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Chemistry

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Also known as: Pt-2385, 1672665-49-4, Pt2385, 6o16716dxp, (s)-3-((2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1h-inden-4-yl)oxy)-5-fluorobenzonitrile, 3-[[(1s)-2,2-difluoro-1-hydroxy-7-methylsulfonyl-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrile
Molecular Formula
C17H12F3NO4S
Molecular Weight
383.3  g/mol
InChI Key
ONBSHRSJOPSEGS-INIZCTEOSA-N
FDA UNII
6O16716DXP

PT-2385
PT-2385 is under investigation in clinical trial NCT03108066 (PT2385 for the Treatment of Von Hippel-lindau Disease-associated Clear Cell Renal Cell Carcinoma).
1 2D Structure

PT-2385

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[[(1S)-2,2-difluoro-1-hydroxy-7-methylsulfonyl-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrile
2.1.2 InChI
InChI=1S/C17H12F3NO4S/c1-26(23,24)14-3-2-13(12-7-17(19,20)16(22)15(12)14)25-11-5-9(8-21)4-10(18)6-11/h2-6,16,22H,7H2,1H3/t16-/m0/s1
2.1.3 InChI Key
ONBSHRSJOPSEGS-INIZCTEOSA-N
2.1.4 Canonical SMILES
CS(=O)(=O)C1=C2C(C(CC2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)(F)F)O
2.1.5 Isomeric SMILES
CS(=O)(=O)C1=C2[C@@H](C(CC2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)(F)F)O
2.2 Other Identifiers
2.2.1 UNII
6O16716DXP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3-((2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1h-inden-4-yl)oxy)-5-fluorobenzonitrile

2. Pt2385

2.3.2 Depositor-Supplied Synonyms

1. Pt-2385

2. 1672665-49-4

3. Pt2385

4. 6o16716dxp

5. (s)-3-((2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1h-inden-4-yl)oxy)-5-fluorobenzonitrile

6. 3-[[(1s)-2,2-difluoro-1-hydroxy-7-methylsulfonyl-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrile

7. 3-(((1s)-2,2-difluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1hinden-4-yl)oxy)-5-fluorobenzonitrile

8. Benzonitrile, 3-(((1s)-2,2-difluoro-2,3-dihydro-1-hydroxy-7-(methylsulfonyl)-1h-inden-4-yl)oxy)-5-fluoro-

9. 79a

10. Unii-6o16716dxp

11. Chembl4173075

12. Schembl16555810

13. Bdbm373008

14. Ex-a2855

15. Us9896418, Compound 163

16. Nsc787312

17. S8352

18. Zb1597

19. Zinc230453533

20. Nsc-787312

21. Ncgc00387306-02

22. Ac-36340

23. Bs-16188

24. Hy-12867

25. D83665

26. A930106

27. Q27456687

2.4 Create Date
2015-05-04
3 Chemical and Physical Properties
Molecular Weight 383.3 g/mol
Molecular Formula C17H12F3NO4S
XLogP32.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass383.04391352 g/mol
Monoisotopic Mass383.04391352 g/mol
Topological Polar Surface Area95.8 Ų
Heavy Atom Count26
Formal Charge0
Complexity686
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 1672665-49-4 / PT-2385 API manufacturers, exporters & distributors?

PT-2385 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of PT-2385 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right PT-2385 manufacturer or PT-2385 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred PT-2385 manufacturer or PT-2385 supplier.

PharmaCompass also assists you with knowing the PT-2385 API Price utilized in the formulation of products. PT-2385 API Price is not always fixed or binding as the PT-2385 Price is obtained through a variety of data sources. The PT-2385 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

PT-2385

Synonyms

1672665-49-4, Pt2385, 6o16716dxp, (s)-3-((2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1h-inden-4-yl)oxy)-5-fluorobenzonitrile, 3-[[(1s)-2,2-difluoro-1-hydroxy-7-methylsulfonyl-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrile, 3-(((1s)-2,2-difluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1hinden-4-yl)oxy)-5-fluorobenzonitrile

Cas Number

1672665-49-4

Unique Ingredient Identifier (UNII)

6O16716DXP

About PT-2385

PT-2385 is under investigation in clinical trial NCT03108066 (PT2385 for the Treatment of Von Hippel-lindau Disease-associated Clear Cell Renal Cell Carcinoma).

PT-2385 Manufacturers

A PT-2385 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of PT-2385, including repackagers and relabelers. The FDA regulates PT-2385 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. PT-2385 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

PT-2385 Suppliers

A PT-2385 supplier is an individual or a company that provides PT-2385 active pharmaceutical ingredient (API) or PT-2385 finished formulations upon request. The PT-2385 suppliers may include PT-2385 API manufacturers, exporters, distributors and traders.

PT-2385 GMP

PT-2385 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of PT-2385 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right PT-2385 GMP manufacturer or PT-2385 GMP API supplier for your needs.

PT-2385 CoA

A PT-2385 CoA (Certificate of Analysis) is a formal document that attests to PT-2385's compliance with PT-2385 specifications and serves as a tool for batch-level quality control.

PT-2385 CoA mostly includes findings from lab analyses of a specific batch. For each PT-2385 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

PT-2385 may be tested according to a variety of international standards, such as European Pharmacopoeia (PT-2385 EP), PT-2385 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (PT-2385 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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