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1. 11-(3-(dimethylamino)propylidene)-6,11-dihydrodibenz(b,e)oxepin-2-acetic Acid
2. 4679, Kw
3. Hydrochloride, Olopatadine
4. Kw 4679
5. Kw 4943a
6. Kw-4679
7. Kw-4943a
8. Kw4943a
9. Olopatadine
10. Patanol
1. 140462-76-6
2. Olopatadine Hcl
3. Allelock
4. Pataday
5. Patanase
6. Alo4943a
7. Pazeo
8. Kw4679
9. Kw-4679
10. Olopatadine (hydrochloride)
11. Alo-4943a
12. (z)-2-(11-(3-(dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic Acid Hydrochloride
13. Olopatadine (as Hydrochloride)
14. 2xg66w44kf
15. Dsstox_cid_26486
16. Dsstox_rid_81657
17. Dsstox_gsid_46486
18. Dibenz(b,e)oxepin-2-acetic Acid, 11-(3-(dimethylamino)propylidene)-6,11-dihydro-, Hydrochloride, (z)-
19. Olopine
20. Patadine
21. Olopax
22. Chembl1719
23. Kw 4679
24. Cas-140462-76-6
25. Opatanol (tn)
26. Unii-2xg66w44kf
27. Sr-01000763388
28. Alo 4943a
29. Olopatadine Hydrochloride [usan]
30. Allelock (tn)
31. Patanol (tn)
32. De 114
33. Mfcd00875716
34. Olopatadine Hydrochloride [usan:usp]
35. Olopatadine Hydrochlorde
36. O-ppds
37. Ncgc00164623-01
38. Schembl23213
39. Mls001401465
40. Dtxsid0046486
41. Chebi:31933
42. Hy-b0426a
43. Olopatadine Hydrochloride- Bio-x
44. Al4943a
45. Alo4943a;kw4679
46. 2-[(11z)-11-[3-(dimethylamino)propylidene]-6h-benzo[c][1]benzoxepin-2-yl]acetic Acid;hydrochloride
47. Dibenz[b,e]oxepin-2-acetic Acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, Hydrochloride (1:1), (11z)-
48. Ex-a1347
49. Olopatadine Hydrochloride (opatanol)
50. Tox21_112242
51. S2494
52. Olopatadine Hydrochloride [mi]
53. Akos015895232
54. Akos025149118
55. Olopatadine Hydrochloride (jp17/usp)
56. Tox21_112242_1
57. Bcp9001022
58. Ccg-101141
59. H06o056
60. Ks-1228
61. Nc00391
62. Olopatadine Hydrochloride [jan]
63. Ncgc00263532-01
64. Olopatadine Hydrochloride [mart.]
65. Olopatadine Hydrochloride [vandf]
66. 11-((z)-3-(dimethylamino)propylidene)-6,11-dihydrodibenz(b,e)oxepin-2-acetic Acid Hydrochloride
67. 11-((z)-3-(dimethylamino)propylidene)-6,11-dihydrodibenz(b,e)oxepin-2-acetic Acid, Hydrochloride
68. Bo164171
69. Dibenz(b,e)oxepin-2-acetic Acid, 11-(3-dimethylamino)propylidene)-6,11-dihydro-, Hydrochloride, (z)-
70. Olopatadine Hydrochloride [usp-rs]
71. Olopatadine Hydrochloride [who-dd]
72. Smr000469220
73. Olopatadine Hydrochloride, >=98% (hplc)
74. Olopatadine Hydrochloride [ema Epar]
75. O0361
76. C72607
77. D01192
78. Olopatadine Hydrochloride [orange Book]
79. Olopatadine Hydrochloride [usp Monograph]
80. A807652
81. Ryaltris Component Olopatadine Hydrochloride
82. Q-201511
83. Sr-01000763388-4
84. Olopatadine Hydrochloride Component Of Ryaltris
85. Q27255766
86. Olopatadine Hydrochloride, United States Pharmacopeia (usp) Reference Standard
87. (z)-11-[3-(dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic Acid Hydrochloride
88. (z)-2-(11-(3-(dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)aceticacidhydrochloride
| Molecular Weight | 373.9 g/mol |
|---|---|
| Molecular Formula | C21H24ClNO3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 373.1444713 g/mol |
| Monoisotopic Mass | 373.1444713 g/mol |
| Topological Polar Surface Area | 49.8 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 488 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
| 1 of 8 | |
|---|---|
| Drug Name | Olopatadine hydrochloride |
| Drug Label | Olopatadine Hydrochloride Nasal Solution (Nasal Spray), 665 micrograms (mcg) is a metered-spray solution for intranasal administration. Olopatadine hydrochloride, the active component of Olopatadine Hydrochloride Nasal Solution (Nasal Spray), is a wh... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Solution/drops; Spray, metered; Solution |
| Route | Ophthalmic; Nasal; ophthalmic |
| Strength | 0.665mg/spray; 0.2% base; 0.1%; eq 0.1% base; 0.2% |
| Market Status | Tentative Approval; Prescription |
| Company | Wockhardt; Apotex; Sandoz; Watson Labs; Barr |
| 2 of 8 | |
|---|---|
| Drug Name | Pataday |
| Drug Label | PATADAY (olopatadine hydrochloride ophthalmic solution) 0.2% is a sterile ophthalmic solution containing olopatadine for topical administration to the eyes.Olopatadine hydrochloride is a white, crystalline, water-soluble powder with a molecular we... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | eq 0.2% base |
| Market Status | Prescription |
| Company | Alcon Pharms |
| 3 of 8 | |
|---|---|
| Drug Name | Patanase |
| PubMed Health | Olopatadine (Into the nose) |
| Drug Classes | Nasal Agent |
| Drug Label | PATANASE (olopatadine hydrochloride) Nasal Spray, 665 micrograms (mcg) is a metered-spray solution for intranasal administration. Olopatadine hydrochloride, the active component of PATANASE Nasal Spray, is a white, water-soluble crystalline powder. T... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Spray, metered |
| Route | Nasal |
| Strength | 0.665mg/spray |
| Market Status | Prescription |
| Company | Alcon Pharms |
| 4 of 8 | |
|---|---|
| Drug Name | Patanol |
| PubMed Health | Olopatadine |
| Drug Classes | Nasal Agent, Ophthalmologic Agent |
| Drug Label | PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% is a sterile ophthalmic solution containing olopatadine, a relatively selective H1-receptor antagonist and inhibitor of histamine release from the mast cell for topical administration to... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | eq 0.1% base |
| Market Status | Prescription |
| Company | Alcon |
| 5 of 8 | |
|---|---|
| Drug Name | Olopatadine hydrochloride |
| Drug Label | Olopatadine Hydrochloride Nasal Solution (Nasal Spray), 665 micrograms (mcg) is a metered-spray solution for intranasal administration. Olopatadine hydrochloride, the active component of Olopatadine Hydrochloride Nasal Solution (Nasal Spray), is a wh... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Solution/drops; Spray, metered; Solution |
| Route | Ophthalmic; Nasal; ophthalmic |
| Strength | 0.665mg/spray; 0.2% base; 0.1%; eq 0.1% base; 0.2% |
| Market Status | Tentative Approval; Prescription |
| Company | Wockhardt; Apotex; Sandoz; Watson Labs; Barr |
| 6 of 8 | |
|---|---|
| Drug Name | Pataday |
| Drug Label | PATADAY (olopatadine hydrochloride ophthalmic solution) 0.2% is a sterile ophthalmic solution containing olopatadine for topical administration to the eyes.Olopatadine hydrochloride is a white, crystalline, water-soluble powder with a molecular we... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | eq 0.2% base |
| Market Status | Prescription |
| Company | Alcon Pharms |
| 7 of 8 | |
|---|---|
| Drug Name | Patanase |
| PubMed Health | Olopatadine (Into the nose) |
| Drug Classes | Nasal Agent |
| Drug Label | PATANASE (olopatadine hydrochloride) Nasal Spray, 665 micrograms (mcg) is a metered-spray solution for intranasal administration. Olopatadine hydrochloride, the active component of PATANASE Nasal Spray, is a white, water-soluble crystalline powder. T... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Spray, metered |
| Route | Nasal |
| Strength | 0.665mg/spray |
| Market Status | Prescription |
| Company | Alcon Pharms |
| 8 of 8 | |
|---|---|
| Drug Name | Patanol |
| PubMed Health | Olopatadine |
| Drug Classes | Nasal Agent, Ophthalmologic Agent |
| Drug Label | PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% is a sterile ophthalmic solution containing olopatadine, a relatively selective H1-receptor antagonist and inhibitor of histamine release from the mast cell for topical administration to... |
| Active Ingredient | Olopatadine hydrochloride |
| Dosage Form | Solution/drops |
| Route | Ophthalmic |
| Strength | eq 0.1% base |
| Market Status | Prescription |
| Company | Alcon |
Treatment of ocular signs and symptoms of seasonal allergic conjunctivitis.
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
Histamine H1 Antagonists, Non-Sedating
A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment. (See all compounds classified as Histamine H1 Antagonists, Non-Sedating.)
Anti-Allergic Agents
Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)
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