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1. 1,4 Diazacyclohexane
2. 1,4 Piperazine
3. 1,4-diazacyclohexane
4. 1,4-piperazine
5. Piperazine
6. Piperazine Diacetate
7. Piperazine Dihydrochloride
8. Piperazine Hexahydrate
9. Piperazine Hydrate
10. Piperazine Hydrobromide
11. Piperazine Hydrochloride
12. Piperazine Phosphate
13. Piperazine Phosphate (1:1)
14. Piperazine Phosphate Anhydrous
15. Piperazine Salt
16. Piperazine Sulfate
17. Piperazine Tartrate
18. Piperazine Tartrate (1:1), (r-(r*,r*))-isomer
19. Piperazine Tartrate, (r-(r*,r*))-isomer
20. Piperazinium Oleate
21. Pripsen
1. Piperazine Hydrochloride
2. 7542-23-6
3. Piperazine, Monohydrochloride
4. Piperazine Hcl
5. 6094-40-2
6. Piperazine;hydrochloride
7. Unii-7n36jha4p6
8. 7n36jha4p6
9. Piperazine Hydrochloride Hydrate
10. Einecs 231-422-5
11. Dtxsid2064739
12. Piperazine, Hydrochloride (1:1)
13. Einecs 228-042-7
14. Purina Liquid Dog Wormer
15. Schembl7690
16. Piperazine Hydrochloride Salt
17. Dtxcid1047782
18. Piperazine Hydrochloric Acid Salt
19. 8006-71-1
20. Db-309178
21. Ns00081249
22. Ns00082816
23. Piperazine Monohydrochloride [green Book]
24. A845331
25. Q27268592
1. Piperazine Hydrochloride
2. Piperazine Dihydrochloride
| Molecular Weight | 122.60 g/mol |
|---|---|
| Molecular Formula | C4H11ClN2 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | g/mol |
| Monoisotopic Mass | g/mol |
| Topological Polar Surface Area | 24.1 |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 26.5 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
Antinematodal Agents
National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)
MEDICATION (VET): HIGHLY EFFECTIVE AS ANTHELMINTIC FOR REMOVAL OF LARGE ROUNDWORMS, ASCARIDS, FROM POULTRY AND SWINE NODULAR WORMS (OESOPHAGOSTOMUM SPP) FROM SWINE, SHEEP AND CATTLE; AND PINWORMS AND SMALL STRONGYLES IN HORSES.
Spencer, E.Y. Guide to the Chemicals Used in Crop Protection. 6th ed. Publication 1093, Research Institute, Agriculture Canada, Ottawa, Canada: Information Canada, 1973., p. 416
CLINICALLY, THE DRUG IS HIGHLY EFFECTIVE AGAINST BOTH ASCARIS LUMBRICOIDES & ENTEROBIUS (OXYURIS) VERMICULARIS. A LARGE NUMBER OF SUBSTITUTED PIPERAZINE DERIVATIVES EXHIBIT ANTIHELMINTIC ACTIVITY, BUT APART FROM DIETHYLCARBAMAZINE NONE HAS FOUND A PLACE IN HUMAN THERAPEUTICS.
Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 966
PIPERAZINE PREPN ARE ALWAYS GIVEN ORALLY. PRIOR FASTING OR SUMPPLEMENTARY TREATMENT WITH CATHARTICS OR ENEMAS IS UNECESSARY.
Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 967
For more Therapeutic Uses (Complete) data for PIPERAZINE HYDROCHLORIDE (9 total), please visit the HSDB record page.
VET: VAPORS & SKIN OR EYE CONTACT WITH CONCN MATERIAL MUST BE AVOIDED.
Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 460
Adequate and well-controlled studies in humans have not been done. Piperazine has been used without apparent adverse effects during pregnancy. In three cases of first trimester exposures to piperazine by pregnant women, no malformations were seen in the fetuses. However, because a study showed that orally administered piperazine undergoes partial conversion to a potentially carcinogenic nitrosamine derivative, it is recommended that piperazine be given to pregnant women only if clearly indicated and then only if alternative drugs are not available.
USP Convention. USPDI-Drug Information for the Health Care Professional. 14th ed. Volume I. Rockville, MD: United States Pharmacopeial Convention, Inc., 1994. (Plus Updates)., p. 2960
PIPERAZINE IS CONTRAINDICATED IN PATIENTS A WITH HISTORY OF EPILEPSY. NEUROTOXIC EFFECTS HAVE OCCURRED IN INDIVIDUALS WITH RENAL DYSFUNCTION BECAUSE URINARY EXCRETION IS MAIN ROUTE OF ELIMINATION OF THE DRUG.
Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 967
There has been a report of cross-reactivity between piperazine and ethylenediamine, a substance used as a stabilizer in topical creams. Piperazine can cause a contact allergy that could be life-threatening in a person who has been sensitized to ethylenediamine either by topical application or by occupational exposure. Although rare, adverse dermatologic problems also may occur due to the cross-sensitivity of these two medications.
USP Convention. USPDI-Drug Information for the Health Care Professional. 14th ed. Volume I. Rockville, MD: United States Pharmacopeial Convention, Inc., 1994. (Plus Updates)., p. 2960
It is contraindicated in patients with renal or hepatic insufficiency or epilepsy. /Piperazine citrate/
American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 1754
2= SLIGHTLY TOXIC; PROBABLE ORAL LETHAL DOSE (HUMAN) 5-15 G/KG, BETWEEN 1 PINT & 1 QT FOR 70 KG PERSON (150 LB).
Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-390
Antinematodal Agents
Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice. (See all compounds classified as Antinematodal Agents.)
NOT ABSORBED THROUGH SKIN IN ACUTE TOXIC AMT.
Spencer, E.Y. Guide to the Chemicals Used in Crop Protection. 6th ed. Publication 1093, Research Institute, Agriculture Canada, Ottawa, Canada: Information Canada, 1973., p. 416
PIPERAZINE IS PARTLY METABOLIZED IN AN UNKNOWN MANNER IN MAN, SINCE ONLY 15% OF 2 G DOSES ARE EXCRETED UNCHANGED. /PIPERAZINE/
WILLIAMS RT; 2ND ED, CHAPMAN AND HALL, 614 (1959)
ANTHELMINTIC ACTION IS BY NARCOTIZING AND IMMOBILIZING INTERNAL PARASITES.
Spencer, E.Y. Guide to the Chemicals Used in Crop Protection. 6th ed. Publication 1093, Research Institute, Agriculture Canada, Ottawa, Canada: Information Canada, 1973., p. 416
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PharmaCompass offers a list of Piperazine Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Piperazine Hydrochloride manufacturer or Piperazine Hydrochloride supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Piperazine Hydrochloride manufacturer or Piperazine Hydrochloride supplier.
PharmaCompass also assists you with knowing the Piperazine Hydrochloride API Price utilized in the formulation of products. Piperazine Hydrochloride API Price is not always fixed or binding as the Piperazine Hydrochloride Price is obtained through a variety of data sources. The Piperazine Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Piperazine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Piperazine Hydrochloride, including repackagers and relabelers. The FDA regulates Piperazine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Piperazine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Piperazine Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Piperazine Hydrochloride supplier is an individual or a company that provides Piperazine Hydrochloride active pharmaceutical ingredient (API) or Piperazine Hydrochloride finished formulations upon request. The Piperazine Hydrochloride suppliers may include Piperazine Hydrochloride API manufacturers, exporters, distributors and traders.
click here to find a list of Piperazine Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Piperazine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Piperazine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Piperazine Hydrochloride GMP manufacturer or Piperazine Hydrochloride GMP API supplier for your needs.
A Piperazine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Piperazine Hydrochloride's compliance with Piperazine Hydrochloride specifications and serves as a tool for batch-level quality control.
Piperazine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Piperazine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Piperazine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Piperazine Hydrochloride EP), Piperazine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Piperazine Hydrochloride USP).
