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Also known as: 179474-85-2, Resolor, Prucalopride succinat, Prucalopride (succinate), R-108512, Butanedioic acid 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide
Molecular Formula
C22H32ClN3O7
Molecular Weight
486.0  g/mol
InChI Key
QZRSNVSQLGRAID-UHFFFAOYSA-N
FDA UNII
4V2G75E1CK

Prucalopride Succinate
1 2D Structure

Prucalopride Succinate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide;butanedioic acid
2.1.2 InChI
InChI=1S/C18H26ClN3O3.C4H6O4/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14;5-3(6)1-2-4(7)8/h11-12H,2-10,20H2,1H3,(H,21,23);1-2H2,(H,5,6)(H,7,8)
2.1.3 InChI Key
QZRSNVSQLGRAID-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl.C(CC(=O)O)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
4V2G75E1CK
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-amino-5-chloro-n-(1-(3-methoxypropyl)-4-piperidinyl)-2,3-dihydro-1-benzofuran-7-carboxamide

2. Motegrity

3. Prucalopride

4. R 093877

5. R093877

6. Resolor

7. Resotran

8. Resotrans

2.3.2 Depositor-Supplied Synonyms

1. 179474-85-2

2. Resolor

3. Prucalopride Succinat

4. Prucalopride (succinate)

5. R-108512

6. Butanedioic Acid 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide

7. Prucalopride Succinate [usan]

8. Prucalopride (as Succinate)

9. 4v2g75e1ck

10. 179474-85-2 (succinate)

11. 4-amino-5-chloro-n-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide Succinate

12. Butanedioic Acid, Compd. With 4-amino-5-chloro-2,3-dihydro-n-(1-(3-methoxypropyl)-4-piperidinyl)-7-benzofurancarboxamide (1:1)

13. Butanedioic Acid, Compd. With 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1)

14. Prucalopride Succinate (usan)

15. Resotran

16. 4-amino-5-chloro-n-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide;butanedioic Acid

17. Resolor (tn)

18. Unii-4v2g75e1ck

19. R-93877

20. Resolor Succinate

21. Motegrity (tn)

22. Prucalopridesuccinate

23. R 108512

24. Mls006011219

25. Schembl1230437

26. Chembl2105748

27. Dtxsid701027749

28. Hms3652b21

29. Hms3885j13

30. Bcp09320

31. Mfcd00948731

32. S4247

33. Akos015994741

34. Prucalopride Succinate [mart.]

35. Ccg-269590

36. Cs-3907

37. Ks-1283

38. Prucalopride Succinate [who-dd]

39. 4-amino-5-chloro-n-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide,butanedioic Acid

40. Ac-29960

41. Butanedioic Acid 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarb

42. Hy-12694

43. Smr004702981

44. Db-065276

45. Prucalopride Succinate [orange Book]

46. Ft-0745512

47. Sw219198-1

48. D10152

49. A812449

50. J-519956

51. Q27260539

52. B0084-470898

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 486.0 g/mol
Molecular Formula C22H32ClN3O7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count9
Exact Mass485.1928781 g/mol
Monoisotopic Mass485.1928781 g/mol
Topological Polar Surface Area151 Ų
Heavy Atom Count33
Formal Charge0
Complexity538
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Indication

Resolor is indicated for symptomatic treatment of chronic constipation in adults in whom laxatives fail to provide adequate relief.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Laxatives

Agents that produce a soft formed stool, and relax and loosen the bowels, typically used over a protracted period, to relieve CONSTIPATION. (See all compounds classified as Laxatives.)


Serotonin 5-HT4 Receptor Agonists

Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT4 RECEPTORS. (See all compounds classified as Serotonin 5-HT4 Receptor Agonists.)


5.2 ATC Code

A06AX05


Listed Suppliers

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01

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Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

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Prucalopride Succinate

About the Company : Biophore, founded in 2007, has established itself as a reliable partner in the development and manufacturing of niche and complex pharmaceutical products. With 4 USFDA and EU-appro...

Biophore, founded in 2007, has established itself as a reliable partner in the development and manufacturing of niche and complex pharmaceutical products. With 4 USFDA and EU-approved API manufacturing facilities, a dedicated intermediate facility, and a R&D laboratory housing 400 scientists, Biophore has positioned itself as a global leader among API companies. It consistently ranks among the top 10 US DMF filers and has obtained over 150 patents worldwide in process and polymorph areas. Biophore's facilities have an impressive track record of successful audits by regulatory bodies such as USFDA, EMEA, ANVISA, COFEPRIS, and WHO GMP.
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Alven Laboratories

Czech Republic
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Virtual BoothTrusted Partner for Innovative, Sustainable, and High-Quality API Development and Production.

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Prucalopride

About the Company : Alven Laboratories is a pharmaceutical company specializing in the development, scale-up, and production of original and generic Active Pharmaceutical Ingredients (APIs). With expe...

Alven Laboratories is a pharmaceutical company specializing in the development, scale-up, and production of original and generic Active Pharmaceutical Ingredients (APIs). With expertise in complex molecule chemistry and organic synthesis, we offer cost-efficient, technologically advanced solutions. Our cGMP-compliant facility ensures high production efficiency with a focus on environmental sustainability. From early-stage development to market approvals and commercial production, we provide reliable, flexible, and high-quality services, making us a trusted partner in the pharmaceutical industry.
AlvenLab

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LGM Pharma

U.S.A
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Virtual BoothLGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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Prucalopride Succinate

About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
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04

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Virtual BoothMetrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

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Prucalopride Succinate

About the Company : Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product gro...

Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product groups and has been approved by ISO 9001-2015, USFDA, WHO GMP, Cofepris & Japanese authorities. Metrochem’s in-depth industry knowledge, & hi-tech & advanced infrastructure, helps it provide quality products to its customers. Note: None of the products will be supplied to the countries where this could conflict with existing patents. Further, any products under patent will be offered for R&D purposes only. However, the final responsibility lies with the buyer
Metrochem

05

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Virtual BoothNuray is an expert in the synthesis of Niche novel APIs, the first to launch Generics, NCEs, Advanced Intermediates // USFDA certified.

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Prucalopride Succinate

About the Company : Established in 2012, Nuray Chemicals Pvt Ltd is an API manufacturer for highly regulated markets. Its manufacturing facility with state-of-the-art R&D is located near Chennai in th...

Established in 2012, Nuray Chemicals Pvt Ltd is an API manufacturer for highly regulated markets. Its manufacturing facility with state-of-the-art R&D is located near Chennai in the Indian state of Tamil Nadu. Nuray’s expertise and experience lie in developing the chemistry requirements of the pharmaceutical industry, including the synthesis of NCEs, impurities, metabolites, method development, advanced intermediates and APIs for commercial launch. With its focus on maintaining the highest levels of quality, reliability and transparency, Nuray has emerged as a trusted partner in the global generic market.
Nuray Chemicals

06

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Virtual BoothDeccan Nutraceuticals: A global leader in the integrated development, manufacturing, and marketing of pharmaceutical products.

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Prucalopride Succinate

About the Company : Deccan Nutraceuticals Pvt. Ltd. (DNPL) is a group company of Alkaloids Corporation (India), was founded in 2001 and operates from a 22,000 sq. m. facility in Pune (India). Their co...

Deccan Nutraceuticals Pvt. Ltd. (DNPL) is a group company of Alkaloids Corporation (India), was founded in 2001 and operates from a 22,000 sq. m. facility in Pune (India). Their commitment to quality and adherence to Current Good Manufacturing Practices (CGMP) are integral to their operations. The company has been successfully audited by USFDA (5 times) and EDQM (2 times). The company manufactures high quality phytochemicals, semi-synthetic and synthetic APIs. DNPL stands as a responsible pharmaceutical manufacturer, devoted to delivering premium products across all the regions we serve.
Deccan Nutraceuticals

07

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Virtual BoothHRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

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Prucalopride Succinate

About the Company : HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It...

HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It offers services such as sourcing, manufacturing & supply, helping partners enter new markets worldwide. Its strong partnerships with major players in the pharma and food additive industries help HRV Global effectively promote projects and products. HRV Global represents over 30 large Indian drugmakers, primarily targeting Europe, the US & the Middle East markets. Headquartered in India, HRV Global has offices in the US, Switzerland, Dubai, Lithuania & Turkey.
HRV Global Life Sciences

08

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Virtual BoothShandong Loncom is an R&D-focused manufacturer of Anti-cancer APIs.

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Prucalopride Succinate

About the Company : Established in May 2012, Shandong Loncom Pharmaceutical operates as a fully owned subsidiary of Shandong Bestcomm Pharmaceutical Co., Ltd. Situated in the Qihe Economic Development...

Established in May 2012, Shandong Loncom Pharmaceutical operates as a fully owned subsidiary of Shandong Bestcomm Pharmaceutical Co., Ltd. Situated in the Qihe Economic Development Zone, Shandong Province, Shandong Loncom has operational API pilot tests and production bases adhering to international standards. With 13 production lines dedicated to oral solid preparations, oral liquid preparations and API, it is actively expanding its preparation workshops for small-volume injections, soft capsules, eye drops, topical medicines and innovative drug R&D centres.
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09

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Prucalopride succinate

About the Company : Aspire group was established in the year 2000 with a motto of quality drug for better health of all. In its journey till date, aspire has developed enormous reputation, consistent ...

Aspire group was established in the year 2000 with a motto of quality drug for better health of all. In its journey till date, aspire has developed enormous reputation, consistent growth, unique technologies and world class quality healthcare products. Aspire is pioneer in manufacturing and sourcing unique healthcare products. True to the statement, “Where the future started yesterday” with a foresight on the current trends in the healthcare market, Aspire has grown from strength combining its research strength, Human resources and well established quality systems. Aspire has crossed numerous milestones in a comparatively short period since its inception.
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Prucalopride Succinate

About the Company : Founded in 1986 by Mr. P.V. Ramaprasad Reddy, Mr. K. Nityananda Reddy and a small group of highly committed professionals, Aurobindo Pharma was born off a vision. The company comme...

Founded in 1986 by Mr. P.V. Ramaprasad Reddy, Mr. K. Nityananda Reddy and a small group of highly committed professionals, Aurobindo Pharma was born off a vision. The company commenced operations in 1988-89 with a single unit manufacturing Semi-Synthetic Penicillin (SSP) at Pondicherry. Aurobindo Pharma became a public company in 1992 and listed its shares in the Indian stock exchanges in 1995. In addition to being the market leader in Semi-Synthetic Penicillins, it has a presence in key therapeutic segments such as neurosciences, cardiovascular, anti-retrovirals, anti-diabetics, gastroenterology and cephalosporins, among others.
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11-Jan-2022
03-May-2025
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ABOUT THIS PAGE

Looking for 179474-85-2 / Prucalopride Succinate API manufacturers, exporters & distributors?

Prucalopride Succinate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Prucalopride Succinate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Prucalopride Succinate manufacturer or Prucalopride Succinate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Prucalopride Succinate manufacturer or Prucalopride Succinate supplier.

PharmaCompass also assists you with knowing the Prucalopride Succinate API Price utilized in the formulation of products. Prucalopride Succinate API Price is not always fixed or binding as the Prucalopride Succinate Price is obtained through a variety of data sources. The Prucalopride Succinate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Prucalopride Succinate

Synonyms

179474-85-2, Resolor, Prucalopride succinat, Prucalopride (succinate), R-108512, Butanedioic acid 4-amino-5-chloro-2,3-dihydro-n-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide

Cas Number

179474-85-2

Unique Ingredient Identifier (UNII)

4V2G75E1CK

Prucalopride Succinate Manufacturers

A Prucalopride Succinate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Prucalopride Succinate, including repackagers and relabelers. The FDA regulates Prucalopride Succinate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Prucalopride Succinate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Prucalopride Succinate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Prucalopride Succinate Suppliers

A Prucalopride Succinate supplier is an individual or a company that provides Prucalopride Succinate active pharmaceutical ingredient (API) or Prucalopride Succinate finished formulations upon request. The Prucalopride Succinate suppliers may include Prucalopride Succinate API manufacturers, exporters, distributors and traders.

click here to find a list of Prucalopride Succinate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Prucalopride Succinate USDMF

A Prucalopride Succinate DMF (Drug Master File) is a document detailing the whole manufacturing process of Prucalopride Succinate active pharmaceutical ingredient (API) in detail. Different forms of Prucalopride Succinate DMFs exist exist since differing nations have different regulations, such as Prucalopride Succinate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Prucalopride Succinate DMF submitted to regulatory agencies in the US is known as a USDMF. Prucalopride Succinate USDMF includes data on Prucalopride Succinate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Prucalopride Succinate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Prucalopride Succinate suppliers with USDMF on PharmaCompass.

Prucalopride Succinate KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Prucalopride Succinate Drug Master File in Korea (Prucalopride Succinate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Prucalopride Succinate. The MFDS reviews the Prucalopride Succinate KDMF as part of the drug registration process and uses the information provided in the Prucalopride Succinate KDMF to evaluate the safety and efficacy of the drug.

After submitting a Prucalopride Succinate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Prucalopride Succinate API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Prucalopride Succinate suppliers with KDMF on PharmaCompass.

Prucalopride Succinate WC

A Prucalopride Succinate written confirmation (Prucalopride Succinate WC) is an official document issued by a regulatory agency to a Prucalopride Succinate manufacturer, verifying that the manufacturing facility of a Prucalopride Succinate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Prucalopride Succinate APIs or Prucalopride Succinate finished pharmaceutical products to another nation, regulatory agencies frequently require a Prucalopride Succinate WC (written confirmation) as part of the regulatory process.

click here to find a list of Prucalopride Succinate suppliers with Written Confirmation (WC) on PharmaCompass.

Prucalopride Succinate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Prucalopride Succinate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Prucalopride Succinate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Prucalopride Succinate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Prucalopride Succinate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Prucalopride Succinate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Prucalopride Succinate suppliers with NDC on PharmaCompass.

Prucalopride Succinate GMP

Prucalopride Succinate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Prucalopride Succinate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Prucalopride Succinate GMP manufacturer or Prucalopride Succinate GMP API supplier for your needs.

Prucalopride Succinate CoA

A Prucalopride Succinate CoA (Certificate of Analysis) is a formal document that attests to Prucalopride Succinate's compliance with Prucalopride Succinate specifications and serves as a tool for batch-level quality control.

Prucalopride Succinate CoA mostly includes findings from lab analyses of a specific batch. For each Prucalopride Succinate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Prucalopride Succinate may be tested according to a variety of international standards, such as European Pharmacopoeia (Prucalopride Succinate EP), Prucalopride Succinate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Prucalopride Succinate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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