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Potassium Sulfate
Also known as: 7778-80-5, Dipotassium sulfate, Potassium sulphate, Sulfuric acid dipotassium salt, Sal polychrestum, Sulfuric acid, potassium salt
Molecular Formula
K2O4S
Molecular Weight
174.26  g/mol
InChI Key
OTYBMLCTZGSZBG-UHFFFAOYSA-L
FDA UNII
1K573LC5TV

1 2D Structure

Potassium Sulfate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
dipotassium;sulfate
2.1.2 InChI
InChI=1S/2K.H2O4S/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2
2.1.3 InChI Key
OTYBMLCTZGSZBG-UHFFFAOYSA-L
2.1.4 Canonical SMILES
[O-]S(=O)(=O)[O-].[K+].[K+]
2.2 Other Identifiers
2.2.1 UNII
1K573LC5TV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. K(2)so(4)

2. Potassium Sulfate (1:1)

3. Potassium Sulfate, 35s-labeled

4. Sulfuric Acid, Dipotassium Salt

2.3.2 Depositor-Supplied Synonyms

1. 7778-80-5

2. Dipotassium Sulfate

3. Potassium Sulphate

4. Sulfuric Acid Dipotassium Salt

5. Sal Polychrestum

6. Sulfuric Acid, Potassium Salt

7. Arcanum Duplicatum

8. Sulfuric Acid, Dipotassium Salt

9. Potassiumsulfate

10. Dipotassium;sulfate

11. Tartarus Vitriolatus

12. Kali Sulphuricum

13. Potassium Sulfate (2:1)

14. K2so4

15. Potassium (as Sulfate)

16. Mfcd00011388

17. Sulfuric Acid Potassium Salt (1:2)

18. 10233-01-9

19. 1k573lc5tv

20. Ins No.515(i)

21. Chebi:32036

22. Ins-515(i)

23. E-515(i)

24. Kalium Sulphuricum

25. Caswell No. 702

26. Potassium Sulfate [jan]

27. Sulfato De Potasio

28. Potassium Sulfate (k2(so4))

29. Hsdb 5047

30. Einecs 231-915-5

31. Einecs 233-558-0

32. Epa Pesticide Chemical Code 005603

33. Sulfuric Acid Potassium Salt

34. Unii-1k573lc5tv

35. Kaliumsulfat

36. Potassium Sulfate, Acs

37. Potassium Sulfate [usan:jan]

38. Sulfate Of Potash

39. Potassium Sulfate ,(s)

40. Ec 231-915-5

41. Potassium Sulfate (k2so4)

42. Potassium Sulfate [mi]

43. Kali Sulphuricum [hpus]

44. Potassium Sulfate [fcc]

45. Chembl2021424

46. Dtxsid6029701

47. Potassium Sulfate [hsdb]

48. Potassium Sulfate [inci]

49. Potassium Sulfate [usan]

50. Potassium Sulfate (jp17/usan)

51. Potassium Sulfate [vandf]

52. Potassium Sulfate [mart.]

53. Potassium Sulfate [who-dd]

54. Potassium Sulfate, Biochemical Grade

55. Akos025243249

56. Sulfuric Acid, Potassium Salt (1:?)

57. Db14499

58. Potassium Sulfate [orange Book]

59. Potassium (as Sulfate) [vandf]

60. Potassium Sulfate [ep Monograph]

61. Potassium Sulphate, Containing In The Dry State More Than 52 Per Cent By Weight Of K2o

62. Fishertab™ Mt-37 Kjeldahl Tablets

63. Fishertab™ St-35 Kjeldahl Tablets

64. Fishertab™ St-auto Kjeldahl Tablets

65. Potassium Sulfate, 99.997% (metals Basis)

66. D01726

67. Potassium Sulfate, Trace Metals Grade 99.95%

68. Q193054

69. Suprep Bowel Prep Kit Component Potassium Sulfate

70. Potassium Sulfate Component Of Suprep Bowel Prep Kit

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 174.26 g/mol
Molecular Formula K2O4S
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass173.87914262 g/mol
Monoisotopic Mass173.87914262 g/mol
Topological Polar Surface Area88.6 Ų
Heavy Atom Count7
Formal Charge0
Complexity62.2
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Indication

Potassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions.


5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Osmotic Laxative [EPC]; Potassium Compounds [CS]; Potassium Salt [EPC]; Increased Large Intestinal Motility [PE]
5.2 Absorption, Distribution and Excretion

Route of Elimination

Mostly urine but also skin and feces.


5.3 Mechanism of Action

Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium is maintained by ion pumps in the cell membrane. The cell membrane potential created by potassium and sodium ions allows the cell generate an action potentiala "spike" of electrical discharge. The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function. Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of acidity.


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