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Chemistry

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Also known as: 125-52-0, Daricon, Ulcociclinina, Spazamin, Syklifen, Cycmin
Molecular Formula
C20H29ClN2O3
Molecular Weight
380.9  g/mol
InChI Key
WXAYTPABEADAAB-UHFFFAOYSA-N
FDA UNII
GWO1432WOU

Oxyphencyclimine
Oxyphencyclimine Hydrochloride is the hydrochloride salt form of oxyphencyclimine, a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities. Oxyphencyclimine binds to and blocks the muscarinic receptor on smooth muscle. This agent has a direct relaxing effect on smooth muscle and therefore prevents spasms in the muscles of the gastrointestinal tract, inhibits gastrointestinal propulsive motility, decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretion.
1 2D Structure

Oxyphencyclimine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate;hydrochloride
2.1.2 InChI
InChI=1S/C20H28N2O3.ClH/c1-22-14-8-13-21-18(22)15-25-19(23)20(24,16-9-4-2-5-10-16)17-11-6-3-7-12-17;/h2,4-5,9-10,17,24H,3,6-8,11-15H2,1H3;1H
2.1.3 InChI Key
WXAYTPABEADAAB-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCCN=C1COC(=O)C(C2CCCCC2)(C3=CC=CC=C3)O.Cl
2.2 Other Identifiers
2.2.1 UNII
GWO1432WOU
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Oxyphencyclimine

2. Oxyphencyclimine Monohydrochloride

3. Oxyphencyclimine, (+-)-isomer

2.3.2 Depositor-Supplied Synonyms

1. 125-52-0

2. Daricon

3. Ulcociclinina

4. Spazamin

5. Syklifen

6. Cycmin

7. Dominil

8. Enterex

9. Gastrix

10. Oximin

11. Setrol

12. Manir

13. Vio-thene

14. Oxyphencyclimine Hcl

15. W-t Anticholinergic

16. Oxyphencyclimine (hydrochloride)

17. Oxyphencyclimine Hydrochloride [jan]

18. Nsc-528449

19. S 1-1236

20. Gwo1432wou

21. Mls000069551

22. (1-methyl-5,6-dihydro-4h-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate;hydrochloride

23. 21609-10-9

24. Ncgc00095084-01

25. Vagogastrin

26. Smr000058818

27. Dsstox_cid_25909

28. Dsstox_rid_81220

29. Dsstox_gsid_45909

30. (1-methyl-5,6-dihydro-4h-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate Hydrochloride

31. Vistrax

32. Oxyphencyclimine Hydrochloride (jan)

33. Cas-125-52-0

34. Einecs 204-742-8

35. Unii-gwo1432wou

36. Nsc 528449

37. Daricol

38. Component Of Enarax

39. Daricon (tn)

40. Component Of Vistrax

41. Oxyphencyclimine Hydrochloride [usp:jan]

42. Oxiphencyclimine Chloride

43. Opera_id_1394

44. Oxyphencycliminehydrochloride

45. 1-methyl-1,4,5,6-tetrahydro-2-pyrimidylmethyl-alpha-cyclohexyl-phenylglycolate Hydrochloride

46. (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Alpha-phenylcyclohexaneglycolate Monohydrochloride

47. Mls001074201

48. Schembl663333

49. Spectrum1503932

50. Regid_for_cid_66061

51. Chebi:7869

52. Chembl1200891

53. Dtxsid6045909

54. Hms1922m10

55. Pharmakon1600-01503932

56. Bcp19587

57. Hy-b0954

58. Tox21_111416

59. Ccg-39378

60. Nsc528449

61. Nsc758648

62. Tox21_111416_1

63. Nsc-758648

64. Ncgc00018210-05

65. Ncgc00095084-02

66. Ncgc00095084-03

67. Ac-15984

68. Benzeneacetic Acid, .alpha.-cyclohexyl-.alpha.-hydroxy-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester, Monohydrochloride

69. Benzeneacetic Acid, Alpha-cyclohexyl-alpha-hydroxy-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester Monohydrochloride

70. Cyclohexaneglycolic Acid, Alpha-phenyl-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester, Monohydrochloride

71. Oxyphencyclimine Hydrochloride [mi]

72. Ft-0707726

73. Oxyphencyclimine Hydrochloride [vandf]

74. Oxyphencyclimine Hydrochloride [mart.]

75. D01006

76. Oxyphencyclimine Hydrochloride [who-dd]

77. Oxyphencyclimine Hydrochloride [orange Book]

78. Q-201529

79. Q27279322

80. (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl .alpha.-phenylcyclohexaneglycolate Monohydrochloride

81. Benzeneacetic Acid, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester, Monohydrochloride

82. Benzeneacetic Acid, A-cyclohexyl-a-hydroxy-,(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester, Hydrochloride (1:1)

83. Benzeneacetic Acid,a-cyclohexyl-a-hydroxy-,(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester,hydrochloride(1:1)

84. Cyclohexaneglycolic Acid, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester Monohydrochloride

85. Cyclohexaneglycolic Acid, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl Ester, Monohydrochloride

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 380.9 g/mol
Molecular Formula C20H29ClN2O3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass380.1866705 g/mol
Monoisotopic Mass380.1866705 g/mol
Topological Polar Surface Area62.1 Ų
Heavy Atom Count26
Formal Charge0
Complexity481
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

ABOUT THIS PAGE

Looking for 125-52-0 / Oxyphencyclimine API manufacturers, exporters & distributors?

Oxyphencyclimine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Oxyphencyclimine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Oxyphencyclimine manufacturer or Oxyphencyclimine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Oxyphencyclimine manufacturer or Oxyphencyclimine supplier.

PharmaCompass also assists you with knowing the Oxyphencyclimine API Price utilized in the formulation of products. Oxyphencyclimine API Price is not always fixed or binding as the Oxyphencyclimine Price is obtained through a variety of data sources. The Oxyphencyclimine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Oxyphencyclimine

Synonyms

125-52-0, Daricon, Ulcociclinina, Spazamin, Syklifen, Cycmin

Cas Number

125-52-0

Unique Ingredient Identifier (UNII)

GWO1432WOU

About Oxyphencyclimine

Oxyphencyclimine Hydrochloride is the hydrochloride salt form of oxyphencyclimine, a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities. Oxyphencyclimine binds to and blocks the muscarinic receptor on smooth muscle. This agent has a direct relaxing effect on smooth muscle and therefore prevents spasms in the muscles of the gastrointestinal tract, inhibits gastrointestinal propulsive motility, decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretion.

Oxyphencyclimine Manufacturers

A Oxyphencyclimine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxyphencyclimine, including repackagers and relabelers. The FDA regulates Oxyphencyclimine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxyphencyclimine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Oxyphencyclimine Suppliers

A Oxyphencyclimine supplier is an individual or a company that provides Oxyphencyclimine active pharmaceutical ingredient (API) or Oxyphencyclimine finished formulations upon request. The Oxyphencyclimine suppliers may include Oxyphencyclimine API manufacturers, exporters, distributors and traders.

Oxyphencyclimine GMP

Oxyphencyclimine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oxyphencyclimine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxyphencyclimine GMP manufacturer or Oxyphencyclimine GMP API supplier for your needs.

Oxyphencyclimine CoA

A Oxyphencyclimine CoA (Certificate of Analysis) is a formal document that attests to Oxyphencyclimine's compliance with Oxyphencyclimine specifications and serves as a tool for batch-level quality control.

Oxyphencyclimine CoA mostly includes findings from lab analyses of a specific batch. For each Oxyphencyclimine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oxyphencyclimine may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxyphencyclimine EP), Oxyphencyclimine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxyphencyclimine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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