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1. Ammonia Chloramine
2. Monochloramine
1. Monochloramine
2. Chloramide
3. 10599-90-3
4. Monochloroamine
5. Chloroamine
6. Monochloroammonia
7. Nh2cl
8. Kw8k411a1p
9. Monochloramide
10. Chloramine, Mono-
11. Ccris 4022
12. Chloramine (inorganic Compound)
13. Hsdb 4293
14. Einecs 234-217-9
15. Cloroamonio
16. Unii-kw8k411a1p
17. Chlorinated Water (chloramine)
18. Chloramine [hsdb]
19. Chloramine [iarc]
20. Ec 234-217-9
21. Dtxsid8023842
22. Chebi:82415
23. Dtxsid00721369
24. Pubchem_57347134
25. Amy37006
26. Akos015904329
27. 12190-75-9
28. Ft-0623594
29. C19359
30. Q409375
| Molecular Weight | 51.47 g/mol |
|---|---|
| Molecular Formula | ClH2N |
| XLogP3 | 0.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 50.9875768 g/mol |
| Monoisotopic Mass | 50.9875768 g/mol |
| Topological Polar Surface Area | 26 Ų |
| Heavy Atom Count | 2 |
| Formal Charge | 0 |
| Complexity | 2 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Male Sprague-Dawley rats (220-240 g) were given 1.1 mg per animal [36Cl]-labelled chloramine [NH2 36Cl] orally as 3 mL of solution containing 370 mg/L chloramine. The peak plasma concentration of 36Cl (10.3 ug/L) was reached 8 hr after dosing, and the absorption and elimination half-lives were 2.5 hr and 38.8 hr, respectively. The distribution of radioactivity was highest in plasma and lowest in fat. Approximately 25% and 2% of the administered dose of radiolabelled chloramine was excreted in the urine and feces, respectively, during 120 hr of treatment. Only 0.35% of the administered dose of monochloramine was present in plasma as [36Cl] chloride 120 hr after treatment. No evidence for enzymatic intervention in the metabolism of monochloramine was presented.
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V84 303 (2004)
The effect of 15 uM monochloramine as hepatic function was investigated in isolated perfused male Sprague-Dawley rat liver. The uptake of monochloramine averaged 98%. Approximately 0.7% of the amount taken up by the liver was reduced by glutathione (GSH) and appeared in the bile in the form of GSH disulfide.
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V84 303 (2004)
Male Sprague-Dawley rats (220-240 g) were given 1.1 mg per animal [36Cl]-labelled chloramine [NH2 36Cl] orally as 3 mL of solution containing 370 mg/L chloramine. ...The absorption and elimination half-lives were 2.5 hr and 38.8 hr, respectively.
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V84 303 (2004)
On dissolution of the chloramines in the epithelial lining fluid, hypochlorous acid, ammonia, and oxygen-radicals are generated, all of which act as irritants. /Chloramines/
Goldfrank, L.R. (ed). Goldfrank's Toxicologic Emergencies. 7th Edition McGraw-Hill New York, New York 2002., p. 1457
ABOUT THIS PAGE
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PharmaCompass offers a list of Chloramine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Chloramine manufacturer or Chloramine supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Chloramine manufacturer or Chloramine supplier.
PharmaCompass also assists you with knowing the Chloramine API Price utilized in the formulation of products. Chloramine API Price is not always fixed or binding as the Chloramine Price is obtained through a variety of data sources. The Chloramine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A NH2Cl manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of NH2Cl, including repackagers and relabelers. The FDA regulates NH2Cl manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. NH2Cl API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A NH2Cl supplier is an individual or a company that provides NH2Cl active pharmaceutical ingredient (API) or NH2Cl finished formulations upon request. The NH2Cl suppliers may include NH2Cl API manufacturers, exporters, distributors and traders.
NH2Cl Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of NH2Cl GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right NH2Cl GMP manufacturer or NH2Cl GMP API supplier for your needs.
A NH2Cl CoA (Certificate of Analysis) is a formal document that attests to NH2Cl's compliance with NH2Cl specifications and serves as a tool for batch-level quality control.
NH2Cl CoA mostly includes findings from lab analyses of a specific batch. For each NH2Cl CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
NH2Cl may be tested according to a variety of international standards, such as European Pharmacopoeia (NH2Cl EP), NH2Cl JP (Japanese Pharmacopeia) and the US Pharmacopoeia (NH2Cl USP).
