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MolPort-001-759-819

MolPort-001-759-819

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Also known as: 127-08-2, Diuretic salt, Acetic acid, potassium salt, Potassium ethanoate, Potassium;acetate, Fema no. 2920

Molecular Formula

C₂H₃KO₂

Molecular Weight

98.14 g/mol

InChI Key

SCVFZCLFOSHCOH-UHFFFAOYSA-M

FDA UNII

M911911U02

A potassium salt used to replenish ELECTROLYTES, for restoration of WATER-ELECTROLYTE BALANCE, as well as a urinary and systemic alkalizer, which can be administered orally or by intravenous infusion. Formerly, it was used in DIURETICS and EXPECTORANTS.

1 2D Structure

MolPort-001-759-819

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

potassium;acetate

2.1.2 InChI

InChI=1S/C2H4O2.K/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

2.1.3 InChI Key

SCVFZCLFOSHCOH-UHFFFAOYSA-M

2.1.4 Canonical SMILES

CC(=O)[O-].[K+]

2.2 Other Identifiers

2.2.1 UNII

M911911U02

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Acetate, Potassium

2.3.2 Depositor-Supplied Synonyms

1. 127-08-2

2. Diuretic Salt

3. Acetic Acid, Potassium Salt

4. Potassium Ethanoate

5. Potassium;acetate

6. Fema No. 2920

7. Koac

8. Acetic Acid Potassium Salt

9. Kali Aceticum

10. Potassium Acetates

11. Acok

12. Mfcd00012458

13. Acetic Acid, Potassium Salt (1:1)

14. Ch3co2k

15. E261

16. Ins No.261

17. Potassium Acetate Solution, 5m

18. Chebi:32029

19. Ins-261

20. Ins-261(i)

21. E-261

22. M911911u02

23. Octan Draselny [czech]

24. Potassiumacetate

25. Potassium Acetate [jan]

26. Potassium Acetate (tn)

27. Einecs 204-822-2

28. Potassium Acetate In Plastic Container

29. Kaliumazetat

30. Potassium Acetate [usp:jan]

31. Potasium Acetate

32. Potassium Acetat

33. Potassium-acetate

34. Unii-m911911u02

35. Meco2k

36. Ch3cook

37. Potassium Acetate Solution

38. Dsstox_cid_7043

39. Ec 204-822-2

40. Dsstox_rid_78289

41. Dsstox_gsid_27043

42. Kali Aceticum [hpus]

43. Potassium Acetate (jan/usp)

44. Potassium Acetate [ii]

45. Potassium Acetate [mi]

46. Chembl1201058

47. Dtxsid7027043

48. Potassium Acetate [fhfi]

49. Potassium Acetate [inci]

50. Hy-y0319b

51. Potassium Acetate [vandf]

52. Potassium Acetate [mart.]

53. Potassium Acetate A.c.s. Reagent

54. Potassium Acetate [usp-rs]

55. Potassium Acetate [who-dd]

56. Potassium Acetate, Biochemical Grade

57. Tox21_202740

58. S4843

59. Akos003052760

60. Akos015901668

61. Ccg-266027

62. Cs-w020131

63. Db14498

64. Potassium Acetate [orange Book]

65. Potassium Acetate Acs Grade 1kg

66. Potassium Acetate, 8m Aqueous Solution

67. Potassium Acetate [ep Monograph]

68. Ncgc00260288-01

69. Potassium Acetate [usp Monograph]

70. Bp-21033

71. Cas-127-08-2

72. Ft-0645118

73. P2786

74. 4-chloro-n-furfuryl-5-sulfamoylanthranlic Acid

75. D01154

76. Potassium Acetate, Trace Metals Grade 99.98%

77. Potassium Acetate, 1m Aqueous Solution, Ph 7.5

78. Q409199

79. J-005461

80. Potassium Acetate, 8m Aqueous Solution, Rnase Free

81. Potassium Acetate, 1m Aqueous Solution, Ph 7.5, Rnase Free

2.4 Create Date

2005-03-27

3 Chemical and Physical Properties

Molecular Formula	C₂H₃KO₂
Molecular Weight	98.14 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	97.97701082 g/mol
Monoisotopic Mass	97.97701082 g/mol
Topological Polar Surface Area	40.1 Å²
Heavy Atom Count	5
Formal Charge	0
Complexity	34.6
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Potassium acetate in plastic container
Active Ingredient	Potassium acetate
Dosage Form	Injectable
Route	Injection
Strength	2meq/ml
Market Status	Prescription
Company	Hospira

2 of 2
Drug Name	Potassium acetate in plastic container
Active Ingredient	Potassium acetate
Dosage Form	Injectable
Route	Injection
Strength	2meq/ml
Market Status	Prescription
Company	Hospira

4.2 Drug Indication

Potassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions.

5 Pharmacology and Biochemistry

5.1 FDA Pharmacological Classification

5.1.1 Pharmacological Classes

Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Osmotic Laxative [EPC]; Potassium Compounds [CS]; Potassium Salt [EPC]; Increased Large Intestinal Motility [PE]

5.2 ATC Code

B - Blood and blood forming organs

B05 - Blood substitutes and perfusion solutions

B05X - I.v. solution additives

B05XA - Electrolyte solutions

B05XA17 - Potassium acetate

5.3 Absorption, Distribution and Excretion

Route of Elimination

Mostly urine but also skin and feces.

5.4 Mechanism of Action

Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium is maintained by ion pumps in the cell membrane. The cell membrane potential created by potassium and sodium ions allows the cell generate an action potentiala "spike" of electrical discharge. The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function. Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of acidity.