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Chemistry

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Also known as: Retinyl palmitate, 79-81-2, Retinol palmitate, Retinol, hexadecanoate, All-trans-retinyl palmitate, Arovit
Molecular Formula
C36H60O2
Molecular Weight
524.9  g/mol
InChI Key
VYGQUTWHTHXGQB-FFHKNEKCSA-N
FDA UNII
1D1K0N0VVC

Vitamin A Palmitate
Retinyl Palmitate is a naturally-occurring phenyl analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. As the most common form of vitamin A taken for dietary supplementation, retinyl palmitate binds to and activates retinoid receptors, thereby inducing cell differentiation and decreasing cell proliferation. This agent also inhibits carcinogen-induced neoplastic transformation, induces apoptosis in some cancer cell types, and exhibits immunomodulatory properties. (NCI04)
1 2D Structure

Vitamin A Palmitate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] hexadecanoate
2.1.2 InChI
InChI=1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+
2.1.3 InChI Key
VYGQUTWHTHXGQB-FFHKNEKCSA-N
2.1.4 Canonical SMILES
CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(CCCC1(C)C)C
2.1.5 Isomeric SMILES
CCCCCCCCCCCCCCCC(=O)OC/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(CCCC1(C)C)C
2.2 Other Identifiers
2.2.1 UNII
1D1K0N0VVC
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Chocola A

2. Retinol Palmitate

3. Retinyl Palmitate

2.3.2 Depositor-Supplied Synonyms

1. Retinyl Palmitate

2. 79-81-2

3. Retinol Palmitate

4. Retinol, Hexadecanoate

5. All-trans-retinyl Palmitate

6. Arovit

7. Optovit-a

8. Retinyl Hexadecanoate

9. Aquapalm

10. Dispatabs Tabs

11. Vitazyme A

12. Optovit A

13. Axerophthol Palmitate

14. Trans-retinol Palmitate

15. Trans-retinyl Palmitate

16. [(2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] Hexadecanoate

17. Lutavit A 500 Plus

18. All-trans-retinol Palmitate

19. Arovit (roche)

20. All-trans-vitamin A Palmitate

21. Aquasol A (tn)

22. Retinyl (vitamin A) Palmitate

23. Retinol Palmitate [jan]

24. O~15~-hexadecanoylretinol

25. Nsc-758478

26. 1d1k0n0vvc

27. Retinol, Palmitate, All-trans

28. Ester Found In Fish Liver Oils

29. Retinol Palmitate (6ci,7ci)

30. Chebi:17616

31. Palmitic Acid, Ester With Retinol

32. Retinol, Palmitate, All-trans- (8ci)

33. Ncgc00095056-03

34. Dsstox_cid_1241

35. Dsstox_rid_76033

36. Dsstox_gsid_21241

37. (2e,4e,6e,8e)-hexadecanoic Acid 3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2, 4,6,8,tetraenyl Ester

38. Vitamin A Solubilized

39. Cas-79-81-2

40. (2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl Hexadecanoate

41. Smr000112463

42. Ccris 3280

43. Retinol, Palmitate, All-trans-

44. Einecs 201-228-5

45. Unii-1d1k0n0vvc

46. Brn 1917366

47. Retinylpalmitate

48. Retinol-palmitate

49. Retinyl-palmitate

50. Retinol, All-trans-, Palmitate

51. Palmitic Acid Retinol

52. Retinyl Palmitic Acid

53. Vitamin- A Palmitate

54. Retinyl Hexadecanoic Acid

55. Spectrum5_001201

56. All-(e)-retinol Palmitate

57. Bmse000501

58. Ec 201-228-5

59. Retinol Palmitate (jp17)

60. Chembl1675

61. Schembl41649

62. Mls001332437

63. Mls001332438

64. Spectrum1503604

65. All-trans-retinyl Hexadecanoate

66. Dtxsid1021241

67. Retinyl Palmitate [inci]

68. Hms500m11

69. Retinyl Palmitate [vandf]

70. Vitamin A Palmitate [mi]

71. Hms1922e10

72. Hms2093g13

73. Hms2268c06

74. Pharmakon1600-01503604

75. Retinol Palmitate [who-dd]

76. Retinyl Palmitate [usp-rs]

77. (2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl Palmitate

78. Amy13840

79. Hy-b1384

80. Vae 16:0

81. Vitamin A Palmitate [vandf]

82. Zinc8214494

83. Tox21_113452

84. Tox21_303008

85. Ccg-39342

86. Lmpr01090013

87. Mfcd00019414

88. Nsc758478

89. S4126

90. Retinol, O~15~-(1-oxohexadecyl)-

91. Akos015918435

92. Nsc 758478

93. Vitamin A Palmitate, 1.7 M.i.u./g

94. Idi1_000249

95. Ncgc00095056-01

96. Ncgc00095056-02

97. Ncgc00256427-01

98. Ac-20001

99. Vitamin A Palmitate [orange Book]

100. Sbi-0051830.p002

101. All-(e)-retinol Palmitate [who-ip]

102. Cs-0013116

103. C02588

104. C76552

105. D00164

106. Ab00052360_04

107. A839762

108. Sr-05000001910

109. Vitamin A Palmitate (solubilized) [vandf]

110. Q7316807

111. Sr-05000001910-1

112. Retinyl Palmitate (vitamin A Palmitate; Retinol Palmitate)

113. Retinyl Palmitate, Potency: >=1,700,000 Usp Units Per G

114. Vitamin A (as Palmitate & Beta Carotene) [vandf]

115. Retinyl Palmitate, Type Iv, ~1,800,000 Usp Units/g, Oil

116. Retinyl Palmitate, United States Pharmacopeia (usp) Reference Standard

117. [3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] Hexadecanoate

118. 3,7-dimethyl-9-(2,6,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol Palmitate

119. (2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-en-1-yl)-2,4,6,8-nonateetraen-1-yl-palmitate

120. (2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenyl Palmitate

121. 110067-62-4

122. Hexadecanoic Acid [(2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenyl] Ester

123. Retinyl Palmitate (vitamin A Palmitate), Pharmaceutical Secondary Standard; Certified Reference Material

124. Retinyl Palmitate Solution, 100 Mug/ml (ethanol With 0.1% (w/v) Bht), Ampule Of 1 Ml, Certified Reference Material

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 524.9 g/mol
Molecular Formula C36H60O2
XLogP313.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count21
Exact Mass524.45933115 g/mol
Monoisotopic Mass524.45933115 g/mol
Topological Polar Surface Area26.3 Ų
Heavy Atom Count38
Formal Charge0
Complexity803
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count4
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anticarcinogenic Agents

Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved. (See all compounds classified as Anticarcinogenic Agents.)


Antioxidants

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)


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Riken A Palmitate 1700

Registration Number : 229MF10223

Registrant's Address : 2-9-18 Misakicho, Chiyoda-ku, Tokyo

Initial Date of Registration : 2017-12-25

Latest Date of Registration : 2017-12-25

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Japanese Pharmacopoeia Retinol Palmitate

Registration Number : 217MF10450

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Initial Date of Registration : 2005-08-24

Latest Date of Registration : 2009-08-07

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Japanese Pharmacopoeia Retinol Palmitate

Registration Number : 222MF10268

Registrant's Address : 2-9-18 Misakicho, Chiyoda-ku, Tokyo

Initial Date of Registration : 2010-12-10

Latest Date of Registration : 2010-12-10

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Retinol palmitate Vitamin A Palmitate 1.7 m. I. U. /g (with BHA/BHT)

Registration Number : 218MF10103

Registrant's Address : Wurmisweg 576, CH-4303, Kaiseraugst, Switzerland

Initial Date of Registration : 2006-01-30

Latest Date of Registration : 2006-06-09

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Japanese Pharmacopoeia Retinol Palmitate (with BHA/BHT)

Registration Number : 219MF10114

Registrant's Address : Wurmisweg 576, CH-4303, Kaiseraugst, Switzerland

Initial Date of Registration : 2007-03-23

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API Reference Price

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PALMITATE 1.7 MIU\/G (TOCO)- BATCH NO: UT25021375 -MAKE: DSM 041857929429362100","address":"404 A,GLOBAL CHAMBERS,OFF LINK ROAD","city":"ANDHERI (W) MUMBAI,MAHARASHTRA","supplier":"DSM NUTRITIONAL PRODUCTS ASIA PACIFIC","supplierCountry":"SWITZERLAND","foreign_port":"SINGAPORE","customer":"HEXAGON NUTRITION LTD","customerCountry":"INDIA","quantity":"550.00","actualQuantity":"550","unit":"KGS","unitRateFc":"58.6","totalValueFC":"32271.8","currency":"USD","unitRateINR":"5050","date":"05-Jul-2025","totalValueINR":"2777500","totalValueInUsd":"32271.8","indian_port":"Madras Sea","hs_no":"29362100","bill_no":"3082155","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"SINGAPORE","supplierAddress":"30 PASIR PANJANG ROAD #13-31 MAPLETREE BUSINESS CITY SINGAPORE 117440 SG","customerAddress":"404 A,GLOBAL CHAMBERS,OFF LINK ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1751653800,"product":"VITAMIN A PALMITATE 1.7 MIU\/G (TOCO)- BATCH NO: UT25021377 -MAKE: DSM 041857929429362100","address":"404 A,GLOBAL CHAMBERS,OFF LINK ROAD","city":"ANDHERI (W) MUMBAI,MAHARASHTRA","supplier":"DSM NUTRITIONAL PRODUCTS ASIA PACIFIC","supplierCountry":"SWITZERLAND","foreign_port":"SINGAPORE","customer":"HEXAGON NUTRITION LTD","customerCountry":"INDIA","quantity":"555.00","actualQuantity":"555","unit":"KGS","unitRateFc":"58.6","totalValueFC":"32565.2","currency":"USD","unitRateINR":"5050","date":"05-Jul-2025","totalValueINR":"2802750","totalValueInUsd":"32565.2","indian_port":"Madras Sea","hs_no":"29362100","bill_no":"3082155","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"SINGAPORE","supplierAddress":"30 PASIR PANJANG ROAD #13-31 MAPLETREE BUSINESS CITY SINGAPORE 117440 SG","customerAddress":"404 A,GLOBAL 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KONG","customerAddress":"MUMBAI CENTRAL,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1752085800,"product":"DRY VITAMIN A PALMITATE 250 FOOD GRADE DRY VITAMIN A PALMITATE 250 FOOD GRADE","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"BASF HONG KONG LTD","supplierCountry":"DENMARK","foreign_port":"K?BENHAVN","customer":"CIPLA LTD","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"71.9","totalValueFC":"21611.3","currency":"USD","unitRateINR":"6200","date":"10-Jul-2025","totalValueINR":"1860000","totalValueInUsd":"21611.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29362100","bill_no":"3172701","productDescription":"API","marketType":"REGULATED MARKET","country":"DENMARK","selfForZScoreResived":"Pharma Grade","supplierPort":"K?BENHAVN","supplierAddress":"36\/F, TWO TAIKOO PLACE, TAIKOO PLACE 979 KINGS ROAD QUARRY BAY, HONG KONG HONG KONG","customerAddress":"MUMBAI CENTRAL,"}]
11-Feb-2022
31-Jul-2025
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DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;0.03MG/ML

USFDA APPLICATION NUMBER - 21163

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DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;30MCG/ML

USFDA APPLICATION NUMBER - 21163

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DOSAGE - INJECTABLE;INJECTION - EQ 50,000 UNI...DOSAGE - INJECTABLE;INJECTION - EQ 50,000 UNITS BASE/ML

USFDA APPLICATION NUMBER - 6823

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ABOUT THIS PAGE

Looking for 79-81-2 / Vitamin A Palmitate API manufacturers, exporters & distributors?

Vitamin A Palmitate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Vitamin A Palmitate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Vitamin A Palmitate manufacturer or Vitamin A Palmitate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Vitamin A Palmitate manufacturer or Vitamin A Palmitate supplier.

PharmaCompass also assists you with knowing the Vitamin A Palmitate API Price utilized in the formulation of products. Vitamin A Palmitate API Price is not always fixed or binding as the Vitamin A Palmitate Price is obtained through a variety of data sources. The Vitamin A Palmitate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Vitamin A Palmitate

Synonyms

Retinyl palmitate, 79-81-2, Retinol palmitate, Retinol, hexadecanoate, All-trans-retinyl palmitate, Arovit

Cas Number

79-81-2

Unique Ingredient Identifier (UNII)

1D1K0N0VVC

About Vitamin A Palmitate

Retinyl Palmitate is a naturally-occurring phenyl analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. As the most common form of vitamin A taken for dietary supplementation, retinyl palmitate binds to and activates retinoid receptors, thereby inducing cell differentiation and decreasing cell proliferation. This agent also inhibits carcinogen-induced neoplastic transformation, induces apoptosis in some cancer cell types, and exhibits immunomodulatory properties. (NCI04)

retinol-palmitate Manufacturers

A retinol-palmitate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of retinol-palmitate, including repackagers and relabelers. The FDA regulates retinol-palmitate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. retinol-palmitate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of retinol-palmitate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

retinol-palmitate Suppliers

A retinol-palmitate supplier is an individual or a company that provides retinol-palmitate active pharmaceutical ingredient (API) or retinol-palmitate finished formulations upon request. The retinol-palmitate suppliers may include retinol-palmitate API manufacturers, exporters, distributors and traders.

click here to find a list of retinol-palmitate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

retinol-palmitate USDMF

A retinol-palmitate DMF (Drug Master File) is a document detailing the whole manufacturing process of retinol-palmitate active pharmaceutical ingredient (API) in detail. Different forms of retinol-palmitate DMFs exist exist since differing nations have different regulations, such as retinol-palmitate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A retinol-palmitate DMF submitted to regulatory agencies in the US is known as a USDMF. retinol-palmitate USDMF includes data on retinol-palmitate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The retinol-palmitate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of retinol-palmitate suppliers with USDMF on PharmaCompass.

retinol-palmitate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The retinol-palmitate Drug Master File in Japan (retinol-palmitate JDMF) empowers retinol-palmitate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the retinol-palmitate JDMF during the approval evaluation for pharmaceutical products. At the time of retinol-palmitate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of retinol-palmitate suppliers with JDMF on PharmaCompass.

retinol-palmitate GMP

retinol-palmitate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of retinol-palmitate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right retinol-palmitate GMP manufacturer or retinol-palmitate GMP API supplier for your needs.

retinol-palmitate CoA

A retinol-palmitate CoA (Certificate of Analysis) is a formal document that attests to retinol-palmitate's compliance with retinol-palmitate specifications and serves as a tool for batch-level quality control.

retinol-palmitate CoA mostly includes findings from lab analyses of a specific batch. For each retinol-palmitate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

retinol-palmitate may be tested according to a variety of international standards, such as European Pharmacopoeia (retinol-palmitate EP), retinol-palmitate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (retinol-palmitate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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