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Orgotein

Orgotein

Synopsis, Chemistry

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Also known as: Orgotein, bovine, Orgotein [inn], Orgotein [usan], Orgotein [mart.], Orgotein [who-dd], Orgotein [green book]

Molecular Formula

Cu₄Zn₄+₁₆

Molecular Weight

515.7 g/mol

InChI Key

TUGDLVFMIQZYPA-UHFFFAOYSA-N

1 2D Structure

Orgotein

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

tetracopper;tetrazinc

2.1.2 InChI

InChI=1S/4Cu.4Zn/q8*+2

2.1.3 InChI Key

TUGDLVFMIQZYPA-UHFFFAOYSA-N

2.1.4 Canonical SMILES

[Cu+2].[Cu+2].[Cu+2].[Cu+2].[Zn+2].[Zn+2].[Zn+2].[Zn+2]

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Bovine Copper-zinc Superoxide Dismutase

2. Ontose

3. Ontosein

4. Ormetein

5. Palosein

6. Peroxinorm

7. Superoxide Dismutase (bovine)

2.2.2 Depositor-Supplied Synonyms

1. Orgotein, Bovine

2. Orgotein [inn]

3. Orgotein [usan]

4. Orgotein [mart.]

5. Orgotein [who-dd]

6. Orgotein [green Book]

7. Ontosein

8. Ormetein

9. Palosein

10. Superoxide Dismutase (bovine)

11. Copper-zinc Superoxide Dismutase

12. Superoxide Dismutase, Bovine (cu-zn)

13. Orgotein [usan:inn]

14. Unii-pke82w49v1

15. Pke82w49v1

16. Bovine Copper-zinc Superoxide Dismutase

17. 1569268-91-2

2.3 Create Date

2014-03-02

3 Chemical and Physical Properties

Molecular Formula	Cu₄Zn₄+₁₆
Molecular Weight	515.7 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	0
Exact Mass	515.42574 g/mol
Monoisotopic Mass	507.43496 g/mol
Topological Polar Surface Area	0 Å²
Heavy Atom Count	8
Formal Charge	16
Complexity	0
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	8

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

4.2 ATC Code

M - Musculo-skeletal system

M01 - Antiinflammatory and antirheumatic products

M01A - Antiinflammatory and antirheumatic products, non-steroids

M01AX - Other antiinflammatory and antirheumatic agents, non-steroids

M01AX14 - Orgotein