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1. 1,5 Pentanediamine
2. 1,5-pentanediamine
3. Biodex 1
4. Pentamethylenediamine
1. Pentane-1,5-diamine
2. 1,5-diaminopentane
3. 462-94-2
4. 1,5-pentanediamine
5. Pentamethylenediamine
6. Cadaverin
7. 1,5-pentamethylenediamine
8. Animal Coniine
9. Ai3-26937
10. Brn 1697256
11. 1,5-diamino-n-pentane
12. L90ben6oll
13. Chembl119296
14. Chebi:18127
15. N2p
16. Pentamethylenediamine Dihydrochloride
17. Einecs 207-329-0
18. Unii-l90ben6oll
19. Hsdb 7866
20. Cadaverine, 95%
21. Mfcd00008239
22. Pentane-1,5-damne
23. 1,5-diamino-pentane
24. Biodex 1-
25. 1,5-amylene Diamine
26. Cadaverine [mi]
27. 5-azaniumylpentylammonium
28. Alpha,omega-pentanediamine
29. Bmse000072
30. Ec 207-329-0
31. Schembl21367
32. 4-04-00-01310 (beilstein Handbook Reference)
33. Cadaverine, Analytical Standard
34. H2n(ch2)5nh2
35. Schembl5495920
36. Dtxsid5075448
37. Zinc1529253
38. Bbl027704
39. Bdbm50323741
40. Stl372961
41. Akos005169829
42. Am61576
43. Cadaverine, Purum, >=97.0% (gc)
44. Ccg-266036
45. Db03854
46. Ncgc00166285-01
47. As-30673
48. Db-051367
49. Ft-0600435
50. C01672
51. 462d942
52. A827022
53. Q161555
54. J-523897
55. 1948270a-6d1b-4f40-bc13-9b680ed17b17
| Molecular Weight | 102.18 g/mol |
|---|---|
| Molecular Formula | C5H14N2 |
| XLogP3 | -0.6 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 4 |
| Exact Mass | 102.115698455 g/mol |
| Monoisotopic Mass | 102.115698455 g/mol |
| Topological Polar Surface Area | 52 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 25.3 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
The urinary excretion of histamine, methylhistamine, putrescine, cadaverine, spermidine and spermine was examined before, during and after pregnancy in rats. During the last third of undisturbed pregnancy a distinct and steep rise occurred in the excretion of all amines studied except spermine. The peak values were found a few days before the birth of the young. In spermidine excretion a second peak was observed one or two days after delivery. Before and during the first 2 weeks of gestation on a molar basis putrescine excretion was the greatest one. During the last trimester histamine was excreted in the largest amount. Under the influence of the diamine oxidase inhibitor aminoguanidine the general pattern of excretion of diamines and polyamines in pregnant rats remained essentially unchanged but the total amount excreted increased. Most conspicuous was the great elevation of urinary contents of putrescine and cadaverine.
PMID:745086 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1281758 Andersson AC et al; J Physiol 285: 311-24 (1978)
Cadaverine has been shown to be present in the central nervous system (CNS) ... Its concentration in the whole brain varies during behavioral sleep in mammals and during hibernation in molluscs. ... Cadaverine has been considered a non-metabolite of the brain, and its presence in the body was believed to be due almost entirely to bacterial decarboxylation of lysine in the intestine. In slices of mouse brain, exogenous cadaverine accumulates against a concentration gradient and can reach a concentration ten times greater in the tissue than in the surrounding medium. The question has been therefore: does the cadaverine in the brain originate from an exogenous source; is it formed and resorbed in the intestine? Assaying cadaverine in axenic mice, /it has been/ found that this is not the case, and that there is an endogenous source of cadaverine in the mouse.
Matej S-K, Dolezalova H; Nature 252: 158-9 (1974)
It is a precursor of piperidine, which has been linked with some functional stages of the CNS. Cadaverine is the source of much of the piperidine excreted in the urine.
Matej S-K, Dolezalova H; Nature 252: 158-9 (1974)
Cadaverine ... a relatively nontoxic ptomaine, C5H14N2, formed by decarboxylation of lysine; it is sometimes one of the products of Vibrio proteus and of V. cholerae, and occasionally found in the urine in cystinuria, where it causes an unpleasant odor.
Merck Source; Resource Library Powered by Dorland's Medical Dictionary for Healthcare Consumers. Available from, as of November 19, 2010: https://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/misc/dmd-a-b-000.htm
Cadaverine is synthesized from lysine in a one-step reaction with lysine decarboxylase (LDC).
ChemEurope.com; Polyamine. In Encyclopedia of Chemistry. Available from, as of November 19, 2010: https://www.chemeurope.com/lexikon/e/Polyamine/
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