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Chemistry

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Also known as: 32619-42-4, Oleoeuropein, Oleoeuropeine, 2-(3,4-dihydroxyphenyl)ethyl (2s-(2alpha,3e,4beta))-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2h-pyran-4-acetate, Methyl (4s,5e,6s)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4h-pyran-3-carboxylate, 2o4553545l
Molecular Formula
C25H32O13
Molecular Weight
540.5  g/mol
InChI Key
RFWGABANNQMHMZ-ZCHJGGQASA-N
FDA UNII
2O4553545L

Oleuropein
oleuropein is a natural product found in Jasminum officinale, Olea capensis, and other organisms with data available.
1 2D Structure

Oleuropein

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate
2.1.2 InChI
InChI=1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
2.1.3 InChI Key
RFWGABANNQMHMZ-ZCHJGGQASA-N
2.1.4 Canonical SMILES
CC=C1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC(=C(C=C3)O)O
2.1.5 Isomeric SMILES
C/C=C/1\[C@@H](C(=CO[C@H]1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC(=C(C=C3)O)O
2.2 Other Identifiers
2.2.1 UNII
2O4553545L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(3,4-dihydroxyphenyl)ethyl (2s-(2alpha,3e,4beta))-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2h-pyran-4-acetate

2. Oleoeuropein

3. Oleoeuropeine

2.3.2 Depositor-Supplied Synonyms

1. 32619-42-4

2. Oleoeuropein

3. Oleoeuropeine

4. 2-(3,4-dihydroxyphenyl)ethyl (2s-(2alpha,3e,4beta))-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2h-pyran-4-acetate

5. Methyl (4s,5e,6s)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4h-pyran-3-carboxylate

6. 2o4553545l

7. 2h-pyran-4-acetic Acid, 3-ethylidene-2-(.beta.-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl Ester, (2s,3e,4s)-

8. Methyl (2s,3e,4s)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2h-pyran-5-carboxylate

9. Einecs 251-129-6

10. Oleuroperin

11. Unii-2o4553545l

12. Oleuropein [mi]

13. Oleuropein [inci]

14. Oleuropein [vandf]

15. Oleuropein, >=98.0%

16. Oleuropein [usp-rs]

17. Oleuropein [who-dd]

18. Oleuropein, Analytical Standard

19. Chebi:7747

20. Megxp0_000369

21. Schembl4306969

22. Chembl1911053

23. Oleuropein, >=80% (hplc)

24. Acon1_000443

25. Gtpl11027

26. Dtxsid60905103

27. Hy-n0292

28. Zinc4098348

29. Mfcd16879008

30. Akos015900702

31. Ccg-269961

32. Ncgc00169074-01

33. Ncgc00169074-02

34. As-56230

35. Cs-0008800

36. O0420

37. S7867

38. A12095

39. Q402625

40. Oleuropein, Primary Pharmaceutical Reference Standard

41. Brd-k08037284-001-01-4

42. Oleuropein, European Pharmacopoeia (ep) Reference Standard

43. Oleuropein, United States Pharmacopeia (usp) Reference Standard

44. (4s)-5,6-dihydro-5-ethylidene-3-(methoxycarbonyl)-6alpha-(beta-d-glucopyranosyloxy)-4h-pyran-4beta-acetic Acid 2-(3,4-dihydroxyphenyl)ethyl Ester

45. [2s-(2alpha,3e,4beta)]-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2h-pyran-4-acetic Acid 2-(3,4-dihydroxyphenyl)ethyl Ester

46. 2h-pyran-4-acetic Acid, 3-ethylidene-2-(.beta.-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl Ester, (2s-(2.alpha.,3e,4.beta.))-

47. 2h-pyran-4-acetic Acid, 5-carboxy-3-ethylidene-2-(.beta.-d-glucosyloxy)-3,4-dihydro-, 3,4-dihydroxyphenethyl 5-methyl Ester

48. Methyl (2s,3e,4s)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-2h-pyran-5-carboxylate

49. Methyl (2s,4s,e)-4-(2-(3,4-dihydroxyphenethoxy)-2-oxoethyl)-3-ethylidene-2-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)-3,4-dihydro-2h-pyran-5-carboxylate

50. Methyl (4s,5e,6s)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxo-ethyl]-5-ethylidene-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4h-pyran-3-carboxylate

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 540.5 g/mol
Molecular Formula C25H32O13
XLogP3-0.4
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count13
Rotatable Bond Count11
Exact Mass540.18429107 g/mol
Monoisotopic Mass540.18429107 g/mol
Topological Polar Surface Area202 Ų
Heavy Atom Count38
Formal Charge0
Complexity873
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)


Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)


REF. STANDARDS & IMPURITIES

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PharmaCompass offers a list of Oleuropein API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Oleuropein manufacturer or Oleuropein supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Oleuropein manufacturer or Oleuropein supplier.

PharmaCompass also assists you with knowing the Oleuropein API Price utilized in the formulation of products. Oleuropein API Price is not always fixed or binding as the Oleuropein Price is obtained through a variety of data sources. The Oleuropein Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Oleuropein

Synonyms

32619-42-4, Oleoeuropein, Oleoeuropeine, 2-(3,4-dihydroxyphenyl)ethyl (2s-(2alpha,3e,4beta))-3-ethylidene-2-(beta-d-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2h-pyran-4-acetate, Methyl (4s,5e,6s)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4h-pyran-3-carboxylate, 2o4553545l

Cas Number

32619-42-4

Unique Ingredient Identifier (UNII)

2O4553545L

About Oleuropein

oleuropein is a natural product found in Jasminum officinale, Olea capensis, and other organisms with data available.

Oleuropein Manufacturers

A Oleuropein manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Oleuropein, including repackagers and relabelers. The FDA regulates Oleuropein manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Oleuropein API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Oleuropein Suppliers

A Oleuropein supplier is an individual or a company that provides Oleuropein active pharmaceutical ingredient (API) or Oleuropein finished formulations upon request. The Oleuropein suppliers may include Oleuropein API manufacturers, exporters, distributors and traders.

Oleuropein GMP

Oleuropein Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Oleuropein GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Oleuropein GMP manufacturer or Oleuropein GMP API supplier for your needs.

Oleuropein CoA

A Oleuropein CoA (Certificate of Analysis) is a formal document that attests to Oleuropein's compliance with Oleuropein specifications and serves as a tool for batch-level quality control.

Oleuropein CoA mostly includes findings from lab analyses of a specific batch. For each Oleuropein CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Oleuropein may be tested according to a variety of international standards, such as European Pharmacopoeia (Oleuropein EP), Oleuropein JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Oleuropein USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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