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Also known as: 130-40-5, Riboflavin 5'-phosphate sodium, Riboflavin-5'-phosphate sodium, Photrexa, Riboflavin phosphate sodium, Fmn-na
Molecular Formula
C17H20N4NaO9P
Molecular Weight
478.3  g/mol
InChI Key
OHSHFZJLPYLRIP-BMZHGHOISA-M
FDA UNII
957E53WV42

Riboflavin 5 Phosphate Sodium
A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
1 2D Structure

Riboflavin 5 Phosphate Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
2.1.2 InChI
InChI=1S/C17H21N4O9P.Na/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);/q;+1/p-1/t11-,12+,14-;/m0./s1
2.1.3 InChI Key
OHSHFZJLPYLRIP-BMZHGHOISA-M
2.1.4 Canonical SMILES
CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)[O-])O)O)O.[Na+]
2.1.5 Isomeric SMILES
CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)[O-])O)O)O.[Na+]
2.2 Other Identifiers
2.2.1 UNII
957E53WV42
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5'-monophosphate, Riboflavin

2. 5'-phosphate, Riboflavin

3. Flavin Mononucleotide

4. Flavin Mononucleotide Disodium Salt

5. Flavin Mononucleotide Monosodium Salt

6. Flavin Mononucleotide Monosodium Salt, Dihydrate

7. Flavin Mononucleotide Sodium Salt

8. Fmn

9. Mononucleotide, Flavin

10. Mononucleotide, Riboflavin

11. Phosphate, Sodium Riboflavin

12. Riboflavin 5' Monophosphate

13. Riboflavin 5' Phosphate

14. Riboflavin 5'-monophosphate

15. Riboflavin 5'-phosphate

16. Riboflavin Mononucleotide

17. Riboflavin Phosphate, Sodium

18. Sodium Riboflavin Phosphate

2.3.2 Depositor-Supplied Synonyms

1. 130-40-5

2. Riboflavin 5'-phosphate Sodium

3. Riboflavin-5'-phosphate Sodium

4. Photrexa

5. Riboflavin Phosphate Sodium

6. Fmn-na

7. Flavin Mononucleotide

8. Riboflavin 5-phosphate Sodium

9. Riboflavin (phosphate Sodium)

10. Vitamin B2 Phosphate Sodium Salt

11. Riboflavin 5'-monophosphate Sodium Salt

12. Riboflavin 5'-phosphate Sodium Anhydrous

13. Sodium Riboflavin 5'-phosphate

14. Lactoflavin Phosphate Sodium Salt

15. 957e53wv42

16. Riboflavin 5'-(dihydrogen Phosphate), Sodium Salt (1:1)

17. Photrexa Viscous In Dextran 20%

18. Riboflavin Sodium Phosphate [jan]

19. Riboflavin 5'-(dihydrogen Phosphate), Monosodium Salt

20. Sodium Riboflavin Phosphate

21. Riboflavina 5 Fosfato De Sodio

22. Unii-957e53wv42

23. Infuvite (tn)

24. Einecs 204-988-6

25. Einecs 244-868-0

26. Photrexa Viscous

27. Riboflavin 5'-(sodium Hydrogen Phosphate)

28. Nsc-759230

29. Schembl26122

30. Riboflavin 5'-(dihydrogen Phosphate), Sodium Salt

31. Ins No.101(ii)

32. Riboflavine-5'-phosphate Sodium

33. Chebi:32098

34. Ins-101(ii)

35. Riboflavin Sodium Phosphate,(s)

36. Dtxsid80889330

37. Flavin Mononucleotide Sodium Salt

38. Hy-b0964

39. Riboflavin Sodium Phosphate (jp17)

40. E-101(ii)

41. Flavin Mononucleotide Monosodium Salt

42. Mfcd00065362

43. Ccg-269524

44. Cs-4449

45. Nsc 759230

46. Riboflavin Monophosphate Monosodium Salt

47. 22251-85-0

48. E106

49. Sodium Riboflavin Phosphate [inci]

50. Riboflavin Sodium Phosphate [mart.]

51. Riboflavin Sodium Phosphate Anhydrous

52. R0023

53. R0249

54. Riboflavin Sodium Phosphate [who-dd]

55. D01622

56. A806082

57. Flavin Mononucleotide Monosodium Salt [mi]

58. Riboflavin Sodium Phosphate [ep Monograph]

59. W-108348

60. Q27271760

61. Sodium (2r,3s,4s)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2h)-yl)-2,3,4-trihydroxypentyl Hydrogen Phosphate

62. Sodium (2r,3s,4s)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2h)-yl)-2,3,4-trihydroxypentyl Hydrogenphosphate

63. Sodium [5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)-2,3,4-trihydroxy-pentyl] Hydrogen Phosphate Dihydrate;riboflavin Phosphate Sodium

64. Sodium;[(2r,3s,4s)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] Hydrogen Phosphate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 478.3 g/mol
Molecular Formula C17H20N4NaO9P
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass478.08655951 g/mol
Monoisotopic Mass478.08655951 g/mol
Topological Polar Surface Area204 Ų
Heavy Atom Count32
Formal Charge0
Complexity856
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vitamin B Complex

A group of water-soluble vitamins, some of which are COENZYMES. (See all compounds classified as Vitamin B Complex.)


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11-Jan-2022
27-Jun-2025
KGS
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DOSAGE - FOR SOLUTION;INTRAVENOUS - 80MG/VIAL...DOSAGE - FOR SOLUTION;INTRAVENOUS - 80MG/VIAL;0.02MG/VIAL;0.001MG/VIAL;5MG/VIAL;0.01MG/VIAL;0.14MG/VIAL;17MG/VIAL;0.2MG/VIAL;1MG/VIAL;1.4MG/VIAL;EQ 1.2MG BASE/VIAL;0.7MG/VIAL;7MG/VIAL

USFDA APPLICATION NUMBER - 18920

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DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;0.03MG/ML

USFDA APPLICATION NUMBER - 21163

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DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;30MCG/ML

USFDA APPLICATION NUMBER - 21163

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DOSAGE - INJECTABLE;INTRAVENOUS - 200MG/VIAL;...DOSAGE - INJECTABLE;INTRAVENOUS - 200MG/VIAL;0.06MG/VIAL;0.005MG/VIAL;15MG/VIAL;0.005MG/VIAL;0.6MG/VIAL;40MG/VIAL;6MG/VIAL;3.6MG/VIAL;6MG/VIAL;1MG/VIAL;10MG/VIAL;0.15MG/VIAL

USFDA APPLICATION NUMBER - 21625

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DOSAGE - INJECTABLE;INJECTION - 20MG/ML;0.006...DOSAGE - INJECTABLE;INJECTION - 20MG/ML;0.006MG/ML;0.05MCG/ML;1.5MG/ML;0.0005MG/ML;0.06MG/ML;4MG/ML;0.6MG/ML;0.36MG/ML;0.6MG/ML;0.1MG/ML;1MG/ML

USFDA APPLICATION NUMBER - 8809

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Looking for 130-40-5 / Riboflavin 5 Phosphate Sodium API manufacturers, exporters & distributors?

Riboflavin 5 Phosphate Sodium manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Riboflavin 5 Phosphate Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Riboflavin 5 Phosphate Sodium manufacturer or Riboflavin 5 Phosphate Sodium supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Riboflavin 5 Phosphate Sodium manufacturer or Riboflavin 5 Phosphate Sodium supplier.

PharmaCompass also assists you with knowing the Riboflavin 5 Phosphate Sodium API Price utilized in the formulation of products. Riboflavin 5 Phosphate Sodium API Price is not always fixed or binding as the Riboflavin 5 Phosphate Sodium Price is obtained through a variety of data sources. The Riboflavin 5 Phosphate Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Riboflavin 5 Phosphate Sodium

Synonyms

130-40-5, Riboflavin 5'-phosphate sodium, Riboflavin-5'-phosphate sodium, Photrexa, Riboflavin phosphate sodium, Fmn-na

Cas Number

130-40-5

Unique Ingredient Identifier (UNII)

957E53WV42

About Riboflavin 5 Phosphate Sodium

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.

Riboflavin 5'-phosphate sodium Manufacturers

A Riboflavin 5'-phosphate sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Riboflavin 5'-phosphate sodium, including repackagers and relabelers. The FDA regulates Riboflavin 5'-phosphate sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Riboflavin 5'-phosphate sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Riboflavin 5'-phosphate sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Riboflavin 5'-phosphate sodium Suppliers

A Riboflavin 5'-phosphate sodium supplier is an individual or a company that provides Riboflavin 5'-phosphate sodium active pharmaceutical ingredient (API) or Riboflavin 5'-phosphate sodium finished formulations upon request. The Riboflavin 5'-phosphate sodium suppliers may include Riboflavin 5'-phosphate sodium API manufacturers, exporters, distributors and traders.

click here to find a list of Riboflavin 5'-phosphate sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Riboflavin 5'-phosphate sodium USDMF

A Riboflavin 5'-phosphate sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Riboflavin 5'-phosphate sodium active pharmaceutical ingredient (API) in detail. Different forms of Riboflavin 5'-phosphate sodium DMFs exist exist since differing nations have different regulations, such as Riboflavin 5'-phosphate sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Riboflavin 5'-phosphate sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Riboflavin 5'-phosphate sodium USDMF includes data on Riboflavin 5'-phosphate sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Riboflavin 5'-phosphate sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Riboflavin 5'-phosphate sodium suppliers with USDMF on PharmaCompass.

Riboflavin 5'-phosphate sodium JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Riboflavin 5'-phosphate sodium Drug Master File in Japan (Riboflavin 5'-phosphate sodium JDMF) empowers Riboflavin 5'-phosphate sodium API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Riboflavin 5'-phosphate sodium JDMF during the approval evaluation for pharmaceutical products. At the time of Riboflavin 5'-phosphate sodium JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Riboflavin 5'-phosphate sodium suppliers with JDMF on PharmaCompass.

Riboflavin 5'-phosphate sodium CEP

A Riboflavin 5'-phosphate sodium CEP of the European Pharmacopoeia monograph is often referred to as a Riboflavin 5'-phosphate sodium Certificate of Suitability (COS). The purpose of a Riboflavin 5'-phosphate sodium CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Riboflavin 5'-phosphate sodium EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Riboflavin 5'-phosphate sodium to their clients by showing that a Riboflavin 5'-phosphate sodium CEP has been issued for it. The manufacturer submits a Riboflavin 5'-phosphate sodium CEP (COS) as part of the market authorization procedure, and it takes on the role of a Riboflavin 5'-phosphate sodium CEP holder for the record. Additionally, the data presented in the Riboflavin 5'-phosphate sodium CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Riboflavin 5'-phosphate sodium DMF.

A Riboflavin 5'-phosphate sodium CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Riboflavin 5'-phosphate sodium CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Riboflavin 5'-phosphate sodium suppliers with CEP (COS) on PharmaCompass.

Riboflavin 5'-phosphate sodium WC

A Riboflavin 5'-phosphate sodium written confirmation (Riboflavin 5'-phosphate sodium WC) is an official document issued by a regulatory agency to a Riboflavin 5'-phosphate sodium manufacturer, verifying that the manufacturing facility of a Riboflavin 5'-phosphate sodium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Riboflavin 5'-phosphate sodium APIs or Riboflavin 5'-phosphate sodium finished pharmaceutical products to another nation, regulatory agencies frequently require a Riboflavin 5'-phosphate sodium WC (written confirmation) as part of the regulatory process.

click here to find a list of Riboflavin 5'-phosphate sodium suppliers with Written Confirmation (WC) on PharmaCompass.

Riboflavin 5'-phosphate sodium NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Riboflavin 5'-phosphate sodium as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Riboflavin 5'-phosphate sodium API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Riboflavin 5'-phosphate sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Riboflavin 5'-phosphate sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Riboflavin 5'-phosphate sodium NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Riboflavin 5'-phosphate sodium suppliers with NDC on PharmaCompass.

Riboflavin 5'-phosphate sodium GMP

Riboflavin 5'-phosphate sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Riboflavin 5'-phosphate sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Riboflavin 5'-phosphate sodium GMP manufacturer or Riboflavin 5'-phosphate sodium GMP API supplier for your needs.

Riboflavin 5'-phosphate sodium CoA

A Riboflavin 5'-phosphate sodium CoA (Certificate of Analysis) is a formal document that attests to Riboflavin 5'-phosphate sodium's compliance with Riboflavin 5'-phosphate sodium specifications and serves as a tool for batch-level quality control.

Riboflavin 5'-phosphate sodium CoA mostly includes findings from lab analyses of a specific batch. For each Riboflavin 5'-phosphate sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Riboflavin 5'-phosphate sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Riboflavin 5'-phosphate sodium EP), Riboflavin 5'-phosphate sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Riboflavin 5'-phosphate sodium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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