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Find Drugs in Development News & Deals for OATD-01

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Details:

OATD-01 is an oral, small molecule inhibitor of chitinase-1 (CHIT1), which is being evaluated for the treatment of patients with acute pulmonary sarcoidosis.


Lead Product(s): OATD-01

Therapeutic Area: Immunology Product Name: OATD-01

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 22, 2024

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OATD-01, is an oral, once-daily, first-in-class highly selective CHIT1 inhibitor for the treatment of pulmonary sarcoidosis. The inhibition of CHIT1 by OATD‑01 has been shown to reduce inflammation & fibrosis.


Lead Product(s): OATD-01

Therapeutic Area: Immunology Product Name: OATD-01

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 24, 2023

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OATD-01, is an oral, once-daily, first-in-class highly selective CHIT1 inhibitor for the treatment of pulmonary sarcoidosis. The inhibition of CHIT1 by OATD‑01 has been shown to reduce inflammation & fibrosis.


Lead Product(s): OATD-01

Therapeutic Area: Immunology Product Name: OATD-01

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Galapagos

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 23, 2023

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Molecure has regained (at no cost) the full and exclusive rights to the results of all research, pre-clinical and clinical development performed by Galapagos with OATD-01 over the course of the last 18 months.


Lead Product(s): OATD-01

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: OATD-01

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Galapagos

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership June 23, 2022

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OncoArendi Therapeutics gains global development and commercialization rights of OncoArendi’s OATD-01. OATD-01 is a Phase 2-ready chitotriosidase/acidic mammalian chitinase inhibitor to treat Idiopathic pulmonary fibrosis and other diseases with a fibrotic component.


Lead Product(s): OATD-01

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: OATD-01

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Galapagos

Deal Size: $380.8 million Upfront Cash: $29.7 million

Deal Type: Licensing Agreement November 05, 2020

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