Athena Pharmaceutiques is a Partner of Choice for Drug Delivery & Life Cycle Management.

Contact Supplier

Kikkoman Biochemifa Company advances global health and safety through precision-driven innovation in biotech and food testing.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

11 Drugs in Development

11 Drugs in Development

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

11DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

API REF. PRICE (USD/KG)

$ 0

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Regulatory FDF Prices

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

API

FDF

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Mk-1084, Chembl4875422, Calderasib [inn], Yqf4art47c, Schembl23273000, Bdbm50572111

Molecular Formula

C₃₂H₃₁ClF₂N₆O₄

Molecular Weight

637.1 g/mol

InChI Key

BBIVCWWQPMOKAC-MSOLQXFVSA-N

FDA UNII

YQF4ART47C

1 2D Structure

MK-1084

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

19-chloro-22-[(2S,5R)-2,5-dimethyl-4-prop-2-enoylpiperazin-1-yl]-13,16-difluoro-3-propan-2-yl-8,11-dioxa-1,4,23,26-tetrazapentacyclo[16.6.2.02,7.012,17.021,25]hexacosa-2(7),3,5,12,14,16,18,20,22,25-decaen-24-one

2.1.2 InChI

InChI=1S/C32H31ClF2N6O4/c1-6-24(42)39-14-18(5)40(15-17(39)4)30-19-13-20(33)27-25-21(34)7-8-22(35)29(25)45-12-11-44-23-9-10-36-26(16(2)3)28(23)41(31(19)37-27)32(43)38-30/h6-10,13,16-18H,1,11-12,14-15H2,2-5H3/t17-,18+/m1/s1

2.1.3 InChI Key

BBIVCWWQPMOKAC-MSOLQXFVSA-N

2.2 Other Identifiers

2.2.1 UNII

YQF4ART47C

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Mk-1084

2. Chembl4875422

3. Calderasib [inn]

4. Yqf4art47c

5. Schembl23273000

6. Bdbm50572111

7. Mk1084

8. At48485

9. Hy-162431

10. Cs-1048397

2.4 Create Date

2021-08-21

3 Chemical and Physical Properties

Molecular Formula	C₃₂H₃₁ClF₂N₆O₄
Molecular Weight	637.1 g/mol
XLogP3	4.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	3
Exact Mass	Da
Monoisotopic Mass	Da
Topological Polar Surface Area	100
Heavy Atom Count	45
Formal Charge	0
Complexity	1160
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1