Prestwick3_000627

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

39 API Suppliers, 7 USDMF, 3 CEP/COS, 2 JDMF, 1 EU WC, 3 NDC API, 33 Listed Suppliers

DEVELOPMENTS

2 Drug(s) in Development

2 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Exports, FDF Imports

INTERMEDIATES

2 Suppliers

2 Suppliers

DOSSIERs // Finished Dosage Formulations

290 Dossiers, 57 FDA Orange Book, 48 Europe, 14 Canada, 7 Australia, 33 South Africa, 131 Listed Dossiers

DRUG PRODUCT COMPOSITION

FOR SOLUTION;INTRAVENOUS - 80MG/VIAL;0.02MG/VIAL;0.001MG/VIAL;5MG/VIAL;0.01MG/VIAL;0.14MG/VIAL;17MG/VIAL;0.2MG/VIAL;1MG/VIAL;1.4MG/VIAL;EQ 1.2MG BASE/VIAL;0.7MG/VIAL;7MG/VIAL, SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;0.03MG/ML, SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;30MCG/ML, INJECTABLE;INTRAVENOUS - 200MG/VIAL;0.06MG/VIAL;0.005MG/VIAL;15MG/VIAL;0.005MG/VIAL;0.6MG/VIAL;40MG/VIAL;6MG/VIAL;3.6MG/VIAL;6MG/VIAL;1MG/VIAL;10MG/VIAL;0.15MG/VIAL, INJECTABLE;INJECTION - 20MG/ML;0.006MG/ML;0.05MCG/ML;1.5MG/ML;0.0005MG/ML;0.06MG/ML;4MG/ML;0.6MG/ML;0.36MG/ML;0.6MG/ML;0.1MG/ML;1MG/ML

FOR SOLUTION;INTRAVENOUS - 80MG/VIAL;0.02MG/VIAL;0.001MG/VIAL;5MG/VIAL;0.01MG/VIAL;0.14MG/VIAL;17MG/VIAL;0.2MG/VIAL;1MG/VIAL;1.4MG/VIAL;EQ 1.2MG BASE/VIAL;0.7MG/VIAL;7MG/VIAL
SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;0.03MG/ML
SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;30MCG/ML
INJECTABLE;INTRAVENOUS - 200MG/VIAL;0.06MG/VIAL;0.005MG/VIAL;15MG/VIAL;0.005MG/VIAL;0.6MG/VIAL;40MG/VIAL;6MG/VIAL;3.6MG/VIAL;6MG/VIAL;1MG/VIAL;10MG/VIAL;0.15MG/VIAL
INJECTABLE;INJECTION - 20MG/ML;0.006MG/ML;0.05MCG/ML;1.5MG/ML;0.0005MG/ML;0.06MG/ML;4MG/ML;0.6MG/ML;0.36MG/ML;0.6MG/ML;0.1MG/ML;1MG/ML

RELATED EXCIPIENT COMPANIES

Suppliers, 41 Roquette, 39 Kerry, 39 BASF, 23 Microlex e.U, 22 SPI Pharma, 16 Corel Pharma Chem, 16 Seppic, 14 Gangwal Chemicals, 14 Actylis, 13 Gangwal Healthcare, 13 Nanjing Well Pharmaceutical, 12 Sigachi Industries, 11 Ideal Cures Pvt Ltd, 11 Rochem International Inc, 10 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 8 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 8 DKSH, 7 Boai NKY Pharmaceuticals Ltd, 7 DFE Pharma, 6 Lonza Capsugel, 5 Kima Chemical, 5 Vasa Pharmachem, 5 Ingredion Pharma Solutions, 4 The Dow Chemical Company, 4 Pharmatrans-Sanaq, 4 ACG Worldwide, 4 Prachin Chemical, 3 Finar, 3 Shijiazhuang Huaxu Pharmaceutical, 3 Aeon Procare, 3 Doshion Polyscience, 3 Evonik, 3 Ulanqab Kema New Material, 2 Zhejiang Huakang Pharmaceutical, 2 Kewpie Corporation, 2 Clariant, 2 Jai Radhe Sales, 2 Qualicaps, 2 Pfanstiehl, 2 Alcedo Pharmachem, 2 Nomisma Healthcare, 2 Seqens, 1 Avesta Pharma, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 1 Bioplus Life Sciences, 1 Pharm-RX Chemical, 1 Nanjing Bold Chemical

EXCIPIENTS BY APPLICATIONS

108 Fillers, Diluents & Binders, 73 Coating Systems & Additives, 51 Direct Compression, 47 Controlled & Modified Release, 46 Solubilizers, 45 Disintegrants & Superdisintegrants, 41 Taste Masking, 35 Parenteral, 35 Thickeners and Stabilizers, 33 Granulation, 29 Topical, 28 Film Formers & Plasticizers, 25 Lubricants & Glidants, 23 Chewable & Orodispersible Aids, 17 Co-Processed Excipients, 14 Emulsifying Agents, 10 API Stability Enhancers, 9 Empty Capsules, 8 Rheology Modifiers, 5 Surfactant & Foaming Agents, 4 Vegetarian Capsules, 2 Coloring Agents, 1 Soft Gelatin

GLOBAL SALES INFORMATION

7 US Medicaid Prescriptions, 34 Finished Drug Prices

MARKET PLACE

52 APIs, 8 DOSSIERS // FDF

ANALYTICAL SOLUTION(s)

1 Analytical Solutions, 3 EDQM Standards, 3 USP Standards, 4 JP Standards, 7 Other Ref. Standards

DIGITAL CONTENT

17 News

17 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

146

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

131

GLOBAL SALES (USD Million)

U.S. Medicaid

4.00

Annual Reports

FDF Market Place

EXCIPIENTS

403

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as:

Molecular Formula

C₁₉H₁₉N₇O₆

Molecular Weight

441.4 g/mol

InChI Key

OVBPIULPVIDEAO-LBPRGKRZSA-N

1 2D Structure

Prestwick3_000627

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

2.1.2 InChI

InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

2.1.3 InChI Key

OVBPIULPVIDEAO-LBPRGKRZSA-N

2.1.4 Canonical SMILES

C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N

2.1.5 Isomeric SMILES

C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N

2.2 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₁₉N₇O₆
Molecular Weight	441.4 g/mol
XLogP3	-1.1
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	9
Exact Mass	441.13968135 g/mol
Monoisotopic Mass	441.13968135 g/mol
Topological Polar Surface Area	209 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	767
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Folic acid
PubMed Health	Folic Acid
Drug Classes	Nutriceutical, Nutritive Agent
Drug Label	Folic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridiny)methyl]amino]benzoyl]-L-glutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by a peptide linkage to glutamic aci...
Active Ingredient	Folic acid
Dosage Form	Tablet; Injectable
Route	Injection; Oral
Strength	1 mg; 1mg; 5mg/ml
Market Status	Prescription
Company	Bicon Pharm; Excellium; Jubilant Cadista; Cadila Pharms; Invagen Pharms; Hikma Pharms; Watson Labs; Amneal Pharm; Fresenius Kabi Usa; Vintage; Contract Pharmacal

2 of 2
Drug Name	Folic acid
PubMed Health	Folic Acid
Drug Classes	Nutriceutical, Nutritive Agent
Drug Label	Folic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridiny)methyl]amino]benzoyl]-L-glutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by a peptide linkage to glutamic aci...
Active Ingredient	Folic acid
Dosage Form	Tablet; Injectable
Route	Injection; Oral
Strength	1 mg; 1mg; 5mg/ml
Market Status	Prescription
Company	Bicon Pharm; Excellium; Jubilant Cadista; Cadila Pharms; Invagen Pharms; Hikma Pharms; Watson Labs; Amneal Pharm; Fresenius Kabi Usa; Vintage; Contract Pharmacal

Find Folic Acid manufacturers, exporters & distributors on PharmaCompass

Prestwick3_000627

Prestwick3_000627

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

39 API Suppliers

7 USDMF

3 CEP/COS

2 JDMF

1 EU WC

3 NDC API

33 Listed Suppliers

DEVELOPMENTS

2 Drug(s) in Development

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Exports

FDF Imports

INTERMEDIATES

2 Suppliers

DOSSIERs // Finished Dosage Formulations

290 Dossiers

57 FDA Orange Book

48 Europe

14 Canada

7 Australia

33 South Africa

131 Listed Dossiers

DRUG PRODUCT COMPOSITION

FOR SOLUTION;INTRAVENOUS - 80MG/VIAL;0.02MG/VIAL;0.001MG/VIAL;5MG/VIAL;0.01MG/VIAL;0.14MG/VIAL;17MG/VIAL;0.2MG/VIAL;1MG/VIAL;1.4MG/VIAL;EQ 1.2MG BASE/VIAL;0.7MG/VIAL;7MG/VIAL

SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;0.03MG/ML

SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;30MCG/ML

INJECTABLE;INTRAVENOUS - 200MG/VIAL;0.06MG/VIAL;0.005MG/VIAL;15MG/VIAL;0.005MG/VIAL;0.6MG/VIAL;40MG/VIAL;6MG/VIAL;3.6MG/VIAL;6MG/VIAL;1MG/VIAL;10MG/VIAL;0.15MG/VIAL

INJECTABLE;INJECTION - 20MG/ML;0.006MG/ML;0.05MCG/ML;1.5MG/ML;0.0005MG/ML;0.06MG/ML;4MG/ML;0.6MG/ML;0.36MG/ML;0.6MG/ML;0.1MG/ML;1MG/ML

RELATED EXCIPIENT COMPANIES

Suppliers

41 Roquette

39 Kerry

39 BASF

23 Microlex e.U

22 SPI Pharma

16 Corel Pharma Chem

16 Seppic

14 Gangwal Chemicals

14 Actylis

13 Gangwal Healthcare

13 Nanjing Well Pharmaceutical

12 Sigachi Industries

11 Ideal Cures Pvt Ltd

11 Rochem International Inc

10 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

8 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

8 DKSH

7 Boai NKY Pharmaceuticals Ltd

7 DFE Pharma

6 Lonza Capsugel

5 Kima Chemical

5 Vasa Pharmachem

5 Ingredion Pharma Solutions

4 The Dow Chemical Company

4 Pharmatrans-Sanaq

4 ACG Worldwide

4 Prachin Chemical

3 Finar

3 Shijiazhuang Huaxu Pharmaceutical

3 Aeon Procare

3 Doshion Polyscience

3 Evonik

3 Ulanqab Kema New Material

2 Zhejiang Huakang Pharmaceutical

2 Kewpie Corporation

2 Clariant

2 Jai Radhe Sales

2 Qualicaps

2 Pfanstiehl

2 Alcedo Pharmachem

2 Nomisma Healthcare