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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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GLOBAL SALES INFORMATION

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Chemistry

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Also known as: 2055357-64-5, Jpi-547, Jpi547, U6n7333gdw, Nesuparib [inn], Jpi 547
Molecular Formula
C23H24N6O
Molecular Weight
400.5  g/mol
InChI Key
GRPXLKXGJAGYSD-UHFFFAOYSA-N
FDA UNII
U6N7333GDW

Nesuparib
NESUPARIB is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 3 investigational indications.
1 2D Structure

Nesuparib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6-[4-[(5-oxo-2,3,4,6-tetrahydro-1H-benzo[h][1,6]naphthyridin-8-yl)methyl]piperazin-1-yl]pyridine-3-carbonitrile
2.1.2 InChI
InChI=1S/C23H24N6O/c24-13-17-4-6-21(26-14-17)29-10-8-28(9-11-29)15-16-3-5-18-20(12-16)27-23(30)19-2-1-7-25-22(18)19/h3-6,12,14,25H,1-2,7-11,15H2,(H,27,30)
2.1.3 InChI Key
GRPXLKXGJAGYSD-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
U6N7333GDW
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 2055357-64-5

2. Jpi-547

3. Jpi547

4. U6n7333gdw

5. Nesuparib [inn]

6. Jpi 547

7. 6-(4-((5-oxo-1,2,3,4,5,6-hexahydrobenzo(h)(1,6)naphthyridin-8-yl)methyl)piperazin-1-yl)nicotinonitrile

8. 6-(4-((5-oxo-1,2,3,4,5,6-hexahydrobenzo[h][1,6]naphthyridin-8-yl)methyl)piperazin-1-yl)nicotinonitrile

9. Refchem:165540

10. Jpi-547 [who-dd]

11. Parp/tnk Inhibitor Jpi-547

12. Nov 1402

13. Parp1/2/tnk1/2 Inhibitor Jpi-547

14. Nov140201

15. Unii-u6n7333gdw

16. Orb1688106

17. Chembl5095245

18. Jpi 547 [who-dd]

19. Schembl18314125

20. Schembl29411324

21. Schembl30093972

22. Glxc-26951

23. Ex-a6172

24. Da-76112

25. Ms-26808

26. Hy-145584

27. Cs-0376456

28. H39853

29. 6-[4-[(1,2,3,4,5,6-hexahydro-5-oxobenzo[h]-1,6-naphthyridin-8-yl)methyl]-1-piperazinyl]-3-pyridinecarbonitrile

2.4 Create Date
2017-02-18
3 Chemical and Physical Properties
Molecular Weight 400.5 g/mol
Molecular Formula C23H24N6O
XLogP31.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area84.3
Heavy Atom Count30
Formal Charge0
Complexity733
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Looking for 2055357-64-5 / Nesuparib API manufacturers, exporters & distributors?

Nesuparib manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Nesuparib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Nesuparib manufacturer or Nesuparib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Nesuparib manufacturer or Nesuparib supplier.

API | Excipient name

Nesuparib

Synonyms

2055357-64-5, Jpi-547, Jpi547, U6n7333gdw, Nesuparib [inn], Jpi 547

Cas Number

2055357-64-5

Unique Ingredient Identifier (UNII)

U6N7333GDW

About Nesuparib

NESUPARIB is a small molecule drug with a maximum clinical trial phase of II (across all indications) and has 3 investigational indications.

Nesuparib Manufacturers

A Nesuparib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nesuparib, including repackagers and relabelers. The FDA regulates Nesuparib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nesuparib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Nesuparib Suppliers

A Nesuparib supplier is an individual or a company that provides Nesuparib active pharmaceutical ingredient (API) or Nesuparib finished formulations upon request. The Nesuparib suppliers may include Nesuparib API manufacturers, exporters, distributors and traders.

Nesuparib GMP

Nesuparib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Nesuparib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Nesuparib GMP manufacturer or Nesuparib GMP API supplier for your needs.

Nesuparib CoA

A Nesuparib CoA (Certificate of Analysis) is a formal document that attests to Nesuparib's compliance with Nesuparib specifications and serves as a tool for batch-level quality control.

Nesuparib CoA mostly includes findings from lab analyses of a specific batch. For each Nesuparib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Nesuparib may be tested according to a variety of international standards, such as European Pharmacopoeia (Nesuparib EP), Nesuparib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nesuparib USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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