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1. Methylphenylisoxazolyl Penicillin
2. Oxacillin Sodium
3. Oxacillin, Monosodium Salt, Anhydrous
4. Oxacillin, Monosodium Salt, Monohydrate
5. Oxacillin, Sodium
6. Oxazocilline
7. Penicillin, Methylphenylisoxazolyl
8. Prostaphlin
9. Sodium Oxacillin
10. Sodium, Oxacillin
1. Oxazocillin
2. 66-79-5
3. Oxazocilline
4. Mpi-penicillin
5. Oxacilina
6. Bactocill
7. Prostaphlin
8. Oxacillin Sodium
9. 5-methyl-3-phenyl-4-isoxazolyl-penicillin
10. Oxacillin (inn)
11. Chebi:7809
12. (2s,5r,6r)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
13. (5-methyl-3-phenyl-4-isoxazolyl)penicillin
14. Penicillin, (5-methyl-3-phenyl-4-isoxazolyl)-
15. 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanic Acid
16. Uh95vd7v76
17. (2s,5r,6r)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
18. Ossacillina
19. Oxacilline
20. Oxacillinum
21. Prostaphlyn
22. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]amino]-7-oxo-, (2s,5r,6r)-
23. Ossacillina [dcit]
24. Oxacillin [inn]
25. Mpi-pc
26. Oxacillin [inn:ban]
27. Oxacilina [inn-spanish]
28. Oxacilline [inn-french]
29. Oxacillinum [inn-latin]
30. 1173-88-2
31. Oxacilina (tn)
32. Einecs 200-635-5
33. Unii-uh95vd7v76
34. Oxacillin,(s)
35. (2s,5r,6r)-3,3-dimethyl-6-[(5-methyl-3-phenyl-isoxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
36. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-, (2s-(2alpha,5alpha,6beta))-
37. Oxacillin [mi]
38. Oxacillin [vandf]
39. Chembl819
40. Epitope Id:181859
41. Oxacillin [mart.]
42. Oxacillin [who-dd]
43. Schembl3817
44. Dtxsid8023397
45. Gtpl10943
46. Hy-b0925a
47. Phenylisoxazole-4-carboxamido)-7-
48. Zinc3875439
49. Bdbm50350483
50. Db00713
51. 2,2-dimethyl-6beta-(5-methyl-3-phenyl-1,2-oxazole-4-carboxamido)penam-3alpha-carboxylic Acid
52. (2s,5r,6r)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
53. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamide)-7-oxo-
54. 5-methyl-3-phenyl-4-isooxazolylpenicillin
55. Oxo-4-thia-1-azabicyclo[3.2.0]heptane-
56. Cs-0013715
57. C07334
58. D08307
59. (2s,5r,6r)-3,3-dimethyl-6-(5-methyl-3-
60. Q418725
61. Brd-k96786677-236-01-6
62. Brd-k96786677-236-02-4
63. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-,(2s,5r,6r)-
64. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-6-(((5-methyl-3-phenyl-4-isoxazolyl)carbonyl)amino)-7-oxo-, (2s-(2.alpha.,5.alpha.,6.beta.))-
| Molecular Weight | 401.4 g/mol |
|---|---|
| Molecular Formula | C19H19N3O5S |
| XLogP3 | 2.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 401.10454189 g/mol |
| Monoisotopic Mass | 401.10454189 g/mol |
| Topological Polar Surface Area | 138 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 681 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
| 1 of 2 | |
|---|---|
| Drug Name | Oxacillin sodium |
| Drug Label | Oxacillin for Injection, USP is a semisynthetic penicillin antibiotic derived from the penicillin nucleus, 6-amino-penicillanic acid. It is resistant to inactivation by the enzyme penicillinase (beta-lactamase). It is the sodium salt in parenteral do... |
| Active Ingredient | Oxacillin sodium |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | eq 2gm base/vial; eq 10gm base/vial; eq 1gm base/vial |
| Market Status | Prescription |
| Company | Aurobindo Pharma; Sandoz; Sagent Pharms; Agila Speclts |
| 2 of 2 | |
|---|---|
| Drug Name | Oxacillin sodium |
| Drug Label | Oxacillin for Injection, USP is a semisynthetic penicillin antibiotic derived from the penicillin nucleus, 6-amino-penicillanic acid. It is resistant to inactivation by the enzyme penicillinase (beta-lactamase). It is the sodium salt in parenteral do... |
| Active Ingredient | Oxacillin sodium |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | eq 2gm base/vial; eq 10gm base/vial; eq 1gm base/vial |
| Market Status | Prescription |
| Company | Aurobindo Pharma; Sandoz; Sagent Pharms; Agila Speclts |
Used in the treatment of resistant staphylococci infections.
Oxacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Oxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Oxacillin results from the inhibition of cell wall synthesis and is mediated through Oxacillin binding to penicillin binding proteins (PBPs). Oxacillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Anti-Bacterial Agents
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
J - Antiinfectives for systemic use
J01 - Antibacterials for systemic use
J01C - Beta-lactam antibacterials, penicillins
J01CF - Beta-lactamase resistant penicillins
J01CF04 - Oxacillin
Route of Elimination
Oxacillin Sodium is rapidly excreted as unchanged drug in the urine by glomerular filtration and active tubular secretion.
20 to 30 minutes
By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Oxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Oxacillin interferes with an autolysin inhibitor.
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PharmaCompass offers a list of Oxacillin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Oxacillin manufacturer or Oxacillin supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Oxacillin manufacturer or Oxacillin supplier.
PharmaCompass also assists you with knowing the Oxacillin API Price utilized in the formulation of products. Oxacillin API Price is not always fixed or binding as the Oxacillin Price is obtained through a variety of data sources. The Oxacillin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Oxacil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oxacil, including repackagers and relabelers. The FDA regulates Oxacil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oxacil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Oxacil supplier is an individual or a company that provides Oxacil active pharmaceutical ingredient (API) or Oxacil finished formulations upon request. The Oxacil suppliers may include Oxacil API manufacturers, exporters, distributors and traders.
click here to find a list of Oxacil suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Oxacil DMF (Drug Master File) is a document detailing the whole manufacturing process of Oxacil active pharmaceutical ingredient (API) in detail. Different forms of Oxacil DMFs exist exist since differing nations have different regulations, such as Oxacil USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Oxacil DMF submitted to regulatory agencies in the US is known as a USDMF. Oxacil USDMF includes data on Oxacil's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Oxacil USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Oxacil suppliers with USDMF on PharmaCompass.
A Oxacil written confirmation (Oxacil WC) is an official document issued by a regulatory agency to a Oxacil manufacturer, verifying that the manufacturing facility of a Oxacil active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Oxacil APIs or Oxacil finished pharmaceutical products to another nation, regulatory agencies frequently require a Oxacil WC (written confirmation) as part of the regulatory process.
click here to find a list of Oxacil suppliers with Written Confirmation (WC) on PharmaCompass.
Oxacil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Oxacil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oxacil GMP manufacturer or Oxacil GMP API supplier for your needs.
A Oxacil CoA (Certificate of Analysis) is a formal document that attests to Oxacil's compliance with Oxacil specifications and serves as a tool for batch-level quality control.
Oxacil CoA mostly includes findings from lab analyses of a specific batch. For each Oxacil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Oxacil may be tested according to a variety of international standards, such as European Pharmacopoeia (Oxacil EP), Oxacil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oxacil USP).
