppliers may include Rostaporfin API manufacturers, exporters, distributors and traders.

Rostaporfin GMP

Rostaporfin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Rostaporfin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Rostaporfin GMP manufacturer or Rostaporfin GMP API supplier for your needs.

Rostaporfin CoA

A Rostaporfin CoA (Certificate of Analysis) is a formal document that attests to Rostaporfin's compliance with Rostaporfin specifications and serves as a tool for batch-level quality control.

Rostaporfin CoA mostly includes findings from lab analyses of a specific batch. For each Rostaporfin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Rostaporfin may be tested according to a variety of international standards, such as European Pharmacopoeia (Rostaporfin EP), Rostaporfin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Rostaporfin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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