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1. Dcontractyl
2. Dolo Visano M
1. 59-47-2
2. Cresoxydiol
3. Decontractyl
4. Memphenesin
5. Mephenesine
6. Mephedan
7. Lissephen
8. Tolserol
9. Anatensin
10. Cresodiol
11. Decontractil
12. Dioloxol
13. Lissenphan
14. Mefenesina
15. Mephelor
16. Mephesin
17. Myodetensin
18. Myodetensine
19. Atensin
20. Curaril
21. Sinan
22. Kresoxypropandiol
23. Cresoxypropanediol
24. 3-(2-methylphenoxy)propane-1,2-diol
25. Cresossidiolo
26. Curarythan
27. Seconesinz
28. Spartoloxin
29. Spartoloxyn
30. Curythan
31. Daserol
32. Diloxol
33. Dioloxal
34. Findolar
35. Findolor
36. Glukresin
37. Glykresin
38. Glyotol
39. Halabar
40. Kinavosyl
41. Mephate
42. Mepherol
43. Mephosal
44. Mephson
45. Mervaldin
46. Mianesina
47. Miolisina
48. Moctynol
49. Myanesin
50. Myastenin
51. Myocuran
52. Myolysin
53. Myosera
54. Myoserol
55. Myoxane
56. Nembusen
57. Nephelor
58. Noctynol
59. Oranixon
60. Prolaxin
61. Proloxin
62. Relaxant
63. Relaxar
64. Relaxil
65. Relaxyl
66. Renarcol
67. Sansdolor
68. Saserol
69. Spasmolyn
70. Stilalgin
71. Thioxidil
72. Thoxidil
73. Tokerol
74. Tolansin
75. Tolbart
76. Tolhart
77. Tolofren
78. Tolosate
79. Toloxyn
80. Tolulexin
81. Tolulox
82. Tolydrin
83. Tolynol
84. Tolyspaz
85. Torulox
86. Anxine
87. Avesyl
88. Avosyl
89. Avoxil
90. Avoxyl
91. Daserd
92. Glytol
93. Mephin
94. Myanil
95. Myanol
96. Myasin
97. Myolax
98. Myopan
99. Myopen
100. Myopna
101. Myoten
102. Myoxyl
103. Ortol
104. Prolax
105. Temian
106. Tolax
107. Tolcil
108. Tolsil
109. Tolsin
110. Xeral
111. Rhex Regulans
112. Walko-nesin
113. 1,2-propanediol, 3-(2-methylphenoxy)-
114. 3-(2-methylphenoxy)-1,2-propanediol
115. Cresossipropandiolo
116. Rhex 'hobeino'
117. O-cresyl Glycerol Ether
118. Glyceryl O-tolyl Ether
119. Ageflex Cge
120. O-cresol Glyceryl Ether
121. 3-(o-tolyloxy)propane-1,2-diol
122. 1-o-tolylglycerol Ether
123. Mephenesinum
124. Mephensin
125. O-kresol-glycerinaether
126. Byk-m 1
127. 3-o-toloxy-1,2-propanediol
128. 3-(o-methylphenoxy)-1,2-propanediol
129. Bdh 312
130. 1-ortho-tolylglycerol Ether
131. 3-(o-tolyloxy)-1,2-propanediol
132. 3-(2-tolyloxy)-1,2-propanediol
133. Walconesin
134. Mycocuran
135. Tolseron
136. Mc 2303
137. Rp 3602
138. Sq 1156
139. 1,2-dihydroxy-3-(2-methylphenoxy)propane
140. A 1141
141. Nsc-25234
142. Mefensina
143. Rex Regulans
144. 1,2-propanediol, 3-(o-tolyloxy)-
145. Walco-nesin
146. O-cresyl .alpha.-glyceryl Ether
147. .alpha.-(o-tolyl)glyceryl Ether
148. 7b8pir2954
149. Mephenesin (inn)
150. Nsc25234
151. Component Of Tolagesic
152. Ncgc00094908-01
153. Mephenesin [inn]
154. Dsstox_cid_3254
155. 1, 3-(o-tolyloxy)-
156. Dsstox_rid_76942
157. Wln: Q1yq1or B1
158. Dsstox_gsid_23254
159. 1, 3-(2-methylphenoxy)-
160. .alpha.,.beta.-dihydroxy-.gamma.-(2-methylphenoxy)propane
161. Mefenesina [inn-spanish]
162. Mephenesine [inn-french]
163. Mephenesinum [inn-latin]
164. O-cresyl Alpha-glyceryl Ether
165. Alpha-(o-tolyl)glyceryl Ether
166. O-kresol-glycerinaether [german]
167. Sr-05000001772
168. Einecs 200-427-4
169. Nsc 25234
170. Brn 2047373
171. Mephenesin [inn:ban:nf]
172. Rhex
173. Unii-7b8pir2954
174. Cas-59-47-2
175. Tolserol (tn)
176. Prestwick_577
177. Alpha,beta-dihydroxy-gamma-(2-methylphenoxy)propane
178. Mephenesin, 98%
179. 1-(o-tolyl)glycerol
180. 1-(2-tolyl)glycerol
181. Spectrum_001402
182. Mephenesin [mi]
183. Prestwick0_000178
184. Prestwick1_000178
185. Prestwick2_000178
186. Prestwick3_000178
187. Spectrum2_001418
188. Spectrum3_000908
189. Spectrum4_001007
190. Spectrum5_001199
191. (.+/-.)-mephenesin
192. Mephenesin [mart.]
193. 1-(2-methylphenyl)glycerol
194. Mephenesin [who-dd]
195. Schembl25448
196. Bspbio_000075
197. Kbiogr_001473
198. Kbioss_001882
199. Divk1c_000076
200. Spectrum1501140
201. Spbio_001496
202. Spbio_001996
203. Bpbio1_000083
204. Chembl229128
205. Dtxsid4023254
206. Chebi:94398
207. Hms500d18
208. Kbio1_000076
209. Kbio2_001882
210. Kbio2_004450
211. Kbio2_007018
212. Kbio3_001856
213. Nsc8134
214. Ninds_000076
215. Hms1568d17
216. Hms1921j09
217. Hms2092f17
218. Hms2095d17
219. Hms3712d17
220. Hms3886k09
221. Pharmakon1600-01501140
222. Hy-b1283
223. Nsc-8134
224. Nsc36140
225. Nsc50788
226. Glycerol-1-(o-tolyl) Ether
227. Tox21_111356
228. Ccg-38970
229. Mfcd00004718
230. Nsc-36140
231. Nsc-50788
232. Nsc757857
233. S5032
234. Stl430456
235. Akos015912866
236. Tox21_111356_1
237. Cs-5340
238. Db13583
239. Nsc-757857
240. Idi1_000076
241. 1,2-propanediol, 3-(2-methylphenoxy)
242. Ncgc00094908-02
243. Ncgc00094908-03
244. Ncgc00094908-06
245. 3-[(2-methylphenyl)oxy]propane-1,2-diol
246. Sbi-0051654.p002
247. Ab00052216
248. Ft-0628209
249. M3076
250. 3-(2-methylphenoxy)-1,2-propanediol, 98%
251. D02595
252. D97581
253. Ab00052216_04
254. A923330
255. Q3333250
256. Sr-05000001772-1
257. Sr-05000001772-2
258. Sr-05000001772-3
259. Brd-a55469827-001-01-7
| Molecular Weight | 182.22 g/mol |
|---|---|
| Molecular Formula | C10H14O3 |
| XLogP3 | 1.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 182.094294304 g/mol |
| Monoisotopic Mass | 182.094294304 g/mol |
| Topological Polar Surface Area | 49.7 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 138 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Mephenesin was used for the treatment of muscle spasticity in diseases like Parkinson's or Multiple Sclerosis.
Mephenesin reduced neuronal excitability leading to decreases action potentials to muscle fibers which ultimately produces a reduction in spasticity.
Muscle Relaxants, Central
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) (See all compounds classified as Muscle Relaxants, Central.)
M - Musculo-skeletal system
M03 - Muscle relaxants
M03B - Muscle relaxants, centrally acting agents
M03BX - Other centrally acting agents
M03BX06 - Mephenesin
The exact mechanism of action of mephenesin is not known. It has been observed to block both inward sodium and inward calcium currents in neurons. It has a physiological effect which opposes that of strychnine.
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