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1. 7646-85-7
2. Zinc Dichloride
3. Butter Of Zinc
4. Zinc(ii) Chloride
5. Zinc Butter
6. Zinkchloride
7. Zintrace
8. Zinc Chloride (zncl2)
9. Zinc Chloride Fume
10. Zinc Chloride, (solution)
11. Mfcd00011295
12. Zinc (chlorure De)
13. Zinco (cloruro Di)
14. Zinc Chloride, Solution
15. Zinc Chloride, Ultra Dry
16. Zinc Chloride Solution Anhydrous
17. Zinc Chloride Solution, 1.9 M In 2-methyltetrahydrofuran
18. Zine Dichloride
19. Zinkchlorid [german]
20. Zinkchloride [dutch]
21. Zinc Chloride Solution
22. Caswell No. 910
23. Chlorure De Zinc [french]
24. Zinc (chlorure De) [french]
25. Ccris 3509
26. Zinc Chloride 0.1 M Solution
27. Zinco (cloruro Di) [italian]
28. Hsdb 1050
29. Einecs 231-592-0
30. Un1840
31. Un2331
32. Zinc Chloride (tn)
33. Epa Pesticide Chemical Code 087801
34. Nsc 529648
35. Zinc Muriate, Solution
36. Ai3-04470
37. Zinc Chloride [usp:jan]
38. Dsstox_cid_15013
39. Dsstox_rid_79237
40. Wln: Zn G2
41. Dsstox_gsid_35013
42. Zinc Chloride (jp17/usp)
43. Zinc Chloride, Lr, >=97%
44. Unii-86q357l16b
45. Zinc Chloride, P.a., 97.0%
46. Zinc Chloride In Plastic Container
47. Tox21_301492
48. Zinc Chloride, 1.9m In 2-methf
49. Zinc Chloride, For Molecular Biology
50. Zinc Chloride, 25mm Aqueous Solution
51. Akos016017250
52. Zinc Chloride, 0.5m Solution In Thf
53. Zinc Chloride, 0.7m Solution In Thf
54. Zinc Chloride, Acs Reagent, >=97%
55. Zinc Chloride, Reagent Grade, >=98%
56. Zinc Chloride Solution, 0.5 M In Thf
57. Ncgc00255612-01
58. Zinc Chloride (99.99%-zn) Puratrem
59. Cas-7646-85-7
60. Ft-0645122
61. Zinc Chloride, 99.999% Trace Metals Basis
62. Zinc Chloride, Saj First Grade, >=95.0%
63. Zinc Chloride, Jis Special Grade, >=98.0%
64. D02058
65. Ec 231-592-0
66. Zinc Chloride Solution, 1.0 M In Diethyl Ether
67. Zinc Chloride, Solution [un1840] [corrosive]
68. Q204714
69. Zinc Chloride, Anhydrous [un2331] [corrosive]
70. Brd-k46586998-001-01-1
71. Zinc Chloride, Bioreagent, For Molecular Biology, >=97.0%
72. Zinc Chloride, Anhydrous, Powder, >=99.995% Trace Metals Basis
73. Zinc Chloride, Anhydrous, Free-flowing, Redi-dri(tm), Acs Reagent, >=97%
74. Zinc Chloride, 1m In Diethyl Ether, Packaged Under Argon In Resealable Chemseal Bottles
75. Zinc Chloride, Anhydrous, Beads, Amorphous, -10 Mesh, 99.99% Trace Metals Basis
76. Zinc Chloride, Anhydrous, Beads, Amorphous, -10 Mesh, 99.999% Trace Metals Basis
77. Zinc Chloride, Anhydrous, Free-flowing, Redi-dri(tm), Reagent Grade, >=98%
78. Zinc Chloride, Puriss. P.a., Acs Reagent, Reag. Iso, Reag. Ph. Eur., >=98%
79. Zinc Chloride, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, 98-100.5%
80. Zinc Atomic Spectroscopy Standard Concentrate 1.00 G Zn, 1.00 G/l, For 1l Standard Solution, Analytical Standard
81. Zinc Chloride, Bioreagent, For Molecular Biology, Suitable For Cell Culture, Suitable For Insect Cell Culture
| Molecular Weight | 136.3 g/mol |
|---|---|
| Molecular Formula | Cl2Zn |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 133.866847 g/mol |
| Monoisotopic Mass | 133.866847 g/mol |
| Topological Polar Surface Area | 0 Ų |
| Heavy Atom Count | 3 |
| Formal Charge | 0 |
| Complexity | 2.8 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
| 1 of 2 | |
|---|---|
| Drug Name | Zinc chloride in plastic container |
| Active Ingredient | Zinc chloride |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | eq 1mg zinc/ml |
| Market Status | Prescription |
| Company | Hospira |
| 2 of 2 | |
|---|---|
| Drug Name | Zinc chloride in plastic container |
| Active Ingredient | Zinc chloride |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | eq 1mg zinc/ml |
| Market Status | Prescription |
| Company | Hospira |
Mesh Heading: Mouthwashes
National Library of Medicine, SIS; ChemIDplus Record for Zinc Chloride (7646-85-7). Available from, as of April 17, 2006: https://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
In low concentrations it is astringent and mildly antibacterial. It is used in vaginal douches to supress trichomonal and hemophilus infections. Although it is used in mouthwashes, contact time is too short, and only astringent and not antibacterial action results.
Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 722
MEDICATION (VET): Rare as caustic in fistulas (20% solution), as paste in chemotherapy of cancers, and on ulcers (2-4%). Some may still use it as antiseptic astringent on eye infections (0.1-0.2% solution).
Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 668
Astringent for corn and callus treatment
SRI
For more Therapeutic Uses (Complete) data for ZINC CHLORIDE (10 total), please visit the HSDB record page.
FDA Pregnancy Risk Category: C /RISK CANNOT BE RULED OUT. Adequate, well controlled human studies are lacking, and animal studies have shown risk to the fetus or are lacking as well. There is a chance of fetal harm if the drug is given during pregnancy; but the potential benefits may outweigh the potential risk./ /Zinc supplements; parenteral zinc/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006.
Zinc supplements should be taken at least 1 hour before or 2 hours after meals, since many foods may impair the absorption of zinc. If gastric irritation occurs, then zinc supplements may be taken with meals; however, the zinc will be less bioavailable. /Zinc supplements/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006.
In most cases, parenteral administration is indicated only when oral administration is not acceptable (for example, in nausea, vomiting, preoperative and postoperative conditions) or possible (for example, in malabsorption syndromes or following gastric resection). /Zinc supplements/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006.
Zinc injection that contains benzyl alcohol as a preservative should not be used in newborn and immature infants. The use of benzyl alcohol in neonates has been associated with a fatal toxic syndrome consisting of metabolic acidosis and CNS, respiratory, circulatory, and renal function impairment. /Zinc supplements/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006.
For more Drug Warnings (Complete) data for ZINC CHLORIDE (6 total), please visit the HSDB record page.
B - Blood and blood forming organs
B05 - Blood substitutes and perfusion solutions
B05X - I.v. solution additives
B05XA - Electrolyte solutions
B05XA12 - Zinc chloride
In humans subjected to low doses of (65)zinc chloride and whole-body measurements ... /it was/ estimated absorption to range from 58% to 77% in 5 controls, and from 16% to 42% in 3 patients suffering from acrodermatitis enterohepatica. The whole-body zinc retention was measured for 34 days ... One week after oral tracer dose of 2 ug zinc chloride to mice, the highest concentrations were found in bone tissue followed by liver and kidney.
Friberg, L., Nordberg, G.F., Kessler, E. and Vouk, V.B. (eds). Handbook of the Toxicology of Metals. 2nd ed. Vols I, II.: Amsterdam: Elsevier Science Publishers B.V., 1986., p. II:669
The whole-body retention at 95 hr after intravascular injection of carrier-free (65)zinc chloride to mature male rats amounted to 78.3% of the dose.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 2:261
In one study, 95 hr after injection of (65)zinc chloride to rats, 20.1% of the dose was recovered in feces and only 0.6% in urine ...
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 2:262
In mice given 0.3 ugzinc chloride iv, about 50% of the total dose was recovered in feces within a week. the corresponding value in 1 wk for dogs given 6.5 ug zinc chloride was about 20%. Urinary excretion for the same period was well below 5% of the dose in both species ... Biliary excretion of zinc in rats was found to be 4% over a period of 48 hr following a single iv dose of 0.1 mg (65)zinc chloride.
Friberg, L., Nordberg, G.F., Kessler, E. and Vouk, V.B. (eds). Handbook of the Toxicology of Metals. 2nd ed. Vols I, II.: Amsterdam: Elsevier Science Publishers B.V., 1986., p. II670
For more Absorption, Distribution and Excretion (Complete) data for ZINC CHLORIDE (17 total), please visit the HSDB record page.
For zinc, whole body: 162-500 days; [TDR, p. 1245]
TDR - Ryan RP, Terry CE, Leffingwell SS (eds). Toxicology Desk Reference: The Toxic Exposure and Medical Monitoring Index, 5th Ed. Washington DC: Taylor & Francis, 1999., p. 1245
Hepatocytes were grown in monolayer culture for 22 hr and subsequently treated with zinc chloride (100 uM) for 24 hr which produced a 15-fold increase in metallothionein proteins (MT) concentration. Following pretreatment with zinc chloride, hepatocytes were treated with 20 or 40 uM silver nitrate for 24 hr, and cytotoxicity was then assessed by enzyme leakage and loss of intracellular potassium. The toxicity of silver was significantly less in the zinc-pretreated cells. Furthermore, although zinc pretreatment had no appreciable effect on the hepatocellular uptake of silver, it did alter the subcellular distribution, and silver accumulated more in the cytosol and less in the nuclear, mitochondrial, and microsomal fractions. Silver in the cytosol of control cells was bound primarily to high molecular weight proteins, whereas silver was mainly associated with MT in the zinc-pretreated cells. Zinc-induced MT in rat primary hepatocyte cultures protects against silver-induced cytotoxicity which results from the binding of silver to MT with a concomitant reduction of metal content in critical organelles and proteins.
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 2:142
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