Synopsis
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1. Lissamine-rhodamine Dodecanoic Acid
2. Lr-12
3. Motrem
1. Dtxsid201336482
2. 2014384-91-7
| Molecular Weight | 1342.5 g/mol |
|---|---|
| Molecular Formula | C54H83N15O21S2 |
| XLogP3 | -8.3 |
| Hydrogen Bond Donor Count | 20 |
| Hydrogen Bond Acceptor Count | 24 |
| Rotatable Bond Count | 45 |
| Exact Mass | g/mol |
| Monoisotopic Mass | g/mol |
| Topological Polar Surface Area | 634 |
| Heavy Atom Count | 92 |
| Formal Charge | 0 |
| Complexity | 2630 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 10 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Anti-Inflammatory Agents
Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)
Nangibotide targets the immunoreceptor TREM-1 (triggering receptor expressed on myeloid cells-1), and has been explored in treating inflammatory disorders like septic schock. Safety and pharmacokinetics studies have shown Nangibotide to be safe and well-tolerated in humans, while animal septic shock models have shown its ability to restore vascular function and improve survival. As of July 2020, Inotrem is recuriting patients to study Nangibotide's effects on patients with COVID-19 and systemic inflammation (NCT04429334).
Drugs in Development
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PharmaCompass offers a list of Nangibotide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Nangibotide manufacturer or Nangibotide supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Nangibotide manufacturer or Nangibotide supplier.
PharmaCompass also assists you with knowing the Nangibotide API Price utilized in the formulation of products. Nangibotide API Price is not always fixed or binding as the Nangibotide Price is obtained through a variety of data sources. The Nangibotide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Nangibotide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Nangibotide, including repackagers and relabelers. The FDA regulates Nangibotide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Nangibotide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Nangibotide supplier is an individual or a company that provides Nangibotide active pharmaceutical ingredient (API) or Nangibotide finished formulations upon request. The Nangibotide suppliers may include Nangibotide API manufacturers, exporters, distributors and traders.
Nangibotide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Nangibotide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Nangibotide GMP manufacturer or Nangibotide GMP API supplier for your needs.
A Nangibotide CoA (Certificate of Analysis) is a formal document that attests to Nangibotide's compliance with Nangibotide specifications and serves as a tool for batch-level quality control.
Nangibotide CoA mostly includes findings from lab analyses of a specific batch. For each Nangibotide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Nangibotide may be tested according to a variety of international standards, such as European Pharmacopoeia (Nangibotide EP), Nangibotide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Nangibotide USP).
