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Chemistry

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Also known as:
Molecular Formula
C43H58N4O12
Molecular Weight
822.9  g/mol
InChI Key
FZYOVNIOYYPUPY-ZTWDQPHTSA-N

Rifampicin
1 2D Structure

Rifampicin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z,26E)-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[[(4-methylpiperazin-1-yl)amino]methylidene]-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29)-heptaen-13-yl] acetate
2.1.2 InChI
InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,44,49-51,53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,28-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
2.1.3 InChI Key
FZYOVNIOYYPUPY-ZTWDQPHTSA-N
2.1.4 Canonical SMILES
CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=O)C2=CNN5CCN(CC5)C)O)C
2.1.5 Isomeric SMILES
C[C@H]1/C=C/C=C(\C(=O)NC\2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C(=O)/C2=C/NN5CCN(CC5)C)O)/C
2.2 Synonyms
2.2.1 Other Synonyms

1. Rifomycin S

2. Rifampicin S

2.3 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 822.9 g/mol
Molecular Formula C43H58N4O12
XLogP34
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count15
Rotatable Bond Count5
Exact Mass822.40512330 g/mol
Monoisotopic Mass822.40512330 g/mol
Topological Polar Surface Area217 A^2
Heavy Atom Count59
Formal Charge0
Complexity1750
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count4
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameRifadin
PubMed HealthRifampin (Injection)
Drug ClassesAntitubercular
Drug LabelRIFADIN (rifampin capsules USP) for oral administration contain 150 mg or 300 mg rifampin per capsule. The 150 mg and 300 mg capsules also contain, as inactive ingredients: corn starch, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin
Active IngredientRifampin
Dosage FormCapsule; Injectable
RouteInjection; Oral
Strength150mg; 300mg; 600mg/vial
Market StatusPrescription
CompanySanofi Aventis Us

2 of 6  
Drug NameRifampin
Active IngredientRifampin
Dosage FormCapsule; Injectable
RouteInjection; Oral
Strength150mg; 300mg; 600mg/vial
Market StatusPrescription
CompanyBedford; Lupin Pharms; Sandoz; Emcure Pharms; Fresenius Kabi Usa; Versapharm; Lannett; Agila Speclts

3 of 6  
Drug NameRimactane
PubMed HealthRifampin
Drug ClassesAntitubercular
Drug LabelRifampin is a semisynthetic antibiotic derivative of rifamycin SV. Rifampin is a red-brown crystalline powder very slightly soluble in water at neutral pH, freely soluble in chloroform, soluble in ethyl acetate and in methanol. Its molecular weight i...
Active IngredientRifampin
Dosage FormCapsule
RouteOral
Strength300mg
Market StatusPrescription
CompanyProsam Labs

4 of 6  
Drug NameRifadin
PubMed HealthRifampin (Injection)
Drug ClassesAntitubercular
Drug LabelRIFADIN (rifampin capsules USP) for oral administration contain 150 mg or 300 mg rifampin per capsule. The 150 mg and 300 mg capsules also contain, as inactive ingredients: corn starch, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin
Active IngredientRifampin
Dosage FormCapsule; Injectable
RouteInjection; Oral
Strength150mg; 300mg; 600mg/vial
Market StatusPrescription
CompanySanofi Aventis Us

5 of 6  
Drug NameRifampin
Active IngredientRifampin
Dosage FormCapsule; Injectable
RouteInjection; Oral
Strength150mg; 300mg; 600mg/vial
Market StatusPrescription
CompanyBedford; Lupin Pharms; Sandoz; Emcure Pharms; Fresenius Kabi Usa; Versapharm; Lannett; Agila Speclts

6 of 6  
Drug NameRimactane
PubMed HealthRifampin
Drug ClassesAntitubercular
Drug LabelRifampin is a semisynthetic antibiotic derivative of rifamycin SV. Rifampin is a red-brown crystalline powder very slightly soluble in water at neutral pH, freely soluble in chloroform, soluble in ethyl acetate and in methanol. Its molecular weight i...
Active IngredientRifampin
Dosage FormCapsule
RouteOral
Strength300mg
Market StatusPrescription
CompanyProsam Labs

API SUPPLIERS

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Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1764095400,"product":"RIFAMPICIN IP B.D.0.7 RIFAMPICIN IP B.D.0.7","address":"304,ATLANTA ARCADE,","city":"MUMBAI MAHARASHTRA","supplier":"ZHEJIANG CHEMICALS IMPORT AND EXPORT CORP","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"MACLEODS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"155","totalValueFC":"780397.5","currency":"USD","unitRateINR":"13872.5","date":"26-Nov-2025","totalValueINR":"69362500","totalValueInUsd":"780397.5","indian_port":"JNPT","hs_no":"29419011","bill_no":"18292","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"10F BUILDING 4, TAIPING FINANCE TOW ERNO 199 SHIMIN STREET, SHANGCHENG DISRICT HANGZHOU, CHINA SDNF","customerAddress":"304,ATLANTA ARCADE,"},{"dataSource":"API Import","activeIngredients":"","year":"2026","qtr":"Q1","strtotime":1769538600,"product":"RIFAMPICIN IP IUPAC NAME:[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15-17,27,29-PENTAHYDROXY-11-METHOXY-3,7,12,1RIFAMPICIN IP IUPAC NAME:[(7S,9E,11S,12R,13S,14R,15R,16R,17S","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"HEBEI XINGANG PHARMACEUTICAL COLTD","supplierCountry":"CHINA","foreign_port":"KUNMING","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"176.5","totalValueFC":"354745.7","currency":"USD","unitRateINR":"16094.1","date":"28-Jan-2026","totalValueINR":"32188155.4","totalValueInUsd":"354745.7","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29419011","bill_no":"52","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"KUNMING","supplierAddress":"NO.2, FUQIANG STREET, ZHAOYUAN ROAD , ZHAO COUNTY, SHIJIAZHUANG HEBEI PROVINCE, CHINA 051530 China","customerAddress":"159, C.S.T. ROAD,"}]
27-Jan-2022
28-Jan-2026
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Europe

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SANOFI SpA

France
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Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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Regulatory Info :

Registration Country : Italy

Rifampin

Brand Name : Rifadin

Dosage Form : Rifampicin 2% 60Ml Oral Use

Dosage Strength : 1 bottle 60 ml 20 mg/ml syrup

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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02

SANOFI SpA

France
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Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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Regulatory Info :

Registration Country : Italy

Rifampin

Brand Name : Rifadin

Dosage Form : Rifampicin 450Mg 8 Joined' Oral Use

Dosage Strength : 8 cpr riv 450 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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03

SANOFI SpA

France
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Regulatory Info :

Registration Country : Italy

Rifampin

Brand Name : Rifadin

Dosage Form : Rifampicin 600Mg 1 Unit Parenteral Use

Dosage Strength : 1 ampoule EV 600 mg + 1 ampoule solv 10 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Regulatory Info : Allowed

Registration Country : Switzerland

Rifampicin; Isoniazid

Brand Name : Rifinah

Dosage Form : Coated Tablet

Dosage Strength :

Packaging :

Approval Date : 18/09/1975

Application Number : 38931

Regulatory Info : Allowed

Registration Country : Switzerland

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05

Sanofi S.R.L

France
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Digital Content Digital Content

Regulatory Info : Withdrawn

Registration Country : Malta

Isoniazid; Rifampicin

Brand Name : Rifinah

Dosage Form : Film Coated Tablet

Dosage Strength : 150MG; 300MG

Packaging :

Approval Date : 2007-08-08

Application Number :

Regulatory Info : Withdrawn

Registration Country : Malta

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06

Sanofi S.R.L

France
  • fda
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  • WHO-GMP

Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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Digital Content Digital Content

Regulatory Info : Withdrawn

Registration Country : Malta

Isoniazid; Rifampicin

Brand Name : Rifinah

Dosage Form : Film Coated Tablet

Dosage Strength : 100MG; 150MG

Packaging :

Approval Date : 2011-03-14

Application Number :

Regulatory Info : Withdrawn

Registration Country : Malta

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07

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Regulatory Info : Authorized

Registration Country : Spain

Isoniazide; Pyrazinamide; Rifampicin

Brand Name : Rifater Coated Tablets

Dosage Form : Film Coated Tablet

Dosage Strength :

Packaging :

Approval Date : 01-04-1989

Application Number : 58299

Regulatory Info : Authorized

Registration Country : Spain

Sanofi Company Banner

08

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Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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Digital Content Digital Content

Regulatory Info : Authorized

Registration Country : Spain

Isoniazide; Rifampicin

Brand Name : Rifinah

Dosage Form : Film Coated Tablet

Dosage Strength : 300MG; 150 MG

Packaging :

Approval Date : 01-09-1978

Application Number : 54213

Regulatory Info : Authorized

Registration Country : Spain

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09

  • fda
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  • WHO-GMP

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Regulatory Info : Authorized

Registration Country : Spain

Rifampicin

Brand Name : Rifaldin

Dosage Form : Capsule

Dosage Strength : 300MG

Packaging :

Approval Date : 01-06-1968

Application Number : 46029

Regulatory Info : Authorized

Registration Country : Spain

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10

  • fda
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  • WHO-GMP

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Regulatory Info : Authorized

Registration Country : Spain

Rifampicin

Brand Name : Rifaldin

Dosage Form : Powder And Solvent For Infusion Solution

Dosage Strength : 600MG

Packaging :

Approval Date : 01-03-1986

Application Number : 56487

Regulatory Info : Authorized

Registration Country : Spain

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Fillers, Diluents & Binders

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Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

Grade : Oral

Category : Co-Processed Excipients, Fillers, Diluents & Binders

04

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Virtual BoothBoai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

Grade : Oral (Pharma Grade)

Category : Fillers, Diluents & Binders

Brand Name : KoVidone® K25

Excipient Details : KoVidone® K25 is used as a low viscosity wet binder in solid dosage forms such as capsules and tablets.

Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP

Technical Specs : NA

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Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Grade : Parenteral

Category : Parenteral

Brand Name : Lactose Monohydrate

Excipient Details : Lactose monohydrate is used as a diluent in inhalation and lyophilized preparations.

Pharmacopoeia Ref : ChP/USP/EP/JP

Technical Specs : NA

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Virtual BoothDr. Paul Lohmann® provides premium mineral salts backed by 140+ years of innovation, quality manufacturing, and global expertise.

Grade : Oral

Category : Fillers, Diluents & Binders

09

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Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

Grade : Oral

Category : Co-Processed Excipients, Fillers, Diluents & Binders

Brand Name : Microlose™

Excipient Details : Microlose (Lactose Monohydrate & Microcrystalline Cellulose) is used as a diluent in oral dosage forms such as tablets.

Pharmacopoeia Ref : USP-NF,BP,EP,IP

Technical Specs : Lactose Monohydrate – 40%, Microcrystalline cellulose – 60%

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DATA COMPILATION #PharmaFlow

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US drug shortages reduce 16% YoY in Q1 2025; CNS drugs, antimicrobials face highest scarcities
The pharmaceutical industry in the United States continued to grapple with drug shortages during the first quarter (Q1) of 2025. According to the American Society of Health‑System Pharmacists (ASHP), the total number of active shortages stood at 270 as of March 31, 2025 — only slightly below the 277 reported in September 2024, but down 16.4 percent from an all‑time high of 323 reported in Q1 2024.These numbers imply that while dramatic surges in drug shortages may have subsided, underlying vulnerabilities in manufacturing, supply chains, and raw‑material sourcing continue to frustrate efforts towards a durable resolution.A deeper analysis of these drug scarcities reveals that 41 percent of the 270 active shortages first emerged in 2022 or earlier. This implies that many of the current disruptions have become chronic in nature and are exerting pressure on pharmacy operations. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available)CNS drugs dominate with 49 meds in short supply; antimicrobials face shortage of 39 drugsClass‑specific analysis reveals that central nervous system (CNS) agents remained the most disrupted category, with 49 distinct CNS drugs having faced scarcities during Q1. This group spans anxiolytics (anti-anxiety drugs) such as clonazepam and flurazepam, sedatives like lorazepam and midazolam, and stimulants such as methylphenidate and lisdexamfetamine. These shortages pose two challenges — controlling seizures and managing sedation in acute care settings. After CNS agents, antimicrobials was the second‑largest category, with shortages affecting 39 drugs. Key antibacterial and anti-fungal agents such as cefotaxime sodium powder for injection, clindamycin phosphate, rifampin, and metronidazole find themselves on ASHP’s active‑shortage roster, threatening both routine hospital protocols and emergency sepsis management.Fluids and electrolytes occupied the third spot, with 29 items facing shortage in Q1 2025. Hormone agents, including insulin analogs, ranked fourth with 24 drugs in short supply.Chemotherapy medications rounded out the top five categories, with 23 antineoplastic agents (a broad class of medications used to treat cancer) flagged as actively constrained in Q1 2025. Notable shortages included azacitidine, carboplatin, methotrexate, and streptozocin. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available) US faces 26 new shortages; Pharmacopeia list warns of 100 vulnerable medicationsThe first quarter saw the emergence of 26 new shortage declarations, emphasizing that even drugs previously deemed reliably sourced can fall into scarcity. The US has been facing a shortage of attention deficit hyperactivity disorder (ADHD) drugs since 2022. The new shortages included ADHD transdermal patch methylphenidate, peginterferon alfa‑2a (Pegasys) used in chronic hepatitis B and C, and bacitracin ophthalmic ointment.The fragility of the pharmaceutical supply chains has been particularly evident in the aftermath of natural disasters. Hurricane Helene’s flooding at Baxter’s Marion, North Carolina, facility deeply affected IV‑solution supply lines. Baxter supplies roughly 60 percent of the US’ IV fluids and the ASHP report listed “hurricane” as the reason behind nine percent of drug shortages, as of January 2025.Regulatory and policy interventions continue to evolve. The US Pharmacopeia’s inaugural Vulnerable Medicines List, launched in 2025, identifies 100 drugs at the highest risk of future shortages, with a particular focus on injectables (comprising 71 percent of the list) and essential hospital care.Antibiotics, medications for pain management and oncology are the other drugs on the list. Although 61 percent of these vulnerable medicines were not in active shortage at the time of listing, their inclusion is intended to galvanize manufacturers and purchasing organizations to bolster inventories.Meanwhile, the Government Accountability Office in the US has called on the Department of Health and Human Services (HHS) to establish a formal coordination mechanism, warning that elimination of the HHS supply‑chain coordinator role in May 2025 risks fragmenting federal response efforts. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available) Global shortages mirror US patterns; Europe launches monitoring platform Globally, we notice comparable trends. For instance, Europe has rolled out the European Shortages Monitoring Platform (ESMP) this year in order to centralize shortage reporting across member states. Critical‑medicine shortages in the EU — in areas such as oncology, ADHD, and critical care analgesics — mirror US patterns. The European Medicines Agency’s shortage list currently holds 37 human drugs.According to Health Canada’s May 12, 2025 update, its Tier 3 list had 18 drug shortages that are considered to have the greatest impact on Canada’s drug supply and health‑care system. Tier 3 designation is based on medical necessity and minimal availability of alternatives.In hematology and oncology, scarcity of essential drugs like Oncaspar for acute lymphoblastic leukemia, idarubicin and lomustine for leukemias and brain tumors, anagrelide for thrombocythemia, and preservative‑free methotrexate for various malignancies underscore the impact these drug shortages can have on treatment. View Our Interactive Dashboard on Drug Shortages So Far in 2025 (Free Excel Available) Our viewThe global pharma supply chain is dealing with a fresh wave of uncertainties, especially with the likelihood of tariffs on drugs imported into the US. Analysts warn that the proposed pharmaceutical tariffs could exacerbate supply issues.Over 50 percent of drugs used in the US are manufactured abroad. Generic sterile injectable drugs — like chemotherapy medications and IV saline — are particularly vulnerable due to their complex manufacturing processes and low profit margins. Generic drugs (which account for 90 percent of prescriptions filled in the US) could face increased pressure, as many rely on raw materials from China and India. This could result in more severe drug shortages in the future. 

Impressions: 4746

https://www.pharmacompass.com/radio-compass-blog/us-drug-shortages-reduce-16-yoy-in-q1-2025-cns-drugs-antimicrobials-face-highest-scarcities

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22 May 2025

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Brand Name : Rifater

France
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RX/OTC/DISCN : Class A

Isoniazid; Pyrazinamide; Rifampicin

Dosage Form : Isoniazid+Pyrazinamide+Rifampici...

Dosage Strength : 40 cpr riv 50 mg + 300mg + 120 mg

Price Per Pack (Euro) : 10.57

Published in :

Country : Italy

RX/OTC/DISCN : Class A

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02

Brand Name : Rifadin

France
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RX/OTC/DISCN : Class A

Rifampicin

Dosage Form : Rifampicin 2% 60Ml Oral Use

Dosage Strength : 1 bottle 60 ml 20 mg/ml syrup

Price Per Pack (Euro) : 2.8

Published in :

Country : Italy

RX/OTC/DISCN : Class A

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Brand Name : Rifadin

France
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RX/OTC/DISCN : Class A

Rifampicin

Dosage Form : Rifampicin 300Mg 8 Joined' Oral ...

Dosage Strength : 8 cps 300 mg

Price Per Pack (Euro) : 3.72

Published in :

Country : Italy

RX/OTC/DISCN : Class A

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Brand Name : Rifadin

France
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RX/OTC/DISCN : Class A

Rifampicin

Dosage Form : Rifampicin 450Mg 8 Joined' Oral ...

Dosage Strength : 8 cpr riv 450 mg

Price Per Pack (Euro) : 4.86

Published in :

Country : Italy

RX/OTC/DISCN : Class A

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Brand Name : Rifadin

France
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RX/OTC/DISCN : Class A

Rifampicin

Dosage Form : Rifampicin 600Mg 1 Unit Parenter...

Dosage Strength : 1 ampoule EV 600 mg + 1 ampoule solv 10 ml

Price Per Pack (Euro) : 9.28

Published in :

Country : Italy

RX/OTC/DISCN : Class A

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Brand Name : Rifinah

France
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RX/OTC/DISCN : Class A

Rifampicin; Isoniazid

Dosage Form : Rifampicin+Isoniazid+150300 Mg 2...

Dosage Strength : 24 cpr riv 300 mg + 150 mg

Price Per Pack (Euro) : 9.48

Published in :

Country : Italy

RX/OTC/DISCN : Class A

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07

Brand Name : RIFAMPIN

U.S.A
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Not Confirmed

Brand Name : RIFAMPIN

U.S.A
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Rifampicin

Dosage Form : CAPSULE;ORAL

Dosage Strength : 150MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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08

Brand Name : RIFAMPIN

U.S.A
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Not Confirmed

Brand Name : RIFAMPIN

U.S.A
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Not Confirmed

Rifampicin

Dosage Form : CAPSULE;ORAL

Dosage Strength : 300MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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09

Brand Name : RIFAMPIN

U.S.A
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Not Confirmed

Brand Name : RIFAMPIN

U.S.A
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Not Confirmed

Rifampicin

Dosage Form : CAPSULE;ORAL

Dosage Strength : 300MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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10

Brand Name : RIFAMPIN

U.S.A
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Not Confirmed

Brand Name : RIFAMPIN

U.S.A
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Rifampicin

Dosage Form : CAPSULE;ORAL

Dosage Strength : 150MG

Price Per Pack :

Published in :

Country : USA

RX/OTC/DISCN : RX

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Rifampicin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Rifampicin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Rifampicin manufacturer or Rifampicin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Rifampicin manufacturer or Rifampicin supplier.

PharmaCompass also assists you with knowing the Rifampicin API Price utilized in the formulation of products. Rifampicin API Price is not always fixed or binding as the Rifampicin Price is obtained through a variety of data sources. The Rifampicin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Rifampicin

Riforal Manufacturers

A Riforal manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Riforal, including repackagers and relabelers. The FDA regulates Riforal manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Riforal API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Riforal manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Riforal Suppliers

A Riforal supplier is an individual or a company that provides Riforal active pharmaceutical ingredient (API) or Riforal finished formulations upon request. The Riforal suppliers may include Riforal API manufacturers, exporters, distributors and traders.

click here to find a list of Riforal suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Riforal USDMF

A Riforal DMF (Drug Master File) is a document detailing the whole manufacturing process of Riforal active pharmaceutical ingredient (API) in detail. Different forms of Riforal DMFs exist exist since differing nations have different regulations, such as Riforal USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Riforal DMF submitted to regulatory agencies in the US is known as a USDMF. Riforal USDMF includes data on Riforal's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Riforal USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Riforal suppliers with USDMF on PharmaCompass.

Riforal JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Riforal Drug Master File in Japan (Riforal JDMF) empowers Riforal API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Riforal JDMF during the approval evaluation for pharmaceutical products. At the time of Riforal JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Riforal suppliers with JDMF on PharmaCompass.

Riforal KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Riforal Drug Master File in Korea (Riforal KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Riforal. The MFDS reviews the Riforal KDMF as part of the drug registration process and uses the information provided in the Riforal KDMF to evaluate the safety and efficacy of the drug.

After submitting a Riforal KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Riforal API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Riforal suppliers with KDMF on PharmaCompass.

Riforal CEP

A Riforal CEP of the European Pharmacopoeia monograph is often referred to as a Riforal Certificate of Suitability (COS). The purpose of a Riforal CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Riforal EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Riforal to their clients by showing that a Riforal CEP has been issued for it. The manufacturer submits a Riforal CEP (COS) as part of the market authorization procedure, and it takes on the role of a Riforal CEP holder for the record. Additionally, the data presented in the Riforal CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Riforal DMF.

A Riforal CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Riforal CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Riforal suppliers with CEP (COS) on PharmaCompass.

Riforal WC

A Riforal written confirmation (Riforal WC) is an official document issued by a regulatory agency to a Riforal manufacturer, verifying that the manufacturing facility of a Riforal active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Riforal APIs or Riforal finished pharmaceutical products to another nation, regulatory agencies frequently require a Riforal WC (written confirmation) as part of the regulatory process.

click here to find a list of Riforal suppliers with Written Confirmation (WC) on PharmaCompass.

Riforal NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Riforal as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Riforal API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Riforal as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Riforal and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Riforal NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Riforal suppliers with NDC on PharmaCompass.

Riforal GMP

Riforal Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Riforal GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Riforal GMP manufacturer or Riforal GMP API supplier for your needs.

Riforal CoA

A Riforal CoA (Certificate of Analysis) is a formal document that attests to Riforal's compliance with Riforal specifications and serves as a tool for batch-level quality control.

Riforal CoA mostly includes findings from lab analyses of a specific batch. For each Riforal CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Riforal may be tested according to a variety of international standards, such as European Pharmacopoeia (Riforal EP), Riforal JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Riforal USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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