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1. Ly2140023 Monohydrate
1. Ly2140023 Monohydrate
2. 956385-05-0
3. Ly-2140023 Monohydrate
4. Pomaglumetad Metionilo
5. We665jb15r
6. (1r,4s,5s,6s)-4-(l-methionylamino)-2-thiabicyclo(3.1.0)hexane-4,6-dicarboxylic Acid 2,2-dioxide Monohydrate
7. Dtxsid00212944
8. 4-(((2s)-2-amino-4-(methylthio)butanoyl)amino)-2-thiabicyclo(3.1.0)hexane-4,6-dicarboxylic Acid 2,2-dioxide Hydrate, 1r,4s,5s,6s
9. Pomaglumetadum Methionilum
10. Refchem:175219
11. Dtxcid30135435
12. 2-thiabicyclo(3.1.0)hexane-4,6-dicarboxylic Acid, 4-(((2s)-2-amino-4-(methylthio)-1-oxobutyl)amino)-, 2,2-dioxide, Hydrate (1:1), (1r,4s,5s,6s)-
13. 691-416-7
14. Pomaglumetad Methionil [usan]
15. Pomaglumetad Methionil (usan)
16. (1r,4s,5s,6s)-4-((s)-2-amino-4-(methylthio)butanamido)-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid 2,2-dioxide Hydrate
17. (1r,4s,5s,6s)-4-[[(2s)-2-amino-4-methylsulfanylbutanoyl]amino]-2,2-dioxo-2lambda6-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid;hydrate
18. Unii-we665jb15r
19. Pomaglumetad Methionil Hydrate
20. Orb1708826
21. Schembl1100180
22. Chembl2105707
23. Dtxsid10241907
24. Pomaglumetad Methionil Monohydrate
25. Akos040735205
26. Hy-105040
27. Cs-0024754
28. D09949
29. Q27292586
30. (1r,4s,5s,6s)-4-(2s-4-methylthio-2-aminobutanonyl)amino-2,2-dioxo-2lambda6-thia- Bicyclo(3.1.0)hexane-4,6-dicarboxylic Acid Monohydrate
31. (1r,4s,5s,6s)-4-(l-methionylamino)-2,2-dioxo-2gamma6-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid-water (1:1)
32. (1r,4s,5s,6s)-4-(l-methionylamino)-2,2-dioxo-2lambda~6~-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid--water (1/1)
33. (1r,4s,5s,6s)-4-[[(2s)-2-amino-4-methylsulfanylbutanoyl]amino]-2,2-dioxo-2
34. E6-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic Acid;hydrate
35. 2-thiabicyclo(3.1.0)hexane-4,6-dicarboxylic Acid, 4-(((2s)-2-amino-4-(methylthio)-1- Oxobutyl)amino)-, 2,2-dioxide, Hydrate (1:1), (1r,4s,5s,6s)-
| Molecular Weight | 384.4 g/mol |
|---|---|
| Molecular Formula | C12H20N2O8S2 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 7 |
| Exact Mass | Da |
| Monoisotopic Mass | Da |
| Topological Polar Surface Area | 199 |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 644 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
Investigated for use/treatment in psychosis and schizophrenia and schizoaffective disorders.
LY2140023 is an antipsychotic agent that is a metabotropic glutamate 2/3 receptor agonist. This agent has a new mechanism of action that is efficacious in treating schizophrenia and potentially other neuropsychiatric conditions. Once absorbed, LY2140023 is efficiently hydrolyzed to produce the active mGlu2/3 receptor agonist LY404039. LY404039 and other mGlu2/3 agonists do not directly interact with dopamine or serotonin (5-HT2A) receptors. However, 'functional' 5-HT2A receptor antagonism in the prefrontal cortex may represent a common mechanism shared by clinically effective atypical antipsychotics and mGlu2/3 receptor agonists, and may contribute to the antipsychotic actions of LY2140023.
ABOUT THIS PAGE
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PharmaCompass offers a list of Pomaglumetad Methionil API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Pomaglumetad Methionil manufacturer or Pomaglumetad Methionil supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Pomaglumetad Methionil manufacturer or Pomaglumetad Methionil supplier.
A Pomaglumetad Methionil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pomaglumetad Methionil, including repackagers and relabelers. The FDA regulates Pomaglumetad Methionil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pomaglumetad Methionil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Pomaglumetad Methionil supplier is an individual or a company that provides Pomaglumetad Methionil active pharmaceutical ingredient (API) or Pomaglumetad Methionil finished formulations upon request. The Pomaglumetad Methionil suppliers may include Pomaglumetad Methionil API manufacturers, exporters, distributors and traders.
Pomaglumetad Methionil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Pomaglumetad Methionil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Pomaglumetad Methionil GMP manufacturer or Pomaglumetad Methionil GMP API supplier for your needs.
A Pomaglumetad Methionil CoA (Certificate of Analysis) is a formal document that attests to Pomaglumetad Methionil's compliance with Pomaglumetad Methionil specifications and serves as a tool for batch-level quality control.
Pomaglumetad Methionil CoA mostly includes findings from lab analyses of a specific batch. For each Pomaglumetad Methionil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Pomaglumetad Methionil may be tested according to a variety of international standards, such as European Pharmacopoeia (Pomaglumetad Methionil EP), Pomaglumetad Methionil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pomaglumetad Methionil USP).
