Prestwick3_000896

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

2 API Suppliers, 2 Listed Suppliers

DEVELOPMENTS

6 Drug(s) in Development

6 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Imports

DOSSIERs // Finished Dosage Formulations

1 Dossiers, 1 Listed Dossiers

ANALYTICAL SOLUTION(s)

1 Other Ref. Standards

1 Other Ref. Standards

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

459

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 1188-21-2, Acetyl-l-leucine, Ac-leu-oh, N-acetylleucine, L-acetylleucine, (s)-2-acetamido-4-methylpentanoic acid

Molecular Formula

C₈H₁₅NO₃

Molecular Weight

173.21 g/mol

InChI Key

WXNXCEHXYPACJF-ZETCQYMHSA-N

FDA UNII

E915HL7K2O

N-acetyl-leu is a natural product found in Mus musculus, Euglena gracilis, and other organisms with data available.

1 2D Structure

Prestwick3_000896

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S)-2-acetamido-4-methylpentanoic acid

2.1.2 InChI

InChI=1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1

2.1.3 InChI Key

WXNXCEHXYPACJF-ZETCQYMHSA-N

2.1.4 Canonical SMILES

CC(C)CC(C(=O)O)NC(=O)C

2.1.5 Isomeric SMILES

CC(C)C[C@@H](C(=O)O)NC(=O)C

2.2 Other Identifiers

2.2.1 UNII

E915HL7K2O

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Acetyl-dl-leucine

2. Acetylleucine

3. Acetylleucine, L-

4. Lasdol

5. N-acetylleucine

6. Tanganil

2.3.2 Depositor-Supplied Synonyms

1. 1188-21-2

2. Acetyl-l-leucine

3. Ac-leu-oh

4. N-acetylleucine

5. L-acetylleucine

6. (s)-2-acetamido-4-methylpentanoic Acid

7. N-acetyl-leucine

8. Leucine, N-acetyl-, L-

9. (2s)-2-acetamido-4-methylpentanoic Acid

10. Leucine, N-acetyl-

11. (s)-2-acetylamino-4-methyl-pentanoic Acid

12. N-acetyl-l-leucin

13. L-leucine, N-acetyl-

14. Nsc 206316

15. E915hl7k2o

16. (2s)-2-(acetylamino)-4-methylpentanoic Acid

17. Chebi:17786

18. Cas-1188-21-2

19. Mfcd00065131

20. Dsstox_cid_25870

21. Dsstox_rid_81188

22. Dsstox_gsid_45870

23. N-acetyl-leu

24. Unii-e915hl7k2o

25. Acetyl-leucine

26. N-acetyl Leucine

27. Nsc-206316

28. Ncgc00094935-01

29. Einecs 214-706-3

30. Nall

31. N-acetyl-(l)-leucine

32. Spectrum_001313

33. (2s)-2-acetamido-4-methyl-pentanoic Acid

34. Maybridge1_002565

35. Prestwick0_000896

36. Prestwick1_000896

37. Prestwick2_000896

38. Prestwick3_000896

39. Spectrum2_000475

40. Spectrum3_001480

41. Spectrum4_000036

42. Spectrum5_001242

43. Acetylleucine, L-

44. Acetylleucine, (s)-

45. Bspbio_000712

46. Bspbio_003039

47. Kbiogr_000471

48. Kbioss_001793

49. Chembl56021

50. Divk1c_000622

51. Divk1c_001317

52. Schembl282372

53. Spectrum1502001

54. Spbio_000610

55. Spbio_002921

56. Bpbio1_000784

57. Dtxsid6045870

58. Hms501p04

59. Hms548m13

60. Kbio1_000622

61. Kbio2_001793

62. Kbio2_004361

63. Kbio2_006929

64. Kbio3_002539

65. N-acetyl-l-(-)-leucine

66. Ninds_000622

67. Hms1570d14

68. Hms1921b16

69. Hms2097d14

70. Hms3714d14

71. Pharmakon1600-01502001

72. Zinc135384

73. Act06842

74. Tox21_111362

75. Ccg-40254

76. N-acetyl-l-leucine [usp-rs]

77. Nsc758152

78. S3109

79. Akos000302149

80. Akos010400978

81. Tox21_111362_1

82. Fd20066

83. Cds1_000277

84. Idi1_000622

85. Ncgc00016567-01

86. Ncgc00016567-02

87. Ncgc00016567-03

88. Ncgc00016567-05

89. Ac-22375

90. Hy-59291

91. Ms-20482

92. Sbi-0051693.p002

93. N-acetyl-l-leucine, Reagentplus(r), 99%

94. A0098

95. Ab00513952

96. Am20080126

97. Bb 0256992

98. Cs-0007651

99. A-1460

100. A16391

101. C02710

102. M03063

103. Ab00052251_03

104. 188a212

105. N-acetyl-l-leucine, Vetec(tm) Reagent Grade, 98%

106. Brd-k27406233-001-05-1

107. Q63395724

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₈H₁₅NO₃
Molecular Weight	173.21 g/mol
XLogP3	0.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	173.10519334 g/mol
Monoisotopic Mass	173.10519334 g/mol
Topological Polar Surface Area	66.4 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	177
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1