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1. 1,3,5-triazine-2,4,6-triamine
2. 2,4,6-triamino-s-triazine
3. Melamine Bis(oxymethyl)phosphonic Acid Salt
4. Melamine Oxalate (1:1)
5. Melamine Phosphate
6. Melamine Sulfate (1:1)
7. Melamine Sulfate (1:2)
8. Melamine Sulfate (2:1), Dihydrate
9. Melamine Sulfate (4:1), Tetrahydrate
10. Melamine Sulfite (1:1)
11. Melamine Sulfite (2:1), Dihydrate
12. Melamine Sulfite (2:1), Tetrahydrate
13. Melaminium Acetate Acetic Acid Solvate
14. Melaminium Citrate
1. 1,3,5-triazine-2,4,6-triamine
2. 108-78-1
3. Cyanuramide
4. Cyanurotriamide
5. Cyanurotriamine
6. Isomelamine
7. Theoharn
8. Teoharn
9. Triaminotriazine
10. Cyanuric Triamide
11. Hicophor Pr
12. S-triazinetriamine
13. Aero
14. 2,4,6-triamino-s-triazine
15. Yukamelamine
16. Pluragard
17. Cymel
18. 2,4,6-triamino-1,3,5-triazine
19. Virset 656-4
20. Spinflam Ml 94m
21. 2,4,6-triaminotriazine
22. Pluragard C 133
23. Adk Stab Zs 27
24. Mark Zs 27
25. Dg 002 (amine)
26. Melamine Monomer
27. Nci-c50715
28. Cyanurtriamide
29. S-triazine, 2,4,6-triamino-
30. 1,3,5-triazine-2,4,6(1h,3h,5h)-triimine
31. Zs 27
32. Nsc 2130
33. Dg 002
34. Sym-triaminotriazine
35. Dtxsid6020802
36. 1246816-14-7
37. N3gp2ysd88
38. Chebi:27915
39. Melamine 100 Microg/ml In Water
40. Nsc-2130
41. 1,3,5-triazine-2,4,6-triamine (melamine)
42. Melamine 100 Microg/ml In Acetonitrile/water
43. Melamine-13c3,15n3
44. Melamin
45. S-triaminotriazine
46. Ccris 373
47. Hsdb 2648
48. Einecs 203-615-4
49. Unii-n3gp2ysd88
50. Brn 0124341
51. 2,4,6-triamino Sym-triazine
52. Ai3-14883
53. Ax2
54. Melamine, 99%
55. 2,6-triaminotriazine
56. Cymel (salt/mix)
57. Melamine [hsdb]
58. Melamine [iarc]
59. Melamine [inci]
60. Metformin Ep Impurity D
61. 2,4,6-triamino-1,3,5-triazine Monomer
62. Melamine [mi]
63. Dsstox_cid_802
64. 2,6-triamino-s-triazine
65. Melamine [usp-rs]
66. 1,3,5-triazine-2,4,6(1h,3h,5h)triimine
67. Ec 203-615-4
68. S-triazine,4,6-triamino-
69. Dsstox_rid_75795
70. Dsstox_gsid_20802
71. Schembl25853
72. Melamine, Analytical Standard
73. 4-26-00-01253 (beilstein Handbook Reference)
74. 5432-64-4
75. Bidd:er0287
76. Chembl1231106
77. Schembl12192199
78. 1,5-triazine-2,4,6-triamine
79. 2,6-triamino-1,3,5-triazine
80. Nsc2130
81. Nsc8152
82. Zinc897751
83. Hy-y1117
84. Nsc-8152
85. Wln: T6n Cn Enj Bz Dz Fz
86. Tox21_200503
87. 1,3,5-triazinane-2,4,6-triimine
88. Bbl000010
89. Melamine 100 Microg/ml In Methanol
90. Mfcd00006055
91. S9212
92. Stk378738
93. [1,3,5]triazine-2,4,6-triamine
94. 1,3, 5-triazine-2,4,6-triamine
95. 2,4, 6-triamino-1,3,5-triazine
96. Akos005448714
97. Ccg-266105
98. Ncgc00164014-01
99. Ncgc00164014-02
100. Ncgc00258057-01
101. 2,4,6-triamino-1,3,5-triazine;melamine;1,3,5-triazine-2,4,6-triamine;[1,3,5]triazine-2,4,6-triamine;s-triazine, 4,6-diamino-1,2-dihydro-2-imino-;2,4,6-triamino-1,3,5-triazine Melamine 1,3,5-triazine-2,4,6-triamine [1,3,5]triazine-2,4,6-triamine S-triazine, 4,6-diamino-1,2-dihydro-2-imino-
102. Ac-34715
103. Cas-108-78-1
104. Vs-00405
105. 1,3,5-triazine-2,4,6-triamine Monomer
106. Melamine 1.0 Mg/ml In Dimethyl Sulfoxide
107. Cs-0016866
108. Ft-0609833
109. Ft-0670982
110. Ft-0670983
111. Melamine; 1,3,5-triazine-2,4,6-triamine
112. T0337
113. 1,5-triazine-2,4,6(1h,3h,5h)-triimine
114. 4,6-diamino-1,2-dihydro-2-imino-s-triazine
115. C08737
116. E76265
117. S-triazine, 4,6-diamino-1,2-dihydro-2-imino-
118. Q212553
119. J-002191
120. 1,3,5-triazine-2,4,6-triamine (acd/name 4.0)
121. 2,4,6-triamino-1,3,5-triazine, Sym-triaminotriazine
122. Metformin Hydrochloride Impurity D [ep Impurity]
123. Melamine, >=95.0% (hplc), Pharmaceutical Impurity Standard
124. Melamine, United States Pharmacopeia (usp) Reference Standard
125. N,n',n''-tri-2-pyridinyl-1,3,5-triazine-2,4,6-triamine
126. Melamine, Pharmaceutical Secondary Standard; Certified Reference Material
| Molecular Weight | 126.12 g/mol |
|---|---|
| Molecular Formula | C3H6N6 |
| XLogP3 | -1.4 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 0 |
| Exact Mass | 126.06539422 g/mol |
| Monoisotopic Mass | 126.06539422 g/mol |
| Topological Polar Surface Area | 117 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 63.3 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
... A single oral dose of 0.025 mCi (0.38 mg) [14C]melamine /was administered/ to adult male Fischer 344 rats. Within the first 24 hr, 90% of the administered dose was excreted in the urine. Negligible radioactivity appeared in breath and feces. There was little difference in blood, liver or plasma concentrations of 14C, suggesting that melamine distributes in body water. The only organs showing radioactivity levels much higher than plasma were the kidney and bladder. The bladder level was by far the highest, a finding probably due either to back diffusion from urine or to contamination of bladder tissue with urine. Virtually no residual radioactivity was observed in tissues examined at 24 hr or later. The elimination-phase half-life calculated from plasma data, 2.7 hr, was in good agreement with the urinary-excretion half-life of 3.0 hr. The renal clearance of melamine was 2.5 mL/min.
PMID:6686586 Mast RW et al; Food Chem Toxicol 21 (6): 807-10 (1983)
... Following oral administration of 250 mg/kg melamine to rats, 50% of the mother compound was excreted with the urine within 6 hrs. ... Crystals found in the urine were composed of dimelamine monophosphate, amounting to nearly 20% of the administered dose. After feeding melamine to dogs, 60 - 86.5% of the mother compound was recovered in the urine within 24 hrs. ...
European Chemicals Bureau; IUCLID Dataset, Melamine (CAS # 108-78-1) p.79 Available from, as of June 26, 2007: https://esis.jrc.ec.europa.eu/
Doses of 2.4 g/kg cause diuresis & elimination of fine crystals of dimelamine monophosphate in urine.
Lefaux, R. Practical Toxicology of Plastics. Cleveland: CRC Press Inc., 1968., p. 330
After administration of a single oral dose of 0.38 mg (14)C-melamine to adult male Fischer 344/N rats, 90% of the administered dose was excreted in the urine within the first 24 hours. Negligible radioactivity was detected in exhaled air and feces; and radioactivity was concentrated in the kidney and bladder. Virtually no residual radioactivity was observed in tissue after 24 hours or more. Chromatography of the radioactivity found in plasma or urine indicated that melamine is not metabolized in rats.
IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V39 340 (1986)
Toxicokinetic studies in rats given 14C-labelled cyromazine as single and repeated oral doses showed that the active substance is rapidly and almost completely absorbed from the gastrointestinal tract and distributed to all organs and tissues. ... Cyromazine was incompletely metabolized, essentially by methylation, hydroxylation or Ndealkylation. The major component present was cyromazine, which accounted for 71-72% of the radiolabel; a further 7% was attributable to melamine, 8-11% to hydroxy-cyromazine and methylcyromazine.
Joint FAO/WHO Meeting on Pesticide Residues in Food. FAO Plant Production and Protection Paper 187; Cyromazine p.102 (October 2006) Available from: https://www.fao.org/ag/agp/agpp/Pesticid/Default.htm
... A single oral dose of 0.025 mCi (0.38 mg) [14C]melamine /was administered/ to adult male Fischer 344 rats. ... Radioactivity in plasma or urine co-chromatographed with that of the dosing solution, indicating that melamine is not metabolized in the male Fischer 344 rat.
PMID:6686586 Mast RW et al; Food Chem Toxicol 21 (6): 807-10 (1983)
Crystalluria was due to excretion of dimelamine-monophosphate crystals.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 4:1335
... A single oral dose of 0.025 mCi (0.38 mg) [14C]melamine /was administered/ to adult male Fischer 344 rats. ... The elimination-phase half-life calculated from plasma data, 2.7 hr, was in good agreement with the urinary-excretion half-life of 3.0 hr. ...
PMID:6686586 Mast RW et al; Food Chem Toxicol 21 (6): 807-10 (1983)
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