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Chemistry

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Also known as: 1415119-52-6, Ovr52k7bdw, Odalasvir (ach-3102), Ach-3102, Ach-0143102, Carbamic acid, n,n'-(tricyclo(8.2.2.24,7)hexadeca-4,6,10,12,13,15-hexaene-5,11-diylbis(1h-benzimidazole-6,2-diyl((2s,3as,7as)-octahydro-1h-indole-2,1-diyl)((1s)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl)))bis-, c,c'-dimethyl ester
Molecular Formula
C60H72N8O6
Molecular Weight
1001.3  g/mol
InChI Key
LSYBRGMTRKJATA-IVEWBXRVSA-N
FDA UNII
OVR52K7BDW

Odalasvir
Odalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection.
1 2D Structure

Odalasvir

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl N-[(2S)-1-[(2S,3aS,7aS)-2-[6-[11-[2-[(2S,3aS,7aS)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-2-yl]-3H-benzimidazol-5-yl]-5-tricyclo[8.2.2.24,7]hexadeca-1(12),4,6,10,13,15-hexaenyl]-1H-benzimidazol-2-yl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
2.1.2 InChI
InChI=1S/C60H72N8O6/c1-33(2)53(65-59(71)73-5)57(69)67-49-13-9-7-11-41(49)31-51(67)55-61-45-25-23-39(29-47(45)63-55)43-27-35-15-19-37(43)21-17-36-16-20-38(22-18-35)44(28-36)40-24-26-46-48(30-40)64-56(62-46)52-32-42-12-8-10-14-50(42)68(52)58(70)54(34(3)4)66-60(72)74-6/h15-16,19-20,23-30,33-34,41-42,49-54H,7-14,17-18,21-22,31-32H2,1-6H3,(H,61,63)(H,62,64)(H,65,71)(H,66,72)/t41-,42-,49-,50-,51-,52-,53-,54-/m0/s1
2.1.3 InChI Key
LSYBRGMTRKJATA-IVEWBXRVSA-N
2.1.4 Canonical SMILES
CC(C)C(C(=O)N1C2CCCCC2CC1C3=NC4=C(N3)C=C(C=C4)C5=C6CCC7=CC(=C(CCC(=C5)C=C6)C=C7)C8=CC9=C(C=C8)N=C(N9)C1CC2CCCCC2N1C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC
2.1.5 Isomeric SMILES
CC(C)[C@@H](C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C3=NC4=C(N3)C=C(C=C4)C5=C6CCC7=CC(=C(CCC(=C5)C=C6)C=C7)C8=CC9=C(C=C8)N=C(N9)[C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
2.2 Other Identifiers
2.2.1 UNII
OVR52K7BDW
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ach-3102

2.3.2 Depositor-Supplied Synonyms

1. 1415119-52-6

2. Ovr52k7bdw

3. Odalasvir (ach-3102)

4. Ach-3102

5. Ach-0143102

6. Carbamic Acid, N,n'-(tricyclo(8.2.2.24,7)hexadeca-4,6,10,12,13,15-hexaene-5,11-diylbis(1h-benzimidazole-6,2-diyl((2s,3as,7as)-octahydro-1h-indole-2,1-diyl)((1s)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl)))bis-, C,c'-dimethyl Ester

7. Dimethyl N,n'-(1,4(1,4)-dibenzenacyclohexaphane-12,42-diylbis(1hbenzimidazole-5,2-diyl((2s,3as,7as)-octahydro-1h-indole-2,1-diyl)((2s)-3-methyl-1-oxobutan-1,2-diyl)))biscarbamate

8. Dimethyl ((2s,2's)-((2s,2's,3as,3a's,7as,7a's)-(1,4(1,4)-dibenzenacyclohexaphane-12,43-diylbis(1h-benzo[d]imidazole-6,2-diyl))bis(octahydro-1h-indole-2,1-diyl))bis(3-methyl-1-oxobutane-1,2-diyl))dicarbamate

9. Methyl N-[(2s)-1-[(2s,3as,7as)-2-[6-[11-[2-[(2s,3as,7as)-1-[(2s)-2-(methoxycarbonylamino)-3-methylbutanoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-2-yl]-3h-benzimidazol-5-yl]-5-tricyclo[8.2.2.24,7]hexadeca-1(12),4,6,10,13,15-hexaenyl]-1h-benzimidazol-2-yl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

10. Odalasvir [usan:inn]

11. Unii-ovr52k7bdw

12. Odalasvir [inn]

13. Odalasvir [usan]

14. Odalasvir [who-dd]

15. Chembl3544977

16. Schembl14122808

17. Schembl18685009

18. Schembl19236067

19. Dtxsid401032258

20. Db13041

21. Q4650666

2.4 Create Date
2013-06-10
3 Chemical and Physical Properties
Molecular Weight 1001.3 g/mol
Molecular Formula C60H72N8O6
XLogP311.5
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count12
Exact Mass1000.55748205 g/mol
Monoisotopic Mass1000.55748205 g/mol
Topological Polar Surface Area175 Ų
Heavy Atom Count74
Formal Charge0
Complexity1840
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


ABOUT THIS PAGE

Looking for 1415119-52-6 / Odalasvir API manufacturers, exporters & distributors?

Odalasvir manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Odalasvir API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Odalasvir manufacturer or Odalasvir supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Odalasvir manufacturer or Odalasvir supplier.

PharmaCompass also assists you with knowing the Odalasvir API Price utilized in the formulation of products. Odalasvir API Price is not always fixed or binding as the Odalasvir Price is obtained through a variety of data sources. The Odalasvir Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Odalasvir

Synonyms

1415119-52-6, Ovr52k7bdw, Odalasvir (ach-3102), Ach-3102, Ach-0143102, Carbamic acid, n,n'-(tricyclo(8.2.2.24,7)hexadeca-4,6,10,12,13,15-hexaene-5,11-diylbis(1h-benzimidazole-6,2-diyl((2s,3as,7as)-octahydro-1h-indole-2,1-diyl)((1s)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl)))bis-, c,c'-dimethyl ester

Cas Number

1415119-52-6

Unique Ingredient Identifier (UNII)

OVR52K7BDW

About Odalasvir

Odalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection.

Odalasvir Manufacturers

A Odalasvir manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Odalasvir, including repackagers and relabelers. The FDA regulates Odalasvir manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Odalasvir API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Odalasvir Suppliers

A Odalasvir supplier is an individual or a company that provides Odalasvir active pharmaceutical ingredient (API) or Odalasvir finished formulations upon request. The Odalasvir suppliers may include Odalasvir API manufacturers, exporters, distributors and traders.

Odalasvir GMP

Odalasvir Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Odalasvir GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Odalasvir GMP manufacturer or Odalasvir GMP API supplier for your needs.

Odalasvir CoA

A Odalasvir CoA (Certificate of Analysis) is a formal document that attests to Odalasvir's compliance with Odalasvir specifications and serves as a tool for batch-level quality control.

Odalasvir CoA mostly includes findings from lab analyses of a specific batch. For each Odalasvir CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Odalasvir may be tested according to a variety of international standards, such as European Pharmacopoeia (Odalasvir EP), Odalasvir JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Odalasvir USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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