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Chemistry

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Also known as: Pulsotyl, Veritol, Pressitan, 370-14-9, Paredrinol, Sympropamin
Molecular Formula
C10H15NO
Molecular Weight
165.23  g/mol
InChI Key
SBUQZKJEOOQSBV-UHFFFAOYSA-N
FDA UNII
AY28O44JGD

Pholedrine
1 2D Structure

Pholedrine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[2-(methylamino)propyl]phenol
2.1.2 InChI
InChI=1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3
2.1.3 InChI Key
SBUQZKJEOOQSBV-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(CC1=CC=C(C=C1)O)NC
2.2 Other Identifiers
2.2.1 UNII
AY28O44JGD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-hydroxy-n-methylamphetamine

2. 4-hydroxymethamphetamine

3. P-hydroxymethamphetamine

4. Pholedrin Liquidum

5. Pholedrin-longo-isis

6. Pholedrine Sulfate (1:1)

7. Pholedrine Sulfate (2:1)

8. Pholedrine, Sulfate (1:1), (+-)-isomer

9. Pholedrine, Sulfate (2:1), (+-)-isomer

10. Pulsotyl

11. Veritol

2.3.2 Depositor-Supplied Synonyms

1. Pulsotyl

2. Veritol

3. Pressitan

4. 370-14-9

5. Paredrinol

6. Sympropamin

7. Foledrin

8. Isodrinum

9. Pholetone

10. Stimatone

11. Syncordan

12. Terapinyl

13. Varitol

14. Veritain

15. Epifen

16. 4-[2-(methylamino)propyl]phenol

17. Knoll H75

18. 4-hydroxymethamphetamine

19. Promethin

20. Prometin

21. 4-(2-(methylamino)propyl)phenol

22. P-hydroxymethamphetamine

23. N-methylparedrine

24. Racemic Pholedrine

25. 4-hydroxy-n-methylamphetamine

26. Pholedrinum

27. P-hydroxy-n-methylbenzedrine

28. P-(2-methylaminopropyl)phenol

29. (+/-)-pholedrine

30. Isodrin (sympathomimetic)

31. 1-(p-hydroxyphenyl)-2-methylaminopropane

32. Oh-ma

33. P-hydroxy-n-methylamphetamine

34. P-hydroxy-n,alpha-dimethylphenethylamine

35. Beta-(p-hydroxyphenyl)isopropylmethylamine

36. Phenethylamine, P-hydroxy-n,alpha-dimethyl-

37. Phenol, P-(2-(methylamino)propyl)-

38. Alpha-(p-oxyphenyl)-beta-methyl Aminopropane

39. 1-(p-oxyphenyl)-2-methylaminopropan

40. Knoll-h75

41. Ay28o44jgd

42. Pholedrine (inn)

43. Phenol, 4-(2-(methylamino)propyl)-

44. Phenol, 4-[2-(methylamino)propyl]-

45. P-hydroxy-n,.alpha.-dimethylphenethylamine

46. Pholedrine [inn]

47. .beta.-(p-hydroxyphenyl)isopropylmethylamine

48. .alpha.-(p-hydroxyphenyl)-.beta.-methylaminopropane

49. (+/-)-1-(4-hydroxyphenyl)-n-methyl-2-aminopropane

50. Foledrinio

51. Rac Pholedrine

52. Phenol, P-[2-(methylamino)propyl]-

53. Pholedrinum [inn-latin]

54. Foledrinio [inn-spanish]

55. Pholedrine [inn:ban:dcf]

56. Einecs 206-725-0

57. Unii-ay28o44jgd

58. Pholedrin

59. P-[2-(methylamino)propyl]phenol

60. 1-(p-oxyphenyl)-2-methylaminopropan [german]

61. Alpha-(p-hydroxyphenyl)-beta-methylaminopropane

62. Beta(p-oxy-phenyl)isopropylmethylamin [german]

63. Beta(p-oxy-phenyl)isopropylmethylamin

64. Pholedrine [mi]

65. Pholedrine [who-dd]

66. Schembl119262

67. Chembl2008672

68. Dtxsid70861908

69. P-[(2-methylamino)propyl]phenol

70. Chebi:134798

71. Isodrin (sympathomimetic Compound)

72. P-[2-(methylamino)propyl]-phenol

73. P-hydroxy-n,a-dimethylphenethylamine

74. Akos005216720

75. Akos017390993

76. (+)-4-[2-(methylamino)propyl]phenol

77. (?)-4-[2-(methylamino)propyl]phenol

78. Nci60_042163

79. P-hydroxymethamphetamine, (+/-)-

80. Db-049052

81. Alpha-(p-hydroxyphenyl-beta-methylaminopropane

82. D08370

83. Phenethylamine, P-hydroxy-n,.alpha.-dimethyl-

84. P-hydroxymethamphetamine, 1.0 Mg/ml In Methanol

85. .alpha.-(p-oxyphenyl)-.beta.-methyl Aminopropane

86. Sr-01000944930

87. Q7187065

88. Sr-01000944930-1

89. P-hydroxymethamphetamine, Analytical Standard, For Drug Analysis

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 165.23 g/mol
Molecular Formula C10H15NO
XLogP31.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass165.115364102 g/mol
Monoisotopic Mass165.115364102 g/mol
Topological Polar Surface Area32.3 Ų
Heavy Atom Count12
Formal Charge0
Complexity119
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Central Nervous System Stimulants

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)


Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


4.2 Metabolism/Metabolites

HO-MA is a known human metabolite of p-Methoxymethamphetamine, R-(-)-.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


ABOUT THIS PAGE

Looking for 370-14-9 / Pholedrine API manufacturers, exporters & distributors?

Pholedrine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Pholedrine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Pholedrine manufacturer or Pholedrine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Pholedrine manufacturer or Pholedrine supplier.

PharmaCompass also assists you with knowing the Pholedrine API Price utilized in the formulation of products. Pholedrine API Price is not always fixed or binding as the Pholedrine Price is obtained through a variety of data sources. The Pholedrine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Pholedrine

Synonyms

Pulsotyl, Veritol, Pressitan, 370-14-9, Paredrinol, Sympropamin

Cas Number

370-14-9

Unique Ingredient Identifier (UNII)

AY28O44JGD

Pholedrine Manufacturers

A Pholedrine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pholedrine, including repackagers and relabelers. The FDA regulates Pholedrine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pholedrine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Pholedrine Suppliers

A Pholedrine supplier is an individual or a company that provides Pholedrine active pharmaceutical ingredient (API) or Pholedrine finished formulations upon request. The Pholedrine suppliers may include Pholedrine API manufacturers, exporters, distributors and traders.

Pholedrine GMP

Pholedrine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Pholedrine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pholedrine GMP manufacturer or Pholedrine GMP API supplier for your needs.

Pholedrine CoA

A Pholedrine CoA (Certificate of Analysis) is a formal document that attests to Pholedrine's compliance with Pholedrine specifications and serves as a tool for batch-level quality control.

Pholedrine CoA mostly includes findings from lab analyses of a specific batch. For each Pholedrine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Pholedrine may be tested according to a variety of international standards, such as European Pharmacopoeia (Pholedrine EP), Pholedrine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pholedrine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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