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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

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Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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FINISHED DOSAGE FORMULATIONS

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Europe

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Canada

Canada

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Australia

Australia

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South Africa

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Listed Dossiers

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FDF Dossiers

DRUG PRODUCT COMPOSITIONS

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0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

API REF. PRICE (USD/KG)

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GLOBAL SALES INFORMATION

US Medicaid

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Data Compilation #PharmaFlow

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Chemistry

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Also known as: Baycol, Rivastatin, 143201-11-0, Lipobay, Bay w 6228, Certa
Molecular Formula
C26H33FNNaO5
Molecular Weight
481.5  g/mol
InChI Key
GPUADMRJQVPIAS-QCVDVZFFSA-M
FDA UNII
6Q18G1060S

Cerivastatin
Cerivastatin Sodium is the sodium salt of cerivastatin, a synthetic lipid-lowering agent.
1 2D Structure

Cerivastatin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(E,3R,5S)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate
2.1.2 InChI
InChI=1S/C26H34FNO5.Na/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4;/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32);/q;+1/p-1/b11-10+;/t19-,20-;/m1./s1
2.1.3 InChI Key
GPUADMRJQVPIAS-QCVDVZFFSA-M
2.1.4 Canonical SMILES
CC(C)C1=C(C(=C(C(=N1)C(C)C)COC)C2=CC=C(C=C2)F)C=CC(CC(CC(=O)[O-])O)O.[Na+]
2.1.5 Isomeric SMILES
CC(C)C1=C(C(=C(C(=N1)C(C)C)COC)C2=CC=C(C=C2)F)/C=C/[C@H](C[C@H](CC(=O)[O-])O)O.[Na+]
2.2 Other Identifiers
2.2.1 UNII
6Q18G1060S
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6-heptenoic Acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-, Monosodium Salt, (s-(r*,s*-(e)))-

2. 7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyrid-3-yl)-3,5-dihydroxy-6-heptenoate Sodium Salt

3. Bay W 6228

4. Baycol

5. Cerivastatin

6. Certa

7. Kazak

8. Lipobay

9. Rivastatin

2.3.2 Depositor-Supplied Synonyms

1. Baycol

2. Rivastatin

3. 143201-11-0

4. Lipobay

5. Bay W 6228

6. Certa

7. Cerivastatin Sodium [usan]

8. Cerivastatin, Sodium Salt

9. Bay-w-6228

10. Cerivastatin Na

11. Cerivastatin Sodium Salt

12. Cpd000469148

13. Chebi:3559

14. (+)-sodium (3r,5s,6e)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoate

15. 143201-11-0 (sodium)

16. 6q18g1060s

17. Cerivastatin (sodium)

18. Dsstox_cid_26488

19. Dsstox_rid_81659

20. Dsstox_gsid_46488

21. 6-heptanoic Acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-(s-(r*,s*-(e)))-, Sodium Salt

22. Sodium (3r,5s,e)-7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl)-3,5-dihydroxyhept-6-enoate

23. Cas-143201-11-0

24. Ncgc00164625-02

25. Cerivastatinsodium

26. Unii-6q18g1060s

27. Baycol (tn)

28. 7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyrid-3-yl)-3,5-dihydroxy-6-heptenoate Sodium Salt

29. Bayw6228

30. Schembl41887

31. Schembl41888

32. 6-heptenoic Acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-, Monosodium Salt, (s-(r*,s*-(e)))-

33. Mls001424071

34. Chembl1200563

35. Dtxsid0046488

36. Cerivastatin Sodium (jan/usan)

37. Cerivastatin Sodium [jan]

38. Hms2051h13

39. Cerivastatin Sodium [vandf]

40. Cerivastatin Sodium [mart.]

41. Tox21_112244

42. Tox21_303882

43. Cerivastatin Sodium [who-dd]

44. Cerivastatin Sodium Salt [mi]

45. Akos015967306

46. Akos025149364

47. Tox21_112244_1

48. Ccg-100954

49. Nc00204

50. Cerivastatin Sodium [orange Book]

51. Ncgc00164625-04

52. Ncgc00357289-01

53. (3r,5s,6e)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt

54. 6-heptenoic Acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-, Monosodium Salt, (3r,5s,6e)-

55. Smr000469148

56. Hy-109523

57. Cs-0031250

58. D00889

59. A808034

60. J-007766

61. Q27106131

62. Sodium (3r,5s,6e)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate

63. Sodium (e,3r,5s)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)-3-pyridinyl]-3,5-dihydroxy-6-heptenoate

64. Sodium (e,3r,5s)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-bis(oxidanyl)hept-6-enoate

65. Sodium;(e,3r,5s)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 481.5 g/mol
Molecular Formula C26H33FNNaO5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count11
Exact Mass481.22404560 g/mol
Monoisotopic Mass481.22404560 g/mol
Topological Polar Surface Area103 Ų
Heavy Atom Count34
Formal Charge0
Complexity626
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis. (See all compounds classified as Hydroxymethylglutaryl-CoA Reductase Inhibitors.)


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ABOUT THIS PAGE

Looking for 143201-11-0 / Cerivastatin API manufacturers, exporters & distributors?

Cerivastatin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cerivastatin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cerivastatin manufacturer or Cerivastatin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cerivastatin manufacturer or Cerivastatin supplier.

PharmaCompass also assists you with knowing the Cerivastatin API Price utilized in the formulation of products. Cerivastatin API Price is not always fixed or binding as the Cerivastatin Price is obtained through a variety of data sources. The Cerivastatin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cerivastatin

Synonyms

Baycol, Rivastatin, 143201-11-0, Lipobay, Bay w 6228, Certa

Cas Number

143201-11-0

Unique Ingredient Identifier (UNII)

6Q18G1060S

About Cerivastatin

Cerivastatin Sodium is the sodium salt of cerivastatin, a synthetic lipid-lowering agent.

rivastatin Manufacturers

A rivastatin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of rivastatin, including repackagers and relabelers. The FDA regulates rivastatin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. rivastatin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

rivastatin Suppliers

A rivastatin supplier is an individual or a company that provides rivastatin active pharmaceutical ingredient (API) or rivastatin finished formulations upon request. The rivastatin suppliers may include rivastatin API manufacturers, exporters, distributors and traders.

rivastatin GMP

rivastatin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of rivastatin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right rivastatin GMP manufacturer or rivastatin GMP API supplier for your needs.

rivastatin CoA

A rivastatin CoA (Certificate of Analysis) is a formal document that attests to rivastatin's compliance with rivastatin specifications and serves as a tool for batch-level quality control.

rivastatin CoA mostly includes findings from lab analyses of a specific batch. For each rivastatin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

rivastatin may be tested according to a variety of international standards, such as European Pharmacopoeia (rivastatin EP), rivastatin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (rivastatin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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