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Chemistry

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Also known as: 83919-23-7, Asmanex, Nasonex, Elocon, Monovo, Sch 32088
Molecular Formula
C27H30Cl2O6
Molecular Weight
521.4  g/mol
InChI Key
WOFMFGQZHJDGCX-ZULDAHANSA-N
FDA UNII
04201GDN4R

Mometasone Furoate
A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.
1 2D Structure

Mometasone Furoate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
2.1.2 InChI
InChI=1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1
2.1.3 InChI Key
WOFMFGQZHJDGCX-ZULDAHANSA-N
2.1.4 Canonical SMILES
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C
2.1.5 Isomeric SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C
2.2 Other Identifiers
2.2.1 UNII
04201GDN4R
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Asmanex

2. Asmanex Twisthaler

3. Elocon

4. Furoate Monohydrate, Mometasone

5. Furoate, Mometasone

6. Mometasone

7. Mometasone Furoate Monohydrate

8. Monohydrate, Mometasone Furoate

9. Nasonex

10. Rinelon

11. Sch 32088

12. Sch-32088

13. Sch32088

14. Twisthaler, Asmanex

2.3.2 Depositor-Supplied Synonyms

1. 83919-23-7

2. Asmanex

3. Nasonex

4. Elocon

5. Monovo

6. Sch 32088

7. Mometasone 17-furoate

8. Sinuva

9. Mometasone Furoate Anhydrous

10. Sch32088

11. Sch-32088

12. Nsc-746171

13. Chembl1161

14. Lyr210

15. (8s,9r,10s,11s,13s,14s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3h-cyclopenta[a]phenanthren-17-yl Furan-2-carboxylate

16. [(8s,9r,10s,11s,13s,14s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Furan-2-carboxylate

17. Chebi:47564

18. Lyr-210

19. 04201gdn4r

20. Nsc-760077

21. (11beta,16alpha)-9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

22. Danitin

23. Ecural

24. Elomet

25. Dsstox_cid_3333

26. Asmanex Twisthaler

27. Dsstox_rid_76981

28. Dsstox_gsid_23333

29. (9beta,10alpha,11alpha,14beta,16alpha,17alpha)-9,21-dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate

30. 9,21-dichloro-11beta-hydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate

31. Elocone

32. Flumeta

33. Nosorex

34. Rimelon

35. Ovixan

36. Asmanex Hfa

37. Mometasone Fuorate

38. Mof

39. Unii-04201gdn4r

40. Mometasone-furoate

41. Ncgc00016950-01

42. Prestwick_924

43. Asmanex (tn)

44. Mometasone Furoate [usan:usp:jan]

45. Cas-83919-23-7

46. Elocon (tn)

47. Las 41002

48. Brn 4340538

49. Prestwick0_000572

50. Prestwick1_000572

51. Prestwick2_000572

52. Prestwick3_000572

53. Mometasone Furancarboxylate

54. Schembl4568

55. Bspbio_000384

56. Mometasone 17-(2-furoate)

57. Mls002153879

58. Spbio_002603

59. Mometasone Furoate (jan/usp)

60. Bpbio1_000424

61. Mometasone Furoate [mi]

62. Dtxsid4023333

63. Mometasone Furoate [jan]

64. Mometasone Furoate [usan]

65. Hms1569d06

66. Hms2096d06

67. Hms2235i14

68. Hms3713d06

69. Mometasone Furoate [vandf]

70. Mometasone Furoate [mart.]

71. Mometasone Furoate [usp-rs]

72. Mometasone Furoate [who-dd]

73. Zinc3938677

74. Tox21_110705

75. Ac-941

76. Bdbm50148733

77. Mfcd00866003

78. Nsc746171

79. S1987

80. Mometasone Furoate, >=98% (hplc)

81. Akos015994732

82. Tox21_110705_1

83. Ccg-220572

84. Db14512

85. Ks-1275

86. Mometasone Furoate [green Book]

87. Nsc 746171

88. Nsc 760077

89. 9,21-dichloro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17-(2-furoate)

90. Mometasone Furoate [orange Book]

91. Mometasone Furoate [ep Monograph]

92. Ncgc00179578-01

93. Ncgc00179578-03

94. Ncgc00179578-04

95. (11beta,16alpha)-9,21-dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate

96. Dulera Component Mometasone Furoate

97. Hy-13693

98. Mometasone Furoate [usp Monograph]

99. Smr001233233

100. M2354

101. Mometasone Furoate Component Of Dulera

102. C07817

103. D00690

104. Mometasone Furoate 1000 Microg/ml In Methanol

105. 919m237

106. A840685

107. Mometasone Furoate 100 Microg/ml In Acetonitrile

108. Sr-01000841209

109. Lyr-220 Active Component Mometasone Furoate

110. Q-101380

111. Q1044248

112. Sr-01000841209-2

113. Brd-k60640630-001-03-7

114. Brd-k60640630-001-11-0

115. Mometasone Furoate, European Pharmacopoeia (ep) Reference Standard

116. Mometasone Furoate, United States Pharmacopeia (usp) Reference Standard

117. 11?,16?)-9,21-dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl 2-furoate

118. Mometasone Furoate, Pharmaceutical Secondary Standard; Certified Reference Material

119. (11.beta.,16.alpha.)-9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

120. [(8s,9r,10s,11s,13s,14s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Furan-2-carboxylate;mometasone Furoate

121. [(9r,10s,11s,13s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Furan-2-carboxylate

122. 9,21-dichloro-11.beta.,17-dihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione 17-(2-furoate)

123. Pregna-1,20-dione, 9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-, (11.beta.,16.alpha.)-

124. Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methyl-, (11.beta.,16.alpha.)

125. Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methyl-, (11beta,16alpha)-

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 521.4 g/mol
Molecular Formula C27H30Cl2O6
XLogP33.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass520.1419441 g/mol
Monoisotopic Mass520.1419441 g/mol
Topological Polar Surface Area93.8 Ų
Heavy Atom Count35
Formal Charge0
Complexity1020
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameElocon
Drug LabelELOCON (mometasone furoate) Ointment, 0.1% contains mometasone furoate for topical use. Mometasone furoate is a synthetic corticosteroid with anti-inflammatory activity.Chemically, mometasone furoate is 9,21-dichloro-11,17-dihydroxy-16-methylpr...
Active IngredientMometasone furoate
Dosage FormLotion; Ointment; Cream
RouteTopical
Strength0.1%
Market StatusPrescription
CompanyMerck Sharp Dohme

2 of 6  
Drug NameMometasone furoate
PubMed HealthMometasone
Drug ClassesAnti-Inflammatory, Corticosteroid, Strong
Drug LabelMometasone furoate, the active component of the ASMANEX TWISTHALER product, is a corticosteroid with the chemical name 9,21-dichloro-11(Beta),17-dihydroxy-16(alpha)-methylpregna-1,4-diene-3,20-dione 17-(2-furoate) and the following chemical structure...
Active IngredientMometasone furoate
Dosage FormOintment; Cream; Lotion
RouteTopical
Strength0.1%
Market StatusPrescription
CompanyTaro; Glenmark Generics; Fougera Pharms; Perrigo; Perrigo New York; Tolmar; G And W Labs

3 of 6  
Drug NameNasonex
Drug LabelMometasone furoate monohydrate, the active component of NASONEX Nasal Spray, 50 mcg, is an anti-inflammatory corticosteroid having the chemical name, 9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione17-(2 furoate) monohydrate, an...
Active IngredientMometasone furoate monohydrate
Dosage FormSpray, metered
RouteNasal
Strengtheq 0.05mg base/spray
Market StatusPrescription
CompanyMerck Sharp Dohme

4 of 6  
Drug NameElocon
Drug LabelELOCON (mometasone furoate) Ointment, 0.1% contains mometasone furoate for topical use. Mometasone furoate is a synthetic corticosteroid with anti-inflammatory activity.Chemically, mometasone furoate is 9,21-dichloro-11,17-dihydroxy-16-methylpr...
Active IngredientMometasone furoate
Dosage FormLotion; Ointment; Cream
RouteTopical
Strength0.1%
Market StatusPrescription
CompanyMerck Sharp Dohme

5 of 6  
Drug NameMometasone furoate
PubMed HealthMometasone
Drug ClassesAnti-Inflammatory, Corticosteroid, Strong
Drug LabelMometasone furoate, the active component of the ASMANEX TWISTHALER product, is a corticosteroid with the chemical name 9,21-dichloro-11(Beta),17-dihydroxy-16(alpha)-methylpregna-1,4-diene-3,20-dione 17-(2-furoate) and the following chemical structure...
Active IngredientMometasone furoate
Dosage FormOintment; Cream; Lotion
RouteTopical
Strength0.1%
Market StatusPrescription
CompanyTaro; Glenmark Generics; Fougera Pharms; Perrigo; Perrigo New York; Tolmar; G And W Labs

6 of 6  
Drug NameNasonex
Drug LabelMometasone furoate monohydrate, the active component of NASONEX Nasal Spray, 50 mcg, is an anti-inflammatory corticosteroid having the chemical name, 9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione17-(2 furoate) monohydrate, an...
Active IngredientMometasone furoate monohydrate
Dosage FormSpray, metered
RouteNasal
Strengtheq 0.05mg base/spray
Market StatusPrescription
CompanyMerck Sharp Dohme

4.2 Drug Indication

There are 3 formulations of mometasone furoate with various indications. The inhaler is indicated for prophylaxis of asthma in patients 4 years. The nasal spray is indicated for treating nasal symptoms of allergic rhinitis in patients 2 years, treating symptoms of nasal congestion from seasonal allergic rhinitis in patients 2 years, treating nasal polyps in patients 18 years, and prophylaxis of seasonal allergic rhinitis in patients 12 years. The ointment is indicated for symptomatic treatment of dermatitis and pruritis in patients 2 years.


FDA Label


Seasonal and perennial allergic rhinitis


5 Pharmacology and Biochemistry
5.1 Pharmacology

Mometasone is a synthetic corticosteroid with an affinity for glucocorticoid receptors 22 times higher than that of [dexamethasone]. Mometasone furoate also has a lower affinity to mineralocorticoid receptors than natural corticosteroids, making it more selective in its action. Mometasone furoate diffuses across cell membranes to activate pathways responsible for reducing inflammation.


5.2 MeSH Pharmacological Classification

Anti-Inflammatory Agents

Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)


Dermatologic Agents

Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)


Anti-Allergic Agents

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)


5.3 FDA Pharmacological Classification
5.3.1 Pharmacological Classes
Corticosteroid Hormone Receptor Agonists [MoA]; Corticosteroid [EPC]; Corticosteroid Hormone Receptor Agonists [MoA]
5.4 Absorption, Distribution and Excretion

Absorption

The mean time to peak concentration is 1.0 to 2.5 hours. Bioavailability has been reported as <1% but studies of repeat doses of inhaled corticosteroids suggest a bioavailability of 11%. The 0.1% ointment may have a bioavailability of 0.7%.


Route of Elimination

For an inhaled dose, approximately 74% is excreted in the feces and 8% is excreted in the urine.


Volume of Distribution

Steady state volume of distribution of 152L.


Clearance

The clearance rate of mometasone furoate is not readily available, though it may be close to 90L/h.


5.5 Metabolism/Metabolites

Metabolism of mometasone furoate is largely performed hepatically by cytochrome P450 3A4 producing a number of metabolites. Some of these metabolites include free mometasone and 6-beta-hydroxy-mometasone furoate.


5.6 Biological Half-Life

The terminal half life of an inhaled dose is approximately 5 hours though it has been reported as 5.8 hours by other sources.


5.7 Mechanism of Action

In asthma, mometasone is believed to inhibit mast cells, eosinophils, basophils, and lymphocytes. There is also evidence of inhibition of histamine, leukotrienes, and cytokines. Corticosteroids diffuse across cell membranes into the cytosol of cells where they bind to glucocorticoid receptors to produce their activity. Mometasone furoate has a particularly high receptor affinity compare to other corticosteroids, 22 times higher than that of [dexamethasone]. Mometasone furoate binding to a glucocorticoid receptor causes conformational changes in the receptor, separation from chaperones, and the receptor moves to the nucleus. Once at the nucleus, receptors dimerize and bind to a DNA sequence known as the glucocorticoid response element which either increases expression of anti-inflammatory molecules or inhibits expression of pro-inflammatory molecules (such as interleukins 4 and 5). Mometasone furoate also reduces inflammation by blocking transcription factors such as activator-protein-1 and nuclear factor kappa B (NF-kappaB).


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MAHARASHTRA","supplier":"STERLING S P A","supplierCountry":"ITALY","foreign_port":"ROME","customer":"GLENMARK PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"1.60","actualQuantity":"1600","unit":"GMS","unitRateFc":"5.2","totalValueFC":"9219","currency":"EURO","unitRateINR":"481","date":"01-Jun-2024","totalValueINR":"769600","totalValueInUsd":"9219","indian_port":"Delhi Air","hs_no":"29372900","bill_no":"3774029","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA, 30 SOLOMEO 06073 CORCIANO PERUGIA - ITALY ., .,ITALY ITALY","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717353000,"product":"MOMETASONE FUROATE BP (MICRONIZED) BATCH NO- MTC-002\/23 L24082A1","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"STERLING S P A","supplierCountry":"ITALY","foreign_port":"ROME","customer":"GLENMARK PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"2.35","actualQuantity":"2350","unit":"GMS","unitRateFc":"5.2","totalValueFC":"13540.5","currency":"EURO","unitRateINR":"481","date":"03-Jun-2024","totalValueINR":"1130350","totalValueInUsd":"13540.5","indian_port":"Delhi Air","hs_no":"29372900","bill_no":"3809103","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA, 30 SOLOMEO 06073 CORCIANO PERUGIA - ITALY ., .,ITALY ITALY","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731263400,"product":"MOMETASONE FUROATE MICRONIZED USP AND EP","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"STERLING S P A","supplierCountry":"ITALY","foreign_port":"ROME (ROMA), RM","customer":"GLENMARK PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"5742.9","totalValueFC":"11596.3","currency":"USD","unitRateINR":"489294","date":"11-Nov-2024","totalValueINR":"978588","totalValueInUsd":"11596.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372200","bill_no":"1007872","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME (ROMA), RM","supplierAddress":"VIA DELLA CARBONERIA 30 06073 SOLOM EO DI CORCIANO-PG ITALY, , Italy Italy","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732732200,"product":"MOMETASONE FUROATE MONOHYDRATE MICRONIZED","address":"221, GOREGAON-MULUND LINK ROAD,","city":"BHANDUP WEST, MUMBAI","supplier":"STERLING S P A","supplierCountry":"ITALY","foreign_port":"ROME","customer":"RUBICON RESEARCH LTD","customerCountry":"INDIA","quantity":"0.04","actualQuantity":"0.038","unit":"KGS","unitRateFc":"25000","totalValueFC":"960.8","currency":"USD","unitRateINR":"2133750","date":"28-Nov-2024","totalValueINR":"81082.5","totalValueInUsd":"960.8","indian_port":"Bombay Air","hs_no":"29372200","bill_no":"6940847","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA 30 06073 SOLOMEO DI CORCIANO PG ITALY IT","customerAddress":"221, GOREGAON-MULUND LINK ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744050600,"product":"MOMETASONE FUROATE ANHYDROUS IP MICRON MOMETASONE FUROATE ANHYDROUS IP MICRON","address":"TORRENT HOUSE,","city":"AHMEDABAD. GUJARAT","supplier":"ORGANON INTERNATIONAL SERVICES GMBH","supplierCountry":"SINGAPORE","foreign_port":"SINGAPORE","customer":"TORRENT PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"56000","totalValueFC":"283265.1","currency":"USD","unitRateINR":"4849600","date":"08-Apr-2025","totalValueINR":"24248000","totalValueInUsd":"283265.1","indian_port":"Bombay Air","hs_no":"29372200","bill_no":"9373744","productDescription":"API","marketType":"","country":"SINGAPORE","selfForZScoreResived":"Micronized","supplierPort":"SINGAPORE","supplierAddress":"WEYSTRASSE 20 CH-6006 LUCERNE-6006 SDNF SDNF SWITZERLAND","customerAddress":"TORRENT HOUSE,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744396200,"product":"MOMETASONE FUROATE MONOHYDRATE GRADE I(0.386 KGS)","address":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"HOVIONE FARMACIENCIA S A","supplierCountry":"PORTUGAL","foreign_port":"LISBOA","customer":"APL HEALTHCARE LTD","customerCountry":"INDIA","quantity":"0.39","actualQuantity":"0.386","unit":"KGS","unitRateFc":"50000","totalValueFC":"19525.1","currency":"USD","unitRateINR":"4330000","date":"12-Apr-2025","totalValueINR":"1671380","totalValueInUsd":"19525.1","indian_port":"APIIC MULTI PRODUCT SEZ NAIDUPET AP","hs_no":"29372200","bill_no":"9458563","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBOA","supplierAddress":"SETE CASAS 2674-506 LOURES SDNF Portugal","customerAddress":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744741800,"product":"MOMETASONE FUROATE MONOHYDRATE MICRONIZED MOMETASONE FUROATE MONOHYDRATE MICRONIZED","address":"221, GOREGAON-MULUND LINK ROAD,","city":"BHANDUP WEST, MUMBAI","supplier":"STERLING S P A","supplierCountry":"ITALY","foreign_port":"ROME","customer":"RUBICON RESEARCH LTD","customerCountry":"INDIA","quantity":"0.42","actualQuantity":"0.42","unit":"KGS","unitRateFc":"25000","totalValueFC":"10622.4","currency":"USD","unitRateINR":"2165000","date":"16-Apr-2025","totalValueINR":"909300","totalValueInUsd":"10622.4","indian_port":"Bombay Air","hs_no":"29372200","bill_no":"9526445","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA 30 06073 SOLOMEO DI CORCIANO PG ITALY IT","customerAddress":"221, GOREGAON-MULUND LINK ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1745951400,"product":"MOMETASONE FUROATE MONOHYDRATE BP\/PH EUR","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"CIPLA LTD","supplierCountry":"INDIA","foreign_port":"INDORE(EPZ\/SEZ)","customer":"CIPLA LTD","customerCountry":"INDIA","quantity":"9.70","actualQuantity":"9703.562","unit":"GMS","unitRateFc":"6.4","totalValueFC":"62209.2","currency":"USD","unitRateINR":"548.8","date":"30-Apr-2025","totalValueINR":"5325217.79","totalValueInUsd":"62209.2","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372200","bill_no":"9802092","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"INDORE(EPZ\/SEZ)","supplierAddress":"PLOT NO 9 & 10 PHARMA ZONE PHASE- II SEZ PITHAMPUR INDORE SDNF India","customerAddress":"MUMBAI CENTRAL,"}]
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30-May-2025
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DRUG PRODUCT COMPOSITIONS

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DOSAGE - OINTMENT;TOPICAL - 0.1%

USFDA APPLICATION NUMBER - 19543

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DOSAGE - CREAM;TOPICAL - 0.1% **Federal Regis...DOSAGE - CREAM;TOPICAL - 0.1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 19625

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DOSAGE - LOTION;TOPICAL - 0.1% **Federal Regi...DOSAGE - LOTION;TOPICAL - 0.1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 19796

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DOSAGE - AEROSOL, METERED;INHALATION - 0.05MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.05MG/INH

USFDA APPLICATION NUMBER - 205641

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DOSAGE - AEROSOL, METERED;INHALATION - 0.10MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.10MG/INH

USFDA APPLICATION NUMBER - 205641

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DOSAGE - AEROSOL, METERED;INHALATION - 0.20MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.20MG/INH

USFDA APPLICATION NUMBER - 205641

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DOSAGE - SPRAY, METERED;NASAL - 0.05MG/SPRAY ...DOSAGE - SPRAY, METERED;NASAL - 0.05MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 20762

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DOSAGE - POWDER;INHALATION - 0.11MG/INH

USFDA APPLICATION NUMBER - 21067

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DOSAGE - POWDER;INHALATION - 0.22MG/INH

USFDA APPLICATION NUMBER - 21067

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DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.05MG/INH

USFDA APPLICATION NUMBER - 22518

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DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.1MG/INH

USFDA APPLICATION NUMBER - 22518

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DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.2MG/INH

USFDA APPLICATION NUMBER - 22518

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ABOUT THIS PAGE

Looking for 83919-23-7 / Mometasone Furoate API manufacturers, exporters & distributors?

Mometasone Furoate manufacturers, exporters & distributors 1

22

PharmaCompass offers a list of Mometasone Furoate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Mometasone Furoate manufacturer or Mometasone Furoate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Mometasone Furoate manufacturer or Mometasone Furoate supplier.

PharmaCompass also assists you with knowing the Mometasone Furoate API Price utilized in the formulation of products. Mometasone Furoate API Price is not always fixed or binding as the Mometasone Furoate Price is obtained through a variety of data sources. The Mometasone Furoate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Mometasone Furoate

Synonyms

83919-23-7, Asmanex, Nasonex, Elocon, Monovo, Sch 32088

Cas Number

83919-23-7

Unique Ingredient Identifier (UNII)

04201GDN4R

About Mometasone Furoate

A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.

Mometasone Furoate Monohydrate Manufacturers

A Mometasone Furoate Monohydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mometasone Furoate Monohydrate, including repackagers and relabelers. The FDA regulates Mometasone Furoate Monohydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mometasone Furoate Monohydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Mometasone Furoate Monohydrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Mometasone Furoate Monohydrate Suppliers

A Mometasone Furoate Monohydrate supplier is an individual or a company that provides Mometasone Furoate Monohydrate active pharmaceutical ingredient (API) or Mometasone Furoate Monohydrate finished formulations upon request. The Mometasone Furoate Monohydrate suppliers may include Mometasone Furoate Monohydrate API manufacturers, exporters, distributors and traders.

click here to find a list of Mometasone Furoate Monohydrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Mometasone Furoate Monohydrate USDMF

A Mometasone Furoate Monohydrate DMF (Drug Master File) is a document detailing the whole manufacturing process of Mometasone Furoate Monohydrate active pharmaceutical ingredient (API) in detail. Different forms of Mometasone Furoate Monohydrate DMFs exist exist since differing nations have different regulations, such as Mometasone Furoate Monohydrate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Mometasone Furoate Monohydrate DMF submitted to regulatory agencies in the US is known as a USDMF. Mometasone Furoate Monohydrate USDMF includes data on Mometasone Furoate Monohydrate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Mometasone Furoate Monohydrate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Mometasone Furoate Monohydrate suppliers with USDMF on PharmaCompass.

Mometasone Furoate Monohydrate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Mometasone Furoate Monohydrate Drug Master File in Japan (Mometasone Furoate Monohydrate JDMF) empowers Mometasone Furoate Monohydrate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Mometasone Furoate Monohydrate JDMF during the approval evaluation for pharmaceutical products. At the time of Mometasone Furoate Monohydrate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Mometasone Furoate Monohydrate suppliers with JDMF on PharmaCompass.

Mometasone Furoate Monohydrate KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Mometasone Furoate Monohydrate Drug Master File in Korea (Mometasone Furoate Monohydrate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Mometasone Furoate Monohydrate. The MFDS reviews the Mometasone Furoate Monohydrate KDMF as part of the drug registration process and uses the information provided in the Mometasone Furoate Monohydrate KDMF to evaluate the safety and efficacy of the drug.

After submitting a Mometasone Furoate Monohydrate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Mometasone Furoate Monohydrate API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Mometasone Furoate Monohydrate suppliers with KDMF on PharmaCompass.

Mometasone Furoate Monohydrate CEP

A Mometasone Furoate Monohydrate CEP of the European Pharmacopoeia monograph is often referred to as a Mometasone Furoate Monohydrate Certificate of Suitability (COS). The purpose of a Mometasone Furoate Monohydrate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Mometasone Furoate Monohydrate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Mometasone Furoate Monohydrate to their clients by showing that a Mometasone Furoate Monohydrate CEP has been issued for it. The manufacturer submits a Mometasone Furoate Monohydrate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Mometasone Furoate Monohydrate CEP holder for the record. Additionally, the data presented in the Mometasone Furoate Monohydrate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Mometasone Furoate Monohydrate DMF.

A Mometasone Furoate Monohydrate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Mometasone Furoate Monohydrate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Mometasone Furoate Monohydrate suppliers with CEP (COS) on PharmaCompass.

Mometasone Furoate Monohydrate WC

A Mometasone Furoate Monohydrate written confirmation (Mometasone Furoate Monohydrate WC) is an official document issued by a regulatory agency to a Mometasone Furoate Monohydrate manufacturer, verifying that the manufacturing facility of a Mometasone Furoate Monohydrate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Mometasone Furoate Monohydrate APIs or Mometasone Furoate Monohydrate finished pharmaceutical products to another nation, regulatory agencies frequently require a Mometasone Furoate Monohydrate WC (written confirmation) as part of the regulatory process.

click here to find a list of Mometasone Furoate Monohydrate suppliers with Written Confirmation (WC) on PharmaCompass.

Mometasone Furoate Monohydrate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Mometasone Furoate Monohydrate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Mometasone Furoate Monohydrate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Mometasone Furoate Monohydrate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Mometasone Furoate Monohydrate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Mometasone Furoate Monohydrate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Mometasone Furoate Monohydrate suppliers with NDC on PharmaCompass.

Mometasone Furoate Monohydrate GMP

Mometasone Furoate Monohydrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Mometasone Furoate Monohydrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mometasone Furoate Monohydrate GMP manufacturer or Mometasone Furoate Monohydrate GMP API supplier for your needs.

Mometasone Furoate Monohydrate CoA

A Mometasone Furoate Monohydrate CoA (Certificate of Analysis) is a formal document that attests to Mometasone Furoate Monohydrate's compliance with Mometasone Furoate Monohydrate specifications and serves as a tool for batch-level quality control.

Mometasone Furoate Monohydrate CoA mostly includes findings from lab analyses of a specific batch. For each Mometasone Furoate Monohydrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Mometasone Furoate Monohydrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Mometasone Furoate Monohydrate EP), Mometasone Furoate Monohydrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mometasone Furoate Monohydrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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